舒胃汤联合四联疗法治疗肝胃郁热型消化性溃疡50例
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摘要
目的:观察舒胃汤联合四联疗法治疗肝胃郁热型消化性溃疡的疗效和安全性。方法:对照组50例患者给予四联疗法治疗;治疗组50例患者在此基础上联合自拟舒胃汤治疗,4周疗程结束后,对疗效进行评价,并记录治疗过程中的不良反应。结果:疗程结束后两组主、次症积分均较治疗前明显降低,与治疗前比较差异具有显著性(P<0.05)。治疗组主、次症积分降低幅度明显大于对照组(P<0.05)。治疗组胃镜检查与中医症候疗效总有效率分别为82.0%、92.0%,对照组分别为60%、74.0%(P<0.05)。两组HP清除率分别为92%和86%,差异无显著性(P>0.05)。治疗组根除率为88%,明显高于对照组,复发率为6%,低于对照组,差异具有显著性(P<0.05)。两组均无明显不良反应病例。结论:舒胃汤联合四联疗法可迅速改善患者临床症状,提高疗效,减少复发,是肝胃郁热型消化性溃疡患者安全有效的治疗方案。
Objective:To observe the Weishu decoction combined with quadruple therapy efficacy and safety of treating stagnated heat of liver and stomach type peptic ulcer.Methods:In our hospital in 2013June~2014June 100 cases accorded with the diagnostic standard of cases with occult,randomly divided into two groups,50 cases were treated with quadruple therapy as the control group;the treatment group 60 patients on the basis of Weishu decoction,the end of the 4week after treatment,to evaluate efficacy,and record the adverse reactions in the course of treatment.Results:After the treatment of two groups of main,secondary symptoms were significantly lower than that before treatment,compare with before treatment,the difference was significant(P<0.05).The treatment group of main,secondary symptoms were significantly less than those of the control group(P<0.05).The treatment group of gastroscopy and TCM syndrome curative effect total effective rate were 82%,92%,60%,74% in control group respectively(P<0.05).Two groups of HP clearance rates were 92% and 86%,no significant difference(P>0.05).The treatment group the eradication rate was 88%,significantly higher than that in the control group,the recurrence rate was 6%,lower than that of the control group,the difference was significant(P<0.05).The two groups had no obvious adverse reaction cases.Conclusion:Weishu decoction combined with quadruple therapy can rapidly improve the clinical symptoms,patients can improve the curative effect,reduce the recurrence,is a safe and effective treatment of liver stomach heat type of peptic ulcer patients.
Objective:To observe the Weishu decoction combined with quadruple therapy efficacy and safety of treating stagnated heat of liver and stomach type peptic ulcer.Methods:In our hospital in 2013June~2014June 100 cases accorded with the diagnostic standard of cases with occult,randomly divided into two groups,50 cases were treated with quadruple therapy as the control group;the treatment group 60 patients on the basis of Weishu decoction,the end of the 4week after treatment,to evaluate efficacy,and record the adverse reactions in the course of treatment.Results:After the treatment of two groups of main,secondary symptoms were significantly lower than that before treatment,compare with before treatment,the difference was significant(P<0.05).The treatment group of main,secondary symptoms were significantly less than those of the control group(P<0.05).The treatment group of gastroscopy and TCM syndrome curative effect total effective rate were 82%,92%,60%,74% in control group respectively(P<0.05).Two groups of HP clearance rates were 92% and 86%,no significant difference(P>0.05).The treatment group the eradication rate was 88%,significantly higher than that in the control group,the recurrence rate was 6%,lower than that of the control group,the difference was significant(P<0.05).The two groups had no obvious adverse reaction cases.Conclusion:Weishu decoction combined with quadruple therapy can rapidly improve the clinical symptoms,patients can improve the curative effect,reduce the recurrence,is a safe and effective treatment of liver stomach heat type of peptic ulcer patients.
引文
[1]苏文台,孙薇.中医辨证治疗对消化性溃疡并幽门螺杆菌感染患者的疗效影响[J].陕西中医,2011,32(10):1318-1319.
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[7]乔冠卿,马文辉,姚博,等.聚脉证——调胃舒郁汤治疗思路探讨[J].光明中医,2013,28(4):674-676.
[8]李刚,崔桂娟.黄芪建中汤合良附丸加减治疗脾胃虚寒型消化性溃疡100例疗效观察[J].河北中医,2011,33(1):66-67.
[9]酒龙根,陈振样,侯靖武,等.中西医结合治疗消化性溃疡76例疗效观察[J].中医临床研究,2011,03(8):33-34.
[10]肖高健.半夏汤联合三联疗法治疗老年消化性溃疡的临床效果观察[J].中外医疗,2013,32(20):141-142.
[11]王捷虹,惠建萍.沈舒文运用经方治疗消化系统疾病验案[J].河南中医,2012,32(6):675-677.
[12]张小红.消化性溃疡180例诱因分析[J].陕西医学杂志,2011,40(2):247-248.
[2]赵殿和,狄建宁.舒肝和胃汤治疗消化性溃疡92例[J].中国医药导报,2006,3(27):123.
[3]陈岩,姜树坤.舒肝益胃汤治疗消化性溃疡160例[J].中国民间疗法,2010,18(5):30.
[4]岳士才.岳氏溃疡冲剂治疗消化性溃疡脾胃气虚、气滞血瘀型临床总结[J].中医药临床杂志,2011,23(8):711-713.
[5]钟克武.柴贝舒肝健胃汤治疗消化性溃疡病临床观察[J].中医学报,2010,25(1):135-136.
[6]曹建华.自拟胃疡汤治疗消化性溃疡45例报告[J].中外医疗,2009,28(21):104-105.
[7]乔冠卿,马文辉,姚博,等.聚脉证——调胃舒郁汤治疗思路探讨[J].光明中医,2013,28(4):674-676.
[8]李刚,崔桂娟.黄芪建中汤合良附丸加减治疗脾胃虚寒型消化性溃疡100例疗效观察[J].河北中医,2011,33(1):66-67.
[9]酒龙根,陈振样,侯靖武,等.中西医结合治疗消化性溃疡76例疗效观察[J].中医临床研究,2011,03(8):33-34.
[10]肖高健.半夏汤联合三联疗法治疗老年消化性溃疡的临床效果观察[J].中外医疗,2013,32(20):141-142.
[11]王捷虹,惠建萍.沈舒文运用经方治疗消化系统疾病验案[J].河南中医,2012,32(6):675-677.
[12]张小红.消化性溃疡180例诱因分析[J].陕西医学杂志,2011,40(2):247-248.