乳酸脱氢酶、羟丁酸脱氢酶、碱性磷酸酶与谷氨酰基转移酶在慢性髓系白血病中表达及意义
详细信息 查看官网全文
- 英文论文题名：Expression and Role of LDH、HBDH、ALP and GGT in Chronic Myelogenous Leukemia
- 论文作者：申娜 ; 贺靖澜 ; 潘丽兰 ; 周晨光 ; 于艳芳
- 英文论文作者：Shen Na ; He Jing-lan ; Pan Li-lan ; Zhou Chen-guang ; Yu Yan-fang ; Affiliated Hospital of Hebei University of Engineering
- 年：2017
- 作者机构：河北工程大学附属医院;
- 论文关键词：乳酸脱氢酶 ; 羟丁酸脱氢酶 ; 碱性磷酸酶 ; 谷氨酰基转移酶慢性髓系白血病
- 英文论文关键词：LDH ; HBDH ; ALP ; GGT ; CML ; ELISA
- 会议召开时间：2017-05-26
- 会议录名称：2017年《中国组织化学与细胞化学杂志》临床研讨会论文集
- 语种：中文
- 分类号：R733.72
- 学会代码：ZHXB
- 会议名称：2017年《中国组织化学与细胞化学杂志》临床研讨会
- 会议地点：中国湖北武汉
- 主办单位：《中国组织化学与细胞化学杂志》社有限公司
- 学会名称：《中国组织化学与细胞化学杂志》社有限公司
- 页数：1
- 文件大小：109k
- 原文格式：O
- 会议级别：全国
摘要
目的:本研究探讨乳酸脱氢酶、羟丁酸脱氢酶、碱性磷酸酶与谷氨酰基转移酶在慢性髓系白血病各期中的表达及意义。方法:将观察对象分为为正常对照组、CML-CP组,CML-BP/AP组。用生化法检测讨乳酸脱氢酶、羟丁酸脱氢酶、碱性磷酸酶与谷氨酰基转移酶水平。结果:CMLCP组LDH、HBDH、ALP、GGT水平明显高于对照组,差异具有显著性;CML-AP/BP组LDH、HBDH、ALP、GGT水平显著高于CML-CP组;CML-AP/BP组患者LDH、HBDH与骨髓内幼稚细胞数呈正相关,CML-CP组患者LDH、HBDH与外周血白细胞总数正相关。结论:CML患者血清LDH、HBHD、ALP、GGT水平与患者的病情直接相关,有助于更准确的判断疾病预后。
Objective:In this study to investigate the expression and significance of LDH、HBDH、ALP and GGT in control group and in different phases of CML.Method:This study includes the control group,CML-CP group and CML-BP/AP group.The chemical method was used to detect expression of LDH、HBDH、ALP and GGT in control group and in different phases of CML.Result:Expression of LDH、HBDH、ALP and GGT in CML-CP group was significantly higher than that in control group,expression of LDH、HBDH、ALP and GGT in CML-BP/AP group was notably higher than that in CML-CP group.LDH and HBDH had positive correlation with the bone marrow blasts in the CML-BP/AP group.In CML-CP group LDH and HBDH are relationship with the leukocyte count in peripheral blood.Conclusion:In CML patients,serum LDH、HBHD、ALP、GGT are closely relate with pathogenetic condition,which may be a key factors to judge the development of CML.
Objective:In this study to investigate the expression and significance of LDH、HBDH、ALP and GGT in control group and in different phases of CML.Method:This study includes the control group,CML-CP group and CML-BP/AP group.The chemical method was used to detect expression of LDH、HBDH、ALP and GGT in control group and in different phases of CML.Result:Expression of LDH、HBDH、ALP and GGT in CML-CP group was significantly higher than that in control group,expression of LDH、HBDH、ALP and GGT in CML-BP/AP group was notably higher than that in CML-CP group.LDH and HBDH had positive correlation with the bone marrow blasts in the CML-BP/AP group.In CML-CP group LDH and HBDH are relationship with the leukocyte count in peripheral blood.Conclusion:In CML patients,serum LDH、HBHD、ALP、GGT are closely relate with pathogenetic condition,which may be a key factors to judge the development of CML.
引文