声触诊组织成像定量技术评价正常成人睾丸生精功能
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摘要
目的采用声触诊组织成像定量(VTIQ)技术测量正常成人睾丸剪切波速度(SWV),分析影响睾丸弹性硬度的主要因素,探讨其评价男性睾丸生精功能的价值。方法招募200名正常成年男性志愿者行睾丸常规超声检查,测量双侧睾丸体积。以VTIQ技术测量双侧睾丸上极、中份、下极的SWV,比较双侧睾丸、不同年龄组睾丸SWV差异,并与年龄、睾丸体积和精子活动率和精子密度进行相关性分析。结果200名正常成年男性左右侧睾丸SWV均为(1.23±0.18)m/s,左右侧差异无统计学意义(t=-0.376,P=0.710)。21～30岁组、31～40岁组、41～50岁与51～60岁组间双侧睾丸SWV值总体差异均有统计学意义(P均<0.001)。睾丸SWV与年龄呈正相关(r=0.454,P<0.001),与睾丸体积、精子活动率和精子密度分别呈负相关(r=-0.649、-0.668、-0.675,P均<0.001)。结论 VTIQ技术可定量测量睾丸组织硬度,有望用于初步评估睾丸生精功能。
Objective To measure the shear wave velocity (SWV)of normal adult testis using virtual touch tissue imaging quantification (VTIQ),and to analyze the main impact factors of testicular stiffness and the value of VTIQ in evaluation of testicular spermatogenesis.Methods Totally 200 normal adult male volunteers were recruited and underwent routine testicular ultrasonography for the measurement of bilateral testicular volume.VTIQ technique was used to measure SWV of the upper,middle and lower poles of the bilateral testis.The differences of SWV in bilateral testis and testis of different age groups were compared.The correlation of SWV with age,testicular volume and sperm motility and density was analyzed.Results SWV of both the left and right lateral testis of 200 normal adult males were (1.23±0.18)m/s,and no statistically significant difference was found (t=-0.376,P=0.710).There were significant differences of SWV among the 21—30 years old group,31—40 years old group,41—50 years old and 51—60 years old group (all P<0.001).Testicular SWV was positively correlated with age (r=0.454,P<0.001)and negatively correlated with testicular volume,sperm motility and density (r=-0.649,-0.668,-0.675,all P <0.001).Conclusion VTIQ technique can quantitatively measure testicular tissue hardness,which may be used to initially evaluate testicular spermatogenesis.
Objective To measure the shear wave velocity (SWV)of normal adult testis using virtual touch tissue imaging quantification (VTIQ),and to analyze the main impact factors of testicular stiffness and the value of VTIQ in evaluation of testicular spermatogenesis.Methods Totally 200 normal adult male volunteers were recruited and underwent routine testicular ultrasonography for the measurement of bilateral testicular volume.VTIQ technique was used to measure SWV of the upper,middle and lower poles of the bilateral testis.The differences of SWV in bilateral testis and testis of different age groups were compared.The correlation of SWV with age,testicular volume and sperm motility and density was analyzed.Results SWV of both the left and right lateral testis of 200 normal adult males were (1.23±0.18)m/s,and no statistically significant difference was found (t=-0.376,P=0.710).There were significant differences of SWV among the 21—30 years old group,31—40 years old group,41—50 years old and 51—60 years old group (all P<0.001).Testicular SWV was positively correlated with age (r=0.454,P<0.001)and negatively correlated with testicular volume,sperm motility and density (r=-0.649,-0.668,-0.675,all P <0.001).Conclusion VTIQ technique can quantitatively measure testicular tissue hardness,which may be used to initially evaluate testicular spermatogenesis.
引文
[1]刘丽莉,冯岚,陶阳,等.剪切波弹性成像鉴别诊断桥本甲状腺炎合并甲状腺结节的性质.中国医学影像技术,2017,33(8):1202-1205.
[2]Kapetas P,Clauser P,Woitek R,et al.Virtual Touch IQelastography reduces unnecessary breast biopsies by applying quantitative"rule-in"and"rule-out"threshold values.Sci Rep,2018,8(1):3583.
[3]Ben Z,Gao S,Wu W,et al.Clinical value of the VTIQtechnology in the differential diagnosis of superficially enlarged lymph nodes.Acta Radiol,2018,59(7):836-844.
[4]郭燕荣,董常峰,林浩铭,等.声辐射力脉冲弹性成像技术评估大鼠非酒精性脂肪肝及肝纤维化.中国医学影像技术,2017,33(9):1315-1320.
[5]Sakamoto H,Saito K,Oohta M,et al.Testicular volume measurement:Comparison of ultrasonography,orchidometry,and water displacement.Urology,2007,69(1):152-157.
