基于肠道菌群的2型糖尿病中医“胃强”理论探微
摘要
中医学从"胃强"理论论治2型糖尿病具有积极的临床意义,而现代研究证实,2型糖尿病的发生与肠道菌群存在密切联系,调节肠道菌群可以改善糖脂代谢紊乱、胰岛素抵抗等状况,因此,肠道菌群成为从"胃强"论治2型糖尿病新的研究靶点。文章通过结合肠道菌群的角度,对2型糖尿病之中医"胃强"理论进行深入的探析和论述。
引文
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[7]周建龙,岳仁宋,邓朵朵,等.从挽精逐浊法论治代谢性疾病[J].中华中医药杂志,2017,32(2):593-595.
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[11]吴深涛.论浊毒与糖尿病糖毒性和脂毒性的相关性[J].中医杂志,2004,45(9):647-649.
[12]吕金仓.浊毒致郁论[J].河北中医,2013,35(5):671-672.
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[14]Donath M Y,Steven S E.Type 2 diabetes as an inflammatory disease[J].Nat Rev Immunol,2011,11(2):98-107.
[15]朱春英,张英福,李志红,等.幽门螺旋杆菌感染与糖尿病的相关性[J].河北医学,2017,39(3):445-447.
[16]巩静,陈广,王定坤,等.从脾胃论治糖尿病与肠道菌群的关系[J].中国中西医结合杂志,2016,36(4):484-486.
[17]白煜,白宇宁,连凤梅.仝小林辨治肥胖型2型糖尿病脂代谢紊乱临证思路[J].中华中医药杂志,2017,32(3):1114-1116.
[18]黄永坤.胃肠道菌群和胃肠黏膜屏障的检测[J].中国实用儿科杂志,2010,25(7):516-518.
[19]Agrawal RP,Sharma R,Garg D,et al.Role of Helicobacter pylofi in causation of diabetic gastropathies and non gastrointestinal complications in type 2 diabetes[J].J Indian Med Assoc,2010,108(3):140-143.
[20]黄敏,刘慧玲.2型糖尿病患者幽门螺旋杆菌感染的临床分析及综合干预研究[J].中华医院感染学杂志,2014,24(7):1697-1699.
[2]成无己.注解伤寒论[M].北京:人民卫生出版社,1963:145-146.
[3]朱文峰.中医诊断学[M].北京:中国中医药出版社,2003:28.
[4]蔡小平,周宜强,朱艳琴.糖尿病证治新理论---“脾弱胃强”观[J].中国中医基础医学杂志,2003,9(5):25-26.
[5]王醊恩,杨毅.也谈“胃强脾弱”[J].长春中医药大学学报,2010,26(3):464-465.
[6]仝小林,刘文科,甄仲.从2型糖尿病的诊疗谈“壮火食气,气食少火”[J].中国中医基础医学杂志,2008,14(7):523-524.
[7]周建龙,岳仁宋,邓朵朵,等.从挽精逐浊法论治代谢性疾病[J].中华中医药杂志,2017,32(2):593-595.
[8]Murphy EF,Cotter PD,Healy S,et al.Composition and energy harvesting capacity of gut microbiota:relationship to diet,obesity and time in mouse models[J].Gut,2010(12),59:1635-1642.
[9]Awdeh ZL,Yunis EJ,Audeh MJ,et al.A genetic explanation for the rising incidence of type 1 diebeties,a polygenic disease[J].J Autoimmun,2006,27(3):174-181.
[10]Backhed F,Ding H,Wang T,et al.The gut microbiota as an environmental factor that regulates fat storage[J].Proc Natl Acad Sci U SA,2004,101(44):15718-15723.
[11]吴深涛.论浊毒与糖尿病糖毒性和脂毒性的相关性[J].中医杂志,2004,45(9):647-649.
[12]吕金仓.浊毒致郁论[J].河北中医,2013,35(5):671-672.
[13]Caricilli A M,Saad M J.The role of gut microbiota on insulin resistance[J].Nutrients,2013,5(3):829-851.
[14]Donath M Y,Steven S E.Type 2 diabetes as an inflammatory disease[J].Nat Rev Immunol,2011,11(2):98-107.
[15]朱春英,张英福,李志红,等.幽门螺旋杆菌感染与糖尿病的相关性[J].河北医学,2017,39(3):445-447.
[16]巩静,陈广,王定坤,等.从脾胃论治糖尿病与肠道菌群的关系[J].中国中西医结合杂志,2016,36(4):484-486.
[17]白煜,白宇宁,连凤梅.仝小林辨治肥胖型2型糖尿病脂代谢紊乱临证思路[J].中华中医药杂志,2017,32(3):1114-1116.
[18]黄永坤.胃肠道菌群和胃肠黏膜屏障的检测[J].中国实用儿科杂志,2010,25(7):516-518.
[19]Agrawal RP,Sharma R,Garg D,et al.Role of Helicobacter pylofi in causation of diabetic gastropathies and non gastrointestinal complications in type 2 diabetes[J].J Indian Med Assoc,2010,108(3):140-143.
[20]黄敏,刘慧玲.2型糖尿病患者幽门螺旋杆菌感染的临床分析及综合干预研究[J].中华医院感染学杂志,2014,24(7):1697-1699.