Comparative Genome Analyses Reveal Distinct Modes of Host-specialization Between Dicot and Monocot Powdery Mildew

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• 英文论文题名：Comparative Genome Analyses Reveal Distinct Modes of Host-specialization Between Dicot and Monocot Powdery Mildew
• 论文作者：WU Ying ; MA Xian-feng ; PAN Zhi-yong ; KALE Shiv ; SONG Yi ; XIAO Shun-yuan
• 英文论文作者：WU Ying ; MA Xian-feng ; PAN Zhi-yong ; KALE Shiv ; SONG Yi ; XIAO Shun-yuan ; Institute of Biosciences and Biotechnology Research & Department of Plant Science and Landscape Architecture ; University of Maryland College Park ; Key Laboratory of Horticultural Plant Biology of Ministry of Education ; Huazhong Agricultural University ; Virginia Bioinformatics Institute ; Virginia Tech
• 年：2016
• 作者机构：Institute of Biosciences and Biotechnology Research & Department of Plant Science and Landscape Architecture,University of Maryland College Park;Key Laboratory of Horticultural Plant Biology of Ministry of Education,Huazhong Agricultural University;Virginia Bioinformatics Institute,Virginia Tech;
• 会议召开时间：2016-08-05
• 会议录名称：中国植物病理学会2016年学术年会论文集
• 英文会议录名称：Proceedings of the Annual Meeting of Chinese Society for Plant Pathology(2016)
• 语种：英文
• 分类号：S432.4
• 学会代码：ZGVS
• 会议名称：中国植物病理学会2016年学术年会
• 会议地点：中国江苏南京
• 主办单位：中国植物病理学会
• 学会名称：中国植物病理学会
• 页数：1
• 文件大小：48k
• 原文格式：O
• 会议级别：全国

摘要

Monocot powdery mildew(PM) fungi such as Blumeria graminis f.sp.hordei(Bgh)infectious on barley and B.graminis f.sp.tritici(Bgt) infectious on wheat exhibit extremely high-level of host-specialization.By contrast,many dicot PM fungi display rather broad host ranges.To understand why different PM fungi adopt distinct modes of host-adaption,we sequenced the genomes of four dicot PM strains(three Golovinomyces and one Oidium) and conducted comparative sequence analyses along with the genomes of Bgh,Bgt and Erysiphe necator(infectious on grapevine) available from the Genbank.While 3 129 genes are found in all seven genomes(thus they are conserved PM genes),-50%are lineage-specific,of which 116 ~ 534 are genes encoding candidate secreted effector proteins(CSEPs).Interestingly,while the two monocot PM fungi possess up to 534 CSEPs with several families containing up to 21 members,all the five dicot PM fungi have only 116 ~ 178 CSEPs with limited gene amplification.These two evolutionary patterns concerning PM CSEPs coincide with the contrasting modes of their host-adaption:the monocot PM fungi show a high-level of host specialization,likely reflecting an advanced host-pathogen arms-race,whereas the dicot PM fungi tend to practice polyphagy,which has presumably lessened the selective pressure for escalating an arms-race with a particular host.Strikingly,the tomato PM Oidium neolycopersici has a genome only half the size of other PM genomes,despite having a similar number of genes,suggesting that 0.neolycopersici has followed a unique genome evolutionary path.
Monocot powdery mildew(PM) fungi such as Blumeria graminis f.sp.hordei(Bgh)infectious on barley and B.graminis f.sp.tritici(Bgt) infectious on wheat exhibit extremely high-level of host-specialization.By contrast,many dicot PM fungi display rather broad host ranges.To understand why different PM fungi adopt distinct modes of host-adaption,we sequenced the genomes of four dicot PM strains(three Golovinomyces and one Oidium) and conducted comparative sequence analyses along with the genomes of Bgh,Bgt and Erysiphe necator(infectious on grapevine) available from the Genbank.While 3 129 genes are found in all seven genomes(thus they are conserved PM genes),-50%are lineage-specific,of which 116 ~ 534 are genes encoding candidate secreted effector proteins(CSEPs).Interestingly,while the two monocot PM fungi possess up to 534 CSEPs with several families containing up to 21 members,all the five dicot PM fungi have only 116 ~ 178 CSEPs with limited gene amplification.These two evolutionary patterns concerning PM CSEPs coincide with the contrasting modes of their host-adaption:the monocot PM fungi show a high-level of host specialization,likely reflecting an advanced host-pathogen arms-race,whereas the dicot PM fungi tend to practice polyphagy,which has presumably lessened the selective pressure for escalating an arms-race with a particular host.Strikingly,the tomato PM Oidium neolycopersici has a genome only half the size of other PM genomes,despite having a similar number of genes,suggesting that 0.neolycopersici has followed a unique genome evolutionary path.

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