银杏酸C15:1在水中溶解度的测定及关联
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摘要
采用荧光光度法,通过固-液平衡装置测定了从288.15 K到313.15 K温度下银杏酸C15:1在水中的溶解度,并分别应用Apelblat模型及理想溶液模型对试验数据进行了关联,总平均相对误差分别为4.50%和2.44%.结果表明:银杏酸C15:1在水中的溶解度随温度的升高而增大,溶解度的理想溶液模型和Apelblat模型在文中的研究温度和溶解度范围内是适用的,而Apelblat模型的模拟结果要优于理想溶液模型的模拟结果,其溶解度关联值与试验值比较吻合.通过van't Hoff方程计算出银杏酸C15:1在水中的溶解焓和溶解熵均为正值,表明银杏酸C15:1在水中的溶解过程为吸热过程.
The solubility of gingkgolic acid C15: 1 in water was measured with solid-liquid equilibrium apparatus by fluorometry at temperature range from 288. 15 to 313. 15 K. The experimental data were correlated with models based on the Apelblat equation and ideal solution equation. The total average relative errors are 4. 50% and 2. 44%,respectively. The results show that the solubility of ginkgolic acid C15: 1 is increased with the increasing of temperature. Ideal solution equation and Apelblat equation of solubility are applicable for the specified temperature and solubility in the research. The simulated result of Apelblat equation is superior to that of ideal solution equation,and the predictive values are consistent with the experimental results. The values of entropy and enthalpy change of gingkgolic acid C15: 1 in water are both positive according to van' t Hoff equtation,which indicates that the dissolve process of gingkgolic acid C15: 1 in water is an endothermic process.
The solubility of gingkgolic acid C15: 1 in water was measured with solid-liquid equilibrium apparatus by fluorometry at temperature range from 288. 15 to 313. 15 K. The experimental data were correlated with models based on the Apelblat equation and ideal solution equation. The total average relative errors are 4. 50% and 2. 44%,respectively. The results show that the solubility of ginkgolic acid C15: 1 is increased with the increasing of temperature. Ideal solution equation and Apelblat equation of solubility are applicable for the specified temperature and solubility in the research. The simulated result of Apelblat equation is superior to that of ideal solution equation,and the predictive values are consistent with the experimental results. The values of entropy and enthalpy change of gingkgolic acid C15: 1 in water are both positive according to van' t Hoff equtation,which indicates that the dissolve process of gingkgolic acid C15: 1 in water is an endothermic process.
引文
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[5]Hsieh C C,Hernndez-Ledesma B,de Lumen B O.Cell proliferation inhibitory and apoptosis-inducing properties of anacardic acid and lunasin in human breast cancer MDA-MB-231 cells[J].Food Chemistry,2011,125(2):630-636.
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[9]Liu J Q,Chen S Y,Ji B.Solubility and thermodynamic functions of isatin in pure solvents[J].Journal of Chemical&Engineering Data,2014,59:3407-3414.
[10]Zhang X,Gang Q,Rui W,et al.Correlation of solubility and calculation of thermodynamic properties of guanidine nitrate in different solvents[J].Fluid Phase Equilibria,2015,388:59-65.
[11]Tao M,Zhao W,Gong J,et al.Determination of the solubility,dissolution enthalpy,and entropy of pioglitazone hydrochloride(form ii)in different pure solvents[J].Industrial&Engineering Chemistry Research,2013,52(8):3036-3041.