2823例健康体检人群的疲劳情况及其与体检指标的相关性探讨
摘要
疲劳作为机体的一个主观感受症状,是机体体力或精力减弱或丧失的一种复杂的生理、心理及病理现象的体现。因此,疲劳既可以见于健康人,也可以作为一个症状,见于诸多躯体性和精神心理性疾病。20世纪80年代中期,通过研究发现,除了健康状态和疾病状态之外,人体还存在着一种介于健康和疾病之间的状态,即亚健康状态,特别是近年来随着竞争压力的加大及生活环境的多样性变化,处于亚健康状态的人群有逐年上升的趋势,而疲劳是亚健康状态的常见表现之一。总体来说,人体的整个生命过程就是健康、亚健康与疾病三种状态的相互转化,不论哪种状态都可能出现一定程度的疲劳。因此,疲劳是非常常见的一种现象或症状,对人们的日常生活有较大的影响,尤其是亚健康状态的疲劳。但不同人群的疲劳发生率到底有多高,其疲劳特点如何,目前我国尚缺乏系统的研究和相应的数据报道。
以整体观念和辨证论治为基本特点的中医学,对于疲劳的干预,尤其是机理尚不明确的亚健康状态的疲劳,具有较大的优势。因此,本研究拟通过对体检中心健康体检人群疲劳状态的调查,分析健康、亚健康及不同疾病人群中疲劳状态,探讨疲劳特点与常规体检指标之间的相关性,为进一步探讨疲劳的发生率、疲劳的类型特点及其可能的发生机理,以及未来的中医药干预研究提供依据。
研究一健康体检人群疲劳症状的发生率
目的：
通过对健康体检人群疲劳状态的调查,分析健康、亚健康及疾病人群的疲劳症状发生率。
方法：
通过现场调查的方法,运用国际上通用的疲劳量表(FS-14),对2011年3月至2012年3月间来北京小汤山医院体检中心体检并自愿接受调查的健康体检人群进行疲劳状况调查,并依本研究拟定疲劳症状判断标准(FS>3)、健康体检人群所属状态判定标准(见附录1)、流程及体检中心的体检报告,将体检人群分为健康、亚健康及疾病三大类,分析疲劳在各类人群中的发生情况；运用Epdata3.1软件建立数据库,录入所调查人群的疲劳及相关体检数据；运用SPSS17.0进行各种描述性分析。
结果：
1.健康体检人群的一般情况及健康状态分布
1.12823例健康体检人群的健康状态情况
符合调查人群纳入标准者共2823例,年龄范围为19～60岁,平均年龄为39.84±9.51岁；其中男性1398人(49.5%),平均年龄40.23±9.72岁,女性1425例(50.5%),平均年龄39.92±9.80岁。
2823例人群中,属于健康人群者204例(7.23%),其中标准健康人群13例(0.46%),准健康人群为191例(6.77%)；属于亚健康人群者1053例(37.30%),其中症状性亚健康人群为324例(11.48%),指标性亚健康人群为52例(1.84%),症状-指标性亚健康人群为677例(23.98%)；属于疾病人群者1566例(55.47%),其中出现频率排在前十位者为高血压、慢性咽炎、脂肪肝(中度以上)、乳腺增生(中度以上)、高血脂、子宫肌瘤、糖尿病、过敏性鼻炎、甲状腺结节、颈椎病。
2.不同健康状态体检人群的疲劳发生率
2.1健康人群的疲劳发生情况
204例健康人群(包括标准健康和准健康人群)中,有167例存在有疲劳的情况,其疲劳发生率为81.86%
2.2亚健康人群的疲劳发生情况
1053例亚健康人群(包括症状性亚健康、指标性亚健康、症状-指标性亚健康)中,有881例存在有疲劳的情况,其疲劳发生率为83.67%；其中症状亚健康疲劳发生率为89.50%,症状-指标性亚健康疲劳发生率为87.30%。
2.3疾病人群的疲劳发生情况
1566例疾病人群中(包括患有不同疾病的所有人群)中,有1448例存在有疲劳的情况,其疲劳发生率为92.46%。
排在前10位的疾病患者出现疲劳的例数及发生率依次为,高血压480例(93.00%)、脂肪肝277例(92.00%)、慢性咽炎272例(89.77%)、高血脂262例(92.58%)、乳腺增生353例(92.88%)、子宫肌瘤150例(88.34%)、糖尿病148例(91.92%)、过敏性鼻炎100例(90.91%)、甲状腺结节89例(89.90%)、颈椎病75例(96.15%),其中以有颈椎病的患者的疲劳发生率为最高,各疾病之间的疲劳发生率无统计学差异。
