低频重复经颅磁刺激治疗精神分裂症幻听的效果
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摘要
目的探讨低频重复经颅磁刺激治疗精神分裂症幻听的效果。方法将120例精神分裂症幻听患者随机分成对照组(n=65,假刺激治疗)和观察组(n=55,低频重复经颅磁刺激治疗),对比2组患者PANSS量表中各因子评分和不良反应发生情况。结果观察组患者治疗2周末、4周末以及6周末的阳性症状、一般精神病理、幻听评分以及麻木感发生概率(3.34%)、头痛发生概率(5.45%)均低于对照组(P<0.05),阴性症状治疗前后未发生明显变化(P>0.05)。结论低频重复经颅磁刺激治疗精神分裂症幻听安全有效。
Objective To investigate the effect of low frequency repetitive transcranial magnetic stimulation in the treatment of auditory hallucination of schizophrenia.Methods A lot of 120 patients with auditory hallucination of schizophrenia were randomly divided into a control group(n=65, sham treatment) and an observation group(n=55, low frequency repetitive transcranial magnetic stimulation), and each factor score of PANSS scale and adverse reactions were compared between two groups.Results Two weeks, four weeks, and six weeks after the treatment, the positive symptoms, general psychopathology, auditory hallucination score, numbness probability(3.34%), and headache occurrence probability(5.45%) in the observation group were lower than those in the control group(P < 0.05), but the negative symptoms did not change significantly before and after the treatment(P > 0.05). Conclusion Low frequency repetitive transcranial magnetic stimulation is safe and effective in the treatment of auditory hallucination of schizophrenia.
Objective To investigate the effect of low frequency repetitive transcranial magnetic stimulation in the treatment of auditory hallucination of schizophrenia.Methods A lot of 120 patients with auditory hallucination of schizophrenia were randomly divided into a control group(n=65, sham treatment) and an observation group(n=55, low frequency repetitive transcranial magnetic stimulation), and each factor score of PANSS scale and adverse reactions were compared between two groups.Results Two weeks, four weeks, and six weeks after the treatment, the positive symptoms, general psychopathology, auditory hallucination score, numbness probability(3.34%), and headache occurrence probability(5.45%) in the observation group were lower than those in the control group(P < 0.05), but the negative symptoms did not change significantly before and after the treatment(P > 0.05). Conclusion Low frequency repetitive transcranial magnetic stimulation is safe and effective in the treatment of auditory hallucination of schizophrenia.
引文
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[8]徐丽莹.常规联合低频重复经颅磁刺激治疗精神分裂症顽固性幻听疗效观察[J].人民军医,2015,58(11):1332-1333.
[9]张翠红,张岿,张洁,等.低频重复经颅磁刺激对精神分裂症顽固性幻听的随机双盲对照研究[J].中国民康医学,2014,26(16):20-21.
[10]王芳,傅岳文,张芳.低频重复经颅磁刺激治疗精神分裂症患者顽固性幻听的疗效观察[J].临床医药文献杂志(电子版),2016,3(43):8526-8527.
[2]任季冬,阮洪梅,胡宇,低频重复经颅磁刺激治疗精神分裂症难治性幻听的临床研究[J].临床医学研究与实践,2016,1(1):54-54.
[3]张少霞,李一凡.抗精神病药物联合低频重复经颅磁刺激治疗对精神分裂症顽固性幻听的临床对照研究[J].中外医疗,2016,35(30):4-6.
[4]廖更生.低频重复经颅磁刺激治疗精神分裂症顽固性幻听对照研究[J].临床心身疾病杂志,2016,22(5):32-34.
[5]马世发.老年精神分裂症顽固性幻听采用低频重复经颅磁刺激治疗的效果观察[J].世界最新医学信息文摘(电子版),2014,14(29):140-140.
[6]陈筱章,彭玉琴,邓凡.精神分裂症顽固性幻听实施双背侧前额叶低频重复经颅磁刺激治疗的效果研究[J].中国医学创新,2014,11(7):71-73.
[7]彭光海,周振和,袁国桢.低频重复经颅磁刺激治疗精神分裂症幻听症状疗效的Meta分析[J].中国健康心理学杂志,2014,22(9):1281-1285.
[8]徐丽莹.常规联合低频重复经颅磁刺激治疗精神分裂症顽固性幻听疗效观察[J].人民军医,2015,58(11):1332-1333.
[9]张翠红,张岿,张洁,等.低频重复经颅磁刺激对精神分裂症顽固性幻听的随机双盲对照研究[J].中国民康医学,2014,26(16):20-21.
[10]王芳,傅岳文,张芳.低频重复经颅磁刺激治疗精神分裂症患者顽固性幻听的疗效观察[J].临床医药文献杂志(电子版),2016,3(43):8526-8527.