睑板腺功能障碍的病因病机及中医治疗研究进展
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摘要
睑板腺功能障碍是近年来才引起关注的一种常见病,其病因复杂,治疗棘手。中医眼科对该病的认识时间不长,古籍没有直接对应的病名,现代医家一般将其归入"白涩症""睑弦赤烂"等范畴,认为其发病与脾胃相关,或外感风邪、燥邪,或气血不足、运行不畅等。治疗上有从脾胃论治者,亦有从外邪或气血论治者,多结合中医外治方法,取得较好的效果,但多数疗法只能短期改善症状,且缺乏病理学及病原学等验证支持,因而尚需大样本指导下规范的辨证分型及治疗研究。本文对相关内容进行了综述。
Meibomian gland dysfunction is a common, complex and refractory disease which raises concerns in recent years. There is no corresponding name in ancient medical documents, and modern physicians name it as"dry astringent" or "red ulcerated eyelid". It is thought that the pathogenesis is related to spleen and stomach,affected with wind, dryness or deficiency of both qi and blood and its insufficient circulation. Its Chinese medical treatment mainly focuses on spleen and stomach, external pathogen or the qi and blood and often is accompanied with external therapy,which yields favorable effects. However, most therapeutic solutions only have short-term effects without pathological and etiological proofs. Further researches with large sample size and universal syndrome differentiation scheme will be needed to solve this problem. The article summarized the relevant content.
Meibomian gland dysfunction is a common, complex and refractory disease which raises concerns in recent years. There is no corresponding name in ancient medical documents, and modern physicians name it as"dry astringent" or "red ulcerated eyelid". It is thought that the pathogenesis is related to spleen and stomach,affected with wind, dryness or deficiency of both qi and blood and its insufficient circulation. Its Chinese medical treatment mainly focuses on spleen and stomach, external pathogen or the qi and blood and often is accompanied with external therapy,which yields favorable effects. However, most therapeutic solutions only have short-term effects without pathological and etiological proofs. Further researches with large sample size and universal syndrome differentiation scheme will be needed to solve this problem. The article summarized the relevant content.
引文
[1]孙旭光.睑缘炎与睑板腺功能障碍[M].北京:人民卫生出版社,2015:97.
[2]VJ,Stern GA,Hood CI.Histopathology of meibomian gland dysfunction[J].Am J Ophthalmol,1982,94(3):383-387.
[3]段俊国.中西医结合眼科学[M].北京:中国中医药出版社,2010:134
[4]刘莹,颉瑞平.补益肝肾法治疗干眼病30例疗效观察[J].中国中医眼科杂志,2006,16(4):38-39.
[5]夏睦谊.中医药治疗干眼症近况[J].河南中医,2008,28(1):82-84.
[6]佚名.灵枢经[M].王冰,撰注.沈阳:辽宁科学技术出版社,1997:28.
[7]刘泽源,李才锐.睑板腺功能障碍所致干眼的治疗[J].国际眼科杂志,2014,14(2):270-272.
[8]李建良,王蓉,杜红彦,等.中西医结合治疗睑板腺功能障碍性干眼65例观察[J].实用中医药杂志,2016,32(1):35-36.
[9]矫红,武燕,杨亚丽,等.养阴清热·健脾化痰法治疗睑板腺功能障碍及其相关干眼的临床观察[J].现代中医临床,2016,23(1):38-43.
[10]王学珍,贺义恒,余晓,等.睑板腺管疏通术联合中药治疗睑板腺功能障碍(MGD)与干眼症[J].时珍国医国药,2012,23(10):2561-2563.
[11]蒋雪莹,李志鹏,朱宁云.养阴清热法治疗治疗干眼症60例临床研究[J].江苏中医药,2015(47)7:41-42.
[12]周清,任秋锦,岳辉.除湿汤熏蒸治疗睑板腺功能障碍临床观察[J].新中医,2015,47(9):175-176.
