肌力、脂肪含量与绝经后骨质疏松症患者骨密度T值的相关性分析
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摘要
目的探讨肌力、脂肪含量与绝经后骨质疏松症患者骨密度T值的相关性,为临床防治绝经后骨质疏松症提供依据。方法选择2015年6月-2017年6月江苏省中医院骨伤科收治的骨质疏松症患者84例设为观察组,根据骨密度T值测定结果分为骨量减少组32例、骨质疏松组41例及严重骨质疏松组11例;另选择同期入院健康体检者40例设为对照组。采用Inbody720型电子背力计分别测定各组腰背部伸肌力(取平均值),利用美国Hologic公司生产的全身型双能X线骨密度仪测定各组全身脂肪及腰椎L1～4骨密度值,采用SPSS Pearson相关性分析软件对肌力、脂肪含量对绝经后骨质疏松症患者骨密度T值的相关性进行分析。结果观察组绝经后骨质疏松症患者肌力、骨密度水平低于对照组,腹部脂肪含量高于对照组,差异均有统计学意义(P<0. 05)。骨量减少组肌力、骨密度水平高于骨质疏松组和严重骨质疏松组,脂肪含量低于骨质疏松组和严重骨质疏松组,差异均有统计学意义(P<0. 05);骨质疏松组肌力、骨密度水平高于严重骨质疏松组,脂肪含量低于严重骨质疏松组,差异均有统计学意义(P<0. 05)。绝经后骨质疏松症骨密度水平与肌力呈正相关性(P<0. 05),与脂肪含量呈负相关性(P<0. 05)。结论绝经后骨质疏松症患者肌力、脂肪含量较少,并且与骨密度之间存在紧密的联系。
Objective To explore the correlation between muscle strength,fat content and bone mineral density( BMD) T value in patients with postmenopausal osteoporosis, provide a basis for clinical prevention and treatment of postmenopausal osteoporosis.Methods From June 2015 to June 2017,84 patients with postmenopausal osteoporosis treated in Department of Orthopedics,Jiangsu Provincial Hospital of Traditional Chinese Medicine were selected as observation group,according to the results of BMD T value,the patients were divided into osteopenia group( 32 patients),osteoporosis group( 41 patients),and severe osteoporosis group( 11 patients). Forty women receiving healthy physical examination in the hospital during the same period were selected as control group. Inbody720 electronic dynamometer was used to detect back body extensor strength. Whole-body dual-energy X-ray bone density meter was used to detect body fat and lumbar vertebrae L1-4 BMD. Pearson correlation analysis software was used to analyze the correlation between muscle strength,fat content and BMD T value in patients with postmenopausal osteoporosis. Results Muscle strength and BMD in observation group were statistically significantly lower than those in control group,while abdominal fat content in observation group was statistically significantly higher than that in control group( P<0. 05). Muscle strength and BMD in osteopenia group were statistically significantly higher than those in osteoporosis group and severe osteoporosis group,while abdominal fat content in osteopenia group was statistically significantly lower than those in osteoporosis group and severe osteoporosis group( P<0. 05). Muscle strength and BMD in osteoporosis group were statistically significantly higher than those in severe osteoporosis group,while abdominal fat content in osteoporosis group was statistically significantly lower than that in severe osteoporosis group( P<0. 05). BMD was positively correlated with muscle strength in patients with postmenopausal osteoporosis( P<0. 05),BMD was negatively correlated with fat content( P<0. 05). Conclusion Muscle strength and abdominal fat content in patients with postmenopausal osteoporosis are low,which are closely correlated with BMD.
Objective To explore the correlation between muscle strength,fat content and bone mineral density( BMD) T value in patients with postmenopausal osteoporosis, provide a basis for clinical prevention and treatment of postmenopausal osteoporosis.Methods From June 2015 to June 2017,84 patients with postmenopausal osteoporosis treated in Department of Orthopedics,Jiangsu Provincial Hospital of Traditional Chinese Medicine were selected as observation group,according to the results of BMD T value,the patients were divided into osteopenia group( 32 patients),osteoporosis group( 41 patients),and severe osteoporosis group( 11 patients). Forty women receiving healthy physical examination in the hospital during the same period were selected as control group. Inbody720 electronic dynamometer was used to detect back body extensor strength. Whole-body dual-energy X-ray bone density meter was used to detect body fat and lumbar vertebrae L1-4 BMD. Pearson correlation analysis software was used to analyze the correlation between muscle strength,fat content and BMD T value in patients with postmenopausal osteoporosis. Results Muscle strength and BMD in observation group were statistically significantly lower than those in control group,while abdominal fat content in observation group was statistically significantly higher than that in control group( P<0. 05). Muscle strength and BMD in osteopenia group were statistically significantly higher than those in osteoporosis group and severe osteoporosis group,while abdominal fat content in osteopenia group was statistically significantly lower than those in osteoporosis group and severe osteoporosis group( P<0. 05). Muscle strength and BMD in osteoporosis group were statistically significantly higher than those in severe osteoporosis group,while abdominal fat content in osteoporosis group was statistically significantly lower than that in severe osteoporosis group( P<0. 05). BMD was positively correlated with muscle strength in patients with postmenopausal osteoporosis( P<0. 05),BMD was negatively correlated with fat content( P<0. 05). Conclusion Muscle strength and abdominal fat content in patients with postmenopausal osteoporosis are low,which are closely correlated with BMD.
引文
[1]卞庆来,邹小娟,戴红,等.绝经后骨质疏松症患者舌象瘀斑指数与骨密度T值及骨痛VAS评分相关性探讨[J].中国骨质疏松杂志,2016,22(3):326-329.
