摘要
[目的]探析裘昌林教授辨治多系统萎缩的临证经验。[方法]通过跟师学习、整理医案等方式,以肾脑相济理伦为切入点,从理论基础、辨证论治及临证心法3个方面展开,分析总结裘昌林教授运用中医中药辨治多系统萎缩的临床经验,并例举医案予以验证。[结果]裘教授指出,肾脑之间在结构、生理及病理上相互联系,相互影响,脑髓之源滥觞于肾精;多系统萎缩(multiple system atrophy,MSA)病位在脑,多由虚损所致,兼或实邪为患,乃本虚标实之症,分列肾元亏虚、湿热浸淫、阴虚内热、肾阳虚衰为本病的主要分型;临证以补肾生髓为治本之法,兼以化瘀通络、升压定眩,对于治疗本病及改善临床症状疗效显著。所举医案,具体展示了上述辨证思路和治疗经验。[结论]裘教授从肾脑相济理论入手,正确认识多系统萎缩并以中医中药分证辨治该病疗效确定,副反应少,值得大力传承并予推广。
[Objective] To summarize Professor QIU Changlin's clinical experience on multiple system atrophy. [Methods] In the way of learning from the teacher and typical medical cases to analyze and summarize the Professor QIU Changlin 's clinical experience on multiple system atrophy from the coordinating kidney and brain via the etiology and pathogenesis, the clinical experience and the syndrome differentiation these three respects. Then enumerate medical records to validate it. [Results] Professor QIU points out: The structure, physiology and pathology of kidney and brain interrelate and influence each other. The origin of brain medulla originates from kidney essence; MSA locates in brain, which is caused by deficiency. It is a disease of deficiency and excess, which is divided into deficiency of liver and kidney, dampness and heat, heat in Yin deficiency and deficiency of kidney-Yang.Taking tonifying the kidney and promoting marrow as a permanent cure, removing blood stasis and clear collaterals, rising blood pressure and setting dizziness for the treatment of this disease. It is an effective option for relieving the clinical symptoms of the disease. And the method is helpful for clinical application. [Conclusion] Professor QIU Changlin correctly understanding multiple system atrophy and treating the disease with Chinese medicine with determined curative effect from the perspective of the kidney, less side effect, is worth inheriting and promoting vigorously.
引文
[1]Tada M,Onodera O,Tada M,et al.Early development of autonomic dysfunction may predict poor prognosis in patients with multiple system atrophy[J].Arch Neurol,2007,64(2):256-260.
[2]Nagai Y,Kitazawa R,Nakagawa M,et al.Multiple-system atrophy in long-term professional painter:A case report[J].Case Rep Pathol,2012,2012(1):613180.
[3]唐宗海.唐容川医学全书(精)[M].太原:山西科学技术出版社,2016:31.TANG Zonghai.TANG Rongchuan Medical Book(essence)[M].Taiyuan:Shanxi Science and Technology Press,2016:31.
[4]任继学.脑髓述要[J].中国中医基础医学杂志,2003,9(3):162.REN Jixue.A summary of the brain[J].Chinese Journal of Basic Medicine of Traditional Chinese Medicine,2003,9(3):162.
[5]蔡陆仙.中国医药汇海[M].北京:中国书店,1985:89.CAI Luxian.Huihai of Chinese Medicine[M].Beijing:China Bookstore,1985:89.
[6]陈士铎.石室秘录[M].北京:中国医药科技出版社,2011:138.CHEN Shiduo.Stone Room Secret[M].Beijing:China Medical Science and Technology Press,2011:138.
[7]张锡纯.医学衷中参西录[M].精华本.石家庄:河北科学技术出版社,2006.ZHANG Xichun.Intergrating Chinese and Western Medicine[M].The essence of the book.Shijiazhuang:Hebei Science and Technology Press,2006.
[8]何梦瑶.医碥[M].北京:中国中医药出版社,2009:289.HE Mengyao.Yi Bian[M].Beijing:China Press of Traditional Chinese Medicine,2009:289.
[9]陈修园.医学从众录[M].上海:上海科学技术出版社,1991:85-86.CHEN Xiuyuan.Yixue Congzhonglu[M].Shanghai:Shanghai Science and Technology Press,1991:85-86.
[10]赵培.圣济总录:上册[M].北京:人民卫生出版社,1962:655.ZHAO Pei.The Complete Record of Holy Benevolence:Volume 1[M].Beijing:People's Medical Publishing House,1962:655.
[11]杨荣禄,杨帆,杜晨旭,等.杨承芝教授补肾化痰活血三法论治老年性痴呆经验浅析[J].浙江中医药大学学报,2017,41(11):873-876.YANG Ronglu,YANG Fan,DU Chenxu,et al.Professor YANG Chengzhi's experience in treating senile dementia by three methods of tonifying kidney,resolving phlegm and activating blood circulation[J].Journal of Zhejiang Chinese Medicine University,2017,41(11):873-876.
[12]赵德智,鲍超,陈栋.浅析吴旭教授从肾脑论治脑瘫的理论依据[J].浙江中医药大学学报,2018,42(3):197-199.ZHAO Dezhi,BAO Chao,CHEN Dong.A brief analysis of Professor WU Xu's theoretical basis for treating Cerebral Palsy from Kidney-brain Theory[J].Journal of Zhejiang Chinese Medicine University,2018,42(3):197-1999.
[13]张介宾.景岳全书[M].北京:人民卫生出版社,2007:1248.ZHANG Jiebin.Jingyue's Complete Works[M].Beijing:People's Medical Publishing House,2007:1248.
[14]任继学.脑髓述要[J].中国中医基础医学杂志,2003,9(3):161-163.REN Jixue.A summary of the brain[J].China Journal of Basic Medicine in Traditional Chinese Medicine,2003,9(3):161-163.
[15]李林,魏海峰,张兰,等.中医”肾生髓,脑为髓海”现代生物学基础探讨[J].中国中医杂志,2006,31(17):1397-1400.LI Lin,WEI Haifeng,ZHANG Lan,et al.Discussion on the modern biological basis of"kidney generating marrow and brain serving as Sui Hai"in traditional Chinese medicine[J].Chinese Journal of Chinese Materia Medica,2006,31(17):1397-1400.