广州市白云区农村绝经妇女子宫内膜病变流行病学调查及子宫内膜细胞学检查子宫内膜癌应用

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英文篇名：Epidemiological investigation of endometrial disease and applications of endometrial cytology in endometrial carcinoma among rural menopause women in Baiyun district of Guangzhou city 作者：欧素兰 英文作者：OU Su Lan;The Third People's Hospital of Baiyun District Guangzhou City; 关键词：农村绝经妇女 ; 子宫内膜病变 ; 流行病学调查 ; 子宫内膜细胞学检查 ; 子宫内膜癌 英文关键词：rural postmenopausal women;;endometrial lesions;;epidemiological survey;;endometrial cytology;;endometrial carcinoma 中文刊名：YZWS 英文刊名：Chinese Journal of Women and Children Health 机构：广东省广州市白云区第三人民医院; 出版日期：2018-01-20 出版单位：中国妇幼卫生杂志 年：2018 期：v.9 基金：广州市医药卫生科技项目(2015A010119)—广州市白云区农村绝经妇女子宫内膜病变流行病学调查及子宫内膜细胞学检查子宫内膜癌应用 语种：中文; 页：YZWS201801016 页数：4 CN：01 ISSN：11-5816/R 分类号：63-66

摘要

目的了解广州市白云区农村绝经妇女子宫内膜病变发病情况及子宫内膜细胞学筛查在子宫内膜癌筛查中的应用价值。方法于2015年5月-2016年10月对广州市白云区绝经后农村妇女进行前瞻性调查研究,由妇科医师严格填写"绝经后妇女子宫内膜病变流行病学调查表",采用整群抽样调查方法抽取所有子宫内膜病变患者的数据。针对性行子宫内膜细胞学取样与液基薄层细胞学技术结合制片后加上必要的病理检查。结果 129例妇女中,22例有子宫内膜病变症状,19例存在子宫内膜癌高危因素;子宫内膜细胞学检查发现15例为子宫内膜病变,其中12例患者的内膜细胞学检查结果与病理检查结果符合。子宫内膜细胞学检查子宫内膜癌的准确性、敏感性、特异性分别为86.67%、75.00%、88.89%。病理检查符合妇女随访3个月、6个月的子宫内膜厚度均大于病理检查不符合的妇女。结论广州市白云区农村绝经妇女子宫内膜疾病的发病形式较严峻,子宫内膜细胞学是筛查子宫内膜癌的有效方法。
        Objective To investigate the incidence of endometrial lesions and the value of endometrial cytology in endometrial carcinoma screening among rural menopause women in Baiyun District of Guangzhou City. Methods From May 2015 to October2016,a prospective investigation was conducted on rural postmenopausal women in Baiyun District,Guangzhou. The gynecologist strictly filled in the Epidemiological Survey of Endometriosis in Postmenopausal Women. A cluster sampling method was used to extract the data of all patients with endometrial lesions. According to the symptoms and high risk factors of the women,the endometrial cytology sampling and liquid-based thin-layer cytology were combined to use. Then,according to the results of cytology, the pathological examination was used. Results Of the 129 women,22 women had endometrial lesions and 19 women had high risk factors of endometrial cancer. In the endometrial cytology examination,15 were endometrial lesions. Among them,12 were consistent with the results of pathological examination. The accuracy,sensitivity and specificity of endometrial cytology for endometrial carcinoma were 86. 67%,75. 00% and 88. 89%,respectively. The endometrial thicknesses of patients with consistent results were larger than those with inconsistent results when follow-up in 3 months and in 6 months. Conclusion The incidence of endometrial disease in rural menopausal women in Baiyun District of Guangzhou City is more serious. Endometrial cytology is an effective method to screen endometrial carcinoma.

引文

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