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复合抗菌肽对断奶仔猪生长性能及健康状况的影响
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摘要
本研究旨在评估复合抗菌肽对断奶仔猪生长性能和健康状况的影响。试验期共28天,36头断奶仔猪(平均体重10.58±0.99 kg)随机分为3个处理,对照组饲喂基础饲粮;抗生素组在基础饲粮中添加硫酸粘杆菌素20mg/kg和吉他霉素50mg/kg;复合抗菌肽组在基础饲粮中添加400mg/kg抗菌肽。结果表明:复合抗菌肽组相比于对照组和抗生素组显著提高了8-14天和15-21天的仔猪平均日增重(P<0.05);复合抗菌肽组较对照组显著提高了全期的饲料转化率(P<0.05);复合抗菌肽组和抗生素组较对照组显著降低了1-7天的仔猪腹泻率(P<0.05);复合抗菌肽组较对照组显著增加双歧杆菌和乳酸杆菌的数量(P<0.05),减少大肠杆菌数量(P≮0.05),显著提高了干物质的表观消化率(P<0.05)。以上研究结果表明,饲喂复合抗菌肽可以改善断奶仔猪的生长性能和健康状况。
This study was conducted to evaluate the effects of composite antimicrobial peptide(CAMP) on growth performance and health status in weaned piglets.Over 28 days,36 weaned piglets(body weight,10.58 ± 0.99 kg)underwent 3 treatments:negative control(NC,basal diet),positive control(PC,basal diet + 20mg/kg Colistin Sulphate +50mg/kg kitasamycin),and composite antimicrobial peptide treatment(CAMP,basal diet with 400 mg/kg CAMP).Average daily gain of piglets fed the CAMP diet was greater(P<0.05) than that of piglets fed the PC or NC diet during day 8-14 or 15-21,respectively.The overall feed conversion ratio of piglets fed the CAMP diet was lower(P<0.05) than that of piglets fed the NC diet.Diarrhea rates of piglets fed the CAMP or PC diet were lower(P<0.05) than those of NC-fed piglets during day 1-7.Apparent total tract digestibility for dry matter in CAMP-fed piglets was greater(P<0.05)than that of NC-fed piglets.In the CAMP group,Lactobacillus and Bifidobacterium counts were greater(P<0.05) and E.coli counts were lower(P<0.05) than numbers for the NC group.Our results suggest that dietary CAMP can improve growth performance and health status in weaned piglets.
引文
AOAC.2000.Official Methods of Analysis.17~(th)edn.Association of Official Analytical Chemists,Gaithersburg,MD,USA.
    Andersen AS,Sandvang D,Schnorr KM,Kruse T,Neve S,Joergensen B,Krogfelt KA.2010.A novel approach to the antimicrobial activity of maggot debridement therapy.Journal of Antimicrobial Chemotherapy 65,1646-1654.

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