结论：
根据本研究所采用的研究方法初步得出：不同健康状态的体检人群,均有疲劳症状的发生,其发生率由高到低依次为疾病、亚健康及健康人群,反映了疲劳发生的广泛性。
研究二不同健康体检人群的疲劳特点研究
目的：
评价健康、亚健康、疾病三类人群的疲劳类型、程度及特征方法：
通过现场调查的方法,运用国际上通用的疲劳量表(FS-14)及课题组自行研制的疲劳自评量表(FSAS),对2011年3月至2012年3月间来北京小汤山医院体检中心体检,并自愿接受调查的健康体检人群进行疲劳状况的调查;依据本研究拟定的健康体检人群所属状态判定标准(见附录1),将体检人群分为健康、亚健康及疾病三大类,分析、比较各类人群的疲劳发生类型、程度及特点；运用Epdata3.1软件建立数据库,录入所调查人群的疲劳及相关体检数据；运用SPSS17.0进行各种分析。
结果：
本研究所分析的对象是从“研究一”的体检人群中选取的具有疲劳(FS总分≥3分)的2496例人群,其中男性1284例(51.44%),平均年龄为40.40±9.70,女性1212例(48.56%),平均年龄为39.67±9.46；属于健康状态者167例(6.69%)全部为准健康者)属于亚健康状态者881例(35.30%),其中症状性亚健康者为290例(11.62%),症状-指标性亚健康人群为591例(23.68%)；属于疾病人群者1448例(58.01%)
1基于疲劳量表(FS-14)疲劳特点的研究
健康、亚健康、疾病三组人群的疲劳总分、躯体疲劳分值及精神疲劳分值分别为4.86±1.96、2.57±1.65、2.28±1.39；5.88±3.13、3.53±2.25、2.35±1.71；5.52±2.78、3.35±2.11、2.17±1.59。其中以疾病人群的躯体疲劳分值及疲劳总分为最高,三者之间的比较
1.1健康人群(准健康人群)的疲劳特点
167例准健康人群中,男、女两性的躯体、脑力及及总体疲劳分值分别为2.60±1.63VS2.55±1.68、2.23±1.46VS2.34±1.30、4.83±1.94VS4.89±1.99,女性高于男性,但无统计学差异；从不同年龄段的疲劳分值看,以41-50岁年龄段者躯体、脑力及总体疲劳的分值为最高,以51-60岁年龄段的躯体及总体疲劳分值为最低,以31-40年龄段者的岁脑力疲劳分值为最低,不同年龄段的比较无统计学差异(P>0.05)；从疲劳量表的条目分布看,脑力疲劳中以“你感觉到记忆力下降了吗?”出现的频率为最高(60.37%),躯体疲劳中以“你觉得需要多休息吗?”出现的频率为最高(47.56%)。
1.2亚健康人群的疲劳特点
881例亚健康人群中(包括症状亚健康和症状-指标亚健康人群),躯体疲劳和总体疲劳的分值以41-50岁年龄段为最高,以51-60岁年龄段为最低；脑力疲劳的分值以21-30岁年龄段为最高,41-50岁年龄段为最低；从量表的条目分布来看,在症状性亚健康人群中,以“你觉得需要多休息吗?”出现的频率为最高(73.10%)；在症状-指标性亚健康人群中以“你有被疲劳困扰的情况吗?”出现的频率为最高(53.64%)
症状亚健康人群的躯体、脑力及总体疲劳的分值均高于症状-指标性亚健康人群,疲劳分值分别为4.37±2.14VS3.14±2.14、2.60±1.86VS2.20±1.61、6.94±3.22VS5.34±2.88,并且有统计学差异(P<0.05)
1.3疾病人群的疲劳特点
1448例疾病人群中,男、女两性的躯体及总体疲劳的分值分别为3.31±2.10VS3.39±2.12、5.49±2.81VS5.55±2.76,女性均高于男性,但无统计学差异;躯体疲劳和总体疲劳的分值以31～40岁年龄段为最高,以51～60岁年龄段为最低；脑力疲劳的分值以21～30岁年龄段为最高,以41～50岁年龄段为最低；从量表条目的分布来看,以“你觉得需要多休息吗?”出现的频率为最高57.2%。
