松属植物的化学成分及生物活性研究进展
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摘要
松属植物中普遍含有挥发油类、萜类、木质素类和黄酮类等化学成分,且有较好的抗氧化活性、抗衰老活性、抗肿瘤和抑菌作用.对松属类植物的化学成分及生物活性的研究进展进行了综述,以期对该属植物的实际应用价值进行开发利用.
Pinus showed that the major chemical constituents are volatile oils,terpenoids,lignans,flavonoids and so on,and the bioactivities were showed to be antioxidant activity,anti-aging activity,antitumor and antifungal activity.Summarized the research progress of the chemical component and biological activity of Pinus.Accordingly,the practical application value of Pinus will be developed and utilized.
Pinus showed that the major chemical constituents are volatile oils,terpenoids,lignans,flavonoids and so on,and the bioactivities were showed to be antioxidant activity,anti-aging activity,antitumor and antifungal activity.Summarized the research progress of the chemical component and biological activity of Pinus.Accordingly,the practical application value of Pinus will be developed and utilized.
引文
[1]李丹苏.松针抗菌物的分离提取及其活性研究[D].长春:吉林农业大学,2015
[2]邢有权,谢静芝.樟子松球果挥发油成分研究[J].林产化学与工业,1992(3):231-234
[3]杨鑫,邱建伟,张华,等.松属植物化学成分及生物活性的研究进展[J].中药材,2007,30(7):878-883
[4]江苏新医学院.中药大辞典(下册)[M].上海:上海人民出版社,1977
[5]胡丰林,陆瑞利.松针的利用价值分析[J].生物学杂志,1996(2):25-26
[6]李寅珊,刘光明,李冬梅.松属植物化学成分及抗肿瘤活性研究进展[J].时珍国医国药,2012,23(3):726-727
[7]张蓉.樟子松针叶活性成分研究[D].天津:天津大学,2005
[8]王巍,王晓华,尹江峰,等.马尾松松针的黄酮类化学成分的分离鉴定[J].中国医院药学杂志,2008,28(7):549-552
[9]刘敏莉,刘佳,李江楠,等.油松·樟子松松针挥发油化学成分研究[J].安徽农业科学,2011,39(25):15420-15421
[10]马聪,刘佳佳,杨栋梁,等.湿地松树皮挥发油中的萜类化学成分分析[J].广东化工,2007,34(3):81-82
[11]陈红梅,叶文峰,管月清,等.湿地松针叶挥发油化学成分研究[J].江西师范大学学报:自然科学版,2001,13(2):10-12
[12]张蓉,段宏泉,姚智,等.樟子松针叶中二萜类成分研究[J].中国中药杂志,2006,31(23):1956-1959
[13]Zinkel D F,Magee T V,Walter J.Major resin acids of Pinus nigra needles[J].Phytochemistry,1985,24(6):1273-1277
[14]Carreras C R,Rossomando P C,Giordano O S.Ent-labdanes in eupatorium buniifolium[J].Phytochemistry,1998,48(6):1031-1034
[15]Ayer W A,Migaj B S.Acids from blue-stain diseased lodgepole pine[J].Canadian Journal of Botany,1989,67(5):1426-1428
[16]Torbj?rn Norin,Stefen Sundin,Olof Theander,et al.The Constituents of Conifer Needles IV Dehydropinifolic Acid,a Diterpene Acid from the Needles of Pinus sylvestris L[J].Acta Chemica Scandinavica,1971,25(2):607-610
[17]Ekman R,Sjoeholm R.Isoabienol,the principal diterpene alcohol in Pinus sylvestris needles[J].Acta Chemica Scandinavica,1977,31b(10):921-922
[18]杨鑫,邱建伟,张华,等.松属植物化学成分及生物活性的研究进展[J].中药材,2007,30(7):878-883
