吲哚菁绿清除试验在肝病中的临床应用
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摘要
吲哚菁绿(ICG)清除试验是临床上评估肝脏储备功能准确而实用的一种检查方法 ,近年来吲哚菁绿在清除试验在肝脏损伤诊断中运用逐渐增多,该方式诊断时具有无创、快速特点,可了解患者实际肝脏损伤程度,了解患者实时病情,对各种肝病进行早期诊断筛查、早期警示肝功能不全或隐匿性肝脏疾病、早期判断预后。该试验相对于胆红素、凝血酶原时间等化验指标、Child-Pugh评分更具有优越性和科学性,能更好地指导临床治疗或手术方案的建立以及治疗效果的评判,因此在肝脏疾病的诊疗中具有较大的临床价值。
The indocyanine green(ICG) clearance test is an accurate and practical method for clinically evaluating liver reserve function. In recent years, indocyanine green has been increasingly used in the diagnosis of liver injury in the removal test of non-invasive, rapid characteristics, can understand the actual degree of liver damage, understand the real-time condition of patients, early diagnosis screening of various liver diseases, early warning of liver dysfunction or occult liver disease, early judgment of prognosis. The test is superior and scientific with respect to the bilirubin, prothrombin time and other laboratory indicators, child-Pugh score, and can better guide the establishment of clinical treatment or surgical plan and the evaluation of therapeutic effects, so liver disease has great clinical value in the diagnosis and treatment.
The indocyanine green(ICG) clearance test is an accurate and practical method for clinically evaluating liver reserve function. In recent years, indocyanine green has been increasingly used in the diagnosis of liver injury in the removal test of non-invasive, rapid characteristics, can understand the actual degree of liver damage, understand the real-time condition of patients, early diagnosis screening of various liver diseases, early warning of liver dysfunction or occult liver disease, early judgment of prognosis. The test is superior and scientific with respect to the bilirubin, prothrombin time and other laboratory indicators, child-Pugh score, and can better guide the establishment of clinical treatment or surgical plan and the evaluation of therapeutic effects, so liver disease has great clinical value in the diagnosis and treatment.
引文
[1]王宏光,许寅喆,陈明易,等.吲哚菁绿荧光融合影像引导在腹腔镜解剖性肝切除术中的应用价值[J].中华消化外科杂志,2017,16(4):405-409.
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[4]李向阳,唐哲,高志强,等.吲哚菁绿试验评估肝脏良恶性疾病肝脏储备功能的应用现状及发展前景[J].腹部外科,2017,30(2):149-151.
[5]黄丽雯,张灵.吲哚菁绿清除试验在肝脏储备功能评估及肝衰竭预后判断中的价值分析[J].西南军医,2016,18(3):254-256.
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[8]田瑞民,刘国旺,魏巍,等.吲哚菁绿15 min滞留率在肝储备功能评估中的价值探讨[J].天津医药,2016,44(9):1136-1138.
[9]赖瑞敏,吴银莲,董菁,等.吲哚菁绿试验对HBV相关肝脏疾病的肝脏储备功能及预后评估价值[J].肝脏,2016,21(11):908-910.
[10]吉斐,韩明,张志衡,等.吲哚菁绿清除试验在肝移植后肝功能评估中的价值[J].中华器官移植杂志,2016,37(3):139-143.
[11]唐哲,任浩,李向阳,等.吲哚菁绿试验对小肝癌手术方式选择的指导价值[J].中华实验外科杂志,2017,34(1):123-126.
[12]姚舜禹,荚卫东,王润东,等.吲哚菁绿荧光融合影像引导精准右半肝切除治疗肝细胞癌临床研究[J].中国实用外科杂志,2018,38(4):430-434.
[2]余柳丹,罗一帆,陈小菊,等.吲哚菁绿稳定性及光敏性和声敏性研究[J].化学研究与应用,2016,28(3):400-403.
[3]Levesque E,Martin E,Dudau D,et al.Current use and perspective of indocyanine green clearance in liver diseases[J].Anaesth Crit Care Pain Med,2016,35(1):49-57.
[4]李向阳,唐哲,高志强,等.吲哚菁绿试验评估肝脏良恶性疾病肝脏储备功能的应用现状及发展前景[J].腹部外科,2017,30(2):149-151.
[5]黄丽雯,张灵.吲哚菁绿清除试验在肝脏储备功能评估及肝衰竭预后判断中的价值分析[J].西南军医,2016,18(3):254-256.
[6]Sagawa E,Okubo H,Sorin Y,et al.Use of finger-piece method for indocyanine green clearance test[J].Hepatology Research,2017,47(12):29-32.
[7]王铭,唐红.吲哚菁绿清除试验的临床应用[J].临床肝胆病杂志,2017,33(6):1183-1187.
[8]田瑞民,刘国旺,魏巍,等.吲哚菁绿15 min滞留率在肝储备功能评估中的价值探讨[J].天津医药,2016,44(9):1136-1138.
[9]赖瑞敏,吴银莲,董菁,等.吲哚菁绿试验对HBV相关肝脏疾病的肝脏储备功能及预后评估价值[J].肝脏,2016,21(11):908-910.
[10]吉斐,韩明,张志衡,等.吲哚菁绿清除试验在肝移植后肝功能评估中的价值[J].中华器官移植杂志,2016,37(3):139-143.
[11]唐哲,任浩,李向阳,等.吲哚菁绿试验对小肝癌手术方式选择的指导价值[J].中华实验外科杂志,2017,34(1):123-126.
[12]姚舜禹,荚卫东,王润东,等.吲哚菁绿荧光融合影像引导精准右半肝切除治疗肝细胞癌临床研究[J].中国实用外科杂志,2018,38(4):430-434.