PET-CT误诊硬化性肺细胞瘤2例
摘要
<正>硬化性肺细胞瘤(PSH),也称肺硬化性血管瘤,为相对罕见的肺部良性肿瘤~[1]。近年来,越来越多关于PSH的正电子发射计算机断层显像-电子计算机X射线断层扫描技术(PET-CT)影像学表现为恶性肿瘤特性的报道,但常难以与恶性肿瘤鉴别而误诊,大部分经手术切除或活检而明确诊断。本文回顾性分析两例PET-CT的PSH影像及临床资料,旨在进一步提高对PSH的认识。1 临床资料病例1:女性,55岁,因胸闷气促、背部隐痛
引文
[1] LIEBOW A A,HUBBELL D S.Sclerosing hemangioma (histiocytoma,xanthoma)of the lung[J].Cancer,1956,9(1):53-75.
[2] DEVOUASSOUX SHISHEBORAN M,HAYASHI T,LINNOILA R I,et al.A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies:TTF-1 is expressed in both round and surface cells,suggesting an origin from primitive respiratory epithelium[J].Am J Surg Pathol,2000,24(7):906-916.
[3] 冯飞跃,程贵余,高树庚,等.肺硬化性血管瘤的诊断和手术治疗[J].中华医学杂志,2012,92(17):1190-1193.
[4] 张杰,邵晋晨,朱蕾.2015版WHO肺肿瘤分类解读[J].中华病理学杂志,2015,44(9):619-624.
[5] CHUNG M,LEE K,HAN J,et al.Pulmonary sclerosing hemangioma presenting as solitary pulmonary nodule:dynamic CT findings and histopathologic comparisons[J].Am J Roentgenol,2006,187(2):430-437.
[6] 刘加夫,侯立坤,武春燕.肺硬化性血管瘤120例临床病理分析[J].临床与实验病理学杂志,2015,31(2):174-177.
[7] XU H M,ZHANG G.A rare case of pulmonary sclerosing hemagioma with lymph node metastasis and review of the literature[J].Int J Clin Exp Pathol,2015,8(7):8619-8623.
[8] KIM M,JANG S,KIM Y,et al.Bone metastasis in pulmonary sclerosing hemangioma[J].Korean J Intern Med,2015,30(6):928-930.
[9] 董有文,徐文贵,朱磊.CT 与18F-FDG PET/CT 影像在硬化性肺泡细胞瘤诊断中的价值[J].中国实验诊断学,2016,20(6):903-906.
[10] DAI S,ZHANG X,QI F,et al.Expression of E-cadherin,beta-catenin and p120ctn in the pulmonary sclerosing hemangioma[J].Lung Cancer,2007,57(1):54-59.
[11] 王振光,程楠,石彬,等.11C-蛋氨酸和11C-胆碱正电子发射计算机体层成像-CT对大鼠C6胶质瘤和慢性炎症模型的鉴别价值[J].中华放射学杂志,2015,49(8):619-621.
[12] PICCHIO M,MESSA C,LANDONI C,et al.Value of [11C]choline-positron emission tomography for re-staging prostate cancer:a comparison with [18F]fluorodeoxyglucose-positron emission tomography[J].J Urol,2003,169(4):1337-1340.
[13] KHAN N,ORIUCHI N,ZHANG H,et al.A comparative study of 11C-choline PET and [18F]fluorodeoxyglucose PET in the evaluation of lung cancer[J].Nucl Med Commun,2003,24(4):359-366.
[14] TSUDUKI E,KAWANA A,TAKEDA Y,et al.The usefulness of 11C-Choline-positron emission tomography in the diagnosis of sclerosing hemangioma of the lung:a case report[J].Nihon Kokyuki Gakkai Zasshi,2002,40(5):402-407.
[2] DEVOUASSOUX SHISHEBORAN M,HAYASHI T,LINNOILA R I,et al.A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies:TTF-1 is expressed in both round and surface cells,suggesting an origin from primitive respiratory epithelium[J].Am J Surg Pathol,2000,24(7):906-916.
[3] 冯飞跃,程贵余,高树庚,等.肺硬化性血管瘤的诊断和手术治疗[J].中华医学杂志,2012,92(17):1190-1193.
[4] 张杰,邵晋晨,朱蕾.2015版WHO肺肿瘤分类解读[J].中华病理学杂志,2015,44(9):619-624.
[5] CHUNG M,LEE K,HAN J,et al.Pulmonary sclerosing hemangioma presenting as solitary pulmonary nodule:dynamic CT findings and histopathologic comparisons[J].Am J Roentgenol,2006,187(2):430-437.
[6] 刘加夫,侯立坤,武春燕.肺硬化性血管瘤120例临床病理分析[J].临床与实验病理学杂志,2015,31(2):174-177.
[7] XU H M,ZHANG G.A rare case of pulmonary sclerosing hemagioma with lymph node metastasis and review of the literature[J].Int J Clin Exp Pathol,2015,8(7):8619-8623.
[8] KIM M,JANG S,KIM Y,et al.Bone metastasis in pulmonary sclerosing hemangioma[J].Korean J Intern Med,2015,30(6):928-930.
[9] 董有文,徐文贵,朱磊.CT 与18F-FDG PET/CT 影像在硬化性肺泡细胞瘤诊断中的价值[J].中国实验诊断学,2016,20(6):903-906.
[10] DAI S,ZHANG X,QI F,et al.Expression of E-cadherin,beta-catenin and p120ctn in the pulmonary sclerosing hemangioma[J].Lung Cancer,2007,57(1):54-59.
[11] 王振光,程楠,石彬,等.11C-蛋氨酸和11C-胆碱正电子发射计算机体层成像-CT对大鼠C6胶质瘤和慢性炎症模型的鉴别价值[J].中华放射学杂志,2015,49(8):619-621.
[12] PICCHIO M,MESSA C,LANDONI C,et al.Value of [11C]choline-positron emission tomography for re-staging prostate cancer:a comparison with [18F]fluorodeoxyglucose-positron emission tomography[J].J Urol,2003,169(4):1337-1340.
[13] KHAN N,ORIUCHI N,ZHANG H,et al.A comparative study of 11C-choline PET and [18F]fluorodeoxyglucose PET in the evaluation of lung cancer[J].Nucl Med Commun,2003,24(4):359-366.
[14] TSUDUKI E,KAWANA A,TAKEDA Y,et al.The usefulness of 11C-Choline-positron emission tomography in the diagnosis of sclerosing hemangioma of the lung:a case report[J].Nihon Kokyuki Gakkai Zasshi,2002,40(5):402-407.