雷尼替丁与奥美拉唑治疗消化系统溃疡的效果对比
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摘要
目的分析并对比雷尼替丁与奥美拉唑治疗消化系统溃疡的效果。方法选取2017年6月~2018年6月我院收治的90例消化系统溃疡患者作为研究对象,依据随机数字表法将其分为对照组(45例)与观察组(45例)。对照组患者给予雷尼替丁治疗,观察组患者给予奥美拉唑治疗。观察并比较两组患者的治疗总有效率及不良反应发生情况。结果观察组患者的总有效率(97.78%)高于对照组(84.44%),差异有统计学意义(P<0.05)。观察组患者的不良反应总发生率为17.78%,低于对照组的37.78%,差异有统计学意义(P<0.05)。结论与雷尼替丁相比,奥美拉唑治疗消化系统溃疡的效果更显著。
Objective To analyze and compare the effect of Ranitidine and Omeprazole in the treatment of peptic ulcer.Methods A total of 90 patients with peptic ulcer from June 2017 to June 2018 in our hospital were selected as the research objects. According to the random number table method, they were divided into the control group(45 cases) and the observation group(45 cases). The control group was treated with Ranitidine, and the observation group was treated with Omeprazole. The total effective rate and adverse reactions were observed and compared between the two groups.Results The total effective rate of the observation group was 97.78%, which was higher than that of the control group(84.44%), with significant difference(P<0.05). The total incidence of adverse reactions in the observation group was17.78%, which was significantly lower than that in the control group accounting for 37.78%, with significant difference(P<0.05). Conclusion Omeprazole is more effective than Ranitidine in the treatment of peptic ulcer.
Objective To analyze and compare the effect of Ranitidine and Omeprazole in the treatment of peptic ulcer.Methods A total of 90 patients with peptic ulcer from June 2017 to June 2018 in our hospital were selected as the research objects. According to the random number table method, they were divided into the control group(45 cases) and the observation group(45 cases). The control group was treated with Ranitidine, and the observation group was treated with Omeprazole. The total effective rate and adverse reactions were observed and compared between the two groups.Results The total effective rate of the observation group was 97.78%, which was higher than that of the control group(84.44%), with significant difference(P<0.05). The total incidence of adverse reactions in the observation group was17.78%, which was significantly lower than that in the control group accounting for 37.78%, with significant difference(P<0.05). Conclusion Omeprazole is more effective than Ranitidine in the treatment of peptic ulcer.
引文
[1]张丽华.雷尼替丁联合奥美拉唑治疗消化性溃疡的临床研究[J].中国卫生标准管理,2015,6(29):98-99.
[2]鲁天瑜,龚梅金,郑义.奥美拉唑与雷尼替丁治疗胃溃疡的效果比较[J].中国当代医药,2018,25(17):140-142.
[3]李坤,杜永哲,杨子京.奥美拉唑与雷尼替丁联合治疗Hp阳性消化性溃疡的临床疗效观察[J].中国卫生标准管理,2016,7(17):110-111.
[4]刘园园,周梦颖,艾佳佳.奥美拉唑药理作用及其临床应用的研究[J].饮食保健,2018,15(2):83-84.
[5]刘小明.奥美拉唑与雷尼替丁治疗胃食管反流病的疗效比较研究[J].临床合理用药杂志,2017,10(27):17,19.
[6]孙晓春.雷尼替丁联合奥美拉唑治疗消化性溃疡的临床研究[J].中国卫生标准管理,2015,6(11):48-49.
[7]康成才.雷尼替丁和奥美拉唑治疗浅表性胃炎的效果对比[J].大家健康,2017,33(8):144.
[8]赵思军.奥美拉唑与雷尼替丁治疗消化性溃疡临床效果对比[J].心理医生,2017,23(28):345-346.
[9]曹志林.浅表胃炎患者接受雷尼替丁奥美拉唑治疗的价值分析[J].健康大视野,2018,26(6):216.
[10]王慧梅.奥美拉唑与雷尼替丁治疗慢性胃炎合并消化性溃疡的疗效对比[J].临床医学研究与实践,2016,1(24):78-79.
