二甲双胍联合消渴康颗粒治疗2型糖尿病临床疗效分析

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英文篇名：Clinical Curative Effect Analysis of Using Melbine Combined with Xiaokekang Particles to Cure Type 2 Diabetes 作者：王炼石 英文作者：Wang Lianshi;Nanjiang County Hospital of TCM ombined with WM Department of Gastroenterology; 关键词：2型糖尿病 ; 二甲双胍 ; 消渴康颗粒 英文关键词：Type 2 diabetes;;Melbine;;Xiaokekang particles 中文刊名：YXYY 英文刊名：Journal of Imaging Research and Medical Applications 机构：四川省巴中市南江县中医医院内科; 出版日期：2018-05-01 出版单位：影像研究与医学应用 年：2018 期：v.2 语种：中文; 页：YXYY201809010 页数：3 CN：09 ISSN：13-1424/R 分类号：27-29

摘要

目的:了解2型糖尿病患者采用二甲双胍与消渴康颗粒联合治疗的临床疗效。方法:将120例2016年5月—2017年10月期间确诊为2型糖尿病的患者以随机分配法平均划分为实验组与对照组。对照组采用二甲双胍进行治疗,实验组采用二甲双胍联合消渴康颗粒进行治疗。对治疗期间FPG(空腹血糖)和2h PG(餐后2h血糖)与Hb A1c(糖化血红蛋白)及HOMA-β(胰岛β细胞功能指数)等四项指标,临床症状变化和不良反应及临床疗效等相关情况予以检测与记录分析。结果:治疗后患者临床症状与体征均得到一定程度改善,虽发生不良反应,但症状在停药后均消失。治疗总有效率方面,对照组为73.3%,实验组为95.0%,P<0.05,差异具有统计学意义。结论:二甲双胍与消渴康颗粒联合的治疗方案,可有效提高2型糖尿病治疗效果,临床应用价值较好。
        Objective To know about the clinical curative effects of using melbine combined with Xiaokekang particles to cure patients with type 2 diabetes. Methods 12 patients who were diagnosed with type 2 diabetes from May 2015 to October 2017 were divided into the experiment and control groups by using distribution method at random. Patients in the control group were treated by melbine, while patients in the experiment group were treated by using melbine combined with Xiaokekang particles. During the treatment process, FPG, 2 h PG, Hb Alc and HOMA-β, clinical symptom changes,, untoward effects and clinical effects were detected and conducted recording analysis. Results After treatment, patients' clinical symptoms and signs were improved to some extent. Though there were untoward effects, these symptoms disappeared after drug withdrawal. The total effective rate of treatment in the control and experiment groups was 73.3% and 95.0%, respectively, p<0.05. There was the statistical difference. Conclusions The therapeutic schedule of melbine combined with Xiaokekang particles could effectively improve therapeutic effects of type 2 diabetes, showing the excellent clinical application value.

引文

[1]李长鑫.不同方案治疗难治性2型糖尿病的临床疗效、安全性及经济学比较[J].医学理论与实践,2017,30(22):3338-3340.
    [2]李军,苏凤全,张义军.二甲双胍联合消渴康颗粒治疗初发2型糖尿病临床疗效观察[J/OL].中国妇幼健康研究,2017(S2):108[2017-12-18].
    [3]赵昱,牛晓亚,许有慧,邹蔚萌,刘亚男.消渴康颗粒联合二甲双胍治疗2型糖尿病随机平行对照研究[J].实用中医内科杂志,2017,31(01):42-44.
    [4]陈丹玲,王淑芳.二甲双胍临床应用新进展[J].国际内科学杂志,2008,35(10):578-581.
    [5]刘美艳.瑞格列奈联合二甲双胍治疗2型糖尿病临床疗效观察[J].临床合理用药杂志,2013,6(36):21-22.
    [6]张磊,洪兵.消渴康颗粒联合盐酸吡咯列酮片治疗2型糖尿病阴虚热盛型临床观察[J].辽宁中医药大学学报,2014,16(12):117-119.