用生物标志物评价饮用水源污染的健康风险
详细信息 查看官网全文
- 英文论文题名：The Risk Assessment on the Pollution of Drinking Water Sources with Biomarker
- 论文作者：厉以强
- 英文论文作者：LI Yiqiang ; Environmental Monitoring Center of Jiangsu Province
- 年：2015
- 作者机构：江苏省环境监测中心;
- 论文关键词：生物标志物 ; 水源地 ; 风险评价 ; 环境诱变剂
- 英文论文关键词：Biomarker ; Sources of drinking water ; Risk assessment ; Environmental mutagen
- 会议召开时间：2015-11-26
- 会议录名称：2015年水资源生态保护与水污染控制研讨会论文集
- 语种：中文
- 分类号：X824
- 学会代码：HJKP
- 会议名称：2015年水资源生态保护与水污染控制研讨会
- 会议地点：中国海南海口
- 主办单位：中国环境科学学会、哈尔滨师范大学
- 学会名称：中国环境科学学会
- 页数：4
- 文件大小：692k
- 原文格式：D
- 会议级别：全国
摘要
针对肿瘤高发区饮用水污染的健康风险评价问题,本文提出可用生物标志物检测水中的"环境诱变剂量",作为评价水体中有毒有害污染物潜在遗传危害的综合指标,并简要介绍了生物标志物在国内外的研究动态及其在环境监测、评价与管理中的应用前景。
Facing the issue of risk assessment on drinking water pollution in high-morbidity-district of cancer, this paper pointed out that the Genotoxic Effects of Environ- mental Mutagen, GEEM, in water can be detected by biomarker. This biomarker method can be regarded as the aggregate index to evaluate the potential hereditary damage on the poisonous and harmful pollutants in water, the paper also briefly introduced the research trend on biomarker at home and abroad as well as its application prospects in environmental monitoring, assessment and management.
Facing the issue of risk assessment on drinking water pollution in high-morbidity-district of cancer, this paper pointed out that the Genotoxic Effects of Environ- mental Mutagen, GEEM, in water can be detected by biomarker. This biomarker method can be regarded as the aggregate index to evaluate the potential hereditary damage on the poisonous and harmful pollutants in water, the paper also briefly introduced the research trend on biomarker at home and abroad as well as its application prospects in environmental monitoring, assessment and management.
引文
[1]曾昭华,曾雪萍.中国癌症与土壤环境中锑元素的关系.江苏环境科技,2002,15(1):28-29
[2]中国环境优先监测研究课题组.环境优先污染物.北京:中国环境科学出版社,1989
[3]朱惠刚.水中有机化学污染物对人体影响评价.中国环境科学,1987,7(4):67
[4]印木泉主编.遗传毒理学(现代遗传学丛书).北京:科学出版社,2002:456
[5]万斌.生态毒理学中生物标志物研究进展.国外医学卫生学分册,2000,27(2):110-114
[6]Goksoyr A.,Beyer J.,Egaas E.,et al.Biomarker Responses in Flounder(Platichthys flesus)and their use in Pollution Monitoring.Mar.Pollut.Bull.1996,33(1-6):36-45
[7]王海黎,陶澍.生物标志物在水环境研究中的应用.中国环境科学,1999,19(5):421-426
[8]Vandenberg JJ.Risk Assessment and Research:an Essential Link.Toxicol.Lett.1995,79(1-3):17-22
[9]Speit G,Hanelt S,Helbig R,et al.Detection of DNA effects in human cells with the comet assay and their relevance for mutagenesis.Toxicol Lett.1996,88(1-3):91-98
[10]Avishai N,Rabinowitz C,Moiseeva E,et al.Genotoxicity of the Kishon River,Israel:the application of an in vitro cellular assay.Mutat Res.2002,518(1):21-37
[11]Kammann U.,Caparro Riggers J.,Theobald N.,et al.Genotoxic Poternial of Marine Sediments from the North Sea.Mutat.Res.2000,467(2):161-168
[12]Guzzella L.Evaluation of Genotoxicity of Italian Lakewater for Human Consumption.A Case Study in Lombardy.Toxicol.Environ.Chem.1999,73(1-2):81-92
[13]Clements C.,Ralph S.,and Petras M..Genotoxicity of Select Herbicides in Rana catesbeiana Tadpoles Using the Alkaline Single-Cell Gel DNA Electrophoresis(Comet)Assay.Environ Mol Mutagen.1997,29(3):277-288
[14]Chang L.W.,Meier J.R.,Daniel F.B.,et al.Gene Expression and Genetic Damage Indicators in Fish Exposed to Varying Stream Conditions in a Midwestern Watershed.2001.
