3种代谢综合征诊断标准在青岛市某院体检人群中的应用分析
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摘要
目的探讨国际糖尿病联盟(IDF)、美国国家胆固醇教育计划成年人治疗方案第三次报告(ATPⅢ)和中华医学会糖尿病学分会(CDS)3种标准在代谢综合征(MS)诊断中的应用。方法选取2016年1-6月在该院体检中心查体的人群共628例为研究对象,统计分析主要查体数据,依据上述3个标准分别进行MS的判断,分析不同性别人群的MS特征。结果研究对象中男278例,女350例;MS的标化患病率分别为44.68%(ATPⅢ标准)、41.55%(IDF标准)和19.20%(CDS标准)。3种标准下男性MS患病率分别为62.71%、59.70%和29.61%;女性患病率分别为29.94%、26.72%和11.54%;ATPⅢ标准和IDF标准诊断符合率为93.95%,IDF和CDS为76.43%,ATPⅢ和CDS为75.00%。ATPⅢ标准和IDF标准下男性血脂紊乱、肥胖/超重、高血压和高血糖检出率分别为82.01%、72.66%、55.40%和19.78%,均高于女性(P<0.05);CDS标准下男性分别为52.88%、51.08%、24.82%和11.78%,均高于女性(P<0.05)。结论 3种标准下,该市查体人群MS的患病率均较高,男性高于女性。血脂紊乱、肥胖/超重和高血压是MS主要异常指标。
Objective To discuss the diagnostic value of International Diabetes Federation(IDF),US National Cholesterol Education Program Adult Treatment Programs Third Report(ATPⅢ)and the Chinese Medical Association Diabetes Society(CDS)in the metabolic syndrome(MS)in the residents who underwent physical examinations.Methods A total of 628 local residents aged 18-88 were included for the study from January to June 2016.The investigation was conducted with questionnaire,health examination and laboratory test.MS was diagnosed according to the three criteria respectively.The rate and constituent ratio served as the main indexes and compared.Features of MS in different genders were also analyzed.Results The standardized incidence rates of MS were 44.68%(ATPⅢ),41.55%(IDF)and 19.20%(CDS)respectively.And the rates of three criteria for male were 62.71%,59.70%and 29.61%,for female were 29.94%,26.72%and 11.54%.The coincidence rates of ATPⅢ and IDF,IDF and CDS,ATPⅢ and CDS diagnostic criteria were 93.95%,76.53%and 75.00%respectively.According to ATPⅢand IDF diagnostic criteria,abnormal rates of male of dyslipidemia,overweight/obesity,hypertension and hyperglycaemia were 82.01%,72.66%,55.40% and19.78%,which were all significantly higher than that of female(P<0.05).Meanwhile,based on CDS diagnostic criteria,the abnormal rates of male were 52.88%,51.08%,24.82%and 11.78%,which were all significantly higher than that of female(P<0.05).Conclusion The MS morbidities of Qingdao residents are high according to three criteria,prevalence rates of male are all higher than that of female.Dyslipidemia,overweight/obesity and hypertension are main abnormal indicators.
Objective To discuss the diagnostic value of International Diabetes Federation(IDF),US National Cholesterol Education Program Adult Treatment Programs Third Report(ATPⅢ)and the Chinese Medical Association Diabetes Society(CDS)in the metabolic syndrome(MS)in the residents who underwent physical examinations.Methods A total of 628 local residents aged 18-88 were included for the study from January to June 2016.The investigation was conducted with questionnaire,health examination and laboratory test.MS was diagnosed according to the three criteria respectively.The rate and constituent ratio served as the main indexes and compared.Features of MS in different genders were also analyzed.Results The standardized incidence rates of MS were 44.68%(ATPⅢ),41.55%(IDF)and 19.20%(CDS)respectively.And the rates of three criteria for male were 62.71%,59.70%and 29.61%,for female were 29.94%,26.72%and 11.54%.The coincidence rates of ATPⅢ and IDF,IDF and CDS,ATPⅢ and CDS diagnostic criteria were 93.95%,76.53%and 75.00%respectively.According to ATPⅢand IDF diagnostic criteria,abnormal rates of male of dyslipidemia,overweight/obesity,hypertension and hyperglycaemia were 82.01%,72.66%,55.40% and19.78%,which were all significantly higher than that of female(P<0.05).Meanwhile,based on CDS diagnostic criteria,the abnormal rates of male were 52.88%,51.08%,24.82%and 11.78%,which were all significantly higher than that of female(P<0.05).Conclusion The MS morbidities of Qingdao residents are high according to three criteria,prevalence rates of male are all higher than that of female.Dyslipidemia,overweight/obesity and hypertension are main abnormal indicators.
