胸腔积液中非肿瘤细胞的细胞学检查研究进展
摘要
细胞学检查在鉴别胸腔积液的良恶性方面具有很重要的临床价值。非肿瘤性细胞是胸腔积液中的重要成分,其中包括间皮细胞、淋巴细胞、巨噬细胞、中性粒细胞等。同时非肿瘤细胞对积液良恶性的诊断具有特殊作用,而胸腔积液中的非肿瘤细胞的检测方法、存在量及其应用价值等对正确诊断具有重要的意义。
引文
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[21]宋雪娜,杨华,刘君.Th1/Th2免疫应答平衡在结核性和恶性肿瘤性胸腔积液中的意义[J].中国肿瘤临床与康复,2014,21(9):1052-1054.
[22]罗玲娟,张立平,谢新梅,等.CD4+CD25+调节性T细胞及其相关因子在恶性肿瘤患者胸腔积液及外周血中的表达[J].川北医学院学报,2016,31(3):413-415.
[23]罗维贵,唐任光.胸腔积液间皮细胞和巨噬细胞对良、恶性胸腔积液的鉴别诊断价值[J].右江民族医学院学报,1999,21(6):898-900.
[24]Risberg B,Davidson B,Nielsen S,et al.Detection of monocyte/macrophage cell populations in effusions:a comparative study using flow cytometric immunophenotyping and immunocytochemistry[J].Diagn Cytopathol,2001,25(4):214-219.
[25]董关云,吴茅,郑素洁,等.106例浆膜腔积液嗜酸性粒细胞增多的临床分析[J].中国卫生检验杂志,2014,24(3):411-412,415.
[26]韩冬,齐翠荣,张恒嘉.98例肺癌患者伴嗜酸细胞增多性胸腔积液探讨[J].中国体视学与图像分析,2014,19(4):398-402.
[27]翟惠芬,徐波,王维,等.渗出性胸腔积液69例临床分析[J].北京医学,2016,38(7):703-705.
[28]Li L,Yang L,Wang L,et al.Impaired T cell function in malignant pleural effusion is caused by TGF-βderived predominantly from macrophages[J].Int J Cancer,2016,139(10):2261-2269.
[29]Liu C,Workman CJ,Vignali DA.Targeting regulatory T cells in tumors[J].FEBS J,2016,283(14):2731-2748.
[2]张勇,伍淑娴,余秀文,等.全自动五分类血液分析仪在胸腹水检测中的应用[J].国际检验医学杂志,2010,31(10):1175-1176.
[3]陈暖,彭学宏,李微.胸水间皮细胞计数对胸腔积液56例诊断分析[J].中国误诊学杂志,2008,8(21):5216-5217.
[4]张伟民,吴茅,乐美萍,等.计算机图像分析软件在浆膜腔积液细胞测量中的应用[J].中华检验医学杂志,2006,29(6):502-504.
[5]Kaczmarek M,Nowicka A,Kozowska M,et al.Evaluation of the phenotype pattern of macrophages isolated from malignant and non-malignant pleural effusions[J].Tumour Biol,2011,32(6):1123-1132.
[6]朱杰,王善菊,聂大平,等.DNA含量分析和非白细胞细胞群CD44分子的检测在胸腔积液诊断和鉴别诊断中的价值[J].大连医科大学学报,2009,31(2):200-203.
[7]郑玉兰,吴金如,李向阳,等.流式细胞仪检测恶性胸腔积液中T淋巴细胞亚群变化[J].现代预防医学,2010,37(14):2720-2721.
[8]黄其文,姜汉国.胸腔积液细胞块切片免疫组化染色技术鉴别诊断肺腺癌的临床研究[J].临床肺科杂志,2017,22(2):227-229.
[9]王微.间皮细胞计数在鉴别结核性、恶性胸水中的价值[J].医药前沿,2013,(28):47-48.
[10]巫天贤,金雪文.腺甘脱氨酶和间皮细胞计数在鉴别结核性与恶性胸水中的价值[J].温州医学院学报,2012,42(6):580-582.
