妇科千金片治疗盆腔炎的文献特征分析
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摘要
目的:通过文献挖掘分析妇科千金片治疗盆腔炎的研究现状。方法:从中国知网数据库检索关键词"妇科千金片""盆腔炎",纳入篇名为"妇科千金片治疗盆腔炎"的全部文献,从文献的年度分布、发表类型、学科分布、基金类型及作者单位、研究类型等方面分析妇科千金片治疗盆腔炎的研究现状。结果:共检索到相关文献123篇,近5年文献数量显著增加。文献以期刊论文为主,占93.5%。从学科分布来看,妇产科学,占38.52%;其次是中医学,占33.33%;中药学排在第三位,占18.52%。研究机构主要集中在湖南中医药大学和湖南省株洲千金药业股份有限公司,基金资助比较少。研究类型以临床观察为主,占73.2%,其次是动物实验,占19.5%。研究地域主要是湖南、四川、江西三省。结论:妇科千金片治疗盆腔炎的研究已有近20年的历史,呈逐年增长趋势,以临床研究为主,大样本、多中心的报道比较欠缺,有关药理机制的研究较少,药物有效成分及作用靶点尚未明确,需要科研工作者进一步深入探讨。
Objective:To analyze research statues of FuKe Qianjin tablets in the treatment for pelvic inflammation by literature mining. Methods: Key words "FuKe QianJin tablets" and "pelvic inflammation" were retrieved from CNKI, all the papers named FuKe Qianjin tablets in treating pelvic inflammation were included,research status was analyzes from the aspects: annual distribution of the papers, publication types, the distribution of the subjects, fund types, author units, research types and others. Results: All 123 papers had been found, the numbers of the papers in the recent five years were increasing notably. Most of the literature were periodical papers and they occupied 93.5%. The papers were about the study of gynecology, and they held 38.52%; the next were TCM and33.33%; the third place was the science of Chinese materia medica and 18.52%. Research institutes were Hunan University of Chinese Medicine and Hunan provincial Zhuzhou Qianjin Pharmacy mainly, the funds were fewer.Research types were clinical observation mostly and held 73.2%, the next were animal experiments and 19.5%.Research fields covered Hunan, Chengdu and Jiangxi provinces. Conclusion: Researches on FuKe Qianjin tablets in treating pelvic inflammation have been performed around 20 years, and it shows the increasing tendency year by year. Since most of the researches are about clinical study, lacking large-sample, multicenter reports, fewer studies about pharmacological mechanism, uncertain active ingredients and potential targets of the drugs, they need to be further discussed.
Objective:To analyze research statues of FuKe Qianjin tablets in the treatment for pelvic inflammation by literature mining. Methods: Key words "FuKe QianJin tablets" and "pelvic inflammation" were retrieved from CNKI, all the papers named FuKe Qianjin tablets in treating pelvic inflammation were included,research status was analyzes from the aspects: annual distribution of the papers, publication types, the distribution of the subjects, fund types, author units, research types and others. Results: All 123 papers had been found, the numbers of the papers in the recent five years were increasing notably. Most of the literature were periodical papers and they occupied 93.5%. The papers were about the study of gynecology, and they held 38.52%; the next were TCM and33.33%; the third place was the science of Chinese materia medica and 18.52%. Research institutes were Hunan University of Chinese Medicine and Hunan provincial Zhuzhou Qianjin Pharmacy mainly, the funds were fewer.Research types were clinical observation mostly and held 73.2%, the next were animal experiments and 19.5%.Research fields covered Hunan, Chengdu and Jiangxi provinces. Conclusion: Researches on FuKe Qianjin tablets in treating pelvic inflammation have been performed around 20 years, and it shows the increasing tendency year by year. Since most of the researches are about clinical study, lacking large-sample, multicenter reports, fewer studies about pharmacological mechanism, uncertain active ingredients and potential targets of the drugs, they need to be further discussed.
