胸腔镜下肺癌根治术对早期NSCLC患者近远期预后的影响

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英文篇名：Effect of thoracoscopic radical resection on the prognosis of patients with early stage NSCLC 作者：刘向前 英文作者：Liu Xiangqian;The First Affiliated Hospital of Nanyang Medical College; 关键词：早期非小细胞肺癌 ; 胸腔镜 ; 肺癌根治术 ; 近远期预后 英文关键词：Early NSCLC;;Thoracoscopic surgery;;Radical resection;;Near and long-term prognosis 中文刊名：HZYZ 英文刊名：Journal of Heze Medical College 机构：南阳医学高等专科学校第一附属医院; 出版日期：2019-03-15 出版单位：菏泽医学专科学校学报 年：2019 期：v.31;No.117 语种：中文; 页：HZYZ201901004 页数：4 CN：01 ISSN：37-1289/R 分类号：17-19+48

摘要

目的探讨胸腔镜下肺癌根治术对早期非小细胞肺癌(NSCLC)患者近远期预后的影响。方法选择早期NSCLC患者80例,按照手术方式分为观察组和对照组。观察组42例采用胸腔镜下肺癌根治术,对照组38例行采用传统开胸切除术治疗,对比两组治疗后手术指标、不良反应发生率以及无瘤生存率和总生存率。结果观察组患者术中出血量、术后引流量少于对照组,术后疼痛程度低于对照组,住院时间短于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率低于对照组不良反应发生率,差异有统计学意义(P<0.05);观察组1、3、5年无瘤生存率高于对照组,差异有统计学意义(P<0.05);两组患者总生存率比较,差异无统计学意义(P>0.05)。结论早期NSCLC采用胸腔镜下肺癌根治术治疗可明显降低术中出血量、术后引流量、术后疼痛程度、住院时间及不良反应发生率,其中位无瘤生存率较高。
        Objective To explore the effect of thoracoscopic radical resection on the prognosis of patients with early stage non-small cell lung cancer(NSCLC). Methods Eighty patients with early stage NSCLC were enrolled and divided into the observation group(42 cases) and the control group(38 cases) according to the operation method. The observation group used thoracoscopic radical resection and the control group used traditional thoracotomy. The surgical index, adverse reaction rate, tumor-free survival rate and overall survival rate were compared between the two groups after treatment. Results The amount of intraoperative blood loss and postoperative drainage volume were lower than those in the control group. The postoperative pain was less than that in the control group. The hospital stay was shorter than that in the control group. The difference was statistically significant(P<0.05). The incidence of adverse reactions in the observation group was 7.14%, which was lower than that in the control group(26.32%). The difference was statistically significant(P<0.05). The tumor-free survival rate of the observation group was higher than that of the control group(P<0.05). The difference was statistically significant(P<0.05). The overall survival rate of the two groups were compared with P>0.05. Conclusion Thoracoscopic radical resection can significantly reduce the amount of intraoperative blood loss, postoperative drainage volume, postoperative pain, hospitalization time, adverse reaction rate and rose the overall survival rate in the treatment of early stage NSCLC.

引文

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