[2] Hadji P,Papaioannou N,Gielen E,et al. Persistence,adherence,and medication-taking behavior in women with postmenopausal osteoporosis receiving denosumab in routine practice in Germany,Austria,Greece,and Belgium:12-month results from a European non-interventional study[J]. Osteoporosis Int, 2015, 26(10):2479-2489.
[3]蒋雪生,李建有,周国顺,等.绝经后骨质疏松症发生骨折的影响因素Logistic回归分析[J].中华实验外科杂志,2016,33(9):2233-2236.
[4]姚喆,王啸,李光飞,等.铁蓄积与绝经后髋部骨质疏松性骨折的相关性分析[J].中华创伤杂志,2016,32(6):510-515.
[5]李炎,周璇,玉洪荣,等.仫佬族绝经前与绝经后女性体成分和骨密度的相关性研究[J].中国骨质疏松杂志,2017,23(5):657-661.
[6]郁新迪,张育,李国青,等.风湿活动度预测绝经后女性类风湿关节炎患者骨密度的研究[J].中国骨质疏松杂志,2016,22(5):556-559.
[7] Leder BZ,Tsai JN,Uihlein AV,et al. Denosumab and teriparatide transitions in postmenopausal osteoporosis(the DATA-Switch study):extension of a randomised controlled trial[J]. Lancet,2015,386(9999):1147.
[8]张海林,孙惠清,倪卓民,等.绝经后妇女膝关节骨性关节炎和骨质疏松症发生率关系[J].中国骨质疏松杂志,2016,22(4):463-465.
[9]米思奇.老年女性下肢关节等速肌力与骨密度的相关性研究[J].中国骨质疏松杂志,2016,22(7):815-817.
[10]卢涛,宋清华.太极拳、步行及舞蹈锻炼对老年女性下肢肌力、骨密度及平衡能力的影响[J].中华物理医学与康复杂志,2015,37(2):124-127.
[11]潘凌,方圆,陈琳,等.简易机体功能评估和计时起走测试评估老年人肌肉功能和肌力及肌量的价值研究[J].中国全科医学,2017,20(2):150-153.
[12]郭宏焘.户外负重有氧运动结合局部肌力训练在老年骨质疏松预防中的效果研究[J].中国骨质疏松杂志,2015,21(8):941-944.
[13] Liu X D,Cai F,Liu L,et al. MicroRNA-210 is involved in the regulation of postmenopausal osteoporosis through promotion of VEGF expression and osteoblast differentiation[J]. Biol Chem,2015,396(4):339-347.
[14]程力,常九州,周卫东.绝经后2型糖尿病患者骨硬化蛋白、PINP、CTX与骨密度相关性研究[J].中国骨质疏松杂志,2017,23(7):874-878.
[15]马俊义,施振宇,史晓林.穴位贴敷疗法对绝经后骨质疏松患者血清OPG、RANKL和髋部骨密度的影响[J].中国骨质疏松杂志,2017,23(7):921-925.
[2] Hadji P,Papaioannou N,Gielen E,et al. Persistence,adherence,and medication-taking behavior in women with postmenopausal osteoporosis receiving denosumab in routine practice in Germany,Austria,Greece,and Belgium:12-month results from a European non-interventional study[J]. Osteoporosis Int, 2015, 26(10):2479-2489.
[3]蒋雪生,李建有,周国顺,等.绝经后骨质疏松症发生骨折的影响因素Logistic回归分析[J].中华实验外科杂志,2016,33(9):2233-2236.
[4]姚喆,王啸,李光飞,等.铁蓄积与绝经后髋部骨质疏松性骨折的相关性分析[J].中华创伤杂志,2016,32(6):510-515.
[5]李炎,周璇,玉洪荣,等.仫佬族绝经前与绝经后女性体成分和骨密度的相关性研究[J].中国骨质疏松杂志,2017,23(5):657-661.
[6]郁新迪,张育,李国青,等.风湿活动度预测绝经后女性类风湿关节炎患者骨密度的研究[J].中国骨质疏松杂志,2016,22(5):556-559.
[7] Leder BZ,Tsai JN,Uihlein AV,et al. Denosumab and teriparatide transitions in postmenopausal osteoporosis(the DATA-Switch study):extension of a randomised controlled trial[J]. Lancet,2015,386(9999):1147.
[8]张海林,孙惠清,倪卓民,等.绝经后妇女膝关节骨性关节炎和骨质疏松症发生率关系[J].中国骨质疏松杂志,2016,22(4):463-465.
[9]米思奇.老年女性下肢关节等速肌力与骨密度的相关性研究[J].中国骨质疏松杂志,2016,22(7):815-817.
[10]卢涛,宋清华.太极拳、步行及舞蹈锻炼对老年女性下肢肌力、骨密度及平衡能力的影响[J].中华物理医学与康复杂志,2015,37(2):124-127.
[11]潘凌,方圆,陈琳,等.简易机体功能评估和计时起走测试评估老年人肌肉功能和肌力及肌量的价值研究[J].中国全科医学,2017,20(2):150-153.
[12]郭宏焘.户外负重有氧运动结合局部肌力训练在老年骨质疏松预防中的效果研究[J].中国骨质疏松杂志,2015,21(8):941-944.
[13] Liu X D,Cai F,Liu L,et al. MicroRNA-210 is involved in the regulation of postmenopausal osteoporosis through promotion of VEGF expression and osteoblast differentiation[J]. Biol Chem,2015,396(4):339-347.
[14]程力,常九州,周卫东.绝经后2型糖尿病患者骨硬化蛋白、PINP、CTX与骨密度相关性研究[J].中国骨质疏松杂志,2017,23(7):874-878.
[15]马俊义,施振宇,史晓林.穴位贴敷疗法对绝经后骨质疏松患者血清OPG、RANKL和髋部骨密度的影响[J].中国骨质疏松杂志,2017,23(7):921-925.
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