引文
[1]刘丽,陈小丽,魏歆然,等.妇科千金片治疗慢性盆腔炎的研究进展[J].光明中医,2016,31(12):1837-1839.
[2]朴香淑,孙艳茹,屈慧启,等.金刚藤联合妇科千金片治疗慢性盆腔炎的疗效及对血清细胞因子的影响[J].河北医药,2017,39(15):2356-2358.
[3]向燕,文峰,杨秀英.金刚藤胶囊联合妇科千金片治疗对慢性盆腔炎患者血清炎性因子、免疫功能及血液流变学指标的影响[J].海南医学院学报,2017,23(13):1819-1821.
[4]赵静,郭端英,刘阳.左氧氟沙星联合妇科千金片对慢性盆腔炎患者炎性因子的影响[J].中国实用医药,2017,12(5):113-115.
[5]张新艳.妇科千金片联合左氧氟沙星、甲硝唑对盆腔炎的临床疗效[J].实用妇科内分泌杂志:电子版,2017,4(4):115-117.
[6]李维,邹亮,龚云,等.妇科千金片对阿奇霉素在慢性盆腔炎大鼠体内药物动力学的影响[J].中国中药杂志,2016,41(12):2339-2343.
[7]张福梅.金刚藤联合妇科千金片对慢性盆腔炎的疗效及其对患者血清细胞因子IL-6和GM-CSF水平的影响[J].中国妇幼保健,2016,31(13):2606-2608.
[8]雷桂兰,汪有新.妇科千金片联合少腹逐瘀颗粒治疗急性盆腔炎临床研究[J].河南中医,2015,35(11):2811-2813.
[9]付健.花红片、妇科千金片治疗慢性盆腔炎180例三中心临床观察[J].中国继续医学教育,2015,7(25):207-208.
[10]代敬兰.妇科千金片联合抗生素治疗慢性盆腔炎临床观察[J].实用中西医结合临床,2014,14(3):55-57.
[11]池小仙,李海霞.妇科千金片联合胜红清热胶囊治疗急性盆腔炎[J].辽宁中医杂志,2013,40(11):2263-2264.
[12]袁建菱,李萍,文琦琪,等.妇科千金片对盆腔炎大鼠TLR2/4-NF-κB信号通路影响的研究[J].湖南中医药大学学报,2016,36(11):13-17.
[13]李维,邹亮,龚云,等.妇科千金片对阿奇霉素在慢性盆腔炎大鼠体内药物动力学的影响[J].中国中药杂志,2016,41(12):2339-2343.
[14]闫娟,李岗.低频超声联合妇科千金片对慢性盆腔炎模型大鼠TNF-α、IL-6及IL-2水平的影响[J].河南中医,2015,35(9):2049-2051.
[15]段丹梅.妇科千金片对慢性盆腔炎模型大鼠TNF-α、IL-2、IL-6表达的影响[J].中医学报,2014,29(10):1467-1468.
[16]聂晶,李鑫,师振予,等.妇科千金片对慢性盆腔炎模型大鼠卵巢组织caspase-3和caspase-8表达的影响[J].西北药学杂志,2014,29(4):385-387.
[17]袁建菱,郭建生,左之文,等.妇科千金片对盆腔炎模型大鼠血清中TNF-α、NF-κB含量的影响[J].中国中医药现代远程教育,2014,12(7):150-151.
[18]李鑫,郭建生,师振予,等.妇科千金片对慢性盆腔炎大鼠血清炎性细胞因子表达的影响[J].中国实验方剂学杂志,2013,19(10):225-228.
[19]袁建菱,郭建生,左之文,等.妇科千金片对盆腔炎模型大鼠血清中IL-2、IL-6、IL-8含量的影响[J].中华中医药杂志,2013,28(1):250-252.
[20]袁建菱,郭建生,左之文,等.妇科千金片对盆腔炎大鼠子宫、卵巢、输卵管Caspase-3表达的影响[J].湖南中医药大学学报,2012,32(12):58-60.
