摘要
目的:研究行微创保胆取石术后引起胆囊结石复发的危险因素以及针对方法。方法:收治胆囊结石患者100例,进行内镜保胆取石术,术后进行观察随访,对引起胆囊结石复发的危险因素展开分析。结果:复发率11%,单因素分析发现复发患者中合并息肉和结石数量≥3个、甘油三酯>1.7mmol/L、油腻的饮食习惯、胆囊收缩功能异常与结石复发的相关性较大,差异有统计学意义(P<0.05);多因素Logistic回归分析发现结石数量≥3个、油腻的饮食习惯、胆囊收缩功能异常是患者复发的3个独立危险因素,差异有统计学意义(P<0.05)。针对措施:调整饮食习惯,保持锻炼,个别结石较多的患者采取胆囊切除术。结论:结石数量≥3个、饮食习惯、胆囊收缩功能异常是结石复发的3个重要危险因素,术后进行干预,能够降低复发率。
Objective:To study the risk factors for recurrence of cholecystolithiasis after minimally invasive gallbladder preserving lithotomy and the corresponding methods.Methods:100 cases of cholecystolithiasis were treated by endoscopic cholecystolithotomy and postoperative follow-up.The risk factors for recurrence of gallstone were analyzed.Results:The recurrence rate was 11%.Univariate analysis found that:among relapsed patients,polyposis,number of stones≥3,triacylglycerols>1.7 mmol/L,greasy diet,gallbladder systolic dysfunction,and stone recurrence were more relevant,the difference was statistically significant(P<0.05).Multivariate Logistic regression analysis showed that the number of stones was more than 3,dietary habits and gallbladder contractility were the 3 independent risk factors for recurrence,and the difference was statistically significant(P<0.05).Measures:Adjust dietary habits,maintain exercise,cholecystectomy for patients with more individual stones.Conclusion:The number of stones is more than 3,eating habits and gallbladder contractility are the 3 important risk factors for stone recurrence.Postoperative intervention can reduce the recurrence rate.
引文
[1]刘永茂,李之令,刘江伟,等.微创保胆术后胆囊结石、息肉复发相关因素分析[J].山东医药,2017,23(57):94-96.
[2]葛海龙,万航.微创内镜保胆取石术术后胆囊结石复发的相关危险因素分析[J].滨州医学院学报,2016,2(39):149-150.
[3]马国杰,宋双庆,孔中宇.内镜微创保胆取石术后结石复发的危险因素分析[J].中国医药指南,2017,9(15):122-123.