[13]黄文刚,朱韶霓,叶雪芳.养血活血法治疗老年性干眼症的效果观察[J].中国社区医师,2015,31(33):83-84.
[14]闵祥玉,杜刚.中青年睑板腺功能障碍所致干眼症的中西医结合疗法分析[J].国际眼科杂志,2016,16(9):1759-1961.
[15]王佳娣,姚靖.中医综合疗法治疗睑板腺功能障碍致蒸发过强型干眼疗效观察[J].中医药学报,2016,44(4):130-132.
[16]魏红领,刘韶瑞,余春红.中老年睑板腺功能障碍所致干眼的综合治疗[J].广东医学,2015,36(8):1278-1280.
[17]徐东,陈国孝,马纲,等.睑板腺功能障碍的中医证候研究[J].浙江中西医结合杂志,2015,25(10):905-907.
[18]黎佳敏,卜文超,林丽,等.睑板腺堵塞性干眼的中医玄府学说探讨[J].云南中医中药杂志,2016,37(11):9-12.
[19]陶荣三.中西医结合治疗睑板腺功能障碍性干眼疗效分析[J].中国现代医生,2016,54(19):83-85.
[20]徐亚玲,刘晖.三仁汤配合睑板腺按摩治疗睑板腺功能异常30例[J].陕西中医,2013,34(6):715-716.
[21]宋艳,赵红.疏肝健脾方离子导入治疗肝郁脾虚型睑板腺导管堵塞型干眼症74例[J].中国中医药现代远程教育,2015,13(10):15-17.
[22]姚靖,王佳娣等,中药清眩润目饮治疗睑板腺功能障碍致蒸发过强型干眼60例的临床观察[J].中医药学报,2014,42(5):51-53.
[23]郭承伟,路斌,吕璐.综合方法治疗睑缘炎相关性干眼症临床观察[J].实用中医药杂志.2011,27(3):178-179.
[24]李能,韦企平.针刺治疗睑板腺功能障碍临床观察[J].上海针灸杂志,2013,32(10):844-845.
[25]李小化.自拟润目汤治疗睑板腺功能障碍性干眼症60例临床观察[J].内蒙古中医药,2015,34(4):23.
[26]冯惠群,海英.田维柱教授应用眼针治疗干眼症经验总结[J].光明中医,2013,28(3):465-467.
[27]李晓华,曹歧新.中药熏洗治疗睑板腺功能障碍的临床观察[J].中国中医药科技,2014,21(1):81-82.
[28]王锋.电脑多功能治疗仪治疗睑板腺功能障碍性干眼症的临床观察[J].社区医学杂志,2012:10(10):38-39.
[29]陈鹏,王志军,宋昱.眼部中药熏蒸睑板按摩治疗睑板腺功能异常的临床观察[J].实用中西医结合临床,2010,10(6):5-6.
[30]姚向超,王延东,黄楚龙.野菊花滴眼液治疗兔蒸发过强型干眼的疗效评价[J].中国药师,2015,18(3):404-406.
[31]郗惠毅.三黄解毒汤外洗治疗睑缘炎[J].中国中医眼科杂志,1995,5(3):183.
[2]VJ,Stern GA,Hood CI.Histopathology of meibomian gland dysfunction[J].Am J Ophthalmol,1982,94(3):383-387.
[3]段俊国.中西医结合眼科学[M].北京:中国中医药出版社,2010:134
[4]刘莹,颉瑞平.补益肝肾法治疗干眼病30例疗效观察[J].中国中医眼科杂志,2006,16(4):38-39.
[5]夏睦谊.中医药治疗干眼症近况[J].河南中医,2008,28(1):82-84.
[6]佚名.灵枢经[M].王冰,撰注.沈阳:辽宁科学技术出版社,1997:28.
[7]刘泽源,李才锐.睑板腺功能障碍所致干眼的治疗[J].国际眼科杂志,2014,14(2):270-272.
[8]李建良,王蓉,杜红彦,等.中西医结合治疗睑板腺功能障碍性干眼65例观察[J].实用中医药杂志,2016,32(1):35-36.
