阿奇霉素不同给药方式治疗急性肠炎的疗效及安全性对比分析
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摘要
为探讨阿奇霉素不同给药方式治疗急性肠炎的临床效果,将2016年8月至2017年11月我院收治的92例急性肠炎患者随机分为对照组和试验组,各46例,对照组治疗全程采用阿奇霉素静脉滴注,试验组采用阿奇霉素静脉滴注加口服的方式治疗,对比2组治疗效果。结果显示,试验组总有效率为93.47%(43/46),对照组为89.13%(41/46),2组比较差异无统计学意义,P>0.05。试验组不良反应发生率(6.52%, 3/46)明显低于对照组(23.91%.11/46), P <0.05。结果表明,阿奇霉素静脉滴注联合口服治疗急性肠炎的临床疗效肯定,不良反应少,临床推广价值高。
To investigate the clinical effect of different medication patterns of Azithromycin for acute enteronitis(AE),92 AE patients admitted in author's hospital(2016-08 —2017-11) were randomly divided into control group( n =46, whole course intravenously injecting Azithromycin) and trial one( n =46, intravenously + orally administered Azithromycin),both groups' effect were compared. As results,in total effective rate there was no statistical difference[93.47 %(43/46) vs 89.13 %(41/46),P> 0.05],but in untoward reaction incidence trial group was significantly lower than control one[(6.52 %,3/46) vs(23.91%(11/46),P <0. 05]. Results show that orally plus intravenously administering Azithromycin for AE has certain effect,less untoward reaction,which has high clinical popularization value.
To investigate the clinical effect of different medication patterns of Azithromycin for acute enteronitis(AE),92 AE patients admitted in author's hospital(2016-08 —2017-11) were randomly divided into control group( n =46, whole course intravenously injecting Azithromycin) and trial one( n =46, intravenously + orally administered Azithromycin),both groups' effect were compared. As results,in total effective rate there was no statistical difference[93.47 %(43/46) vs 89.13 %(41/46),P> 0.05],but in untoward reaction incidence trial group was significantly lower than control one[(6.52 %,3/46) vs(23.91%(11/46),P <0. 05]. Results show that orally plus intravenously administering Azithromycin for AE has certain effect,less untoward reaction,which has high clinical popularization value.
引文
[1]郭玉钢.阿奇霉素不同方式治疗急性肠炎的疗效及安全性对比[J].北方药学,2018,15(4):155.
[2]王静.观察阿奇霉素治疗急性肠炎的疗效及安全性[J].中国保健营养(下旬刊),2012(10):4000-4001.
[3]牟来旭.观察阿奇霉素治疗急性肠炎的疗效及安全性[J].医学信息,2016,29(9):330.
[4]赵桂芳.应用阿奇霉素治疗急性肠炎的疗效及安全性[J].求医问药(下半月刊),2013(7):302.
[5]汪伟.急性肠炎治疗中阿奇霉素合理应用的临床疗效分析[J].中国保健营养,2017,27(13):124-125.
[6]周有际.阿奇霉素在治疗急性肠炎中的应用价值[J].吉林医学,2015(16):3577-3578.
[2]王静.观察阿奇霉素治疗急性肠炎的疗效及安全性[J].中国保健营养(下旬刊),2012(10):4000-4001.
[3]牟来旭.观察阿奇霉素治疗急性肠炎的疗效及安全性[J].医学信息,2016,29(9):330.
[4]赵桂芳.应用阿奇霉素治疗急性肠炎的疗效及安全性[J].求医问药(下半月刊),2013(7):302.
[5]汪伟.急性肠炎治疗中阿奇霉素合理应用的临床疗效分析[J].中国保健营养,2017,27(13):124-125.
[6]周有际.阿奇霉素在治疗急性肠炎中的应用价值[J].吉林医学,2015(16):3577-3578.