李达从毒辨治血液肿瘤思路与临证经验
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摘要
恶性血液肿瘤多数起病急,变化快,病情重。李达教授据三十载血液病临证经验,总结其因毒致病、因病致虚的病机特点,认为白血病因温毒致病,属"血癌"范畴,病位在骨髓,病机为精气亏虚,伏邪内陷,邪正交争所致,变化多端,属于难治之证;淋巴瘤属"恶核"范畴,因痰毒致病,病位在三焦,病机本质为脾虚痰积;骨髓瘤属"髓瘤"范畴,因瘀毒致病,病位在骨髓,与肾相关,肾虚血瘀毒蕴为其病机本质。临证从毒辨治,以毒攻毒、和解排毒、解毒生血,共奏扶正祛邪、固本澄源之效。
Hematologic malignancies are characterized by acute onset, critically illness, and progressing rapidly.Based on the clinical experience of thirty years in treating hematological diseases professor LI Da summarizes the pathogenesis characteristics of the disease caused by toxin causing disease and asthenia due to illness. Leukemia is caused by febrile virulence and is located in bone marrow belongs to ‘blood cancer'. Pathogenesis is due to deficiency of vital energy, sinking of underlying pathogenic factors, orthogonal disputes of pathogenic factors, and various changes, which belong to intractable syndrome. Lymphoma belongs to the category of ‘malignant nucleus'. It is caused by phlegm and toxin. It is located in Sanjiao,and its pathogenesis is essentially spleen deficiency and phlegm accumulation. Myeloma belongs to the category of ‘myeloma'.It is caused by blood stasis and toxin. It is located in bone marrow and related to kidney. Its pathogenesis is essentially kidney deficiency, blood stasis and toxin accumulation. Clinical treatment from toxin evil, fight poison, reconciliation detoxification,detoxication and engendering blood, played the total effect of strengthening the body resistance and eliminate pathogenic factors.
Hematologic malignancies are characterized by acute onset, critically illness, and progressing rapidly.Based on the clinical experience of thirty years in treating hematological diseases professor LI Da summarizes the pathogenesis characteristics of the disease caused by toxin causing disease and asthenia due to illness. Leukemia is caused by febrile virulence and is located in bone marrow belongs to ‘blood cancer'. Pathogenesis is due to deficiency of vital energy, sinking of underlying pathogenic factors, orthogonal disputes of pathogenic factors, and various changes, which belong to intractable syndrome. Lymphoma belongs to the category of ‘malignant nucleus'. It is caused by phlegm and toxin. It is located in Sanjiao,and its pathogenesis is essentially spleen deficiency and phlegm accumulation. Myeloma belongs to the category of ‘myeloma'.It is caused by blood stasis and toxin. It is located in bone marrow and related to kidney. Its pathogenesis is essentially kidney deficiency, blood stasis and toxin accumulation. Clinical treatment from toxin evil, fight poison, reconciliation detoxification,detoxication and engendering blood, played the total effect of strengthening the body resistance and eliminate pathogenic factors.
