乳腺导管灌注联合三才疗法治疗早期急性乳腺炎的效果分析
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摘要
目的:研究早期急性乳腺炎患者采取乳腺导管灌注结合三才疗法治疗的临床效果。方法:选择2016年1月-2017年10月本院乳腺科收治的早期急性乳腺炎患者66例作为研究对象,按照不同的治疗方式将其分为观察组(n=34)与对照组(n=32)。观察组在手法按摩排乳基础上采取乳腺导管灌注结合三才疗法治疗,对照组采取静脉滴注抗生素结合手法按摩排乳治疗,比较两组的治疗效果以及治疗前后的体温、疼痛和相关指标变化情况。结果:观察组总有效率为94.12%,明显高于对照组的75.00%,差异有统计学意义(X~2=14.000,P=0.000)。治疗前两组的体温及疼痛评分变化情况比较,差异均无统计学意义(P>0.05);治疗后,观察组的体温及疼痛评分变化情况均明显低于对照组,差异均有统计学意义(t=3.227、6.061,P=0.002、0.000)。治疗前两组各项指标比较,差异均无统计学意义(P>0.05);治疗后,观察组中性粒细胞比值明显高于对照组,超敏C反应蛋白水平明显低于对照组,差异均有统计学意义(P<0.05)。结论:早期急性乳腺炎患者采取乳腺导管灌注联合三才疗法治疗效果显著,明显改善患者相关症状,有效缓解炎症以及疼痛感,促进肿块消退,具有推广及应用价值。
Objective:To study the clinical effect of mammary catheter perfusion and triple therapy in the treatment of early stage of acute mastitis.Method:A total of 66 patients with early stage of acute mastitis treated from January 2016 to October 2017 in breast surgery of our hospital were selected as the study objects.According to different treatment methods,they were divided into observation group(n=34) and control group(n=32).The observation group was treated with mammary catheter perfusion combined with triple therapy on the basis of manual massage,the control group was treated with intravenous drip of antibiotics combined with manual massage.The therapeutic effect and the changes of body temperature,pain scores and related indicators before and after treatment were compared between the two groups.Result:The total effective rate of the observation group was 94.12%,which was significantly higher than 75.00% of the control group,the difference was statistically significant(X~2=14.000,P=0.000).There were no significant differences in the changes of body temperature and pain score between the two groups before treatment(P>0.05).After treatment,the changes of body temperature and pain score in the observation group were significantly lower than those in the control group,the differences were statistically significant(t=3.227,6.061;P=0.002,0.000).There were no significant differences in the related indexes between the two groups before treatment(P>0.05).After treatment,the ratio of neutrophile granulocyte in the observation group was significantly higher than that in the control group,the level of hypersensitive C-reactive protein was significantly lower than that in the control group,the differences were statistically significant(P<0.05).Conclusion:The mammary catheter perfusion and triple therapy has an obvious effect in patients with early stage of acute mastitis,can significantly improve the clinical symptoms,relieve the inflammation conditions and pain degree and promote the regression of the mass,has the value of promotion and application.
Objective:To study the clinical effect of mammary catheter perfusion and triple therapy in the treatment of early stage of acute mastitis.Method:A total of 66 patients with early stage of acute mastitis treated from January 2016 to October 2017 in breast surgery of our hospital were selected as the study objects.According to different treatment methods,they were divided into observation group(n=34) and control group(n=32).The observation group was treated with mammary catheter perfusion combined with triple therapy on the basis of manual massage,the control group was treated with intravenous drip of antibiotics combined with manual massage.The therapeutic effect and the changes of body temperature,pain scores and related indicators before and after treatment were compared between the two groups.Result:The total effective rate of the observation group was 94.12%,which was significantly higher than 75.00% of the control group,the difference was statistically significant(X~2=14.000,P=0.000).There were no significant differences in the changes of body temperature and pain score between the two groups before treatment(P>0.05).After treatment,the changes of body temperature and pain score in the observation group were significantly lower than those in the control group,the differences were statistically significant(t=3.227,6.061;P=0.002,0.000).There were no significant differences in the related indexes between the two groups before treatment(P>0.05).After treatment,the ratio of neutrophile granulocyte in the observation group was significantly higher than that in the control group,the level of hypersensitive C-reactive protein was significantly lower than that in the control group,the differences were statistically significant(P<0.05).Conclusion:The mammary catheter perfusion and triple therapy has an obvious effect in patients with early stage of acute mastitis,can significantly improve the clinical symptoms,relieve the inflammation conditions and pain degree and promote the regression of the mass,has the value of promotion and application.
引文
[1]刘洁,蒋燕.早期急性乳腺炎综合护理干预的疗效观察[J].中国医药科学,2013,3(18):140-141.
[2]蔡珍玉,姚磊,王菁,等.乳腺浸润性导管癌与导管内癌Ki-67、C-erb B-2表达与超声造影表现的关系[J].中华超声影像学杂志,2014,23(12):1061-1064.
[3]栾金红,尹志伟,祝艳菊,等.中药灌注治疗炎性乳腺导管扩张症的疗效观察[J].中国中西医结合影像学杂志,2015,3(3):331-333.