[9]矫红,武燕,杨亚丽,等.养阴清热·健脾化痰法治疗睑板腺功能障碍及其相关干眼的临床观察[J].现代中医临床,2016,23(1):38-43.
[10]王学珍,贺义恒,余晓,等.睑板腺管疏通术联合中药治疗睑板腺功能障碍(MGD)与干眼症[J].时珍国医国药,2012,23(10):2561-2563.
[11]蒋雪莹,李志鹏,朱宁云.养阴清热法治疗治疗干眼症60例临床研究[J].江苏中医药,2015(47)7:41-42.
[12]周清,任秋锦,岳辉.除湿汤熏蒸治疗睑板腺功能障碍临床观察[J].新中医,2015,47(9):175-176.
[13]黄文刚,朱韶霓,叶雪芳.养血活血法治疗老年性干眼症的效果观察[J].中国社区医师,2015,31(33):83-84.
[14]闵祥玉,杜刚.中青年睑板腺功能障碍所致干眼症的中西医结合疗法分析[J].国际眼科杂志,2016,16(9):1759-1961.
[15]王佳娣,姚靖.中医综合疗法治疗睑板腺功能障碍致蒸发过强型干眼疗效观察[J].中医药学报,2016,44(4):130-132.
[16]魏红领,刘韶瑞,余春红.中老年睑板腺功能障碍所致干眼的综合治疗[J].广东医学,2015,36(8):1278-1280.
[17]徐东,陈国孝,马纲,等.睑板腺功能障碍的中医证候研究[J].浙江中西医结合杂志,2015,25(10):905-907.
[18]黎佳敏,卜文超,林丽,等.睑板腺堵塞性干眼的中医玄府学说探讨[J].云南中医中药杂志,2016,37(11):9-12.
[19]陶荣三.中西医结合治疗睑板腺功能障碍性干眼疗效分析[J].中国现代医生,2016,54(19):83-85.
[20]徐亚玲,刘晖.三仁汤配合睑板腺按摩治疗睑板腺功能异常30例[J].陕西中医,2013,34(6):715-716.
[21]宋艳,赵红.疏肝健脾方离子导入治疗肝郁脾虚型睑板腺导管堵塞型干眼症74例[J].中国中医药现代远程教育,2015,13(10):15-17.
[22]姚靖,王佳娣等,中药清眩润目饮治疗睑板腺功能障碍致蒸发过强型干眼60例的临床观察[J].中医药学报,2014,42(5):51-53.
[23]郭承伟,路斌,吕璐.综合方法治疗睑缘炎相关性干眼症临床观察[J].实用中医药杂志.2011,27(3):178-179.
[24]李能,韦企平.针刺治疗睑板腺功能障碍临床观察[J].上海针灸杂志,2013,32(10):844-845.
[25]李小化.自拟润目汤治疗睑板腺功能障碍性干眼症60例临床观察[J].内蒙古中医药,2015,34(4):23.
[26]冯惠群,海英.田维柱教授应用眼针治疗干眼症经验总结[J].光明中医,2013,28(3):465-467.
[27]李晓华,曹歧新.中药熏洗治疗睑板腺功能障碍的临床观察[J].中国中医药科技,2014,21(1):81-82.
[28]王锋.电脑多功能治疗仪治疗睑板腺功能障碍性干眼症的临床观察[J].社区医学杂志,2012:10(10):38-39.
[29]陈鹏,王志军,宋昱.眼部中药熏蒸睑板按摩治疗睑板腺功能异常的临床观察[J].实用中西医结合临床,2010,10(6):5-6.
[30]姚向超,王延东,黄楚龙.野菊花滴眼液治疗兔蒸发过强型干眼的疗效评价[J].中国药师,2015,18(3):404-406.
[31]郗惠毅.三黄解毒汤外洗治疗睑缘炎[J].中国中医眼科杂志,1995,5(3):183.