基于MATLAB的长春花生物碱含量的分析与预测
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摘要
长春碱是一种重要的天然抗癌药物。土壤营养成分(土壤含水量,土壤PH,有机碳,全氮,全磷,速效磷,碱解氮),和激素(6-BA(6-苄氨基腺嘌呤),IAA(吲哚-3-乙酸),ABA(脱落酸)),对长春碱含量有重要影响。本文采集了这10个研究条件和长春碱含量的原始数据,并且用MATLAB中的人工神经网络和遗传算法工具箱进行分析。结果显示土壤条件中全磷含量和土壤含水量的降低有利于提高长春碱含量,土壤PH,有机碳,全氮,碱解氮含量的升高有利于提高长春碱含量,土壤中速效磷和长春碱含量的关系不明显。激素中,IAA含量的降低有利于提高长春碱含量,6-BA,ABA含量的升高有利于提高长春碱含量。
Vinblastine is an important natural anticancer drug. Soil nutrients( soil water content,soil PH,organic carbon,total nitrogen, total phosphorus, available phosphorus, alkali-hydrolyzed nitrogen), and hormones( 6-BA( 6-benzylaminoaminoadenine),IAA( indole-3-acetic acid),ABA( abscisic acid)) have important effects on the content of vinblastine. In this paper,the ten conditions and the original data of vinblastine content are collected,and the analysis is carried out by using the artificial neural network and Genetic Algorithm toolbox in MATLAB. The results showthat the decrease of total phosphorus content and soil water content is beneficial to the increase of vinblastine content. The increase of soil PH,organic carbon,total nitrogen and alkali-hydrolyzed nitrogen content is beneficial to the increase of vinblastine content. The relationship between available phosphorus and vinblastine content in soil is not obvious. In hormones,the decrease of IAA content is beneficial to the increase of vinblastine content,while the increase of 6-BA and ABA content is beneficial to the increase of vinblastine content.
Vinblastine is an important natural anticancer drug. Soil nutrients( soil water content,soil PH,organic carbon,total nitrogen, total phosphorus, available phosphorus, alkali-hydrolyzed nitrogen), and hormones( 6-BA( 6-benzylaminoaminoadenine),IAA( indole-3-acetic acid),ABA( abscisic acid)) have important effects on the content of vinblastine. In this paper,the ten conditions and the original data of vinblastine content are collected,and the analysis is carried out by using the artificial neural network and Genetic Algorithm toolbox in MATLAB. The results showthat the decrease of total phosphorus content and soil water content is beneficial to the increase of vinblastine content. The increase of soil PH,organic carbon,total nitrogen and alkali-hydrolyzed nitrogen content is beneficial to the increase of vinblastine content. The relationship between available phosphorus and vinblastine content in soil is not obvious. In hormones,the decrease of IAA content is beneficial to the increase of vinblastine content,while the increase of 6-BA and ABA content is beneficial to the increase of vinblastine content.
引文
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[2]祖元刚,罗猛,牟璠松,等.长春花生物碱成分及其药理作用研究进展[J].天然产物研究与开发,2006(2):325-329,294.
[3]华晓雨,陶爽,孙盛楠,等.植物次生代谢产物-酚类化合物的研究进展[J].生物技术通报,2017,33(12):22-29.
[4]闫秀峰,王洋,李一蒙.植物次生代谢及其与环境的关系[J].生态学报,2007,27(6):2554-2562.
[5]于源.人工神经网络在机械优化设计中的应用[J].设备管理与维修,2018(22):154-155.
[6]张德丰. MATLAB神经网络仿真与应用[M].北京:电子工业出版社,2009.
[7]沈花玉,王兆霞,高成耀,等. BP神经网络隐含层单元数的确定[J].天津理工大学学报,2008,24(5):13-15.
[8]郁磊,史峰,王辉,等. MATLAB智能算法30个案例分析[M]. 2版.北京:北京航空航天大学出版社,2012.