CysC联合尿微量白蛋白/肌酐比值在糖尿病肾病早期诊断中的价值
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摘要
目的探讨CysC联合尿微量白蛋白/肌酐比值在糖尿病肾病早期诊断中的价值。方法选取2016年9月—2018年9月该院收治的69例DN患者(A组)与69例单纯糖尿病患者(B组)进行Cys-c与mALB/Cr检测,并与同期在该院进行体检的67名健康人进行对比。结果 A组Cys-c与mALB/Cr水平显著高于B组和对照组(P<0.05);mALB/Cr与Cys-c联合阳性率91.3%显著高于单项Cys-c检测和mALB/Cr检测(P<0.05)。结论 CysC与mALB/Cr联合检测提高了单项检测的准确性和敏感性,对DN的早期发现、诊断、治疗有重要价值。
Objective To investigate the value of CysC combined with urinary microalbumin/creatinine ratio in the early diagnosis of diabetic nephropathy. Methods 69 patients with DN(group A) and 69 patients with simple diabetes(group B) admitted to our hospital from September 2016 to September 2018 were enrolled in the study of Cys-c and mALB/Cr. A total of 67 healthy people were examined for physical examination. Results The levels of Cys-c and mALB/Cr in group A were significantly higher than those in group B and control group(P<0.05). The positive rate of combined ratio of mALB/Cr and Cys-c was 91.3% higher than that of single Cys-c and mALB/Cr(P <0.05). Conclusion The combination of CysC and mALB/Cr improves the accuracy and sensitivity of single detection, and is of great value for the early detection, diagnosis and treatment of DN.
Objective To investigate the value of CysC combined with urinary microalbumin/creatinine ratio in the early diagnosis of diabetic nephropathy. Methods 69 patients with DN(group A) and 69 patients with simple diabetes(group B) admitted to our hospital from September 2016 to September 2018 were enrolled in the study of Cys-c and mALB/Cr. A total of 67 healthy people were examined for physical examination. Results The levels of Cys-c and mALB/Cr in group A were significantly higher than those in group B and control group(P<0.05). The positive rate of combined ratio of mALB/Cr and Cys-c was 91.3% higher than that of single Cys-c and mALB/Cr(P <0.05). Conclusion The combination of CysC and mALB/Cr improves the accuracy and sensitivity of single detection, and is of great value for the early detection, diagnosis and treatment of DN.
引文
[1]王素霞.血清胱抑素c联合检测尿微量蛋白在糖尿病肾病早期诊断中的应用[J].医药,2017,3(1):312.
[2]张韵倩,徐丛荣,池飞燕.血清胱抑素C、β-2微球蛋白和尿微量白蛋白/肌酐比值在早期2型糖尿病肾病中的诊断价值[J].医学理论与实践,2017,30(4):583.
[3]郑莹莹,闫卫利.血清胱抑素C、β_2-微球蛋白和尿微量蛋白/肌酐比值联合检测在早期2型糖尿病肾病诊断中的应用[J].医疗装备,2018,15(8):165-166.
[4]姜海华,王金英,张翔,等.血清胱抑素C和尿微量白蛋白/肌酐比值在糖尿病肾病早期临床诊断[J].中国实用医刊,2016,43(11):70.
[5]张华,金钧.尿微量白蛋白/肌酐比值联合血清胱抑素C在糖尿病肾病早期诊断中的临床价值[J].医学检验与临床,2017,28(5):55-57.
[6]阳小芳.胱抑素C和尿微量白蛋白肌酐比值对糖尿病肾病早期损害的临床意义[J].世界最新医学信息文摘,2017,24(53):214.
[7]路继成,任丽霞.血清胱抑素C、尿微量白蛋白与尿肌酐比值对糖尿病肾病的诊断价值[J].临床合理用药杂志,2017,10(20):97-98.
[8]刘洪莉.血清胱抑素C与尿微量白蛋白/肌酐比值在2型糖尿病肾病早期诊断中的应用价值[J].河南医学研究,2017,21(5):852-853.
[2]张韵倩,徐丛荣,池飞燕.血清胱抑素C、β-2微球蛋白和尿微量白蛋白/肌酐比值在早期2型糖尿病肾病中的诊断价值[J].医学理论与实践,2017,30(4):583.
[3]郑莹莹,闫卫利.血清胱抑素C、β_2-微球蛋白和尿微量蛋白/肌酐比值联合检测在早期2型糖尿病肾病诊断中的应用[J].医疗装备,2018,15(8):165-166.
[4]姜海华,王金英,张翔,等.血清胱抑素C和尿微量白蛋白/肌酐比值在糖尿病肾病早期临床诊断[J].中国实用医刊,2016,43(11):70.
[5]张华,金钧.尿微量白蛋白/肌酐比值联合血清胱抑素C在糖尿病肾病早期诊断中的临床价值[J].医学检验与临床,2017,28(5):55-57.
[6]阳小芳.胱抑素C和尿微量白蛋白肌酐比值对糖尿病肾病早期损害的临床意义[J].世界最新医学信息文摘,2017,24(53):214.
[7]路继成,任丽霞.血清胱抑素C、尿微量白蛋白与尿肌酐比值对糖尿病肾病的诊断价值[J].临床合理用药杂志,2017,10(20):97-98.
[8]刘洪莉.血清胱抑素C与尿微量白蛋白/肌酐比值在2型糖尿病肾病早期诊断中的应用价值[J].河南医学研究,2017,21(5):852-853.