河北省廊坊市2009-2016年甲型H1N1流感流行特征研究
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摘要
目的分析廊坊市2009-2016年间本地甲型H1N1流感疫情的流行病学特征,研判其在廊坊市的流行规律,提出相应防控策略。方法采集临床诊断病例3 d以内的咽拭子标本,采用实时荧光定量多聚核苷酸链式反应,检测甲型H1N1流感病毒核酸。对廊坊市2009-2016年8年的甲型H1N1流感病例资料及检测结果进行流行病学描述性分析。结果 2009-2016年廊坊市流感实验室共检测并报告365例甲型H1N1流感病例,其中学生188例(占51. 51%),发病年龄以0～20岁为主(246例,占67. 40%)。全市共10起甲型H1N1流感聚集性疫情,11月最多。结论学校是甲型H1N1流感疫情多发场所,应坚持"四早"原则。社会各界要加强宣传,督促学校落实防控措施,建议尽早接种疫苗,积极落实学校传染病防控措施。
Objective To analyze the epidemiological characteristics of local influenza A H1N1 epidemic in Langfang City from2009 to 2016, to study the epidemic rules in Langfang City and put forward corresponding prevention and control strategies. Methods Throat swab specimens within three days of clinical diagnosis were collected and real-time fluorescence quantitative polynucleotide chain reaction was used to detect influenza A( H1N1) virus nucleic acid. Epidemiological descriptive analysis was carried out on influenza A H1N1 case data and test results in Langfang City from 2009 to 2016. Results A total of 365 cases of influenza A H1N1 influenza were detected and reported in the 2009-2016 Langfang City Influenza Laboratory,including 188students( 51. 51%). The age of onset was 0 to 20 years old( 246 cases,accounting for 67. 40%). A total of 10 H1N1 flu epidemics occurred in the city,mostly in November. Conclusion School is a place where there are a number of H1N1 flu epidemics,and should adhere to the "four early" principle. All sectors of the society should step up publicity and supervise schools to implement prevention and control measures. It is recommended that vaccination should be given as soon as possible and prevention and control measures for infectious diseases in schools should be actively implemented.
Objective To analyze the epidemiological characteristics of local influenza A H1N1 epidemic in Langfang City from2009 to 2016, to study the epidemic rules in Langfang City and put forward corresponding prevention and control strategies. Methods Throat swab specimens within three days of clinical diagnosis were collected and real-time fluorescence quantitative polynucleotide chain reaction was used to detect influenza A( H1N1) virus nucleic acid. Epidemiological descriptive analysis was carried out on influenza A H1N1 case data and test results in Langfang City from 2009 to 2016. Results A total of 365 cases of influenza A H1N1 influenza were detected and reported in the 2009-2016 Langfang City Influenza Laboratory,including 188students( 51. 51%). The age of onset was 0 to 20 years old( 246 cases,accounting for 67. 40%). A total of 10 H1N1 flu epidemics occurred in the city,mostly in November. Conclusion School is a place where there are a number of H1N1 flu epidemics,and should adhere to the "four early" principle. All sectors of the society should step up publicity and supervise schools to implement prevention and control measures. It is recommended that vaccination should be given as soon as possible and prevention and control measures for infectious diseases in schools should be actively implemented.
引文
[1]卫生部.流行性感冒诊疗方案(2018年版)[Z]. 2018-01-24.
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[8]蔡翁义,蔡颖,魏锐,等.几种甲型H1N1流感病毒SYBR GreenⅠ荧光RT-PCR检测方法的验证[J].口岸卫生控制,2013,18(6):28-33.
[9]曾光,张丽杰.中国如何更好地应对甲型H1N1流感大流行[J].中华流行病学杂志,2009,30(7):653-655.
[10]李燕婷,陈健,孔利群,等.上海市1999-2003年流行性感冒流行特征分析[J].中国公共卫生,2005,21(1):127-128.
[11]方林,欧剑鸣,蔡少健,等. 2009-09/10福建省学校聚集性甲型H1N1流感疫情分析[J].预防医学情报杂志,2009,25(12):1010-1012.
[12]郭醉元,李东力.甲型H1N1流感的流行病学与预防控制[J].沈阳部队医药,2010,23(1):62-63.
[13]段玮,杨鹏,田丽丽,等. 2009年北京市学生甲型H1N1流感流行特征[J].首都公共卫生,2010,4(3):99-102.
[14]韦懿芸,郭菁,华伟玉,等.北京市某中学聚集性甲型H1N1流感暴发疫情调查[J].中国学校卫生,2011,32(7):809-811.
[15]曾昭长,邱丽,曾祥洁,等.海南省甲型H1N1流感血清流行病学调查[J].中国公共卫生,2011,27(8):1054-1056.
[2]中国疾病预防控制中心.甲型H1NI流感流行病学调查和暴发疫情处置技术指南(2009版)[Z]. 2009-05-26.
[3]庞星火,杨鹏,李爽,等.北京市2009年甲型H1N1流感患者密切接触者的流行病学特点[J].中华结核和呼吸杂志,2011,34(5):348-352.
[4]涂文校,陈园生,卢亮平,等. 2009年甲型H1N1流感主要流行病学特征[J].疾病监测,2009,24(12):906-909.
[5]蔡润. 2009年北京市海淀区聚集性甲型H1N1流感疫情状况[J].首都公共卫生,2011,5(1):6-8.
[6]周苏建.一起甲型H1N1流感暴发疫情的调查报告[J].江苏预防医学,2010,21(3):26-27.
[7]王善雨,高春玉,姚新华,等.甲型H1N1流感的流行病学特征及预防控制[J].中国当代医药,2009,16(15):37-39.
[8]蔡翁义,蔡颖,魏锐,等.几种甲型H1N1流感病毒SYBR GreenⅠ荧光RT-PCR检测方法的验证[J].口岸卫生控制,2013,18(6):28-33.
[9]曾光,张丽杰.中国如何更好地应对甲型H1N1流感大流行[J].中华流行病学杂志,2009,30(7):653-655.
[10]李燕婷,陈健,孔利群,等.上海市1999-2003年流行性感冒流行特征分析[J].中国公共卫生,2005,21(1):127-128.
[11]方林,欧剑鸣,蔡少健,等. 2009-09/10福建省学校聚集性甲型H1N1流感疫情分析[J].预防医学情报杂志,2009,25(12):1010-1012.
[12]郭醉元,李东力.甲型H1N1流感的流行病学与预防控制[J].沈阳部队医药,2010,23(1):62-63.
[13]段玮,杨鹏,田丽丽,等. 2009年北京市学生甲型H1N1流感流行特征[J].首都公共卫生,2010,4(3):99-102.
[14]韦懿芸,郭菁,华伟玉,等.北京市某中学聚集性甲型H1N1流感暴发疫情调查[J].中国学校卫生,2011,32(7):809-811.
[15]曾昭长,邱丽,曾祥洁,等.海南省甲型H1N1流感血清流行病学调查[J].中国公共卫生,2011,27(8):1054-1056.