[2]朴香淑,孙艳茹,屈慧启,等.金刚藤联合妇科千金片治疗慢性盆腔炎的疗效及对血清细胞因子的影响[J].河北医药,2017,39(15):2356-2358.
[3]向燕,文峰,杨秀英.金刚藤胶囊联合妇科千金片治疗对慢性盆腔炎患者血清炎性因子、免疫功能及血液流变学指标的影响[J].海南医学院学报,2017,23(13):1819-1821.
[4]赵静,郭端英,刘阳.左氧氟沙星联合妇科千金片对慢性盆腔炎患者炎性因子的影响[J].中国实用医药,2017,12(5):113-115.
[5]张新艳.妇科千金片联合左氧氟沙星、甲硝唑对盆腔炎的临床疗效[J].实用妇科内分泌杂志:电子版,2017,4(4):115-117.
[6]李维,邹亮,龚云,等.妇科千金片对阿奇霉素在慢性盆腔炎大鼠体内药物动力学的影响[J].中国中药杂志,2016,41(12):2339-2343.
[7]张福梅.金刚藤联合妇科千金片对慢性盆腔炎的疗效及其对患者血清细胞因子IL-6和GM-CSF水平的影响[J].中国妇幼保健,2016,31(13):2606-2608.
[8]雷桂兰,汪有新.妇科千金片联合少腹逐瘀颗粒治疗急性盆腔炎临床研究[J].河南中医,2015,35(11):2811-2813.
[9]付健.花红片、妇科千金片治疗慢性盆腔炎180例三中心临床观察[J].中国继续医学教育,2015,7(25):207-208.
[10]代敬兰.妇科千金片联合抗生素治疗慢性盆腔炎临床观察[J].实用中西医结合临床,2014,14(3):55-57.
[11]池小仙,李海霞.妇科千金片联合胜红清热胶囊治疗急性盆腔炎[J].辽宁中医杂志,2013,40(11):2263-2264.
[12]袁建菱,李萍,文琦琪,等.妇科千金片对盆腔炎大鼠TLR2/4-NF-κB信号通路影响的研究[J].湖南中医药大学学报,2016,36(11):13-17.
[13]李维,邹亮,龚云,等.妇科千金片对阿奇霉素在慢性盆腔炎大鼠体内药物动力学的影响[J].中国中药杂志,2016,41(12):2339-2343.
[14]闫娟,李岗.低频超声联合妇科千金片对慢性盆腔炎模型大鼠TNF-α、IL-6及IL-2水平的影响[J].河南中医,2015,35(9):2049-2051.
[15]段丹梅.妇科千金片对慢性盆腔炎模型大鼠TNF-α、IL-2、IL-6表达的影响[J].中医学报,2014,29(10):1467-1468.
[16]聂晶,李鑫,师振予,等.妇科千金片对慢性盆腔炎模型大鼠卵巢组织caspase-3和caspase-8表达的影响[J].西北药学杂志,2014,29(4):385-387.
[17]袁建菱,郭建生,左之文,等.妇科千金片对盆腔炎模型大鼠血清中TNF-α、NF-κB含量的影响[J].中国中医药现代远程教育,2014,12(7):150-151.
[18]李鑫,郭建生,师振予,等.妇科千金片对慢性盆腔炎大鼠血清炎性细胞因子表达的影响[J].中国实验方剂学杂志,2013,19(10):225-228.
[19]袁建菱,郭建生,左之文,等.妇科千金片对盆腔炎模型大鼠血清中IL-2、IL-6、IL-8含量的影响[J].中华中医药杂志,2013,28(1):250-252.
[20]袁建菱,郭建生,左之文,等.妇科千金片对盆腔炎大鼠子宫、卵巢、输卵管Caspase-3表达的影响[J].湖南中医药大学学报,2012,32(12):58-60.