[19]申长茂,段文贵,岑波,等.广西产马尾松与湿地松针叶精油化学成分的比较[J].色谱,2006,24(6):619-624
[20]刘东彦,石晓峰,李冲,等.雪松松针黄酮类化学成分的研究[J].中草药,2011,42(4):631-633
[21]倪刚,张庆建,郑重飞,等.华桑茎皮的化学成分研究[J].中草药,2010,41(2):191-195
[22]Zhang Y S,Zhang Q Y B,Li-Ying L I,et al.Chemical Constituents from Ampelopsis grossedentata[J].Journal of Chinese Pharmaceutical Sciences,2006,15(4):211-214
[23]Zhang Y,Que S,Yang X,et al.Isolation and identification of metabolites from dihydromyricetin[J].Magnetic Resonance in Chemistry,2007,45(11):909
[24]Popoff T.The constitutents of conifer needles VI Phenolic glycosides from Pinus sylvestris[J].Acta Chem Scand B,1977,31(4):329-337
[25]Lundgren L N,Shen Z,Theander O.Chem Inform Abstract:THE CONSTITUENTS OF CONIFER NEEDLES.PART 12 DILIGNOL GLYCOSIDES FROM PINUS MASSONIANA LAMB[J].Acta Chemica Scandinavica,1985,39(35):241-248
[26]毕跃峰,郑晓珂,刘宏民,等.马尾松松针化学成分的研究[J].药学学报,2001,36(11):832-835
[27]Kawanishi K,Uhara Y,Hashimoto Y.Neolignans of Virola carinata,bark[J].Phytochemistry,1982,21(11):2725-2728
[28]Feng W S,Zheng X K,Wang Y Z,et al.Isolation and structure identification of lignans from pine needles of Pinus massonianaLamb[J].Yao Xue Xue Bao,2002,38(12):626-629
[29]毕跃峰,郑晓珂,张勇忠,等.马尾松松针中木脂素苷的分离与结构鉴定[J].药学学报,2002,37(8):626-629
[30]周应军,徐绥绪,孙启时,等.巴东栎中的黄酮类成分[J].沈阳药科大学学报,2000,17(4):263-266
[31]邓勋,宋瑞清,宋小双,等.高效木霉菌株对樟子松枯梢病的抑菌机理[J].中南林业科技大学学报,2012,32(11):21-27
[32]钟胜佳,高岩,袁久志,等.油松松针中黄酮类成分的分离与鉴定[J].沈阳药科大学学报,2009,26(11):889-892
[33]Liu H,Orjala J,Sticher O,et al.Acylated flavonol glycosides from leaves of Stenochlaena palustris[J].Journal of Natural Products,1999,62(1):70
[34]Popoff T.The constitutents of conifer needles.VI Phenolic glycosides from Pinus sylvestris[J].Acta Chem Scand B,1977,31(4):329-337
[35]Pelter A,Ward R S,Gray T I.The carbon-13 nuclear magnetic resonance spectra of flavonoids and related compounds[J].J Chem Soc Perkin,1977,8(11):2475-2483
[36]Taner G,Aydin S,Ayta?Z,et al.Genotoxic and antigenotoxic effects of pycnogenol in human lymphocytes assessed by the alkaline Comet assay[J].Toxicology Letters,2011,205(205):S111
[37]张宇,王莉,傅宇明,等.樟子松松塔抗氧化及抗炎作用研究[J].时珍国医国药,2010,21(6):1549-1549
[38]王焰山,张自文,黄晓萍,等.松针提取液对实验性高脂血症及脂质过氧化作用的影响[J].北京中医药大学学报,2001,24(2):35-36
[39]苏晓雨,王振宇.红松种子壳多酚物质的提取及抗氧化特性[J].农业工程学报,2009(s1):198-203
[40]李海涛,张良,盛玉青,等.松树皮原花青素的抗肿瘤作用研究[J].南京中医药大学学报,2007,23(1):43-45
[41]Qiang,Wang,Zhang,et al.Two new antitumor diterpenes from Pinus sylvestris[J].中国化学快报:英文版,2008,19(2):187-189
