乙型病毒性肝炎相关晚期肝病的抗病毒治疗效果观察
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摘要
目的分析抗病毒疗法治疗乙型病毒性肝炎相关晚期肝病的临床效果。方法选取我院2016年1月～9月收治的乙型病毒性肝炎相关晚期肝病患者80例为研究对象,随机分为对照组和观察组,各40例。对照组患者行常规治疗,观察组患者行抗病毒治疗,比较两组治疗效果。结果原发性肝癌患者中,对照组治疗有效率为60.00%,观察组治疗有效率为88.89%;肝硬化患者中,对照组治疗有效率为64.29%,观察组治疗有效率为92.31%;重型肝炎患者中,对照组治疗有效率为68.75%,观察组治疗有效率为94.44%,组间数据比较,差异均有统计学意义(P<0.05)。结论针对乙型病毒性肝炎相关晚期肝病患者进行治疗时,采用抗病毒治疗疗法可以达到理想的治疗效果,有利于患者康复。
Objective To analyze the clinical effect of antiviral therapy in the treatment of advanced liver disease associated with hepatitis B virus.Methods 80 patients with advanced hepatitis B associated with hepatitis B admitted to our hospital from January to September 2016 were enrolled in the study. They were randomly divided into control group and observation group, 40 cases each. Patients in the control group underwent routine treatment, and patients in the observation group underwent antiviral therapy, and the effects of the two groups were compared. Results In the patients with primary liver cancer, the effective rate of the control group was 60.00%, and the effective rate of the observation group was 88.89%. Among the patients with liver cirrhosis, the effective rate of the control group was 64.29%, and the effective rate of the observation group was 92.31%. Among the patients with hepatitis, the effective rate of the control group was 68.75%, and the effective rate of the observation group was 94.44%,the difference between the groups was statistically significant(P<0.05). Conclusion When treating patients with hepatitis B-related advanced liver disease, antiviral therapy can achieve the desired therapeutic effect and is beneficial to the rehabilitation of patients.
Objective To analyze the clinical effect of antiviral therapy in the treatment of advanced liver disease associated with hepatitis B virus.Methods 80 patients with advanced hepatitis B associated with hepatitis B admitted to our hospital from January to September 2016 were enrolled in the study. They were randomly divided into control group and observation group, 40 cases each. Patients in the control group underwent routine treatment, and patients in the observation group underwent antiviral therapy, and the effects of the two groups were compared. Results In the patients with primary liver cancer, the effective rate of the control group was 60.00%, and the effective rate of the observation group was 88.89%. Among the patients with liver cirrhosis, the effective rate of the control group was 64.29%, and the effective rate of the observation group was 92.31%. Among the patients with hepatitis, the effective rate of the control group was 68.75%, and the effective rate of the observation group was 94.44%,the difference between the groups was statistically significant(P<0.05). Conclusion When treating patients with hepatitis B-related advanced liver disease, antiviral therapy can achieve the desired therapeutic effect and is beneficial to the rehabilitation of patients.
引文
[1]李开林.抗病毒治疗对乙肝相关晚期肝病患者疗效的观察[J].医药前沿,2016,6(26):127-128.
[2]郑建铭,黄翀,鱼康康,等.慢性乙型病毒性肝炎慢加急性肝衰竭患者拉米夫定与恩替卡韦抗病毒治疗的短期病死率比较[J].中国感染与化疗杂志,2018,18(2):132-136.
[3]蒋珊珊.乙肝相关性慢性肝病患者肠道菌群的比较及核苷类抗病毒药物对其的影响[D].广西医科大学,2016.
[4]金彩婷,郭利伟,梁伟峰等.慢性乙型病毒性肝炎肝纤维化无创性血清诊断指标研究进展[J].中华实验和临床感染病杂志(电子版),2018,12(1):11-14.
[5]陈词.丁岗强:乙肝患者抗病毒治疗停药问题[J].肝博士,2017(5):14-15.
[6]张菁,崔剑巍,成伟忠,等.基于"伏邪"说的肝复安治疗慢性乙型病毒性肝炎患者铁代谢异常临床观察[J].上海中医药杂志,2016(8):38-42.
[7]潘佳,江南.慢性乙型病毒性肝炎抗病毒治疗及疗效预测因素的研究进展[J].实用医院临床杂志,2016,13(2):147-151.
[8]刘粟,张锐,邱勇,等.慢性乙型病毒性肝炎患者抗病毒治疗依从性及影响因素的分析[J].湖北民族学院学报(医学版),2017,34(1):44-46.
[2]郑建铭,黄翀,鱼康康,等.慢性乙型病毒性肝炎慢加急性肝衰竭患者拉米夫定与恩替卡韦抗病毒治疗的短期病死率比较[J].中国感染与化疗杂志,2018,18(2):132-136.
[3]蒋珊珊.乙肝相关性慢性肝病患者肠道菌群的比较及核苷类抗病毒药物对其的影响[D].广西医科大学,2016.
[4]金彩婷,郭利伟,梁伟峰等.慢性乙型病毒性肝炎肝纤维化无创性血清诊断指标研究进展[J].中华实验和临床感染病杂志(电子版),2018,12(1):11-14.
[5]陈词.丁岗强:乙肝患者抗病毒治疗停药问题[J].肝博士,2017(5):14-15.
[6]张菁,崔剑巍,成伟忠,等.基于"伏邪"说的肝复安治疗慢性乙型病毒性肝炎患者铁代谢异常临床观察[J].上海中医药杂志,2016(8):38-42.
[7]潘佳,江南.慢性乙型病毒性肝炎抗病毒治疗及疗效预测因素的研究进展[J].实用医院临床杂志,2016,13(2):147-151.
[8]刘粟,张锐,邱勇,等.慢性乙型病毒性肝炎患者抗病毒治疗依从性及影响因素的分析[J].湖北民族学院学报(医学版),2017,34(1):44-46.