Lipid storage regulator CdsA is essential for Drosophila metamorphosis
|
摘要
<正>Steroid hormones are one of the major bioactive lipid species that regulate a large number of physiological processes including developmental transitions, growth, metabolism, inflammation, immune response and reproduction in animals. In insects, steroid hormones ecdysone and 20-hydroxyecdysone (20E) trigger the major
引文
Britton,J.S.,Lockwood,W.K.,Li,L.,Cohen,S.M.,Edgar,B.A.,2002.Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions.Dev.Cell 2,239e249.
Colombani,J.,Bianchini,L.,Layalle,S.,Pondeville,E.,Dauphin-Villemant,C.,Antoniewski,C.,Carre,C.,Noselli,S.,Leopold,P.,2005.Antagonistic actions of ecdysone and insulins determine final size in Drosophila.Science 310,667e670.
Gilbert,L.I.,Rybczynski,R.,Warren,J.T.,2002.Control and biochemical nature of the ecdysteroidogenic pathway.Annu.Rev.Entomol.47,883e916.
Gronke,S.,Mildner,A.,Fellert,S.,Tennagels,N.,Petry,S.,Muller,G.,Jackle,H.,Kuhnlein,R.P.,2005.Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila.Cell Metabol.1,323e330.
Huang,X.,Suyama,K.,Buchanan,J.,Zhu,A.J.,Scott,M.P.,2005.A Drosophila model of the Niemann-Pick type C lysosome storage disease:dnpc1a is required for molting and sterol homeostasis.Development 132,5115e5124.
Huang,X.,Warren,J.T.,Buchanan,J.,Gilbert,L.I.,Scott,M.P.,2007.Drosophila Niemann-Pick type C-2 genes control sterol homeostasis and steroid biosynthesis:a model of human neurodegenerative disease.Development 134,3733e3742.
Huang,X.,Warren,J.T.,Gilbert,L.I.,2008.New players in the regulation of ecdysone biosynthesis.J.Genet.Genomics 35,1e10.
Laurinyecz,B.,Peter,M.,Vedelek,V.,Kovacs,A.L.,Juhasz,G.,Maroy,P.,Vigh,L.,Balogh,G.,Sinka,R.,2016.Reduced expression of CDP-DAG synthase changes lipid composition and leads to male sterility in Drosophila.Open Biol.6,50169.
Lemmon,M.A.,Ferguson,K.M.,O'Brien,R.,Sigler,P.B.,Schlessinger,J.,1995.Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain.Proc.Natl.Acad.Sci.U.S.A.92,10472e10476.
Liu,Y.,Wang,W.,Shui,G.,Huang,X.,2014.CDP-diacylglycerol synthetase coordinates cell growth and fat storage through phosphatidylinositol metabolism and the insulin pathway.PLoS Genet.10,e1004172.
Petryk,A.,Warren,J.T.,Marques,G.,Jarcho,M.P.,Gilbert,L.I.,Kahler,J.,Parvy,J.P.,Li,Y.,Dauphin-Villemant,C.,O'Connor,M.B.,2003.Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20-hydroxyecdysone.Proc.Natl.Acad.Sci.U.S.A.100,13773e13778.
Raghu,P.,Coessens,E.,Manifava,M.,Georgiev,P.,Pettitt,T.,Wood,E.,GarciaMurillas,I.,Okkenhaug,H.,Trivedi,D.,Zhang,Q.,Razzaq,A.,Zaid,O.,Wakelam,M.,O'Kane,C.J.,Ktistakis,N.,2009.Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels.J.Cell Biol.185,129e145.
Thummel,C.S.,1996.Flies on steroids-Drosophila metamorphosis and the mechanisms of steroid hormone action.Trends Genet.12,306e310.
Venkatesh,K.,Hasan,G.,1997.Disruption of the IP3 receptor gene of Drosophila affects larval metamorphosis and ecdysone release.Curr.Biol.7,500e509.
Wu,L.,Niemeyer,B.,Colley,N.,Socolich,M.,Zuker,C.S.,1995.Regulation of PLC-mediated signalling in vivo by CDP-diacylglycerol synthase.Nature 373,216e222.
Yamanaka,N.,Marques,G.,O'Connor,M.B.,2015.Vesicle-mediated steroid hormone secretion in Drosophila melanogaster.Cell 163,907e919.
