贾英杰教授运用调肝法治疗肿瘤相关性失眠经验
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摘要
肿瘤相关性失眠是肿瘤患者常见伴随症状,因不及肿瘤危害性强,故临证时易于忽视,严重影响了患者生活质量且不利于疾病向愈。治疗时西医常以失眠论治,忽视其与肿瘤疾病的相关性。本病属中医"不寐"范畴,主要病位在心,治疗上强调辨证论治。贾英杰教授通过30余载临证经验总结,认为肿瘤患者不寐多归于情志因素,主要责之于肝,且与其他脏腑有密切联系,从肝论治多获良效。文章将围绕"疏利肝气以畅调达""调补肝虚以合肝用""清肝泻火以降肝气""顺应肝气四时变化"来论述调肝法在治疗肿瘤相关性失眠的临证经验与思路。
Cancer-related insomnia is a common symptom of cancer patients,because it is not as harmful as the cancer,so it is easy to ignore the clinical symptoms. However,this disease seriously affecting the quality of life of patients and not conducive to the recovery.Western medicine often treats it as insomnia,but its correlation with cancer diseases is ignored. This disease belongs to the category of"insomnia" of traditional Chinese medicine. It location in the heart,emphasizes the syndrome differentiation and treatment,pays attention to a variety of factors under the influence of individual treatment. By summarizing 30 years of clinical experience,professor JIA Yingjie concluded that cancer-related insomnia more attributed to emotional factors,the main responsibility for it dues to the liver,which is also closely related to other zang fu. Treatment from liver is often effective. This paper revolve around "dredge the qi of liver to unobstructed","repair liver deficiency to enhance its function", "clearing heat and fire to conditioning the qi of liver", "adaptation the qi of liver with four seasons change" to discuss the experience in the treatment of cancer-related insomnia by liver regulating method.
Cancer-related insomnia is a common symptom of cancer patients,because it is not as harmful as the cancer,so it is easy to ignore the clinical symptoms. However,this disease seriously affecting the quality of life of patients and not conducive to the recovery.Western medicine often treats it as insomnia,but its correlation with cancer diseases is ignored. This disease belongs to the category of"insomnia" of traditional Chinese medicine. It location in the heart,emphasizes the syndrome differentiation and treatment,pays attention to a variety of factors under the influence of individual treatment. By summarizing 30 years of clinical experience,professor JIA Yingjie concluded that cancer-related insomnia more attributed to emotional factors,the main responsibility for it dues to the liver,which is also closely related to other zang fu. Treatment from liver is often effective. This paper revolve around "dredge the qi of liver to unobstructed","repair liver deficiency to enhance its function", "clearing heat and fire to conditioning the qi of liver", "adaptation the qi of liver with four seasons change" to discuss the experience in the treatment of cancer-related insomnia by liver regulating method.
引文
[1] Induru RR,Walsh D. Cancer-Related Insomnia[J]. American Journal of Hospice&Palliative Medicine,2014,31(7):777-785.
[2] Pachman DR,Barton DL,Swetz KM,et al. Troublesome symptoms in cancer survivors:fatigue,insomnia,neuropathy,and pain[J]. J Clin Oncol,2012,30(30):3687-3696.
[3]马捷,李峰,宋月晗,等.从肝论治失眠的文献研究[J].中华中医药杂志,2012,27(4):1076-1080.
[4]杨阳,马淑然,王庆国,等.论“四时之肝”对季节性情感障碍发病的“生物钟”作用机制[J].中华中医药杂志,2011,26(11):2529-2532.
[5]李小江,贾英杰,张文治,等.姜黄素对A549细胞亚群SP及NON-SP细胞凋亡的诱导作用[J].中草药,2013,44(18):2581-2584.
[6]朱亚平,卜淑蕊.姜黄素抗肿瘤作用机制研究进展[J].上海中医药杂志,2018,52(3):91-93.
[7]左琳,满其倩,容蓉,等.白花蛇舌草抗肿瘤有效成分及其机制最新研究进展[J].辽宁中医杂志,2015,42(10):1963-1964.
[8]凌汶静,郝迎旭.常用抗肿瘤中药的临床应用与规律探讨[D].北京:北京中医药大学,2015.
[2] Pachman DR,Barton DL,Swetz KM,et al. Troublesome symptoms in cancer survivors:fatigue,insomnia,neuropathy,and pain[J]. J Clin Oncol,2012,30(30):3687-3696.
[3]马捷,李峰,宋月晗,等.从肝论治失眠的文献研究[J].中华中医药杂志,2012,27(4):1076-1080.
[4]杨阳,马淑然,王庆国,等.论“四时之肝”对季节性情感障碍发病的“生物钟”作用机制[J].中华中医药杂志,2011,26(11):2529-2532.
[5]李小江,贾英杰,张文治,等.姜黄素对A549细胞亚群SP及NON-SP细胞凋亡的诱导作用[J].中草药,2013,44(18):2581-2584.
[6]朱亚平,卜淑蕊.姜黄素抗肿瘤作用机制研究进展[J].上海中医药杂志,2018,52(3):91-93.
[7]左琳,满其倩,容蓉,等.白花蛇舌草抗肿瘤有效成分及其机制最新研究进展[J].辽宁中医杂志,2015,42(10):1963-1964.
[8]凌汶静,郝迎旭.常用抗肿瘤中药的临床应用与规律探讨[D].北京:北京中医药大学,2015.