记忆神经环路的研究进展
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摘要
记忆是脑的高级神经功能,根据记忆持续的时间可分为感觉记忆、短时记忆和长时记忆。记忆是脑内神经核团及其互相之间联系形成的神经环路编码,不同的神经环路可能参与一种或多种记忆类型。高度特异性的神经环路和细胞功能干预技术(如光遗传学和化学遗传学技术等)的发展极大地促进了人们对记忆神经环路机制的认识。现就几种记忆的相关脑区及神经环路做一综述。
Memory is the advanced neurological function of the brain.According to the duration of memory,it can be divided into sensory memory,short-term memory and long-term memory.Memory is encoded by the neural circuits formed by the nucleis in the brain and their connections with each other.Different neural circuits may participate in one or more memory types.The development of highly specific neural circuits and cell function intervention techniques(such as optogenetics and chemical genetics techniques)has greatly promoted people's recognition for the mechanism of memory neural circuits.This article reviews several memory related brain regions and neural circuits.
Memory is the advanced neurological function of the brain.According to the duration of memory,it can be divided into sensory memory,short-term memory and long-term memory.Memory is encoded by the neural circuits formed by the nucleis in the brain and their connections with each other.Different neural circuits may participate in one or more memory types.The development of highly specific neural circuits and cell function intervention techniques(such as optogenetics and chemical genetics techniques)has greatly promoted people's recognition for the mechanism of memory neural circuits.This article reviews several memory related brain regions and neural circuits.
引文
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[30]JACKSON R L,HOFFMAN P,POBRIC G,et al.The semantic network at work and rest:differential connectivity of anterior temporal lobe subregions[J].J Neurosci,2016,36(5):1490-1501.
[31]GROSSMAN M,SMITH E E,KOENIG P,et al.The neural basis for categorization in semantic memory[J].NeuroImage,2002,17(3):1549-1561.
[32]HART J,MAGUIRE M J,MOTES M,et al.Semantic memory retrieval circuit:Role of pre-SMA,caudate,and thalamus[J].Brain Lang,2013,126(1):89-98.
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[35]GLYN V,LIM V K,HAMM J P,et al.Behavioural and electrophysiological effects related to semantic violations during braille reading[J].Neuropsychologia,2015(77):298-312.
[36]KITAMURA T,INOKUCHI K.Role of adult neurogenesis in hippocampal-cortical memory consolidation[J].Mol Brain,2014(7):13.
[37]LIU Y,LIN W,LIU C,et al.Memory consolidation reconfigures neural pathways involved in the suppression of emotional memories[J].Nat Commun,2016(7):13375.
[38]YE L,ALLEN W E,THOMPSON K R,et al.Wiring and molecular features of prefrontal ensembles representing distinct experiences[J].Cell,2016,165(7):1776-1788.
[39]TONEGAWA S,LIU X,RAMIREZ S,et al.Memory engram cells have come of age[J].Neuron,2015,87(5):918-931.
[40]DEISSEROTH K.Optogenetics:10years of microbial opsins in neuroscience[J].Nat Neurosci,2015,18(9):1213-1225.
[41]ZIV Y,BURNS L D,COCKER E D,et al.Long-term dynamics of CA1hippocampal place codes[J].Nat Neurosci,2013,16(3):264-266.
[42]TONEGAWA S,PIGNATELLI M,ROY D S,et al.Memory engram storage and retrieval[J].Curr Opin Neurobiol,2015(35):101-109.
[43]ROY D S,ARONS A,MITCHELL T I,et al.Memory retrieval by activating engram cells in mouse models of early Alzheimer′s disease[J].Nature,2016,531(7595):508-512.
[44]KITAMURA K,OGAWA S K,ROY D S,et al.Engrams and circuits crucial for systems consolidation of a memory[J].Science,2017(356):73-78.
[2]MATTHEWS B R.Memory dysfunction[J].Continuum,2015,21(3):613-626.
[3]SQUIRE L R,GENZEL L,WIXTED J T,et al.Memory consolidation[J].Cold Spring Harb Perspect Biol,2015,7(8):a021766.
