真菌性外耳道炎的临床研究
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摘要
目的:为了提高对真菌性外耳道炎的认识,并找到一种合理的治疗方法,减少其复发。方法:对167例患者耳内分泌物行细菌及真菌培养,选用两种常用的抗真菌药物派瑞松及达克宁进行治疗,每一组内再分成患者自行涂抹药物组及耳内镜下外耳道给药组,分别比较两种药物及两种给药方式的有效率。结果:培养出191株致病真菌中,曲霉菌145例,酵母菌38例,念珠菌8例;共有24例患者同时培养出致病细菌;内镜下给药组有效率明显高于患者自行涂抹药物组,派瑞松组有效率高于达克宁组。结论:真菌性外耳道炎主要的致病真菌是曲霉菌和酵母菌,耳内镜下外耳道填塞派瑞松是治疗真菌性外耳道炎简单、有效、依从性好的方法。
Objective: To improve the understanding of otitis external mycotica, and find a more reasonable treatment and reduce its recurrence. Methods: 167 patients of otitis external mycotica had the bacterial and fungal cultures,and treated with two kinds of commonly used antifungal agents, Pevisone and Dekening. The patients were treated by two different mode of administration in each group: Patient self-coated drugs and Endoscopic administration by doctor, and then to compare the efficacy of the two drugs and the two modes of administration. Results: Among the 191 pathogenic fungi, 145 cases of Aspergillus, 38 cases of Yeast and 8 cases of Candida were isolated. 24 patients were cultured with pathogenic bacteria. The effective rate of Endoscopic administration was higher than Patient self-coated drugs, and Pevisone was more effective than Dekening. Conclusion: The main pathogenic fungi of otitis external mycotica is Aspergillus and Yeast, and Endoscopic administration with Pevisone is a simple, effective and reliable method for the treatment of otitis external mycotica.
Objective: To improve the understanding of otitis external mycotica, and find a more reasonable treatment and reduce its recurrence. Methods: 167 patients of otitis external mycotica had the bacterial and fungal cultures,and treated with two kinds of commonly used antifungal agents, Pevisone and Dekening. The patients were treated by two different mode of administration in each group: Patient self-coated drugs and Endoscopic administration by doctor, and then to compare the efficacy of the two drugs and the two modes of administration. Results: Among the 191 pathogenic fungi, 145 cases of Aspergillus, 38 cases of Yeast and 8 cases of Candida were isolated. 24 patients were cultured with pathogenic bacteria. The effective rate of Endoscopic administration was higher than Patient self-coated drugs, and Pevisone was more effective than Dekening. Conclusion: The main pathogenic fungi of otitis external mycotica is Aspergillus and Yeast, and Endoscopic administration with Pevisone is a simple, effective and reliable method for the treatment of otitis external mycotica.
引文
[1]江刚,刘永红.真菌性外耳道炎致鼓膜穿孔18例报告[J].临床耳鼻咽喉科杂志,2003,17(7):435.
[2]闫欣荣.耳内镜下外耳道冲洗联合氟康唑液治疗外耳道真菌病疗效观察[J].西藏医药杂志,2013,35(3):16~17.
[3]张子平,程波.1015例眼部、鼻部及耳部真菌感染的病原学分析[J].福建医药杂志,2004,26(5):37~38.
[4]Abou-halawa A.S.MD,et al.Otomycosis with Perforated Tympanic Membrane:Self medication with Topical Antifungal Solution versus Medicated Ear Wick.International Journal of Health Sciences,Qassim University,2012,6(1):73~77.
[5]黄选兆,汪吉宝,孔维佳.实用耳鼻咽喉头颈外科学[M].第2版,北京:人民卫生出版社,2008:1169~1170.
[2]闫欣荣.耳内镜下外耳道冲洗联合氟康唑液治疗外耳道真菌病疗效观察[J].西藏医药杂志,2013,35(3):16~17.
[3]张子平,程波.1015例眼部、鼻部及耳部真菌感染的病原学分析[J].福建医药杂志,2004,26(5):37~38.
[4]Abou-halawa A.S.MD,et al.Otomycosis with Perforated Tympanic Membrane:Self medication with Topical Antifungal Solution versus Medicated Ear Wick.International Journal of Health Sciences,Qassim University,2012,6(1):73~77.
[5]黄选兆,汪吉宝,孔维佳.实用耳鼻咽喉头颈外科学[M].第2版,北京:人民卫生出版社,2008:1169~1170.