美沙拉嗪联合双歧杆菌四联活菌片治疗溃疡性结肠炎临床研究
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摘要
目的:探讨溃疡性结肠炎患者采取美沙拉嗪联合双歧杆菌四联活菌进行治疗的临床效果以及相关表现。方法:对照组在常规治疗的基础上结合美沙拉嗪治疗,而观察组同时采取双歧杆菌四联活菌进行治疗。结果:观察组治疗效果以及痊愈人数明显优于对照组(P<0.05),两组用药后不良反应对比P>0.05。结论:溃疡性结肠炎患者经美沙拉嗪联合双歧杆菌四联活菌联合治疗具有良好的有效性、安全性。
Objective:To investigate the clinical effects ofmesalazine combined with bifidobacterium quadruple living bacterium in the treatment of ulcerative colitis.Methods:The control group was treated with mesalazine on the basis of routine treatment,while the observation group was treated with bifidobacterium quadruple living bacterium at the same time.Results:The effect of treatment and the numbers of healing in the observation group were obviously superior to those of the control group(P<0.05).The adverse reactions of the two groups were compared(P>0.05).Conclusion:The combination of mesalazine and bifidobacterium quadruple living bacteriumin the treatment of ulcerative colitis is of good efficiency and safety.
Objective:To investigate the clinical effects ofmesalazine combined with bifidobacterium quadruple living bacterium in the treatment of ulcerative colitis.Methods:The control group was treated with mesalazine on the basis of routine treatment,while the observation group was treated with bifidobacterium quadruple living bacterium at the same time.Results:The effect of treatment and the numbers of healing in the observation group were obviously superior to those of the control group(P<0.05).The adverse reactions of the two groups were compared(P>0.05).Conclusion:The combination of mesalazine and bifidobacterium quadruple living bacteriumin the treatment of ulcerative colitis is of good efficiency and safety.
引文
1王晓梅.枯草杆菌二联活菌肠溶胶囊、双歧杆菌乳杆菌三联活菌片联合美沙拉嗪治疗溃疡性结肠炎疗效分析.临床和实验医学杂志,2012,11(21):1697~1698.
2 彭玄杰.双歧杆菌三联活菌联合美沙拉嗪治疗溃疡性结肠炎的临床疗效分析.中国中西医结合消化杂志,2014,22(11):672~673.
3 韩李春,叶自亮,吕晓丹,等.美沙拉嗪联合双歧杆菌三联活菌散治疗溃疡性结肠炎临床疗效的Meta分析.广西医学,2017,39(8):1112~1118.
4 贺佳玉,何咏梅.美沙拉嗪联合双歧杆菌三联活菌治疗溃疡性结肠炎及对血清炎症因子的影响.四川医学,2015,6:854~857.
5 岳原亦,张强,林连捷,等.双歧杆菌四联活菌片联合美沙拉嗪对轻中度溃疡性结肠炎的疗效观察.实用药物与临床,2017,20(5):517~520.
6 陈伟,曹春宇,黎运呈,等.美沙拉嗪联合双歧杆菌三联活菌治疗溃疡性结肠炎患者的疗效分析.中国生化药物杂志,2017,37(3):90~91;94.
7 王友多,陈华.美沙拉嗪联合双歧杆菌四联活菌治疗活动期溃疡性结肠炎的临床观察.中国药房,2016,27(3):326~328.
8 易国栋,周翔禹,向兴朝,等.双歧杆菌三联活菌胶囊、复方谷氨酰胺肠溶胶囊联合美沙拉嗪对溃疡性结肠炎的疗效观察.临床消化病杂志,2017,29(3):139~143.
9 陈曦,夏兴洲,孙霞,等.双歧杆菌三联活菌联合美沙拉嗪治疗溃疡性结肠炎效果分析.中华全科医师杂志,2014,13(3):223~225.
2 彭玄杰.双歧杆菌三联活菌联合美沙拉嗪治疗溃疡性结肠炎的临床疗效分析.中国中西医结合消化杂志,2014,22(11):672~673.
3 韩李春,叶自亮,吕晓丹,等.美沙拉嗪联合双歧杆菌三联活菌散治疗溃疡性结肠炎临床疗效的Meta分析.广西医学,2017,39(8):1112~1118.
4 贺佳玉,何咏梅.美沙拉嗪联合双歧杆菌三联活菌治疗溃疡性结肠炎及对血清炎症因子的影响.四川医学,2015,6:854~857.
5 岳原亦,张强,林连捷,等.双歧杆菌四联活菌片联合美沙拉嗪对轻中度溃疡性结肠炎的疗效观察.实用药物与临床,2017,20(5):517~520.
6 陈伟,曹春宇,黎运呈,等.美沙拉嗪联合双歧杆菌三联活菌治疗溃疡性结肠炎患者的疗效分析.中国生化药物杂志,2017,37(3):90~91;94.
7 王友多,陈华.美沙拉嗪联合双歧杆菌四联活菌治疗活动期溃疡性结肠炎的临床观察.中国药房,2016,27(3):326~328.
8 易国栋,周翔禹,向兴朝,等.双歧杆菌三联活菌胶囊、复方谷氨酰胺肠溶胶囊联合美沙拉嗪对溃疡性结肠炎的疗效观察.临床消化病杂志,2017,29(3):139~143.
9 陈曦,夏兴洲,孙霞,等.双歧杆菌三联活菌联合美沙拉嗪治疗溃疡性结肠炎效果分析.中华全科医师杂志,2014,13(3):223~225.