开放二孩政策实施后二胎妊娠期并发症的危险因素分析
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摘要
目的探讨开放二孩政策实施后二胎孕妇妊娠期并发症的危险因素,以期降低不良妊娠结局的发生率。方法选取2016年11月～2017年4月我院收治的存在妊娠期并发症的二胎孕妇102例设为病例组,另选无妊娠期并发症的二胎孕妇108例设为对照组,收集产妇的一般资料及可能的危险因素,对有妊娠并发症的孕妇资料进行单因素分析和多因素非条件Logistic回归分析。结果单因素分析结果显示:病例组不良妊娠史、与一胎间隔时间长、无孕前检查及孕期营养指导的发生率较对照组高,差异有统计学意义(P<0.05);Logistic回归分析显示:与一胎间隔时间长、无孕前检查及孕期营养指导为二胎妊娠期并发症的危险因素。结论与一胎间隔时间、孕期营养指导及孕前检查与妊娠期并发症的发生有关。
Objective To investigate the risk factors of gestational complications in pregnant women with secondary pregnancy after the implementation of the open two-child policy, with a view to reducing the incidence of adverse pregnancy outcomes. Methods From November 2016 to April 2017,102 pregnant women with gestational complications admitted to our hospital were enrolled as a case group. 108 pregnant women with no gestational complications were selected as the control group. Information on maternal and possible risk factors, single factor analysis and multivariate unconditional logistic regression analysis of pregnant women with pregnancy complications. Results Single factor analysis showed that the incidence of adverse pregnancy history, long interval between one child, non-pregnancy check and nutrition guidance during pregnancy was higher than that of the control group, the difference was statistically significant(P<0.05); Logistic regression analysis showed : Long interval between one child, no prepregnancy check and nutrition guidance during pregnancy are risk factors for complications of second trimester pregnancy. Conclusion It is related to the interval between one child, nutrition guidance during pregnancy and pre-pregnancy examination and complications during pregnancy.
Objective To investigate the risk factors of gestational complications in pregnant women with secondary pregnancy after the implementation of the open two-child policy, with a view to reducing the incidence of adverse pregnancy outcomes. Methods From November 2016 to April 2017,102 pregnant women with gestational complications admitted to our hospital were enrolled as a case group. 108 pregnant women with no gestational complications were selected as the control group. Information on maternal and possible risk factors, single factor analysis and multivariate unconditional logistic regression analysis of pregnant women with pregnancy complications. Results Single factor analysis showed that the incidence of adverse pregnancy history, long interval between one child, non-pregnancy check and nutrition guidance during pregnancy was higher than that of the control group, the difference was statistically significant(P<0.05); Logistic regression analysis showed : Long interval between one child, no prepregnancy check and nutrition guidance during pregnancy are risk factors for complications of second trimester pregnancy. Conclusion It is related to the interval between one child, nutrition guidance during pregnancy and pre-pregnancy examination and complications during pregnancy.
引文
[1]高玉东.妊娠期糖尿病两种诊断标准治疗后对孕产妇及产儿的不同妊娠结局影响[J].中国妇幼保健,2015,30(3):360-362.
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[3]Lee KW,Ching SM,Ramachandran V,et al.Prevalence and risk factors of gestational diabetes mellitus in Asia:a systematic review and meta-analysis[J].BMC Pregnancy and Childbirth,2018,18(1):494.
[4]宋汶珂,唐彩霞,黄彤辉.二胎妊娠的妊娠并发症与影响因素分析[J].妇儿医学,2017,11(12):145.
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[10]冯永亮,彭婷婷,王芳,等.妊娠期高血压疾病对疾出生结局的影响及相关因素[J].中华病控制杂志,2014,18(2):131-134.
[11]丛云凤,孙爽,管惊雷,等.妊娠期高血压疾病相关因素分析[J].中国妇幼保健,2011,17(26):2573-2576.
[12]高雯,李卫芹,吕凤军,等.妊娠期糖尿病的影响因素及围生结局的研究分析[J].国际妇产科学杂志,2015,42(4):381-383.
[13]黄莉,张莉,李洪艳,等.孕产妇不良妊娠结局危险因素的巢式病例对照研究[J].中国现代医学杂志,2015(9):106-109.
[14]李琼珊.妊娠期糖尿病筛查与其高危因素的临床分析[J].实用糖尿病杂志,2008,2(2):61-63.
[2]Correa PJ,Vargas JF,Sen S,et al.Prediction of gestational diabetes early in pregnancy:targeting the long-term complications[J].Gynecol Obstet Invest,2014,77(3)145-149.
[3]Lee KW,Ching SM,Ramachandran V,et al.Prevalence and risk factors of gestational diabetes mellitus in Asia:a systematic review and meta-analysis[J].BMC Pregnancy and Childbirth,2018,18(1):494.
[4]宋汶珂,唐彩霞,黄彤辉.二胎妊娠的妊娠并发症与影响因素分析[J].妇儿医学,2017,11(12):145.
[5]蒋歆昶,张旭,杨伟伟,等.生育政策调整对二胎孕妇高危妊娠及其妊娠结局的影响[J].中国医学创新,2017,14(28):63-65.
[6]康楚云,高燕秋,宋莉,等.生育政策调整对助产医院分娩量及产妇构成的影响[J].人口研究,2015,39(6):85-93.
[7]贾朝霞,黄爱群,赵薇,等.调整生育政策对北京市产科资源的影响[J].中国全科医学,2016,19(21):2542-2546.
[8]Kurabayashi T,Mizunuma H,Kubota T,et al.Pregnancy-induced hypertension is associated with maternal history and a risk of cardiovascular disease in later life:Japanese cross-sectional study[J].Maturitas,2013,75(3):227-231.
[9]徐志芳,杨昱,陈丽莉,等.妊娠期糖尿病发病机制及其对母婴的影响[J].中国临床医生杂志,2015,43(8):26-29.
[10]冯永亮,彭婷婷,王芳,等.妊娠期高血压疾病对疾出生结局的影响及相关因素[J].中华病控制杂志,2014,18(2):131-134.
[11]丛云凤,孙爽,管惊雷,等.妊娠期高血压疾病相关因素分析[J].中国妇幼保健,2011,17(26):2573-2576.
[12]高雯,李卫芹,吕凤军,等.妊娠期糖尿病的影响因素及围生结局的研究分析[J].国际妇产科学杂志,2015,42(4):381-383.
[13]黄莉,张莉,李洪艳,等.孕产妇不良妊娠结局危险因素的巢式病例对照研究[J].中国现代医学杂志,2015(9):106-109.
[14]李琼珊.妊娠期糖尿病筛查与其高危因素的临床分析[J].实用糖尿病杂志,2008,2(2):61-63.