引文
[1]李达.常见血液病中医病名规范化探讨.现代中西医结合杂志,2009,18(10):1105-1107
[2]李达,杨淑莲,梁冰.中西医结合治疗急性非淋巴细胞白血病82例临床观察.山西中医,1995,11(6):20-21
[3]李达,代喜平,吴顺杰,等.中医序贯疗法辅助化疗治疗难治性急性髓系白血病疗效观察.深圳中西医结合杂志.2007,17(2):118-119
[4]李琤,胡永珍,李达.中西医结合治疗慢性粒单核细胞白血病临床分析.辽宁中医药大学学报.2013,15(6):198-200
[5]李达.秉承梁冰名老中医治疗多发性骨髓瘤经验进而探讨“肾虚血瘀”中医本质.第八届全国中西医结合血液病学术会议论文集,2007:220-224
[6]刘琨,李达,张宏业.87例多发性骨髓瘤的中医证型分析.新中医,2017,39(8):57-58
[7]代喜平,李达,梁冰.多发性骨髓瘤病因病机探微.浙江中西医结合杂志,2008,18(5):290-291,299
[8]李琤,李达.梁冰老中医诊治多发性骨髓瘤经验拾遗.中华中医药杂志,2013,28(7):2023-2025
[9]胡永珍,李达,韩凌.益肾活血饮逆转骨髓瘤凋亡抵抗的研究.深圳中西医结合杂志,2012,22(1):1-3,20
[10]胡永珍,李达.益肾活血饮配合亚砷酸治疗多发性骨髓瘤骨病的观察.辽宁中医杂志,2009,36(8):1331-1333
[11]胡永珍,李达.中西医结合治疗难治复发多发性骨髓瘤.浙江中西医结合杂志,2009,19(5):274-275
[12]李达,陈瑶.梁冰教授运用中成药巧治疑难血液病简介.新中医.2012,44(6):198-199
[13]胡琪祥.吴翰香教授治疗急性白血病经验.上海中医药杂志.2003,37(4):14-16
[14]胡晓梅,刘锋,麻柔,等.周霭祥运用青黄散治疗白血病经验.中医杂志,2011,52(14):1187-1189
[15]胡乃平,王展翔.周霭祥治疗白血病经验.中医杂志,2000,41(6):333-334
[16]周庆兵,胡晓梅.周霭祥教授治疗恶性血液病经验简介.新中医,2011,43(4):137-138
[17]周霭详.青黄散治疗白血病的研究.中国中西医结合杂志.1998,18(10):582-583
[18]张晨,黄世林,向阳,等,复方黄黛片诱导急性早幼粒细胞白血病细胞凋亡的研究.解放军医学杂志,2003,28(6):556-557
[19]向阳,黄世林,郭爱霞,等.复方黄黛片治疗急性早幼粒细胞白血病疗效分析.临床血液学杂志,2000,13(1):11-12
[20]周霭祥,姚宝森,郑金福,等.青黄散治疗慢性粒细胞白血病25例近期疗效观察.中西医结合杂志,1981,1(1):16-18
[21]刘锋,郭小青,胡晓梅,等.益髓青黄散治疗骨髓增生异常综合征36例.中医杂志,2011,52(3):241-242
[22]李达,陈瑶.“和法”方药辨治血液病经验.中医杂志,2012,53(15):1329-1330
[23]李琤,李达.“和法”方药在血液病治疗中的应用现状与展望.中华中医药杂志,2012,27(9):2378-2380
[2]李达,杨淑莲,梁冰.中西医结合治疗急性非淋巴细胞白血病82例临床观察.山西中医,1995,11(6):20-21
[3]李达,代喜平,吴顺杰,等.中医序贯疗法辅助化疗治疗难治性急性髓系白血病疗效观察.深圳中西医结合杂志.2007,17(2):118-119
[4]李琤,胡永珍,李达.中西医结合治疗慢性粒单核细胞白血病临床分析.辽宁中医药大学学报.2013,15(6):198-200
[5]李达.秉承梁冰名老中医治疗多发性骨髓瘤经验进而探讨“肾虚血瘀”中医本质.第八届全国中西医结合血液病学术会议论文集,2007:220-224
[6]刘琨,李达,张宏业.87例多发性骨髓瘤的中医证型分析.新中医,2017,39(8):57-58
[7]代喜平,李达,梁冰.多发性骨髓瘤病因病机探微.浙江中西医结合杂志,2008,18(5):290-291,299
[8]李琤,李达.梁冰老中医诊治多发性骨髓瘤经验拾遗.中华中医药杂志,2013,28(7):2023-2025
[9]胡永珍,李达,韩凌.益肾活血饮逆转骨髓瘤凋亡抵抗的研究.深圳中西医结合杂志,2012,22(1):1-3,20
[10]胡永珍,李达.益肾活血饮配合亚砷酸治疗多发性骨髓瘤骨病的观察.辽宁中医杂志,2009,36(8):1331-1333
[11]胡永珍,李达.中西医结合治疗难治复发多发性骨髓瘤.浙江中西医结合杂志,2009,19(5):274-275
[12]李达,陈瑶.梁冰教授运用中成药巧治疑难血液病简介.新中医.2012,44(6):198-199
[13]胡琪祥.吴翰香教授治疗急性白血病经验.上海中医药杂志.2003,37(4):14-16
[14]胡晓梅,刘锋,麻柔,等.周霭祥运用青黄散治疗白血病经验.中医杂志,2011,52(14):1187-1189
[15]胡乃平,王展翔.周霭祥治疗白血病经验.中医杂志,2000,41(6):333-334
[16]周庆兵,胡晓梅.周霭祥教授治疗恶性血液病经验简介.新中医,2011,43(4):137-138
[17]周霭详.青黄散治疗白血病的研究.中国中西医结合杂志.1998,18(10):582-583
[18]张晨,黄世林,向阳,等,复方黄黛片诱导急性早幼粒细胞白血病细胞凋亡的研究.解放军医学杂志,2003,28(6):556-557
[19]向阳,黄世林,郭爱霞,等.复方黄黛片治疗急性早幼粒细胞白血病疗效分析.临床血液学杂志,2000,13(1):11-12
[20]周霭祥,姚宝森,郑金福,等.青黄散治疗慢性粒细胞白血病25例近期疗效观察.中西医结合杂志,1981,1(1):16-18
[21]刘锋,郭小青,胡晓梅,等.益髓青黄散治疗骨髓增生异常综合征36例.中医杂志,2011,52(3):241-242
[22]李达,陈瑶.“和法”方药辨治血液病经验.中医杂志,2012,53(15):1329-1330
[23]李琤,李达.“和法”方药在血液病治疗中的应用现状与展望.中华中医药杂志,2012,27(9):2378-2380