分析阿司匹林肠溶片治疗神经内科疾病的临床体会
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摘要
目的分析阿司匹林肠溶片治疗神经内科疾病的临床体会。方法选取本院2017年10月至2018年10月收治的脑梗死患者75例作为样本,两组患者均给予降压、吸氧、低分子肝素钙进行常规治疗。对照组给予阿司匹林治疗,观察组A给予常规剂量阿司匹林肠溶片治疗,观察组B给予高剂量阿司匹林肠溶片治疗,观察三组患者的治疗效果、神经功能评分、不良反应发生率。结果观察组A有效率为76%、治疗后神经功能评分为(63.16±1.59)分、恶心发生率为4%、呕吐率为0、出血率为4%、过敏率为0。观察组B有效率为96%、治疗后神经功能评分为(62.28±2.00)分、恶心发生率为4%。对照组有效率为80%、治疗后神经功能评分(63.30±1.46)分、恶心发生率为12%、呕吐率为8%、出血率为4%、过敏率为4%。三组有效率对比,观察组B最高(P<0.05)。三组治疗前后的神经功能评分对比,差异无统计学意义(P>0.05)。三组不良反应对比,对照组最高(P<0.05),观察组B与观察组A对比,差异无统计学意义(P>0.05)。结论采用高剂量阿司匹林肠溶片治疗神经内科脑梗死,有效率较高,且不良反应发生率未见提升,应用效果显著。
Objective To analyze the clinical experience of aspirin enteric-coated tablets in the treatment of neurological diseases.Methods 75 patients with cerebral infarction admitted to our hospital from October 2017 to October 2018 were selected as samples,both groups were given antihypertensive,oxygen inhalation and low molecular weight heparin calcium for routine treatment.The control group was treated with aspirin,the observation group A was treated with conventional dose of aspirin enteric-coated tablets,and the observation group B was treated with high dose of aspirin enteric-coated tablets, the therapeutic effect,neurological function score and incidence of adverse reactions of the three groups were observed. Results The effective rate of observation group A was 76%,the neurological function score was(63.16±1.59), the nausea rate was 4%,the vomiting rate was 0, the bleeding rate was 4%, the allergy rate was 0.In the observation group B, the effective rate was 96%,the neurological function score was(62.28±2.00)and the incidence of nausea was 4%.In the control group,the effective rate was 80%,the neurological function score was(63.30±1.46),the incidence of nausea was 12%,the vomiting rate was 8%,the bleeding rate was 4%,and the allergy rate was 4%.The effective rate of the three groups was the highest in the observation group B(P<0.05).There was no significant difference in neurological function scores between the three groups before and after treatment(P>0.05).The adverse reactions of the three groups were the highest in the control group(P<0.05).There was no significant difference between the observation group B and the observation group A(P>0.05).Conclusin The high-dose aspirin enteric-coated tablets are effective in the treatment of cerebral infarction in the department of neurology,and the incidence of adverse reactions has not been increased, the application effect is remakable.
Objective To analyze the clinical experience of aspirin enteric-coated tablets in the treatment of neurological diseases.Methods 75 patients with cerebral infarction admitted to our hospital from October 2017 to October 2018 were selected as samples,both groups were given antihypertensive,oxygen inhalation and low molecular weight heparin calcium for routine treatment.The control group was treated with aspirin,the observation group A was treated with conventional dose of aspirin enteric-coated tablets,and the observation group B was treated with high dose of aspirin enteric-coated tablets, the therapeutic effect,neurological function score and incidence of adverse reactions of the three groups were observed. Results The effective rate of observation group A was 76%,the neurological function score was(63.16±1.59), the nausea rate was 4%,the vomiting rate was 0, the bleeding rate was 4%, the allergy rate was 0.In the observation group B, the effective rate was 96%,the neurological function score was(62.28±2.00)and the incidence of nausea was 4%.In the control group,the effective rate was 80%,the neurological function score was(63.30±1.46),the incidence of nausea was 12%,the vomiting rate was 8%,the bleeding rate was 4%,and the allergy rate was 4%.The effective rate of the three groups was the highest in the observation group B(P<0.05).There was no significant difference in neurological function scores between the three groups before and after treatment(P>0.05).The adverse reactions of the three groups were the highest in the control group(P<0.05).There was no significant difference between the observation group B and the observation group A(P>0.05).Conclusin The high-dose aspirin enteric-coated tablets are effective in the treatment of cerebral infarction in the department of neurology,and the incidence of adverse reactions has not been increased, the application effect is remakable.
