比较全直肠系膜切除术和传统手术治疗直肠癌的疗效
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- 论文作者：杨广胜 ; 闻兆章 ; 黄彬 ; 高向东 ; 沈烨
- 年：2016
- 作者机构：江苏大学附属澳洋医院胃肠外科;
- 论文关键词：全直肠系膜切除术 ; 传统手术 ; 直肠癌
- 英文论文关键词：Total mesorectal excision ; traditional surgery ; rectal cancer
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R735.37
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：2
- 文件大小：1845k
- 原文格式：D
- 会议级别：全国
摘要
目的:探讨全直肠系膜切除术和传统手术治疗直肠癌的临床疗效并对其进行比较分析。方法:选择我院2008年5月至2016年5月收治的直肠癌患者86例,将其随机分为两组,分别为观察组和对照组,每组患者各43例。观察组患者采取全直肠系膜切除术治疗,对照组患者采取传统手术治疗。结果:观察组患者的术中出血量、局部复发率、术后感染率和吻合口瘘发生率均显著低于对照组患者,观察组患者的手术时间、术后住院时间和肛门排气时间均显著短于对照组患者,观察组患者的5年生存率显著高于对照组患者,差异均有统计学意义(P<0.05)。经PCR定量分析,本次研究组结肠癌患者肠道粪便中双歧杆菌、乳酸杆菌、大肠杆菌、粪肠球菌数量较以往资料明显减少,p<0.05,差异有统计学意义。结论:全直肠系膜切除术治疗直肠癌患者可有效提高患者的生存率,使患者的生理功能在最大程度上得以保留,值得在临床上推广应用。
Objective: To investigate the clinical effect of total mesorectal excision and conventional surgical treatment of rectal cancer and comparative analysis of the. Methods: 86 cases of rectal cancer in our hospital from May 2008 to May 2016 were randomly divided into two groups, the observation group and the control group, 43 cases in each group. The observationgroup patients were treated with total mesorectal excision in the treatment, control group were treated by traditional surgery. Results: the amount of bleeding, observation group of patients withlocal recurrence rate and the incidence of postoperative infection and anastomotic leakage were significantly lower than the control group. The operation time, patients after hospitalization time andanal exhaust time were significantly shorter than the control group, to observe the 5 year survival rate of patients was signiifcantly higher than in the control group, the differences were statisticallysignificant(P < 0.05). By PCR quantitative analysis, this study group of colon cancer patients intestinal stool in the stool, the number of Lactobacillus, Escherichia coli, fecal, compared with theprevious data significantly reduced, p<0.05, the difference was statistically significant. Conclusion: total mesorectal excision for rectal cancer patients can effectively improve the survival rate ofpatients, the physiological function of patients with preserved to the maximum extent, it is worthy of clinical application.
Objective: To investigate the clinical effect of total mesorectal excision and conventional surgical treatment of rectal cancer and comparative analysis of the. Methods: 86 cases of rectal cancer in our hospital from May 2008 to May 2016 were randomly divided into two groups, the observation group and the control group, 43 cases in each group. The observationgroup patients were treated with total mesorectal excision in the treatment, control group were treated by traditional surgery. Results: the amount of bleeding, observation group of patients withlocal recurrence rate and the incidence of postoperative infection and anastomotic leakage were significantly lower than the control group. The operation time, patients after hospitalization time andanal exhaust time were significantly shorter than the control group, to observe the 5 year survival rate of patients was signiifcantly higher than in the control group, the differences were statisticallysignificant(P < 0.05). By PCR quantitative analysis, this study group of colon cancer patients intestinal stool in the stool, the number of Lactobacillus, Escherichia coli, fecal, compared with theprevious data significantly reduced, p<0.05, the difference was statistically significant. Conclusion: total mesorectal excision for rectal cancer patients can effectively improve the survival rate ofpatients, the physiological function of patients with preserved to the maximum extent, it is worthy of clinical application.
引文
[1]姚学清,卿三华,黄详成,等.直肠癌全直肠系膜切除术与传统直肠癌根治术疗效对比研究[J].中国现代普通外科进展,2009,6(1):52-54.
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[4]周件峰.全直肠系膜切除术和传统手术方法治疗直肠癌的临床疗效比较[J].中外医学研究,2012,10(5):36-37.
[5]余江,张策,王亚楠,等.腹腔镜直肠癌全直肠系膜切除术中无瘤技术的探讨[J].腹腔镜外科杂志,2010,15(6):65-67.
[6]Orlandi RR,Kenndy DW.Revision endoscopic frontal sinus sur gery.Otolaryngol.Clin North Am.2011,34(1):77-90.
[7]Koreas G B,editor.Combine traditional Chinese and Western medicine clinical results.Rev Endocr Metab Disord,2013.73.
[8]Kew J,Rees GL,Close D.Multiplanar reconstructed computed tomography images improves depiction and understanding of the anatomy of the frontal sinus and recess.Am J Rhinol 2013.16(2):19-23.
[9]Shelbourne KD,Brueckmann RR.Rush-pin fiXation of suprac ondylar and intercondylar fractures of the femur.J Bone Joint Surg Am,2014,64(2):161 169.
[10]Stammberger HR,Kenney DW.Paranasal sinuses:Anatomicte rminology and nomenclature.Ann Oto Rhinol Laryngol,2013,167(suppl):7 16.
[2]余江,张策,王亚楠,等.腹腔镜与开腹全直肠系膜切除术治疗中低位直肠癌的同期临床对照研究[J].中华胃肠外科杂志,2009,14(6):671-672.
[3]余杰雄,叶勇,陈学中,等.全直肠系膜切除术语传统直肠癌根治术治疗直肠癌疗效比较[J].中华胃肠外科杂志,2009,4(2):116-118.
[4]周件峰.全直肠系膜切除术和传统手术方法治疗直肠癌的临床疗效比较[J].中外医学研究,2012,10(5):36-37.
[5]余江,张策,王亚楠,等.腹腔镜直肠癌全直肠系膜切除术中无瘤技术的探讨[J].腹腔镜外科杂志,2010,15(6):65-67.
[6]Orlandi RR,Kenndy DW.Revision endoscopic frontal sinus sur gery.Otolaryngol.Clin North Am.2011,34(1):77-90.
[7]Koreas G B,editor.Combine traditional Chinese and Western medicine clinical results.Rev Endocr Metab Disord,2013.73.
[8]Kew J,Rees GL,Close D.Multiplanar reconstructed computed tomography images improves depiction and understanding of the anatomy of the frontal sinus and recess.Am J Rhinol 2013.16(2):19-23.
[9]Shelbourne KD,Brueckmann RR.Rush-pin fiXation of suprac ondylar and intercondylar fractures of the femur.J Bone Joint Surg Am,2014,64(2):161 169.
[10]Stammberger HR,Kenney DW.Paranasal sinuses:Anatomicte rminology and nomenclature.Ann Oto Rhinol Laryngol,2013,167(suppl):7 16.