[6]Ophir J,Cespedes I,Ponnekanti H,et al.Elastography:Aquantitative method for imaging the elasticity of biological tissues.Ultrason Imaging,1991,13(2):111-134.
[7]Yavuz A,Yokus A,Taken K,et al.Reliability of testicular stiffness quantification using shear wave elastography in predicting male fertility:A preliminary prospective study.Med Ultrason,2018,20(2):141-147.
[8]Trottmann M,Marcon J,D'anastasi M,et al.The role of VTIQas a new tissue strain analytics measurement technique in testicular lesions.Clin Hemorheol Microcirc,2014,58(1):195-209.
[9]Marcon J,Trottmann M,Rubenthaler J,et al.Shear wave elastography of the testes in a healthy study collective-differences in standard values between ARFI and VTIQ techniques.Clin Hemorheol Microcirc,2016,64(4):721-728.
[10]毛林.剪切波弹性成像技术在正常睾丸-附睾和急性附睾炎治疗前后应用价值的初步研究.广州:广州医科大学,2017:12-16.
[11]黄崑,姜镔,刘艳君,等.实时剪切波弹性成像技术定量评价正常成人睾丸、附睾.解剖科学进展,2015,21(3):334-336.
[12]D'Anastasi M,Schneevoigt BS,Trottmann M,et al.Acoustic radiation force impulse imaging of the testes:A preliminary experience.Clin Hemorheol Microcirc,2011,49(1-4):105-114.
[13]Kurtz MP,Zurakowski D,Rosoklija I,et al.Semen parameters in adolescents with varicocele:Association with testis volume differential and total testis volume.J Urol,2015,193(5Suppl):1843-1847.
[14]闫雷,戚庭月,孙红光,等.VTIQ技术取样框大小对乳腺结节剪切波速度的影响.中国超声医学杂志,2017,33(12):1071-1074.
[2]Kapetas P,Clauser P,Woitek R,et al.Virtual Touch IQelastography reduces unnecessary breast biopsies by applying quantitative"rule-in"and"rule-out"threshold values.Sci Rep,2018,8(1):3583.
[3]Ben Z,Gao S,Wu W,et al.Clinical value of the VTIQtechnology in the differential diagnosis of superficially enlarged lymph nodes.Acta Radiol,2018,59(7):836-844.
[4]郭燕荣,董常峰,林浩铭,等.声辐射力脉冲弹性成像技术评估大鼠非酒精性脂肪肝及肝纤维化.中国医学影像技术,2017,33(9):1315-1320.
[5]Sakamoto H,Saito K,Oohta M,et al.Testicular volume measurement:Comparison of ultrasonography,orchidometry,and water displacement.Urology,2007,69(1):152-157.
[6]Ophir J,Cespedes I,Ponnekanti H,et al.Elastography:Aquantitative method for imaging the elasticity of biological tissues.Ultrason Imaging,1991,13(2):111-134.
[7]Yavuz A,Yokus A,Taken K,et al.Reliability of testicular stiffness quantification using shear wave elastography in predicting male fertility:A preliminary prospective study.Med Ultrason,2018,20(2):141-147.
[8]Trottmann M,Marcon J,D'anastasi M,et al.The role of VTIQas a new tissue strain analytics measurement technique in testicular lesions.Clin Hemorheol Microcirc,2014,58(1):195-209.
[9]Marcon J,Trottmann M,Rubenthaler J,et al.Shear wave elastography of the testes in a healthy study collective-differences in standard values between ARFI and VTIQ techniques.Clin Hemorheol Microcirc,2016,64(4):721-728.
[10]毛林.剪切波弹性成像技术在正常睾丸-附睾和急性附睾炎治疗前后应用价值的初步研究.广州:广州医科大学,2017:12-16.
[11]黄崑,姜镔,刘艳君,等.实时剪切波弹性成像技术定量评价正常成人睾丸、附睾.解剖科学进展,2015,21(3):334-336.
[12]D'Anastasi M,Schneevoigt BS,Trottmann M,et al.Acoustic radiation force impulse imaging of the testes:A preliminary experience.Clin Hemorheol Microcirc,2011,49(1-4):105-114.
[13]Kurtz MP,Zurakowski D,Rosoklija I,et al.Semen parameters in adolescents with varicocele:Association with testis volume differential and total testis volume.J Urol,2015,193(5Suppl):1843-1847.
[14]闫雷,戚庭月,孙红光,等.VTIQ技术取样框大小对乳腺结节剪切波速度的影响.中国超声医学杂志,2017,33(12):1071-1074.