引文
[1]李雁翔,常虹.阿司匹林联合氯吡格雷双联抗血小板治疗急性脑梗死的作用研究[J].中国处方药,2019,17(03):61-62.
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[4]马黎娟.缺血性卒中合并慢性胃炎患者经长期口服小剂量肠溶阿司匹林治疗的临床效果观察[J].世界最新医学信息文摘,2016,16(82):139-140.
[5]王根强.瑞舒伐他汀钙胶囊联合阿司匹林肠溶片和氯吡格雷片治疗老年急性脑梗死的临床研究[J].中国临床药理学杂志,2018,34(15):1755-1757,1761.
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[7]李琼.阿司匹林肠溶片治疗神经内科疾病应用体会[J].婚育与健康·实用诊疗,2014(10):42,59.
[8]左洪亮.阿司匹林肠溶片治疗缺血性脑血管疾病的临床效果观察[J].医学信息,2018(18):126-128.
[9]朱金虎.阿司匹林肠溶片在缺血性脑血管疾病临床治疗中的应用体会[J].中国药物与临床,2017,17(9):1354-1355.
[10]郑金妹.阿司匹林肠溶片治疗神经内科疾病应用体会[J].养生保健指南,2016(19):200-200.
[11]秦得营.阿司匹林肠溶片治疗神经内科疾病应用分析[J].北方药学,2017(2):72-73.
[12]杨福云.神经内科疾病应用阿司匹林肠溶片治疗的临床效果探析[J].医药前沿,2017,7(23):156-157.
[2]许磊,田少辉,孙强.阿司匹林对高血压基底节区脑出血术后再出血的影响及血小板治疗的疗效[J].中国实用神经疾病杂志,2016,19(18):107-109.
[3]常红,杨颖.进展性脑梗死患者经阿司匹林联合氯吡格雷双抗治疗的临床效果探讨[J].中国医药指南,2019,17(05):114-115.
[4]马黎娟.缺血性卒中合并慢性胃炎患者经长期口服小剂量肠溶阿司匹林治疗的临床效果观察[J].世界最新医学信息文摘,2016,16(82):139-140.
[5]王根强.瑞舒伐他汀钙胶囊联合阿司匹林肠溶片和氯吡格雷片治疗老年急性脑梗死的临床研究[J].中国临床药理学杂志,2018,34(15):1755-1757,1761.
[6]纪俐娜,姜山.阿司匹林肠溶片治疗神经内科疾病应用体会[J].世界最新医学信息文摘,2017,17(A4):92-92.
[7]李琼.阿司匹林肠溶片治疗神经内科疾病应用体会[J].婚育与健康·实用诊疗,2014(10):42,59.
[8]左洪亮.阿司匹林肠溶片治疗缺血性脑血管疾病的临床效果观察[J].医学信息,2018(18):126-128.
[9]朱金虎.阿司匹林肠溶片在缺血性脑血管疾病临床治疗中的应用体会[J].中国药物与临床,2017,17(9):1354-1355.
[10]郑金妹.阿司匹林肠溶片治疗神经内科疾病应用体会[J].养生保健指南,2016(19):200-200.
[11]秦得营.阿司匹林肠溶片治疗神经内科疾病应用分析[J].北方药学,2017(2):72-73.
[12]杨福云.神经内科疾病应用阿司匹林肠溶片治疗的临床效果探析[J].医药前沿,2017,7(23):156-157.
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