1.4常见疾病的疲劳特点
出现频率排在前10位的疾病中,根据其疲劳分值由高到低的顺序依次如下：①躯体疲劳：颈椎病(3.79±2.43)、高血脂(3.45±2.16)、甲状腺结节(3.43±1.88)、乳腺增生(3.41±2.17)、糖尿病(3.39±2.25)、过敏性鼻炎(3.38±2.11)、高血压(3.30±2.07)、子宫肌瘤(3.27±2.04)、脂肪肝(3.23±2.11)、慢性咽炎(3.21±2.12)。②精神疲劳：糖尿病(2.31±1.67)、颈椎病(2.31±1.75)、慢性咽炎(2.28±1.62)乳腺增生(2.23±1.70)、过敏性鼻炎(2.19±1.67)、子宫肌瘤(2.18±1.66)、高血压(2.14±1.56)、甲状腺结节(2.13±1.72)、高血脂(2.11±1.57)、脂肪肝(2.11±1.53)。③总体疲劳：颈椎病(6.09±3.22)、糖尿病(5.70±3.20)、乳腺增生(5.64±2.81)高血脂(5.56±2.81)、甲状腺结节(5.56±2.85)、过敏性鼻炎(5.55±3.02)、慢性咽炎(5.49±2.83)、子宫肌瘤(5.47±2.80)、高血压(5.44±2.76)、脂肪肝(5.33±2.70)。
具体条目的分布,高血压、脂肪肝、慢性咽炎、高血脂、糖尿病、过敏性鼻炎、甲状腺结节、颈椎病患者均以“你觉得需要多休息吗?”出现的频率为最高,精神疲劳类型均以“你感觉到记忆力下降了吗?”出现的频率为最高。
对高血压、糖尿病、脂肪肝的进一步分析比较发现：①体检时血压异常的高血压患者的3个疲劳分值均高于血压正常的高血压患者；②体检时血糖水平异常的糖尿病患者3个疲劳分值均高于血糖水平正常的糖尿病患者,其中躯体疲劳分值在两者间具有统计学差异(P<0.05)；③重度脂肪肝患者的脑力及总体疲劳分值均高于中度脂肪肝患者；④高血压合并糖尿病及高血脂患者的躯体、脑力及总体疲劳的分值均高于单纯的高血压患者,其中脑力疲劳在两组间有统计学差异；⑤比较单纯出现高血压、高血脂及糖尿病三组人群的疲劳分值,躯体疲劳分值以高血脂患者为最高,脑力疲劳及总体疲劳分值以糖尿病患者为最高。
2基于疲劳自评量表(FSAS)疲劳特点的研究
健康(准健康)、亚健康、疾病三组人群的“躯体疲劳”因子的分值分别为27.67±22.21、30.81±23.31、33.86±23.62；“疲劳对睡眠休息的反应”因子分值分别29.79±27.21、26.08±26.35、28.51±27.13,两个因子的分值在三组人群中均有统计学差异(P<0.05)。
2.1健康人群(准健康人群)疲劳特点
两性疲劳特点分值女性躯体疲劳高于男性,精神疲劳、疲劳后果、疲劳程度总分、疲劳对睡眠休息的反应、疲劳的情境性5个因子分值男性均高于女性。(1)疲劳的类型及程度
167例中,准健康人群疲劳类型分值一样,疲劳程度以轻度为主,躯体疲劳为56.71%,精神疲劳程为64.02%,疲劳后果为63.41%。(2)疲劳的特征
准健康人群在休息/睡眠无法缓解疲劳的反应中,有29.07%的人经过休息或者睡眠后,疲劳可以得到缓解；疲劳情境性中,仅有0.37%的人不明显。
2.2亚健康人群疲劳特点
881例亚健康人群中,男、女两性以躯体疲劳为主要类型,分值为30.47±23.26、31.16±23.38女性高于男性,但无统计学差异；不同年龄段之间,31～40岁的躯体疲劳、精神疲劳、疲劳后果分值最高,41-50岁的精神疲劳、疲劳程度分值最高,51～60岁的疲劳的情境性分值最高,不同年龄段之间得分无统计学差异(P>0.05)
(1)疲劳的类型及程度
症状性亚健康及症状-指标亚健康疲劳类型均属于躯体疲劳类型,分值为31.37±23.87、30.36±23.74,并且有统计学差异,症状性亚健康躯体疲劳最明显。
(2)疲劳的特征