[4]PENFIED W,KRISTIANSEN K.Seizure onset and the localization of epileptic discharge[J].Trans Am Neurol Assoc,1948(73):73-80.
[5]SCOVILLE W B,MILNER B.Loss of recent memory after bilateral hippocampal lesions[J]J Neurol Neurosurg Psychiat,1957(20):11-21.
[6]BASU J,SIEGELBAUM S A.The corticohippocampal circuit,synaptic plasticity,and memory[J].Cold Spring Harb Perspect Biol,2015,7(11):a021733.
[7]ZERR P,GAYET S,MULDER K,et al.Remapping highcapacity,pre-attentive,fragile sensory memory[J].Sci Rep,2017,7(1):15940.
[8]GOLD J M,BARCH D M,FEUERSTAHLER L M,et al.Working memory impairment across psychotic disorders[J].Schizophr Bull,2018,31(1):109-112.
[9]BEZU M,MALIKOVIC J,KRISTOFOVA M,et al.Spatial working memory in male rats:pre-experience and task dependent roles of dopamine D1-and D2-like receptors[J].Front Behav Neurosci,2017(11):196.
[10]VON BOHLEN O,DRAGUHN A,STORM-MATHIS-EN J.Recent advances in hippocampal structure and function[J].Cell Tissue Res,2018,373(3):521-523.
[11]OH S W,HARRIS J A,NG L,et al.A mesoscale connectome of the mouse brain[J].Nature,2014,508(7495):207-214.
[12]SHALINI S M,CHEW W S,RAJKUMAR R,et al.Role of constitutive calcium-independent phospholipase A2beta in hippocampo-prefrontal cortical long term potentiation and spatial working memory[J].Neurochem Int,2014(78):96-104.
[13]SPELLMAN T,RIGOTTI M,AHMARI S E,et al.Hippocampal-prefrontal input supports spatial encoding in working memory[J].Nature,2015,522(7556):309-314.
[14]KUMAR S,ZOMORRODI R,GHAZALA Z,et al.Extent of dorsolateral prefrontal cortex plasticity and its association with working memory in patients with alzheimer disease[J].JAMA Psychiatry,2017,74(12):1266-1274.
[15]FUNAHASHI S.Thalamic mediodorsal nucleus and its participation in spatial working memory processes:comparison with the prefrontal cortex[J].Front Syst Neurosci,2013(7):1-13.
[16]PER?KYL?J,SUN L,LEHTIM?KI K,et al.Causal evidence from humans for the role of mediodorsal nucleus of the thalamus in working memory[J].J Cogn Neurosci,2017,29(12):1-13.
[17]BOLKAN S S,STUJENSKE J M,PARNAUDEAU S,et al.Thalamic projections sustain prefrontal activity during working memory maintenance[J].Nat Neurosci,2017,20(7):987-996.
[18]ALLEN T A,FORTIN N J.The evolution of episodic memory[J].Proc Natl Acad Sci U S A,2013,110Suppl2:10379-10386.
[19]LECH R K,SUCHAN B.The medial temporal lobe:memory and beyond[J].Behav Brain Res,2013(254):45-49.
[20]CHEN J,SHU H,WANG Z,et al.Protective effect of APOE epsilon 2on intrinsic functional connectivity of the entorhinal cortex is associated with better episodic memory in elderly individuals with risk factors for Alzheimer′s disease[J].Oncotarget,2016,7(37):58798-58801.
[21]WITTER M P,DOAN T P,JACOBSEN B,et al.Architecture of the entorhinal cortex a review of entorhinal anatomy in rodents with some comparative notes[J].Front Syst Neurosci,2017(11):46.
[22]DING S L.Comparative anatomy of the prosubiculum,subiculum,presubiculum,postsubiculum,and parasubiculum in human,monkey,and rodent[J].J Comp Neurol,2013,521(18):4145-4162.
[23]ROY D S,KITAMURA T,OKUYAMA T,et al.Distinct neural circuits for the formation and retrieval of episodic memories[J].Cell,2017,170(5):1000-1012.
