礞石滚痰汤加减治疗痰热内扰型不寐30例
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摘要
目的:观察礞石滚痰汤治疗痰热内扰型不寐的临床疗效。方法:将60例患者随机分为观察组和对照组,每组30例。观察组予以礞石滚痰汤加减治疗,1剂/d,2次/d。对照组予以阿普唑仑。0.4 mg,口服,1次/d。2组均连续治疗4周,比较2组给药前后匹兹堡睡眠质量指数(PSQI)、体质评分和临床疗效。结果:总有效率观察组为86.67%,对照组为60.00%,2组比较差异有统计学意义(P<0.05)。PSQI评分及体质评分治疗前后2组组内比较,差异有统计学意义(P<0.05);治疗后组间比较差异也有统计学意义(P<0.05)。结论:礞石滚痰汤治疗痰热型不寐,可明显改善患者睡眠质量。
Objective: To observe clinical effects of MengShi GunTan Tang in treating insomnia of phlegmheat internal disturbance pattern. Methods: Sixty patients were assigned to two groups, 30 cases each group, the observation group took modified MengShi GunTan Tang, one dose each day, twice each day. and the control group alprazolam 0.4 mg, oral administration once each day. Both groups were treated for four weeks consecutively, to compare clinical effects, constitutional scores and PSQI before and after medicating in both groups. Results: Total effective rate of the observation group was 86.67%, higher than 60.00% of the control group, and the difference showed statistical meaning(P<0.05). The difference had statistical meaning in the comparisons of PSQI scores and constitutional scores within two groups before and after treating(P <0.05); the difference presented statistical meaning in the comparisons between both groups after treating(P <0.05). Conclusion: MengShi GunTan Tang is effec tive in treating insomnia of phlegm-heat internal disturbance pattern, and it could obvionsly improve sleep quality.
Objective: To observe clinical effects of MengShi GunTan Tang in treating insomnia of phlegmheat internal disturbance pattern. Methods: Sixty patients were assigned to two groups, 30 cases each group, the observation group took modified MengShi GunTan Tang, one dose each day, twice each day. and the control group alprazolam 0.4 mg, oral administration once each day. Both groups were treated for four weeks consecutively, to compare clinical effects, constitutional scores and PSQI before and after medicating in both groups. Results: Total effective rate of the observation group was 86.67%, higher than 60.00% of the control group, and the difference showed statistical meaning(P<0.05). The difference had statistical meaning in the comparisons of PSQI scores and constitutional scores within two groups before and after treating(P <0.05); the difference presented statistical meaning in the comparisons between both groups after treating(P <0.05). Conclusion: MengShi GunTan Tang is effec tive in treating insomnia of phlegm-heat internal disturbance pattern, and it could obvionsly improve sleep quality.
引文
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[2]国家中医药管理局.中医病证诊断疗效标准[M].北京:中国医药科技出版社,2012:32.
[3]刘贤臣,唐茂芹,胡蕾,等.匹兹堡睡眠质量指数的信度和效度研究[J].中华精神科杂志,1996,29(2):103-107.
[4]中华中医药学会.中医体质分类与判定[M].北京:中华中医药出版社,2009:3.
[5]佘姝娅,杨茂农,陈霞,等.失眠体质类型与经络检测仪辅助诊断的相关性研究[J].西部中医药,2017,30(10):122-124.
[6]彭晓明,丁晓华.围绝经期失眠症的治疗新进展[J].西部中医药,2018,31(2):141-145.
[7]张耕源,张建春,谢娜,等.舒肝解郁胶囊对围绝经期失眠妇女血清FSH、IL-1β及5-HT的影响[J].西部中医药,2018,31(4):5-9.