[11]殷宗宝,谭元,陈彦凡,等.癌胚抗原和腺苷脱氨酶水平及间皮细胞计数对恶性与结核性胸腔积液的鉴别诊断价值[J].中国全科医学,2009,12(6):450-452.
[12]蓝永洪,牛海艳,饶朗毓,等.胸水中腺癌细胞和反应性间皮细胞的计算机判别[J].南京医科大学学报(自然科学版),2013,33(8):1152-1154.
[13]Moghaddam NA,Rahmani A,Taheri D,et al.Proliferative index using Ki-67 index in reactive mesothelial versus metastatic adenocarcinoma cells in serous fluid[J].Adv Biomed Res,2012,1:29.
[14]Akturk UA,Ernam D,Akbay MO,et al.Role of the Neutrophil-Lymphocyte Ratio in the Differential Diagnosis of Exudative Pleural Effusion[J].Clinics(Sao Paulo),2016,71(10):611-616.
[15]陈永浩,陈志成.结核性和癌性胸腔积液中淋巴细胞亚群比例变化的研究[J].国际医药卫生导报,2006,12(13):13-15.
[16]Verma A,Dagaonkar RS,Marshall D,et al.Differentiating Malignant from Tubercular Pleural Effusion by Cancer Ratio Plus(Cancer Ratio:Pleural Lymphocyte Count)[J].Can Respir J,2016,2016:7348239.
[17]Gjomarkaj M,Pace E,Melis M,et al.Mononuclear cells in exudative malignant pleural effusions.Characterization of pleural phagocytic cells[J].Chest,1994,106(4):1042-1049.
[18]Choi H,Chon HR,Kim K,et al.Clinical and Laboratory Differences between Lymphocyte-and Neutrophil-Predominant Pleural Tuberculosis[J].PLo S One,2016,11(10):e0165428.
[19]Goseva Z,Kaeva BJ,Gjorcev A,et al.Analysis of Lymphocyte Immunological Reactivity in Patients with Pleural Effusions of Different Aetiology[J].Open Access Maced J Med Sci,2016,4(1):50-53.
[20]戈启萍,贺正一,高微微,等.流式细胞术检测特异性刺激后淋巴细胞亚群变化对结核性胸腔积液的诊断价值[J].中华结核和呼吸杂志,2013,36(6):406-410.
[21]宋雪娜,杨华,刘君.Th1/Th2免疫应答平衡在结核性和恶性肿瘤性胸腔积液中的意义[J].中国肿瘤临床与康复,2014,21(9):1052-1054.
[22]罗玲娟,张立平,谢新梅,等.CD4+CD25+调节性T细胞及其相关因子在恶性肿瘤患者胸腔积液及外周血中的表达[J].川北医学院学报,2016,31(3):413-415.
[23]罗维贵,唐任光.胸腔积液间皮细胞和巨噬细胞对良、恶性胸腔积液的鉴别诊断价值[J].右江民族医学院学报,1999,21(6):898-900.
[24]Risberg B,Davidson B,Nielsen S,et al.Detection of monocyte/macrophage cell populations in effusions:a comparative study using flow cytometric immunophenotyping and immunocytochemistry[J].Diagn Cytopathol,2001,25(4):214-219.
[25]董关云,吴茅,郑素洁,等.106例浆膜腔积液嗜酸性粒细胞增多的临床分析[J].中国卫生检验杂志,2014,24(3):411-412,415.
[26]韩冬,齐翠荣,张恒嘉.98例肺癌患者伴嗜酸细胞增多性胸腔积液探讨[J].中国体视学与图像分析,2014,19(4):398-402.
[27]翟惠芬,徐波,王维,等.渗出性胸腔积液69例临床分析[J].北京医学,2016,38(7):703-705.
[28]Li L,Yang L,Wang L,et al.Impaired T cell function in malignant pleural effusion is caused by TGF-βderived predominantly from macrophages[J].Int J Cancer,2016,139(10):2261-2269.
[29]Liu C,Workman CJ,Vignali DA.Targeting regulatory T cells in tumors[J].FEBS J,2016,283(14):2731-2748.