症状-指标性亚健康在休息/睡眠无法缓解疲劳的反应中高于症状亚健康,有36.58%的人认为明显；仅有31.09%的人能够缓解疲劳症状的表现；在疲劳情境性分析发现,程度以比较明显为主,其中症状亚健康为40.85%高于症状-指标亚健康40.64%。
2.3疾病人群疲劳特点
1448例疾病人群中,男、女两性以躯体疲劳为主要类型,分值为33.64±32.19、33.67±32.25；女性高于男性,但无统计学差异；不同年龄段之间,31-50岁之间疲劳类型、程度及特征分值最高,得分无统计学差异(P>0.05)
(1)疲劳的类型及程度
疾病人群属于躯体疲劳,分值为33.86±23.62,程度以中度为主,躯体疲劳中度占61.17%,精神疲劳中度占68.42%,疲劳后果中度占68.79%,总体疲劳中度占71.15%
(2)疲劳的特征
疾病人群中仅有29.07%的人认为,休息／睡眠可以缓解疲劳症状；疲劳情境性仅有0.37%的人认为不明显
2.4常见疾病人群的疲劳特点
本次调查出现最为长见的10种疾病分别为高血压、乳腺增生、脂肪肝、慢性咽炎、高血脂、子宫肌瘤、糖尿病、过敏性鼻炎、甲状腺结节、颈椎病。
①躯体疲劳分值由高至低为,颈椎病>甲状腺结节>过敏性鼻炎>慢性咽炎>高血脂>高血压>乳腺增生>脂肪肝>子宫肌瘤>糖尿病
②精神疲劳分值,由高至低为,高血脂>过敏性鼻炎>乳腺增生>甲状腺结节>脂肪肝>颈椎病>高血压>慢性咽炎>糖尿病>子宫肌瘤
③休息/睡眠反应由高至低为,颈椎病>脂肪肝>糖尿病>高血脂>慢性咽炎>高血压>甲状腺结节>过敏性鼻炎>子宫肌瘤>乳腺增生
④疲劳情境性由高至低为,颈椎病>高血脂>慢性咽炎>糖尿病>高血压>脂肪肝>敏性鼻炎>乳腺增生>子宫肌瘤>甲状腺结节
⑤高血压血压异常患者,疲劳后果及疲劳程度总分均高于血压正常者,两者具有统计学差异(P<0.05)；糖尿病血糖异常患者,在疲劳情境性的分值为56.92±25.11,高于正常者,具有统计学差异(P<0.05)。
结论：
1基于疲劳量表(FS-14)的疲劳特点研究
1.1健康(准健康)人群疲劳特点：41-50岁年龄段的人容易出现疲劳困扰、需要多休息、记忆力下降等的表现,而年龄越大躯体及总体疲劳会有所下降。
1.2亚健康人群疲劳特点：男性躯体疲劳要比女性明显,容易出现需要多休息并且被疲劳困扰的不适表现,尤其是症状性亚健康人群会比症状-指标性亚健康人群容易出现不适症状表现,导致疲劳感加重。
1.3疾病人群疲劳特点：女性比男性的疲劳特点更为明显,尤其在31-40岁的时候,容易出现需要多休息的躯体疲劳表现。
1.4常见疾病疲劳特点：颈椎病及体检时高血压、糖尿病患者血压、血糖异常时出现疲劳困扰、需要多休息、精力不够、肌肉力量减小等躯体疲劳表现最明显,当高血压患者合并糖尿病及高血脂多种疾病时,疲劳症状均会加重,而单纯高血压、高血脂、糖尿病三种疾病又以高血脂疲劳症状更为明显；重度脂肪肝患者,出现注意力不集中、头脑不清晰、记忆力下降等,脑力疲劳的表现明显。
2基于疲劳自评量表(FSAS)疲劳特点的研究
2.1健康、亚健康、疾病人群的疲劳自评量表各因子分值的比较
健康体检人群的疲劳量表(FSAS)疲劳特点显示,①躯体疲劳分值由高至低分别为疾病>亚健康>准健康,说明四肢酸软疲乏无力、体力不支、自觉身体虚弱的表现疾病人群最明显,其次是亚健康及准健康。②疲劳对睡眠休息的反应分值由高至低依次为疾病>健康>亚健康,所以疾病人群由于有自身疾病存在,而导致疲劳症状的出现无法通过休息／睡眠得到缓解,由此可知疲劳症状与休息／睡眠无关,而是与疾病本身有关。
2.2三组人群疲劳自评量表的疲劳特点
2.2.1准健康人群疲劳类型、程度及特征
准健康人群以躯体疲劳为主,程度均为轻度,容易出现四肢酸软、疲乏无力、头脑反应迟钝、情绪低落、对事情感到厌烦不想再做下去、学习效率减低等的表现的表现；并且在情绪低落、嘈杂及闷热环境、精神紧张或负面情绪等的影响而容易使疲劳症状加重。
2.2.2亚健康人群疲劳类型、程度及特征
