Negative regulation of scavenger receptor SCARA5 in HMGB1-mediated inflammation
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- 英文论文题名：Negative regulation of scavenger receptor SCARA5 in HMGB1-mediated inflammation
- 论文作者：Guo Dong-yang ; Cao chao ; Shao tong ; Xiang Li-xin ; Shao Jian-zhong
- 英文论文作者：Guo Dong-yang ; Cao chao ; Shao tong ; Xiang Li-xin ; Shao Jian-zhong ; College of Life Sciences ; Zhejiang University ; Key Laboratory for Cell and Gene Engineering of Zhejiang Province ; Laboratory for Marine Biology and Biotechnology ; Qingdao National Laboratory for Marine Science and Technology
- 年：2016
- 作者机构：College of Life Sciences, Zhejiang University;Key Laboratory for Cell and Gene Engineering of Zhejiang Province;Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology;
- 英文论文关键词：SCARA5 ; HMGB1 ; Cp G-ODN ; recognition receptor ; inflammation ; negative regulation
- 会议召开时间：2016-11-04
- 会议录名称：第十一届全国免疫学学术大会分会场交流报告集
- 英文会议录名称：Proceedings of 2016 CSI Congress on Immunology
- 语种：英文
- 分类号：R392
- 学会代码：IGMD
- 会议名称：第十一届全国免疫学学术大会
- 会议地点：中国安徽合肥
- 主办单位：中国免疫学会
- 学会名称：中国免疫学会
- 页数：1
- 文件大小：254k
- 原文格式：D
- 会议级别：全国
摘要
<正>Scavenger receptor class A member 5(SCARA5)and high-mobility group box-1 protein(HMGB1)have become increasingly attractive for their critical functions in innate inflammatory reactions and disorders.However,the functional relevance between these two molecules has never been described.This study discovered that SCARA5 is a HMGB1-recognition receptor that is negatively involved in HMGB1-mediated inflammation in pufferfish(Tetraodon
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