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血栓弹力图应用于肿瘤患者高凝状态诊断的临床价值研究
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  • 英文篇名:Study on the clinical value of the application of thrombelastogram in the diagnosis of high coagulation state in patients with cancer
  • 作者:黄辉 ; 岳银萍 ; 王旭 ; 张兰胜
  • 英文作者:Huang Hui;Yue Yinping;Wang Xu;Zhang Lansheng;The Second Affiliated Hospital of Xuzhou Medical College;
  • 关键词:血栓弹力图 ; 肿瘤 ; 高凝状态
  • 英文关键词:Thrombelastogram;;Tumor;;High coagulation state
  • 中文刊名:XCYS
  • 英文刊名:Chinese Community Doctors
  • 机构:徐州医学院第二附属医院;
  • 出版日期:2016-06-21 09:03
  • 出版单位:中国社区医师
  • 年:2016
  • 期:v.32
  • 语种:中文;
  • 页:XCYS201617082
  • 页数:2
  • CN:17
  • ISSN:22-1405/R
  • 分类号:132+134
摘要
目的:探讨血栓弹力图应用于肿瘤患者高凝状态诊断的临床价值。方法:收治肿瘤患者60例作为观察组,随机选取60例体检人群作为对照组,分析两组血栓弹力图、血小板计数、血凝试验参数、D-D二聚体及超声多普勒等检测数据。结果:观察组的反应时间明显长于对照组;D-二聚体、纤维蛋白原、最大幅度、纤维蛋白原降解产物及血小板数量等指标明显低于对照组(P<0.05)。结论:运用血栓弹力图、血小板计数、血凝试验参数、D-D二聚体及超声多普勒等诊断技术对肿瘤患者的凝血状态进行评估,可对血栓的危险性进行预测。
        Objective:To investigate the clinical value of the application of thrombelastogram in the diagnosis of tumor patients with high coagulation state.Methods:60 patients with cancer were selected as the observation group,while 60 cases taken physical examination were selected as the control group.The thrombelastogram,platelet count,blood coagulation parameters,D-D dimer and doppler ultrasound detection data were analyzed of the two groups.Results:The reaction time of the observation group was significantly higher than that of the control group.The D-dimer,fibrinogen,maximum amplitude,fibrinogen degradation products and platelet count were significantly lower than the control group(P<0.05).Conclusion:We predict the risk of thrombosis by assess the thrombelastogram,platelet count,blood coagulation parameters,D-D dimer and doppler ultrasound diagnostic techniques for tumor coagulation state.
引文
[1]Alcalay A,Wun T,Khatri V,et al.Venous thromboembolism in patients with colorectal cancer:incidence and effect on survival[J].JClin Oncol,2006,24(7):1112-1118.
    [2]王莉,刘义,高芸菲,等.预防恶性肿瘤患者静脉血栓栓塞症的临床分析[J].实用临床医药杂志,2013,(7):118-120.
    [3]Christensen TD,Vad H,Pedersen S,et al.Venous thromboembolism in patients undergoing operations for lung cancer:a systematic review[J].Ann Thorac Surg,2014,97(2):394-400.
    [4]蔡毅,崔华,范利.血栓弹力图研究进展概况[J].中华老年心脑血管病杂志,2014,(11):1217-1218.

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