补阳还五汤对髋关节置换术后气虚血瘀证患者血栓前状态的影响
摘要
目的分析补阳还五汤加减在髋关节置换术后气虚血瘀证患者血栓前状态治疗中的应用效果。方法用数字随机表分组法将2016年5月—2018年3月接受髋关节置换术,并且术后出现血栓前状态(气虚血瘀证)的60例患者分为30例/组。对照组进行常规性治疗,观察组进行常规性治疗+补阳还五汤加减口服治疗。对比2组血液流变学指标、凝血指标及术后下肢深静脉血栓形成率。结果术后10 d,与对照组相比观察组红细胞变形指数(0. 66±0. 10)更高,血小板电泳时间(17. 52±1. 63) s更短,血浆黏度(1. 29±0. 48) mPa·s更低,D-二聚体(259. 63±24. 15)μg/L、纤维蛋白原(2. 62±0. 71) g/L 2项凝血指标水平及术后半个月下肢深静脉血栓形成率(3. 33%)更低(P <0. 05)。结论在髋关节置换术后气虚血瘀证患者血栓前状态治疗中应用补阳还五汤加减疗效确切。
引文
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[2]付之军.加味补阳还五汤治疗气虚血瘀型脑血栓的临床应用价值[J].中国继续医学教育,2015,7(10):255-256.
[3]马松涛,邱庆虎,王科,等.补阳还五汤加减口服对髋关节置换术后气虚血瘀证患者血栓前状态的影响[J].中国中医骨伤科杂志,2018,26(4):36-39.
[4]侯军其.补阳还五汤对老年股骨粗隆间骨折防旋股骨近端髓内钉术后血栓相关并发症的影响[J].血栓与止血学,2017,23(5):778-779.
[5]VOGL M,LEIDL R,PLOETZ W,et al.Comparison of pre-and postoperative health-related quality of life and length of stay after primary total hip replacement in matched English and German patient cohorts[J].Qual Life Res,2015,24(2):513-520.
[6]王现营.加味补阳还五汤治疗急性脑血栓形成的临床观察[J].光明中医,2018,33(16):2394-2396.
[7]张燕文,戴勇,张威莲.低分子肝素钙联合血栓通注射液对髋关节置换术后下肢深静脉血栓的临床效果[J].中医临床研究,2018,10(29):80-82.
[8]LOESCHNER K,HARRINGTON C F,KEARNEY JL,et al.Feasibility of asymmetric flow field-flow fractionation coupled to ICP-MS for the characterization of wear metal particles and metalloproteins in biofluids from hip replacement patients[J].Anal Bioanal Chem,2015,407(16):4541-4554.
[9]马璐璐,虞雪融,黄宇光.快速血栓弹力图监测关节置换术患者围术期的凝血功能[J].中国输血杂志,2015,28(6):655-657.
[10]徐怡娜,袁海军,胡益飞.血栓弹力图评价不同麻醉方式对全髋置换术围手术期凝血功能的影响[J].浙江实用医学,2017,22(2):118-119,123.
[11]刘嵘,郭小燕.加味补阳还五汤联合康复训练治疗脑卒中后肩手综合征60例[J].河南中医,2016,36(2):245-246.