症状性亚健康组比症状-指标亚健康组容易出现,四肢酸软、疲乏无力、身体虚弱的感觉明显、注意力不集中、健忘、反应迟缓等现象；导致出现情绪低落、对事情感到厌烦不想再做下去、学习效率减低等的疲劳后果表现；而症状-指标性亚健康组认为休息或者睡眠后,疲劳无法缓解明显；因为情绪低落、嘈杂及闷热环境、精神紧张等,外环境的变化及负面情绪容易加重症状。
2.2.3疾病人群疲劳类型、程度及特征
疾病人群以躯体疲劳为主,有一半时间会出现四肢酸软疲乏无力、四肢肌肉无力的表现,并且导致学习效率降低的疲劳后果表现；疾病人群疲劳具有明显的情境特异性,由于疾病造成躯体及精神的压力影响,所以大部分人认为从事愉快的事情可以减轻疲劳症状,并且有一半人认为情绪低落或急躁时感到疲劳加重。
2.2.4常见疾病疲劳类型、程度及特征
颈椎病患者容易出现四肢酸软、疲乏无力、四肢肌肉无力,经过休息/睡眠後仍然无法缓解疲劳症状,并且情绪低落或急躁时感到疲劳加重；高血脂患者容易出现忘事、头脑反应迟钝、学习效率降低。
高血压患者血压水平异常时,可能会加重情绪低落、对事情感到厌烦不想再做下去、学习效率减低等的表现；糖尿病患者血糖水平异常时,可能更容易因为情绪低落、嘈杂及闷热环境、精神紧张等,外环境的变化及负面情绪更加敏感导致疲劳感加重；当高血压合并了糖尿病及高血脂时,出现休息／睡眠无法缓解疲劳症状,并且在情绪低落、嘈杂及闷热环境、精神紧张等,外环境的变化及负面情绪的影响造成疲劳症状进一步的加重。
研究三不同健康体检人群疲劳发生及症状特点与四季相关性分析
目的：
探讨不同健康体检人群在不同季节的疲劳症状发生率及疲劳的类型、程度和特点。
方法：
依据《二十四节气解》,以一年中四季开始的节气“四立”(立春、立夏、立秋、立冬)作为四季的划分标准(3.21-6.21为春季,6.22-9.22为夏季,9.23-12.21为秋季,12.22-3.20为冬季),对北京小汤山健康体检中心调查的2823例健康体检人群划归于四季,分析比较在不同季节的调查人群疲劳发生率及特点的差异,探讨疲劳与季节的关系；运用SPSS17.0进行各种描述性分析。
结果：
1四季中2823例健康体检人群的一般情况
年龄范围为19～60岁,春季平均年龄40.61±9.55岁,共770例,其中男性406人(29.04%)女性364人(25.54%)；夏季平均年龄38.19±8.90岁,共575例,其中男性296人(21.17%)、女性279人(19.58%)；秋季平均年龄40.04±9.739岁,共1185例,其中男性553人(39.56%)、女性632人(44.35%)；冬季平均年龄40.20±9.28岁,共293例,其中男性143人(10.23%)女性150入(10.53%)春季年龄最大,夏季年龄最小。
2健康体检人群的疲劳发生在四季中的分布
2.1不同健康状态在四季疲劳的发生情况
健康人群在冬季疲劳发生情况最高为90.91%,亚健康人群在夏季疲劳发生情况最高为89.57%,疾病人群冬季最高占92.99%,其中亚健康、疾病人群两组组均为春季疲劳发生情况最低,两组在不同季节中疲劳发生情况存在统计学差异(P<0.05)。
2.2四季中疲劳量表FS-14的疲劳特点情况
2.2.1三组人群的疲劳特点
①健康人群躯体疲劳分值均高于脑力疲劳,在秋季分值最高。②亚健康人群躯体、脑力及总体疲劳均存在统计学差异(P<0.05)。③疾病人群在不同季节中躯体疲劳在夏季最高、脑力疲劳及总体疲劳秋季最高,四季躯体疲劳高于脑力疲劳,疲劳特点均存在统计学差异(P<0.05)。
2.2.2常见疾病人群的不同季节疲劳特点
①高血压患者在不同季节疲劳分值发现,躯体疲劳在春季时最高冬季最低,脑力疲劳冬季最高春季最低,并且存在统计学差异(P<0.05)。②乳腺增生、高血脂、糖尿病、颈椎病患者在不同季节疲劳分值发现,躯体疲劳在夏季时最高冬季最低,并且存在统计学差异(P<0.05)③过敏性鼻炎患者在不同季节疲劳分值发现,脑力疲劳在秋季时最高,并且存在统计学差异(P<0.05)。
2.3基于疲劳自评量表(FSAS)的不同季节疲劳特点情况