[11]侯惠英,蒋艳玲,高振杰.不同药物(雷尼替丁、奥美拉唑)对浅表性胃炎的疗效对比[J].临床医药文献电子杂志,2017,4(21):4115-4116.
[12]高卫仁.雷尼替丁和奥美拉唑治疗浅表性胃炎的临床效果比较[J].河南医学研究,2018,27(1):60-61.
[13]李斌.比较雷尼替丁、奥美拉唑治疗浅表性胃炎效果[J].饮食保健,2018,15(8):79-80.
[14]谭张龙.咪唑斯汀与雷尼替丁联用治疗慢性特发性荨麻疹疗效与不良反应探究[J].中外医疗,2017,37(13):148-149,152.
[15]顾永红.泮托拉唑、雷尼替丁治疗十二指肠溃疡药物经济学对比研究[J].临床医学研究与实践,2017,2(20):35-36.
[16]梁慧颖.分析奥美拉唑药物所致不良反应及其与其他药物之间的相互作用[J].中国现代药物应用,2015,9(20):104-105.
[17]王丽嵘,杨治国.分析奥美拉唑药物所致的不良反应及其与其他药物的相互作用[J].中国医疗器械信息,2015,21(3Z):316.
[18]罗君,王军.雷尼替丁与次枸橼酸铋钾联合治疗小儿消化性溃疡的效果观察[J].中南医学科学杂志,2017,45(4):408-411.
[2]鲁天瑜,龚梅金,郑义.奥美拉唑与雷尼替丁治疗胃溃疡的效果比较[J].中国当代医药,2018,25(17):140-142.
[3]李坤,杜永哲,杨子京.奥美拉唑与雷尼替丁联合治疗Hp阳性消化性溃疡的临床疗效观察[J].中国卫生标准管理,2016,7(17):110-111.
[4]刘园园,周梦颖,艾佳佳.奥美拉唑药理作用及其临床应用的研究[J].饮食保健,2018,15(2):83-84.
[5]刘小明.奥美拉唑与雷尼替丁治疗胃食管反流病的疗效比较研究[J].临床合理用药杂志,2017,10(27):17,19.
[6]孙晓春.雷尼替丁联合奥美拉唑治疗消化性溃疡的临床研究[J].中国卫生标准管理,2015,6(11):48-49.
[7]康成才.雷尼替丁和奥美拉唑治疗浅表性胃炎的效果对比[J].大家健康,2017,33(8):144.
[8]赵思军.奥美拉唑与雷尼替丁治疗消化性溃疡临床效果对比[J].心理医生,2017,23(28):345-346.
[9]曹志林.浅表胃炎患者接受雷尼替丁奥美拉唑治疗的价值分析[J].健康大视野,2018,26(6):216.
[10]王慧梅.奥美拉唑与雷尼替丁治疗慢性胃炎合并消化性溃疡的疗效对比[J].临床医学研究与实践,2016,1(24):78-79.
[11]侯惠英,蒋艳玲,高振杰.不同药物(雷尼替丁、奥美拉唑)对浅表性胃炎的疗效对比[J].临床医药文献电子杂志,2017,4(21):4115-4116.
[12]高卫仁.雷尼替丁和奥美拉唑治疗浅表性胃炎的临床效果比较[J].河南医学研究,2018,27(1):60-61.
[13]李斌.比较雷尼替丁、奥美拉唑治疗浅表性胃炎效果[J].饮食保健,2018,15(8):79-80.
[14]谭张龙.咪唑斯汀与雷尼替丁联用治疗慢性特发性荨麻疹疗效与不良反应探究[J].中外医疗,2017,37(13):148-149,152.
[15]顾永红.泮托拉唑、雷尼替丁治疗十二指肠溃疡药物经济学对比研究[J].临床医学研究与实践,2017,2(20):35-36.
[16]梁慧颖.分析奥美拉唑药物所致不良反应及其与其他药物之间的相互作用[J].中国现代药物应用,2015,9(20):104-105.
[17]王丽嵘,杨治国.分析奥美拉唑药物所致的不良反应及其与其他药物的相互作用[J].中国医疗器械信息,2015,21(3Z):316.
[18]罗君,王军.雷尼替丁与次枸橼酸铋钾联合治疗小儿消化性溃疡的效果观察[J].中南医学科学杂志,2017,45(4):408-411.