[42]刘光明,吕永俊,李好枝,等.云南松松塔中抗HIV活性成分的研究初报[J].大理大学学报,2009,8(2):69-71
[43]刘光明,吕永俊,周萍,等.松属植物的松塔、松子壳药用开发[J].大理大学学报,2007,6(12):77-80
[44]吕小满,胡艳芬,刘光明,等.松塔化学成分及生物活性的研究进展[J].医学综述,2010,16(7):1071-1073
[45]El-Ghorab A,El-Massry K,Shaaban H.Effect of Drying on the Chemical Composition of the Egyptian Cupressus macrocarpa(Hartw.ex Gordon)Essential Oils and their Biological Characteristics[J].Journal of Essential Oil Bearing Plants,2007,10(5):399-411
[46]肖靖萍,任宇红.松针抑菌作用的研究[J].食品科学,1994(2):52-54
[47]郭阿君,王志英,邹丽.樟子松挥发性有机物释放动态及其抑菌作用[J].东北林业大学学报,2014(4):115-118
[2]邢有权,谢静芝.樟子松球果挥发油成分研究[J].林产化学与工业,1992(3):231-234
[3]杨鑫,邱建伟,张华,等.松属植物化学成分及生物活性的研究进展[J].中药材,2007,30(7):878-883
[4]江苏新医学院.中药大辞典(下册)[M].上海:上海人民出版社,1977
[5]胡丰林,陆瑞利.松针的利用价值分析[J].生物学杂志,1996(2):25-26
[6]李寅珊,刘光明,李冬梅.松属植物化学成分及抗肿瘤活性研究进展[J].时珍国医国药,2012,23(3):726-727
[7]张蓉.樟子松针叶活性成分研究[D].天津:天津大学,2005
[8]王巍,王晓华,尹江峰,等.马尾松松针的黄酮类化学成分的分离鉴定[J].中国医院药学杂志,2008,28(7):549-552
[9]刘敏莉,刘佳,李江楠,等.油松·樟子松松针挥发油化学成分研究[J].安徽农业科学,2011,39(25):15420-15421
[10]马聪,刘佳佳,杨栋梁,等.湿地松树皮挥发油中的萜类化学成分分析[J].广东化工,2007,34(3):81-82
[11]陈红梅,叶文峰,管月清,等.湿地松针叶挥发油化学成分研究[J].江西师范大学学报:自然科学版,2001,13(2):10-12
[12]张蓉,段宏泉,姚智,等.樟子松针叶中二萜类成分研究[J].中国中药杂志,2006,31(23):1956-1959
[13]Zinkel D F,Magee T V,Walter J.Major resin acids of Pinus nigra needles[J].Phytochemistry,1985,24(6):1273-1277
[14]Carreras C R,Rossomando P C,Giordano O S.Ent-labdanes in eupatorium buniifolium[J].Phytochemistry,1998,48(6):1031-1034
[15]Ayer W A,Migaj B S.Acids from blue-stain diseased lodgepole pine[J].Canadian Journal of Botany,1989,67(5):1426-1428
[16]Torbj?rn Norin,Stefen Sundin,Olof Theander,et al.The Constituents of Conifer Needles IV Dehydropinifolic Acid,a Diterpene Acid from the Needles of Pinus sylvestris L[J].Acta Chemica Scandinavica,1971,25(2):607-610
[17]Ekman R,Sjoeholm R.Isoabienol,the principal diterpene alcohol in Pinus sylvestris needles[J].Acta Chemica Scandinavica,1977,31b(10):921-922
[18]杨鑫,邱建伟,张华,等.松属植物化学成分及生物活性的研究进展[J].中药材,2007,30(7):878-883
[19]申长茂,段文贵,岑波,等.广西产马尾松与湿地松针叶精油化学成分的比较[J].色谱,2006,24(6):619-624
[20]刘东彦,石晓峰,李冲,等.雪松松针黄酮类化学成分的研究[J].中草药,2011,42(4):631-633
[21]倪刚,张庆建,郑重飞,等.华桑茎皮的化学成分研究[J].中草药,2010,41(2):191-195
[22]Zhang Y S,Zhang Q Y B,Li-Ying L I,et al.Chemical Constituents from Ampelopsis grossedentata[J].Journal of Chinese Pharmaceutical Sciences,2006,15(4):211-214
[23]Zhang Y,Que S,Yang X,et al.Isolation and identification of metabolites from dihydromyricetin[J].Magnetic Resonance in Chemistry,2007,45(11):909