Yamanaka,N.,Rewitz,K.F.,O'Connor,M.B.,2013.Ecdysone control of developmental transitions:lessons from Drosophila research.Annu.Rev.Entomol.58,497e516.
Colombani,J.,Bianchini,L.,Layalle,S.,Pondeville,E.,Dauphin-Villemant,C.,Antoniewski,C.,Carre,C.,Noselli,S.,Leopold,P.,2005.Antagonistic actions of ecdysone and insulins determine final size in Drosophila.Science 310,667e670.
Gilbert,L.I.,Rybczynski,R.,Warren,J.T.,2002.Control and biochemical nature of the ecdysteroidogenic pathway.Annu.Rev.Entomol.47,883e916.
Gronke,S.,Mildner,A.,Fellert,S.,Tennagels,N.,Petry,S.,Muller,G.,Jackle,H.,Kuhnlein,R.P.,2005.Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila.Cell Metabol.1,323e330.
Huang,X.,Suyama,K.,Buchanan,J.,Zhu,A.J.,Scott,M.P.,2005.A Drosophila model of the Niemann-Pick type C lysosome storage disease:dnpc1a is required for molting and sterol homeostasis.Development 132,5115e5124.
Huang,X.,Warren,J.T.,Buchanan,J.,Gilbert,L.I.,Scott,M.P.,2007.Drosophila Niemann-Pick type C-2 genes control sterol homeostasis and steroid biosynthesis:a model of human neurodegenerative disease.Development 134,3733e3742.
Huang,X.,Warren,J.T.,Gilbert,L.I.,2008.New players in the regulation of ecdysone biosynthesis.J.Genet.Genomics 35,1e10.
Laurinyecz,B.,Peter,M.,Vedelek,V.,Kovacs,A.L.,Juhasz,G.,Maroy,P.,Vigh,L.,Balogh,G.,Sinka,R.,2016.Reduced expression of CDP-DAG synthase changes lipid composition and leads to male sterility in Drosophila.Open Biol.6,50169.
Lemmon,M.A.,Ferguson,K.M.,O'Brien,R.,Sigler,P.B.,Schlessinger,J.,1995.Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain.Proc.Natl.Acad.Sci.U.S.A.92,10472e10476.
Liu,Y.,Wang,W.,Shui,G.,Huang,X.,2014.CDP-diacylglycerol synthetase coordinates cell growth and fat storage through phosphatidylinositol metabolism and the insulin pathway.PLoS Genet.10,e1004172.
Petryk,A.,Warren,J.T.,Marques,G.,Jarcho,M.P.,Gilbert,L.I.,Kahler,J.,Parvy,J.P.,Li,Y.,Dauphin-Villemant,C.,O'Connor,M.B.,2003.Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20-hydroxyecdysone.Proc.Natl.Acad.Sci.U.S.A.100,13773e13778.
Raghu,P.,Coessens,E.,Manifava,M.,Georgiev,P.,Pettitt,T.,Wood,E.,GarciaMurillas,I.,Okkenhaug,H.,Trivedi,D.,Zhang,Q.,Razzaq,A.,Zaid,O.,Wakelam,M.,O'Kane,C.J.,Ktistakis,N.,2009.Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels.J.Cell Biol.185,129e145.
Thummel,C.S.,1996.Flies on steroids-Drosophila metamorphosis and the mechanisms of steroid hormone action.Trends Genet.12,306e310.
Venkatesh,K.,Hasan,G.,1997.Disruption of the IP3 receptor gene of Drosophila affects larval metamorphosis and ecdysone release.Curr.Biol.7,500e509.
Wu,L.,Niemeyer,B.,Colley,N.,Socolich,M.,Zuker,C.S.,1995.Regulation of PLC-mediated signalling in vivo by CDP-diacylglycerol synthase.Nature 373,216e222.
Yamanaka,N.,Marques,G.,O'Connor,M.B.,2015.Vesicle-mediated steroid hormone secretion in Drosophila melanogaster.Cell 163,907e919.
Yamanaka,N.,Rewitz,K.F.,O'Connor,M.B.,2013.Ecdysone control of developmental transitions:lessons from Drosophila research.Annu.Rev.Entomol.58,497e516.