小儿胃炎颗粒治疗儿童胃脘痛的疗效观察
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摘要
目的探讨小儿胃炎颗粒治疗儿童胃脘痛的疗效和安全性。方法 63例胃脘痛患儿随机分成治疗组(30例)和对照组(33例)。对照组口服养胃冲剂,治疗组口服小儿胃炎颗粒,均为一日2次,每次1包。4周为一疗程,疗程结束后,观察治疗前后患儿症状变化,并与对照组比较疗效和安全性。结果治疗组与对照组儿童胃脘痛症状均得到改善(改善率分别为83.33%和36.36%),且治疗组总体疗效更为显著(P<0.05)。同时中医证候分析也显示,治疗组疗效明显优于对照组。不良反应评价组间差异无统计学意义。结论小儿胃炎颗粒治疗儿童胃脘痛疗效优于养胃冲剂,安全性好,值得进一步评价。
Objective To investigate efficacy and safety of Xiao'er Weiyan granules for treating children epigastric pain.Methods A total of 63 children epigastric pain patients were randomly divided into two groups: treatment group(30 cases) and control group(33 cases).The control group and treatment group were administered with Yangwei granules or Xiao'er Weiyan granules respectively 1 pack twice a day orally.The efficacy and safety were evaluated after 4 week treatment.Results The symptom improvement rates in the treatment group and the control group were 83.33% and 36.36%(P<0.05) respectively.The curative effect of TCM syndrome in the treatment group was better than that in control group.Conclusion The curative effect of Xiao'er Weiyan granules on treatment of children gastritis is better than that of Yangwei granules.
Objective To investigate efficacy and safety of Xiao'er Weiyan granules for treating children epigastric pain.Methods A total of 63 children epigastric pain patients were randomly divided into two groups: treatment group(30 cases) and control group(33 cases).The control group and treatment group were administered with Yangwei granules or Xiao'er Weiyan granules respectively 1 pack twice a day orally.The efficacy and safety were evaluated after 4 week treatment.Results The symptom improvement rates in the treatment group and the control group were 83.33% and 36.36%(P<0.05) respectively.The curative effect of TCM syndrome in the treatment group was better than that in control group.Conclusion The curative effect of Xiao'er Weiyan granules on treatment of children gastritis is better than that of Yangwei granules.
引文
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[2]缪京翔.温胆汤加减治疗慢性胃炎的疗效观察[J].光明中医,2010,8(25):1412-1414.
[3]白小秋.中药治疗胃脘痛体会[J].中国现代药物应用,2012,6(6):17-18.
[4]杨金池.从肝脾论治胃脘痛109例[J].湖北中医杂志,2002,24(12):38.
[5]马清钧,王淑玲.临床实用中药学[M].江西:江西科学技术出版社,2002:10.
[6]吴艳玲,朴惠善.蒲公英的药理研究进展[J].时珍国医国药,2004,3(4):519-520.
[7]徐国钧,徐珞珊.常用中药材品种整理与质量研究[M].福建:福建科学技术出版社,1997:241.
[8]陈红,刘传玉,李承晏.青皮的化学及药理作用研究进展[J].中草药,2001,11(32):1050-1052.
[9]贺凯,高建莉,赵光树.延胡索化学成分、药理作用及质量控制研究进展[J].中草药,2007,12(38):1909-1911.
[10]赵永娟,吉中强,张向农,等.生半夏、姜半夏对水貂呕吐作用的影响研究[J].中国中药杂志,2005,4(30):277-279.