引文
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[12]邵永强,樊丽辉,李江峰,等.温州市居民代谢综合征患病率及影响因素调查[J].中国慢性病预防与控制,2016,24(6):419-422.
[13]FEI S,BIN G,LI W,et al.Agreement Between the JCD-CG,Revised NCEP-ATPⅢ,and IDF Definitions of Metabolic Syndrome in a Northwestern Chinese Population[J].Diabetes Ther,2018,9(4):1457-1468.
[14]姚崇华,胡以松,翟凤英,等.我国2002年代谢综合征的流行情况[J].中国糖尿病杂志,2007,15(6):332-335.
[15]曹乾斌,孙健平,张东峰,等.2009-2010年青岛市中老年人代谢综合征患病情况及其影响因素分析[J].预防医学论坛,2013,19(1):9-11.
[16]ATHYROS V G,GANOTAKIS E S,ELISAEM S,et al.Prevalence of vascular disease in metabolic syndrome using three proposed definitions[J].Int J Cardiol,2007,117(2):204-210.
[2]CAMERON A J,ZIMMET P Z,SHAW J E,et al.The metabolic syndrome:in need of a global mission statement[J].Diabet Med,2009,26(3):306-309.
[3]FORD E S,LI C,ZHAO G X.Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the US[J].J Diabetes,2010,2(3):180-193.
[4]LI R,LI W,LUN Z,et al.Prevalence of metabolic syndrome in Mainland China:a meta-analysis of published studies[J].BMC Public Health,2016,16:296.
[5]HUI Z,HUI L,LIU W,et al.Prevalence of metabolic syndrome among adults with liver function injury in rural area of Southwest China:a cross-sectional study[J].Sci Rep,2017,7(1):5518.
[6]ALBERLI K G,ZIMMET P,SHAW J,et al.The metabolic syndrome-a new worldwide definition[J].Lancet,2005,366(9491):1059-1062.
[7]GRUNDY S M,CLEEMAN J I,RIFKIND B M,et al.Cholesterol lowering in the elderly population.Coordinating Committee of the National Cholesterol Education Program[J].Arch Intern Med,1999,159(15):1670-1678.
[8]中华医学会糖尿病学分会代谢综合征研究协作组.中华医学会糖尿病学分会关于代谢综合征的建议[J].中华糖尿病杂志,2004,12(3):156-161.
[9]CAMERON A J,SHAW J E,ZIMMET P Z.The metabolic syndrome:prevalence in worldwide populations[J].Endocrinol Metab Clin North Am,2004,33(2):351-375.
[10]王睿,彭年春,时立新,等.四种代谢综合征诊断标准在贵阳市成人流行病学调查中的应用比较[J].中国糖尿病杂志,2014,6(8):606-610.
[11]刘庆敏,马先富,任艳军,等.三种代谢综合征诊断标准在杭州市企业职工人群中的应用比较[J].中国预防医学杂志,2015,16(11):865-870.
[12]邵永强,樊丽辉,李江峰,等.温州市居民代谢综合征患病率及影响因素调查[J].中国慢性病预防与控制,2016,24(6):419-422.
[13]FEI S,BIN G,LI W,et al.Agreement Between the JCD-CG,Revised NCEP-ATPⅢ,and IDF Definitions of Metabolic Syndrome in a Northwestern Chinese Population[J].Diabetes Ther,2018,9(4):1457-1468.
[14]姚崇华,胡以松,翟凤英,等.我国2002年代谢综合征的流行情况[J].中国糖尿病杂志,2007,15(6):332-335.
[15]曹乾斌,孙健平,张东峰,等.2009-2010年青岛市中老年人代谢综合征患病情况及其影响因素分析[J].预防医学论坛,2013,19(1):9-11.
[16]ATHYROS V G,GANOTAKIS E S,ELISAEM S,et al.Prevalence of vascular disease in metabolic syndrome using three proposed definitions[J].Int J Cardiol,2007,117(2):204-210.