血红蛋白校正对肺一氧化碳弥散量结果的影响
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- 论文作者：闫冬梅 ; 何馨 ; 赵旭娟
- 年：2017
- 作者机构：首都医科大学附属北京友谊医院;
- 论文关键词：肺功能测试 ; 血红蛋白校正 ; 肺一氧化碳弥散量
- 英文论文关键词：Lung function measurements ; Hemoglobin correction ; Carbon monoxide diffusing capacity of the lungs
- 会议召开时间：2017-05-26
- 会议录名称：2017年《中国组织化学与细胞化学杂志》临床研讨会论文集
- 语种：中文
- 分类号：R563
- 学会代码：ZHXB
- 会议名称：2017年《中国组织化学与细胞化学杂志》临床研讨会
- 会议地点：中国湖北武汉
- 主办单位：《中国组织化学与细胞化学杂志》社有限公司
- 学会名称：《中国组织化学与细胞化学杂志》社有限公司
- 页数：2
- 文件大小：250k
- 原文格式：O
- 会议级别：全国
摘要
目的:探讨血红蛋白校正对肺一氧化碳弥散量测量结果的影响。方法:对比性分析63例患者经血红蛋白校正前后的肺一氧化碳弥散量测量结果。结果:经血红蛋白校正前,患者肺一氧化碳弥散量为61.31±19.05,而经血红蛋白校正后,患者肺一氧化碳弥散量为62.73±19.15,二者有显著差异(p<0.05);男性患者校正前后肺一氧化碳弥散量分别为55.32±19.61及57.22±20.23,女性患者校正前后肺一氧化碳弥散量分别为69.84±14.74及70.56±14.54,均存在差异(男性p<0.05,女性p<0.1)。结论:肺一氧化碳弥散量经血红蛋白校正前后有显著差异,与性别及血红蛋白含量无关,临床上肺一氧化碳弥散量测定的结果应进行血红蛋白校正。
Objective:To explore the influence of adjustment for hemoglobin on the measurement of diffusing capacity of the lungs for carbon monoxide(DL,CO).Method:DL,CO befor and after adjustment for hemoglobin were compared in 63 subjects.Result:There was significandy differenct in DL,CO before and after adjustment for hemoglobin(61.31 ± 19.05 vs 62.73 ± 19.15,P < 0.05).Male and female' s DL,CO have variation,before and after adjustment for hemoglobin((male:55.32 ± 19.61 vs 57.22 ± 20.23,P < 0.05),(female:69.84 ± 14.74 vs 70.56 ± 14.54,P < 0.1)).Conclusion:There is a significant difference of DL,CO,before and after adjustment for hemoglobin.This difference has nothing to do with gender and hemoglobin content.The DL,CO measurement need to be adjusted for hemoglobin.
Objective:To explore the influence of adjustment for hemoglobin on the measurement of diffusing capacity of the lungs for carbon monoxide(DL,CO).Method:DL,CO befor and after adjustment for hemoglobin were compared in 63 subjects.Result:There was significandy differenct in DL,CO before and after adjustment for hemoglobin(61.31 ± 19.05 vs 62.73 ± 19.15,P < 0.05).Male and female' s DL,CO have variation,before and after adjustment for hemoglobin((male:55.32 ± 19.61 vs 57.22 ± 20.23,P < 0.05),(female:69.84 ± 14.74 vs 70.56 ± 14.54,P < 0.1)).Conclusion:There is a significant difference of DL,CO,before and after adjustment for hemoglobin.This difference has nothing to do with gender and hemoglobin content.The DL,CO measurement need to be adjusted for hemoglobin.
引文
[1]Kimmel EC,Carpenter RL,Reboulet JE,et al.A physiological model for predicting carboxyhemoglobin formation form exposure to carbon monoxide in rats.J appl Physiol,1999,86(6):1977-1983.
[2]穆魁津,林友华.肺功能测定原理与临床应用.第1版.北京:北京医科大学中国协和医科大学联合出版社,1992.142-143.
[3]阎日成,王秀云.血红蛋白下降、吸烟对肺一氧化碳弥散功能的影响.肿瘤研究与临床,2002,14(5):353.
[4]何权瀛,马保义.36例慢性阻塞性肺气肿患者一氧化碳弥散量及其与Hb含量的关系.中华结核和呼吸杂志,1997,20(4):254.
[5]郝峰英,余秉翔,曹璐,等.贫血对肺一氧化碳弥散量的影响.中国误诊学杂志,2004,9(4):1364-1365.
[6]American Thoracic Rociety.Single-breath carbon monoxide diffusing capacity(transfer factor):recommendations for a standard technique 1995update.Am J Respir Crit Care Med 152:2185-2198,1995.
[7]Crapo RO,Jensen RL,Wanger JS.Single-breath carbon monoxide diffusing capacity.Clin Chest Med 22:637-649,2001.
[8]N.Maclntyre,R.O.Crapo,G.Viegi,et al.Standardisation of the single-breath determination of carbon monoxide uptake in the lung.Eur Respir J 2005;26:720-735.
[2]穆魁津,林友华.肺功能测定原理与临床应用.第1版.北京:北京医科大学中国协和医科大学联合出版社,1992.142-143.
[3]阎日成,王秀云.血红蛋白下降、吸烟对肺一氧化碳弥散功能的影响.肿瘤研究与临床,2002,14(5):353.
[4]何权瀛,马保义.36例慢性阻塞性肺气肿患者一氧化碳弥散量及其与Hb含量的关系.中华结核和呼吸杂志,1997,20(4):254.
[5]郝峰英,余秉翔,曹璐,等.贫血对肺一氧化碳弥散量的影响.中国误诊学杂志,2004,9(4):1364-1365.
[6]American Thoracic Rociety.Single-breath carbon monoxide diffusing capacity(transfer factor):recommendations for a standard technique 1995update.Am J Respir Crit Care Med 152:2185-2198,1995.
[7]Crapo RO,Jensen RL,Wanger JS.Single-breath carbon monoxide diffusing capacity.Clin Chest Med 22:637-649,2001.
[8]N.Maclntyre,R.O.Crapo,G.Viegi,et al.Standardisation of the single-breath determination of carbon monoxide uptake in the lung.Eur Respir J 2005;26:720-735.