CO_2激光与等离子两种方法治疗喉乳头状瘤的疗效对比

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英文篇名：Comparative study on Therapeutic Effectiveness of CO_2 Laser and Low-temperature Plasma on Laryngeal Papilloma 作者：魏锐文 ; 范敏 ; 崔榕 ; 蒋锐明 ; 蒋亚林 英文作者：Wei Ruiwen;Fan Min;Cui Rong;Chengdu Seventh People's Hospital;Chengdu Tenth People's Hospital; 关键词：喉乳头状瘤 ; CO2激光 ; 低温等离子 英文关键词：laryngeal papilloma;;Co2 laser;;low-temperature plasma 中文刊名：SCYX 英文刊名：Sichuan Medical Journal 机构：成都市第七人民医院;成都市第十人民医院; 出版日期：2017-07-15 出版单位：四川医学 年：2017 期：v.38 语种：中文; 页：SCYX201707024 页数：4 CN：07 ISSN：51-1144/R 分类号：73-76

摘要

目的评估两种方法治疗喉乳头状瘤的疗效及安全性。方法随机将63喉乳头状瘤患者分为两组,A组采用显微镜下CO_2激光切除,B组采用7070号低温等离子射频刀头切除。比较两组患者的声带粘连、术后复发及恶变情况。结果 CO_2激光治疗组较等离子治疗组复发率低,差异有统计学意义(P=0.027);对单发病灶患者,CO_2激光治疗组较等离子治疗组复发率低,差异有统计学意义(P=0.040);对多发病灶患者,CO_2激光治疗组与等离子治疗组复发率比较,差异无统计学意义(P=0.395);CO_2激光治疗组较等离子治疗组声带粘连发生率低,差异有统计学意义(P=0.027)。复发主要发生在术后12个月以内,尤其是术后6个月。结论 CO_2激光治疗喉乳头状瘤安全、有效,并发症少。
        Objective To evaluate the efficacy and safety of CO_2 laser and low-temperature plasma. Methods 63 patients with laryngeal papilloma were randomly divided into two groups.A group was treated with CO_2 laser under microscope while B group was treated with CoblatorT M Reflex#7070.Vocal cord adhesion,postoperative recurrence and malignant transformation of two groups were compared.Results CO_2 laser group had a lower rate of recurrence than low-temperature plasma group( P = 0. 027).For patients with single lesion,CO_2 laser group had a lower rate of recurrence than low-temperature plasma group( P = 0. 040).For patients with multiply lesions,there were no statistical differences between two groups( P = 0. 395).Compared with low-temperature plasma group,the incidence of vocal cord adhesion in CO_2 laser group was lower( P = 0. 027). The recurrence mainly happened within 12 months after operation,especially within 6 months after operation.Conclusion CO_2 laser is safe and efficient and causes few complications in the treatment of laryngeal papilloma.

引文

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