[24]EICHENBAUM H.Prefrontal-hippocampal interactions in episodic memory[J].Nat Rev Neurosci,2017,18(9):547-558.
[25]BARKER G R,BANKS P J,SCOTT H,et al.Separate elements of episodic memory subserved by distinct hippocampal-prefrontal connections[J].Nat Neurosci,2017,20(2):242-250.
[26]ELWARD R L,VARGHA-KHADEM F.Semantic memory in developmental amnesia[J].Neurosci Lett,2018(680):23-30.
[27]WESTERLUND M,PYLKKANEN L.The role of the left anterior temporal lobe in semantic composition vs.semantic memory[J].Neuropsychologia,2014(57):59-70.
[28]GERANMAYEH F,LEECH R,WISE R J.Semantic retrieval during overt picture description:Left anterior temporal or the parietal lobe?[J].Neuropsychologia,2015(76):125-135.
[29]SHIMOTAKE A,MATSUMOTO R,UENO T,et al.Direct exploration of the role of the ventral anterior temporal lobe in semantic memory:cortical stimulation and local field potential evidence from subdural grid electrodes[J].Cereb Cortex,2015,25(10):3802-3817.
[30]JACKSON R L,HOFFMAN P,POBRIC G,et al.The semantic network at work and rest:differential connectivity of anterior temporal lobe subregions[J].J Neurosci,2016,36(5):1490-1501.
[31]GROSSMAN M,SMITH E E,KOENIG P,et al.The neural basis for categorization in semantic memory[J].NeuroImage,2002,17(3):1549-1561.
[32]HART J,MAGUIRE M J,MOTES M,et al.Semantic memory retrieval circuit:Role of pre-SMA,caudate,and thalamus[J].Brain Lang,2013,126(1):89-98.
[33]JEFFERIES E.The neural basis of semantic cognition:Converging evidence from neuropsychology,neuroimaging and TMS[J].Cortex,2013,49(3):611-625.
[34]NOONAN K A,JEFFERIES E,VISSER M,et al.Going beyond inferior prefrontal involvement in semantic control:evidence for the additional contribution of dorsal angular gyrus and posterior middle temporal cortex[J].JCogn Neurosci,2013,25(11):1824-1850.
[35]GLYN V,LIM V K,HAMM J P,et al.Behavioural and electrophysiological effects related to semantic violations during braille reading[J].Neuropsychologia,2015(77):298-312.
[36]KITAMURA T,INOKUCHI K.Role of adult neurogenesis in hippocampal-cortical memory consolidation[J].Mol Brain,2014(7):13.
[37]LIU Y,LIN W,LIU C,et al.Memory consolidation reconfigures neural pathways involved in the suppression of emotional memories[J].Nat Commun,2016(7):13375.
[38]YE L,ALLEN W E,THOMPSON K R,et al.Wiring and molecular features of prefrontal ensembles representing distinct experiences[J].Cell,2016,165(7):1776-1788.
[39]TONEGAWA S,LIU X,RAMIREZ S,et al.Memory engram cells have come of age[J].Neuron,2015,87(5):918-931.
[40]DEISSEROTH K.Optogenetics:10years of microbial opsins in neuroscience[J].Nat Neurosci,2015,18(9):1213-1225.
[41]ZIV Y,BURNS L D,COCKER E D,et al.Long-term dynamics of CA1hippocampal place codes[J].Nat Neurosci,2013,16(3):264-266.
[42]TONEGAWA S,PIGNATELLI M,ROY D S,et al.Memory engram storage and retrieval[J].Curr Opin Neurobiol,2015(35):101-109.
[43]ROY D S,ARONS A,MITCHELL T I,et al.Memory retrieval by activating engram cells in mouse models of early Alzheimer′s disease[J].Nature,2016,531(7595):508-512.
[44]KITAMURA K,OGAWA S K,ROY D S,et al.Engrams and circuits crucial for systems consolidation of a memory[J].Science,2017(356):73-78.