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[9]毕燕玲,陈汉红.健康人血白细胞中性粒细胞、淋巴细胞比值潜在的变化[J].广东药学院学报,2003,19(4):372-372,376.
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[12]李丽,赵海军,徐瑾,等.中医结合治疗急性乳腺炎疗效观察[J].现代中西医结合杂志,2014,23(1):69-71.
[13]吴丽萍,史丹红,肖淑珠,等.产后康复仪与手法乳房按摩对促进母乳喂养的疗效比较[J].中国校医,2017,31(1):64-65.
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[16]池华茂,彭金娟,杨卉,等.纤维乳管镜在乳腺导管炎性疾病中的应用[J/OL].中华乳腺病杂志(电子版),2013,7(3):14,19.
[17]沈叶,虞贞凤,单远洲,等.纤维乳腺导管镜在乳头溢液疾病诊治中的应用[J].南昌大学学报(医学版),2014,54(2):63-65.
[18]刘明星,吕红发,张金鹏,等.羊乳腺炎乳腺导管及腺泡铸型[J].解剖学报,2017,48(6):721-725.
[19]高海凤,马祥君,汪洁等.乳腺导管探查术治疗乳汁淤积的效果[J/OL].中华乳腺病杂志(电子版),2013,7(3):36-39.
[20]程涓,丁华野,杜玉堂等.肉芽肿性小叶性乳腺炎伴发乳腺导管扩张症的临床病理学观察[J].中华病理学杂志,2013,42(10):665-668.
[21]黄汉源.浆细胞性乳腺炎外科治疗进展:整形外科技术的应用[J/OL].中华乳腺病杂志(电子版),2013,7(3):52-54.
[2]蔡珍玉,姚磊,王菁,等.乳腺浸润性导管癌与导管内癌Ki-67、C-erb B-2表达与超声造影表现的关系[J].中华超声影像学杂志,2014,23(12):1061-1064.
[3]栾金红,尹志伟,祝艳菊,等.中药灌注治疗炎性乳腺导管扩张症的疗效观察[J].中国中西医结合影像学杂志,2015,3(3):331-333.
[4]曾莉,郁进,宫悦,等.乳腺导管扩张症的造影诊断及介入性药物灌注治疗[J].现代医用影像学,2016,25(4):682-684,690.
[5]Markiewicz E,Fan X,Mustafi D,et al.High resolution 3D MRI of mouse mammary glands with intra-ductal injection of contrast media[J].Magnetic Resonance Imaging,2015,33(1):161-165.
[6]王永悦,吕钢,闵捷,等.吕氏三联疗法治疗早期急性乳腺炎临床观察[J].中国中医急症,2015,24(4):693-695.
[7]胡志花.早期急性乳腺炎的综合护理干预及疗效观察[J].中国现代药物应用,2014,8(7):201.
[8]李淑妮,蔡容燕,蔡婉静,等.孕期乳头护理在预防孕产妇产后乳腺炎中的效果[J].西部医学,2017,29(11):1608-1610.
[9]毕燕玲,陈汉红.健康人血白细胞中性粒细胞、淋巴细胞比值潜在的变化[J].广东药学院学报,2003,19(4):372-372,376.
[10]王炜红.中西医结合疗法治疗急性乳腺炎疗效研究[J/OL].中西医结合心血管病电子杂志,2015,3(5):12-13.
[11]李燕.早期急性乳腺炎的综合护理效果观察[J].临床合理用药杂志,2013,6(6):118.
[12]李丽,赵海军,徐瑾,等.中医结合治疗急性乳腺炎疗效观察[J].现代中西医结合杂志,2014,23(1):69-71.
[13]吴丽萍,史丹红,肖淑珠,等.产后康复仪与手法乳房按摩对促进母乳喂养的疗效比较[J].中国校医,2017,31(1):64-65.
[14]高援.推拿点穴排乳配合中药治疗急性乳腺炎90例疗效探讨[J].中国实用医药,2014,9(2):232-233.
[15]纪元英,韦桂依.乳腺导管灌注联合三才疗法治疗乳腺增生的疗效观察及护理体会[J].中国临床新医学,2014,7(7):658-661.
[16]池华茂,彭金娟,杨卉,等.纤维乳管镜在乳腺导管炎性疾病中的应用[J/OL].中华乳腺病杂志(电子版),2013,7(3):14,19.
[17]沈叶,虞贞凤,单远洲,等.纤维乳腺导管镜在乳头溢液疾病诊治中的应用[J].南昌大学学报(医学版),2014,54(2):63-65.
[18]刘明星,吕红发,张金鹏,等.羊乳腺炎乳腺导管及腺泡铸型[J].解剖学报,2017,48(6):721-725.
[19]高海凤,马祥君,汪洁等.乳腺导管探查术治疗乳汁淤积的效果[J/OL].中华乳腺病杂志(电子版),2013,7(3):36-39.
[20]程涓,丁华野,杜玉堂等.肉芽肿性小叶性乳腺炎伴发乳腺导管扩张症的临床病理学观察[J].中华病理学杂志,2013,42(10):665-668.
[21]黄汉源.浆细胞性乳腺炎外科治疗进展:整形外科技术的应用[J/OL].中华乳腺病杂志(电子版),2013,7(3):52-54.