液相色谱质谱联用仪对白酒中甜蜜素测定的影响
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摘要
甜蜜素属于甜味剂的一种,国家标准中规定白酒中不得检出甜蜜素,长时间饮用含有甜蜜素的白酒会给人体带来不利影响。采用国家标准规定的液相色谱-串联质谱法检测酒类甜蜜素的过程中发现,不同厂家的液质联用仪优化出的正离子模式下所监测的202> 122(ESI正离子模式)离子对不同,且差别大。从液相色谱质谱联用仪结构的角度分析原因,可为标准的修订提供参考。
Sodium cyclamate is a kind of sweetening agent. According to national standards the cyclamate in liquor shall not be detected. Consumers for a long time to drink alcohol containing sodium cyclamate will bring harm and adverse effects to the human body. The national standards of sodium cyclamate detection in wine by HPLC-MS/MS found that different manufacturer of fluid mass monitoring by the ms method to optimize the positive ion mode 202> 122(ESI Positive Ion Mode) ion pair is different. A solution may be provided for the revision of the standard by analyzing the cause from the perspective of the structure of the liquid chromatography mass spectrometry.
Sodium cyclamate is a kind of sweetening agent. According to national standards the cyclamate in liquor shall not be detected. Consumers for a long time to drink alcohol containing sodium cyclamate will bring harm and adverse effects to the human body. The national standards of sodium cyclamate detection in wine by HPLC-MS/MS found that different manufacturer of fluid mass monitoring by the ms method to optimize the positive ion mode 202> 122(ESI Positive Ion Mode) ion pair is different. A solution may be provided for the revision of the standard by analyzing the cause from the perspective of the structure of the liquid chromatography mass spectrometry.
引文
[1]王凯,邱宇,王亮亮,等.液相色谱-串联质谱法测定白酒中甜蜜素的不确定度评价[J].食品安全质量检测学报,2018,9(6):1449-1454.
[2]孙贺,赵颖,陈路露.采用超高效液相色谱-串联质谱法测定白酒中甜蜜素含量的方法改进[J].酿酒,2018,45(2):93-95.
[3]盛静,向春燕.液质联用法测定白酒中甜蜜素含量的不确定度评定[J].现代食品,2018(2):90-92,95.
[4]王烁,柯润辉,安红梅,等.气相色谱-火焰热离子检测器法测定白酒中甜蜜素的研究[J].酿酒科技,2018(2):125-129.
[5]邵彪,周小兰,王琳琳,等.甜蜜素的电喷雾串联质谱行为及其在酒类分析检测中的应用研究[J].中国食品催化剂,2018(6):166-172.
[2]孙贺,赵颖,陈路露.采用超高效液相色谱-串联质谱法测定白酒中甜蜜素含量的方法改进[J].酿酒,2018,45(2):93-95.
[3]盛静,向春燕.液质联用法测定白酒中甜蜜素含量的不确定度评定[J].现代食品,2018(2):90-92,95.
[4]王烁,柯润辉,安红梅,等.气相色谱-火焰热离子检测器法测定白酒中甜蜜素的研究[J].酿酒科技,2018(2):125-129.
[5]邵彪,周小兰,王琳琳,等.甜蜜素的电喷雾串联质谱行为及其在酒类分析检测中的应用研究[J].中国食品催化剂,2018(6):166-172.