[15]Mitchelmore CL,Chipman JK.DNA strand breakage in aquatic organisms and the potential value of the comet assay in environmental monitoring.Mutat Res.1998,399(2):135-147
[16]Hartmann A.,Speit G..Comparative investigations of the genotoxic effect of metals in the single cell gel assay and the sister chromatid exchange test.Environ.Mol.Mutag.1994,23:299-305
[17]候剑秋.广州市区珠江河段水污染情况浅析.生态科学,1993,12:14-20
[18]李东,吴惠勤,黄芳,等.珠江广州河段水中有机污染物的GC-MS分析.分析测试学报,2002,21(3):86-88
[19]陈红红.水厂原水与出厂水有机污染物的分析比较.环境与健康杂志,2002,19(4):319-322
[20]薛峰,薛念涛.环境毒理学与环境监测.环境监测管理与技术,2000,12(3):17-19
[21]张国栋,钟远,封少龙,等.扬中市地表水的致突变性研究.重庆环境科学,2000,22(3):58-59
[22]范春,杨艳梅,佟延功,等.松花江四方台水源地水体有机提取物致癌活性的实验研究.中华预防医学杂志,2001,35(6):401-403
[23]王菊香,韩永霞,高玉梅,等.某市水中有机提取物对人外周血淋巴细胞DNA的损伤作用.环境与健康杂志,2002,19(2):114-116
[24]邱志群,舒为群,田怀军.4种饮用水中有机提取物的遗传毒性研究.中国公共卫生,2003,19(6):692-694
[25]赵影,杨志平,王志强,等.巢湖水藻类毒性及对饮用水水质影响.环境与健康杂志,2003,20(4):219-222
[2]中国环境优先监测研究课题组.环境优先污染物.北京:中国环境科学出版社,1989
[3]朱惠刚.水中有机化学污染物对人体影响评价.中国环境科学,1987,7(4):67
[4]印木泉主编.遗传毒理学(现代遗传学丛书).北京:科学出版社,2002:456
[5]万斌.生态毒理学中生物标志物研究进展.国外医学卫生学分册,2000,27(2):110-114
[6]Goksoyr A.,Beyer J.,Egaas E.,et al.Biomarker Responses in Flounder(Platichthys flesus)and their use in Pollution Monitoring.Mar.Pollut.Bull.1996,33(1-6):36-45
[7]王海黎,陶澍.生物标志物在水环境研究中的应用.中国环境科学,1999,19(5):421-426
[8]Vandenberg JJ.Risk Assessment and Research:an Essential Link.Toxicol.Lett.1995,79(1-3):17-22
[9]Speit G,Hanelt S,Helbig R,et al.Detection of DNA effects in human cells with the comet assay and their relevance for mutagenesis.Toxicol Lett.1996,88(1-3):91-98
[10]Avishai N,Rabinowitz C,Moiseeva E,et al.Genotoxicity of the Kishon River,Israel:the application of an in vitro cellular assay.Mutat Res.2002,518(1):21-37
[11]Kammann U.,Caparro Riggers J.,Theobald N.,et al.Genotoxic Poternial of Marine Sediments from the North Sea.Mutat.Res.2000,467(2):161-168
[12]Guzzella L.Evaluation of Genotoxicity of Italian Lakewater for Human Consumption.A Case Study in Lombardy.Toxicol.Environ.Chem.1999,73(1-2):81-92
[13]Clements C.,Ralph S.,and Petras M..Genotoxicity of Select Herbicides in Rana catesbeiana Tadpoles Using the Alkaline Single-Cell Gel DNA Electrophoresis(Comet)Assay.Environ Mol Mutagen.1997,29(3):277-288
[14]Chang L.W.,Meier J.R.,Daniel F.B.,et al.Gene Expression and Genetic Damage Indicators in Fish Exposed to Varying Stream Conditions in a Midwestern Watershed.2001.
[15]Mitchelmore CL,Chipman JK.DNA strand breakage in aquatic organisms and the potential value of the comet assay in environmental monitoring.Mutat Res.1998,399(2):135-147
[16]Hartmann A.,Speit G..Comparative investigations of the genotoxic effect of metals in the single cell gel assay and the sister chromatid exchange test.Environ.Mol.Mutag.1994,23:299-305
[17]候剑秋.广州市区珠江河段水污染情况浅析.生态科学,1993,12:14-20
[18]李东,吴惠勤,黄芳,等.珠江广州河段水中有机污染物的GC-MS分析.分析测试学报,2002,21(3):86-88
[19]陈红红.水厂原水与出厂水有机污染物的分析比较.环境与健康杂志,2002,19(4):319-322
[20]薛峰,薛念涛.环境毒理学与环境监测.环境监测管理与技术,2000,12(3):17-19
[21]张国栋,钟远,封少龙,等.扬中市地表水的致突变性研究.重庆环境科学,2000,22(3):58-59
[22]范春,杨艳梅,佟延功,等.松花江四方台水源地水体有机提取物致癌活性的实验研究.中华预防医学杂志,2001,35(6):401-403
[23]王菊香,韩永霞,高玉梅,等.某市水中有机提取物对人外周血淋巴细胞DNA的损伤作用.环境与健康杂志,2002,19(2):114-116
[24]邱志群,舒为群,田怀军.4种饮用水中有机提取物的遗传毒性研究.中国公共卫生,2003,19(6):692-694
[25]赵影,杨志平,王志强,等.巢湖水藻类毒性及对饮用水水质影响.环境与健康杂志,2003,20(4):219-222