2.3.1各组人群在四季中疲劳类型及程度：①躯体疲劳：健康及亚健康人群躯体疲劳因子分值在秋季最高；健康人群夏季分值最低,亚健康人群冬季分值最低；两组人群四季中劳类型存在统计学差异(P<0.05)；躯体疲劳程度比较发现,健康及亚健康躯体疲劳为轻度在秋季时最高,疾病人群躯体疲劳为中度在秋季时最高,三组人群存在统计学差异(P<0.05)。②精神疲劳：健康、亚健康人群精神疲劳因子分值有统计学意义(P<0.05),均为秋季最高,两组人群精神疲劳程度以轻度为主。③疲劳后果：健康、亚健康人群疲劳后果因子分值有统计学意义(P<0晒.05),均为秋季最高,在疲劳后果程度中以轻度为主,而疾病与亚健康人群有统计学意义(P<0.05)④疲劳程度总分：健康、亚健康人群疲劳程度总分因子分值有统计学意义(P<0.05),均为秋季最高,在疲劳程度中健康及亚健康人群以轻度为主,疾病人群以中度为主。
2.3.2各组人群在四季中的疲劳特征：①疲劳对休息/睡眠的反应：健康、亚健康人群疲劳对休息/睡眠的反应因子分值有统计学意义(P<0.05),均为秋季最高。②疲劳情境性：健康、疾病、亚健康人群疲劳情境性的因子分值有统计学意义(P<0.05),健康人群在冬季最高,疾病、亚健康人群在秋季最高。
2.3.3常见疾病的疲劳症状在四季发生情况：①高血压患者在不同季节疲劳分值发现,疲劳类型属于躯体疲劳,在秋季时最高,疲劳后果、疲劳对睡眠休息的反应、疲劳的情境性有统计学差异(P<0.05)。②慢性咽炎患者在不同季节疲劳分值发现,疲劳类型属于躯体疲劳,在秋季时最高,躯体疲劳、精神疲劳、疲劳后果、疲劳程度总分、疲劳对睡眠休息的反应有统计学差异(P<0.05)。③乳腺增生患者在不同季节疲劳分值发现,春秋两季躯体疲劳明显,夏冬两季精神疲劳明显,疲劳的情境性有统计学差异(P<0.05)。④高血脂患者在不同季节疲劳分值发现,仅疲劳的情境无统计学差异(P>0.05)。⑤糖尿病患者在不同季节疲劳分值发现,疲劳类型以精神疲劳为主,疲劳后果、疲劳程度总分有统计学差异(P<0.05)。⑥过敏性鼻炎患者在不同季节疲劳分值发现,春冬两季以躯体疲劳为主,夏秋两季以精神疲劳为主,疲劳的情境性有统计学差异(P<0.05)
结论：
1健康体检人群的疲劳发生在四季中的分布
亚健康人群在夏季时好发疲劳症状最为明显,疾病人群在冬季时疲劳症状最为明显；女性春夏两季疲劳症状最为明显,在41-60岁年龄段的人在春季时疲劳症状最为突出到秋季时疲劳症状会有所缓解。
2四季中疲劳量表FS-14的疲劳特点情况
2.1三组人群的疲劳特点：①健康人群出现疲劳困扰、需要多休息感到力不从心、精力不够及总体疲劳随着季节变化逐渐增高,在冬季会有所缓解。②亚健康人群疲劳症状会随着季节而缓解,在秋季时疲劳症状最轻,其中症状亚健康人群在夏季出现疲劳困扰、需要多休息感到力不从心、精力不够等躯体、疲劳总体疲劳的表现均比症状-亚健康人群要明显。③疾病人群在夏季时出现疲劳困扰、需要多休息感到力不从心、精力不够等躯体疲劳表现最明显；在秋季时注意力无法集中、头脑不清晰、记忆力下降等总体疲劳最明显。
2.2常见疾病人群的不同季节疲劳特点：①高血压患者出现疲劳困扰、需要多休息感到力不从心、精力不够等表现,在春季时最为明显；而在冬季时感到注意力困难、记忆力下降,对习惯做的事情失去兴趣等表现最为明显。②乳腺增生、高血脂、糖尿病、颈椎病患者容易在夏季时出现疲劳困扰、需要多休息感到力不从心、精力不够等表现③过敏性鼻炎患者容易在秋季出现注意力困难、头脑不清晰、记忆力下降、对习惯做的事情失去兴趣等表现最为明显。
3基于疲劳自评量表(FSAS)的不同季节疲劳特点情况