[24]Popoff T.The constitutents of conifer needles VI Phenolic glycosides from Pinus sylvestris[J].Acta Chem Scand B,1977,31(4):329-337
[25]Lundgren L N,Shen Z,Theander O.Chem Inform Abstract:THE CONSTITUENTS OF CONIFER NEEDLES.PART 12 DILIGNOL GLYCOSIDES FROM PINUS MASSONIANA LAMB[J].Acta Chemica Scandinavica,1985,39(35):241-248
[26]毕跃峰,郑晓珂,刘宏民,等.马尾松松针化学成分的研究[J].药学学报,2001,36(11):832-835
[27]Kawanishi K,Uhara Y,Hashimoto Y.Neolignans of Virola carinata,bark[J].Phytochemistry,1982,21(11):2725-2728
[28]Feng W S,Zheng X K,Wang Y Z,et al.Isolation and structure identification of lignans from pine needles of Pinus massonianaLamb[J].Yao Xue Xue Bao,2002,38(12):626-629
[29]毕跃峰,郑晓珂,张勇忠,等.马尾松松针中木脂素苷的分离与结构鉴定[J].药学学报,2002,37(8):626-629
[30]周应军,徐绥绪,孙启时,等.巴东栎中的黄酮类成分[J].沈阳药科大学学报,2000,17(4):263-266
[31]邓勋,宋瑞清,宋小双,等.高效木霉菌株对樟子松枯梢病的抑菌机理[J].中南林业科技大学学报,2012,32(11):21-27
[32]钟胜佳,高岩,袁久志,等.油松松针中黄酮类成分的分离与鉴定[J].沈阳药科大学学报,2009,26(11):889-892
[33]Liu H,Orjala J,Sticher O,et al.Acylated flavonol glycosides from leaves of Stenochlaena palustris[J].Journal of Natural Products,1999,62(1):70
[34]Popoff T.The constitutents of conifer needles.VI Phenolic glycosides from Pinus sylvestris[J].Acta Chem Scand B,1977,31(4):329-337
[35]Pelter A,Ward R S,Gray T I.The carbon-13 nuclear magnetic resonance spectra of flavonoids and related compounds[J].J Chem Soc Perkin,1977,8(11):2475-2483
[36]Taner G,Aydin S,Ayta?Z,et al.Genotoxic and antigenotoxic effects of pycnogenol in human lymphocytes assessed by the alkaline Comet assay[J].Toxicology Letters,2011,205(205):S111
[37]张宇,王莉,傅宇明,等.樟子松松塔抗氧化及抗炎作用研究[J].时珍国医国药,2010,21(6):1549-1549
[38]王焰山,张自文,黄晓萍,等.松针提取液对实验性高脂血症及脂质过氧化作用的影响[J].北京中医药大学学报,2001,24(2):35-36
[39]苏晓雨,王振宇.红松种子壳多酚物质的提取及抗氧化特性[J].农业工程学报,2009(s1):198-203
[40]李海涛,张良,盛玉青,等.松树皮原花青素的抗肿瘤作用研究[J].南京中医药大学学报,2007,23(1):43-45
[41]Qiang,Wang,Zhang,et al.Two new antitumor diterpenes from Pinus sylvestris[J].中国化学快报:英文版,2008,19(2):187-189
[42]刘光明,吕永俊,李好枝,等.云南松松塔中抗HIV活性成分的研究初报[J].大理大学学报,2009,8(2):69-71
[43]刘光明,吕永俊,周萍,等.松属植物的松塔、松子壳药用开发[J].大理大学学报,2007,6(12):77-80
[44]吕小满,胡艳芬,刘光明,等.松塔化学成分及生物活性的研究进展[J].医学综述,2010,16(7):1071-1073
[45]El-Ghorab A,El-Massry K,Shaaban H.Effect of Drying on the Chemical Composition of the Egyptian Cupressus macrocarpa(Hartw.ex Gordon)Essential Oils and their Biological Characteristics[J].Journal of Essential Oil Bearing Plants,2007,10(5):399-411
[46]肖靖萍,任宇红.松针抑菌作用的研究[J].食品科学,1994(2):52-54
[47]郭阿君,王志英,邹丽.樟子松挥发性有机物释放动态及其抑菌作用[J].东北林业大学学报,2014(4):115-118