银屑病合并肾损害11例临床和病理分析
摘要
<正>银屑病又称牛皮癣,是一种免疫介导的的慢性炎症性疾病,除皮肤损害以外,还容易合并心血管疾病、高血压、糖尿病、血脂异常、贫血、代谢综合征和肾损伤。目前普遍认为,银屑病是多基因遗传背景下、多环境因素刺激诱导的T细胞为主的细胞免疫功能紊乱的免疫性疾病~([1])。银屑病与肾脏疾病之间是否存在相关性尚不清楚。最近有荟萃分析显示,银屑
引文
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[5]Michalek IM,Loring B,John SM.A systematic review of worldwide epidemiology of psoriasis[J].J Eur Acad Dermatol Venereol,2017,31(2):205-212.
[6]Menter A,Griffiths CE,Tebbey PW,et al.International Psoriasis Council.Exploring the association between cardiovascular and other disease-related risk factors in the psoriasis population:the need for increased understanding across the medical community[J].J Eur Acad Dermatol Venereol,2010,24:1371-1377.
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[8]Chang CF,Lin CC,Chen JY.Lipoprotein glomerulopathy associated with psoriasis vulgaris:report of 2 cases with apolipoprotein E3/3[J].Am J Kidney Dis,2003,42(3):E18-23.
[9]Kamshima T,Hachisuka H.FKS06 and cyeiosporin A inhi-bit growth factor-stimulated human keratinocyte proliferation by blocking cells in the GO/G1 phases of the cell cycle[J].J Dermatol Sei,1996,12(3):246-254.
[10]Paneni F,Osto E,Costantino S,et al.Deletion of the activated protein-1 transcription factor JunD induces oxidative stress and accelerates age-related endothelial dysfunction[J].Circulation,2013,127:1229-1240.
[11]Cassano N,Vestita M,Panaro M,et al.Renal function in psoriasis patients[J].Eur J Dermatol,2011,21:264-265.
[12]Chiu HY,Huang HL,Li CH,et al.Increased risk of glomerulonephritis and chronic kidney disease in relation to the severity of Clin Rheumatol,2016,35:297-302 301psoriasis,concomitant medication,and comorbidity:a nationwide population-based cohort study[J].Br J Dermatol,2015,173(1):146-154.
[13]Hall RP,Peck GL,Lawley TJ.Circulating IgA immune com-plexes in patients with psoriasis[J].J Investig Dermatol,1983,80:465-468.
[14]Lindqvist U,Rudsander A,Bostrm A,et al.IgA antibodies to gliadin and coeliac disease in psoriaticar thritis[J].Rheumatology,2002,41:31-37.
[15]Lee MR,Cooper AJ.Biologic agents in psoriasis[J].Australas JDermatol,2006,47:217-229.
[16]Melgao SS,Silva GB Jr,Dantas AM,et al.Evaluation of renal function in patients with psoriasis using immunobiologicals[J].An Bras Dermatol,2013,88:667-669.
[17]Yahya TM,Dhanyamraju S,Harrington TM,et al.Spontaneous resolution of lupus nephritis following withdrawal of etanercept[J].Ann Clin Lab Sci,2013,43:447-449.
[18]MenèP,Franeta AJ,Conti G,et al.Extracapillary glomerulonephritis during etanercept treatment for juvenile psoriatic arthritis[J].Clin Exp Rheumatol,2010,28:91-93.
[19]Davidovici BB,Sattar N,Prinz J,et al.Psoriasis and systemic inflammatory diseases:potential mechanistic links between skin disease and comorbiol conditions[J].Invest Dermatol,2010,130:1785-1796.