3.1各组人群在四季中疲劳类型及程度：①躯体疲劳：三组人群在秋季时四肢酸软乏力、体力不支、身体虚弱等表现程度最重,在冬季时疲劳症状最轻。②精神疲劳：健康、亚健康人群出现注意力不集中、反应迟钝、忘事等症状,在夏季至秋季精神疲劳有增高趋势,秋季至冬季精神疲劳有下降趋势,而疾病人群从夏季至冬季时有增长的趋势。③疲劳后果：健康及亚健康人群在夏季至秋季,出现情绪低落、对事情感到厌烦不想再做下去、学习效率减低等的表现有增高趋势,秋季至冬季疲劳后果有下降趋势,疾病人群从春季至夏季出现下降趋势,而从夏季至冬季出现增长的趋势。④疲劳程度总分：健康及亚健康人群在夏季至秋季疲劳程度逐渐加重,秋季至冬季疲劳程度逐渐减轻,而疾病人群只有在夏季时疲劳程度最轻。
3.2各组人群在四季中的疲劳特征：①疲劳对休息/睡眠的反应：健康及亚健康人群在夏季时,睡眠或休息后对疲劳缓解程度缓解不明显,而疾病人群可能是因为自身疾病原因,一年四季中睡眠或休息后对疲劳缓解程度趋势并不明显。②疲劳情境性：健康人群在冬季时对嘈杂的环境、紧张情绪、从事愉快的事情疲劳症状可以缓解等表现最为明显,从夏季至冬季有逐渐增加的趋势；而疾病及亚健康人群均在秋季时,因为不同环境或情绪导致疲劳症状加重的表现最明显。
3.3常见疾病的疲劳症状在四季发生情况：①高血压患者在秋季时出现情绪低落、对事情感到厌烦不想再做下去、学习效率减低、经过睡眠或休息后对疲劳缓解程度缓解不明显,并且容易因为周边环境及负面情绪加重疲劳症状；②慢性咽炎患者在秋季时,出现四肢无力、注意力不集中、健忘、反应迟缓、睡眠或休息后对疲劳缓解程度缓解不明显等现象最为明显。③乳腺增生患者在春秋两季感觉躯体疲乏无力较为明显。在夏冬两季注意力不集中、健忘、反应迟缓等现象表现比较明显,并且对于嘈杂闷热环境、紧张情绪等负面情绪加重疲劳症状更为明显。④高血脂患者在春、夏、秋季节容易出现注意力不集中、健忘、反应迟缓等精神疲劳现象表现比较明显,在冬季时容易出现疲乏无力等的躯体疲劳表现明显,在秋季时容易出现情绪低落、对事情感到厌烦不想再做下去、学习效率减低、睡眠或休息后对疲劳缓解程度无法缓解等的表现明显。⑤糖尿病患者容易出现注意力不集中、健忘、反应迟缓等精神疲劳现象表现比较明显,在秋季时容易出现情绪低落、对事情感到厌烦不想再做下去、学习效率减低等的表现明显。⑥过敏性鼻炎患者在秋季时对于嘈杂闷热环境、紧张情绪等负面情绪加重疲劳症状更为明显。
研究四不同健康体检人群疲劳状态与体检指标相关性的探索
目的：
探讨健康、亚健康、疾病三类健康体检人群的疲劳状态与体检指标间的相关性方法：
根据疲劳量表(FS-14)测评结果,疲劳总分值≥3且具有疲劳症状的体检人群,采用疲劳自评量表(FSAS)对2496例不同健康体检人群的疲劳类型、程度和特征分值与体检指标进行相关分析,探讨疲劳与理化指标之间的相关性；运用SPSS17.0对数据进行回归分析。
结果：
12496例健康体检人群疲劳类型及特征与体检指标回归分析
1.1疲劳类型、程度：经回归分析发现,躯体疲劳、精神疲劳、疲劳后果、疲劳程度因子分值与部分体检指标关系密切,其中①躯体疲劳反应出“淋巴细胞”,回归系数为0.144呈现正相关。②精神疲劳反应出“红细胞平均血红蛋白浓度”,回归系数为-0.072和-0.064,两者回归系数为呈现负相关。③疲劳后果反应出“血小板压积”,回归系数为14.51,并且呈现正相关。④疲劳程度反应出“血小板压积”,回归系数为14.559,并且呈现正相关。
1.2疲劳特征：经回归分析发现,①疲劳对睡眠休息的反应因子分值与“谷丙酶”体检指标关系密切,回归系数为0.114呈现正相关。②疲劳的情境性与“红细胞平均血红蛋白量、血小板计数和谷丙酶”体检指标关系密切,其中红细胞平均血红蛋白量回归系数为-0.529为负相关,血小板计数、谷丙酶回归系数为0.024及0.091呈正相关。
2不同健康状态的疲劳特点与体检指标回归分析
2.1准健康人群疲劳类型、程度及特征与体检指标回归分析
2.1.1疲劳类型、程度：准健康人群①躯体疲劳与“低压、体重和总胆固醇”体检指标关系密切,其中体重回归系数为-0.642呈负相关,低压、总胆固醇回归系数为1.102和5.246呈正相关。②疲劳后果与“血糖”体检指标关系密切,回归系数为6.28呈正相关。③疲劳程度与“嗜酸性粒细胞百分比”体检指标关系密切,回归系数为2.423呈正相关。
2.1.2疲劳特征：经回归分析发现,准健康人群①疲劳对睡眠休息的反应与“嗜碱性粒细胞数量”体检指标关系密切,回归系数为39.177呈正相关。②疲劳的情境性与“红细胞体积分布宽度”体检指标关系密切,回归系数为-10.781呈负相关。
2.2症状亚健康人群疲劳类型、程度及特征与体检指标回归分析
症状亚健康人群在躯体疲劳、精神疲劳、疲劳程度分值筛选出与体检指标关系密切的指标,其中①躯体疲劳与“红细胞平均血红蛋白浓度”体检指标关系密切,回归系数为-0.38呈负相关。②精神疲劳与“血小板体积分布宽度和红细胞平均血红蛋白浓度”体检指标关系密切,回归系数为-0.245及-0.242两者均呈负相关。③疲劳程度与“血小板体积分布宽度”,回归系数为-1.214呈负相关；而疲劳后果、疲劳对睡眠休息的反应、疲劳的情境性未筛检到关系密切的体检指标。
2.3症状-指标亚健康人群疲劳类型、程度及特征与体检指标回归分析
症状-指标亚健康人群在精神疲劳、疲劳后果、劳疲劳程度总分、疲劳的情境性分值筛选出与体检指标关系密切的指标,其中①精神疲劳与“尿素氮”体检指标关系密切,回归系数为0.438呈正相关。②疲劳后果与“总胆固醇”体检指标关系密切,回归系数为-2.132呈负相关。③疲劳程度与“总胆固醇”,回归系数为-2.259并且现负相关。④疲劳的情境性与“谷丙酶和血小板计数”体检指标关系密切,回归系数为0.176及0.0398呈正相关。
2.4疾病人群疲劳类型、程度及特征与体检指标回归分析
2.5.1疲劳类型、程度：经回归分析发现,疾病人群①躯体疲劳与“血压”体检指标关系密切,其中高压呈现负相关,低压呈现正相关。②精神疲劳与“低压、血红蛋白和红细胞体积分布宽度”体检指标关系密切,其中血红蛋白回归系数为-0.081呈负相关,低压及红细胞体积分布宽度回归系数为0.139和0.085呈现正相关。③疲劳程度总分与“低压”体检指标关系密切,回归系数为0.098呈正相关。
2.5.2疲劳特征：经回归分析发现,疾病人群①疲劳对睡眠休息的反应与“谷丙酶”体检指标关系密切,回归系数为0.057呈正相关。②疲劳的情境性与“pH值和红细胞平均血红蛋白量”体检指标关系密切,回归系数为-2.341及-0.273呈负相关。结论：
12496例健康体检人群疲劳类型及特征与体检指标回归分析
本次调研的健康体检人群淋巴细胞、血小板压积、谷丙酶、血小板计数呈正相关,体检指标越高可能导致躯体疲劳、劳后果表现、疲劳程度、疲劳对睡眠休息的反应、疲劳的情境性分值增高,出现四肢酸软、疲乏无力、身体虚弱、头脑反应迟钝、学习效率减低、休息/睡眠无法缓解疲劳,情绪低落、嘈杂及闷热环境、精神紧张加重疲劳感的表现越明显；而当红细胞平均血红蛋白浓度指标、红细胞压积呈负相关,可能说明指标越高或许可以缓解忘事、头脑反应迟钝、注意力不能集中、思路不清晰的精神疲劳表现及缓解由于情绪低落、嘈杂及闷热环境、精神紧张等,外环境变化及负面情绪导致疲劳感加重的疲劳情境性表现。
2不同健康状态的疲劳特点与体检指标回归分析
2.1准健康人群
准健康人群的总胆固醇、血糖、嗜酸性粒细胞百分比、嗜碱性粒细胞数量、体检指标越高可能导致躯体疲劳、疲劳后果、疲劳程度、疲劳对睡眠休息的反应分值越高,表现出四肢酸软、疲乏无力、身体虚弱、头脑反应迟钝、学习效率减低、休息/睡眠无法缓解疲劳等,出现疲劳感加重的表现越明显；而当体重、红细胞体积分布宽度指标越低,躯体疲劳及疲劳情境性的疲劳表现越轻,
2.2症状亚健康人群
症状亚健康人群的红细胞平均血红蛋白浓度、血小板体积分布宽度和红细胞平均血红蛋白浓度体检指标越低,可能导致躯体疲劳、精神疲劳、疲劳程度分值越高,表现出四肢酸软、疲乏无力、身体虚弱、注意力不能集中、思路不清晰、等出现疲劳感加重的表现越明显。
2.3症状-指标亚健康人群
症状-指标亚健康人群的尿素氮、谷丙酶、血小板计数体检指标越高,可能导致精神疲劳、疲劳的情境性分值越高,表现出注意力不能集中、思路不清晰、在情绪低落、嘈杂及闷热环境、精神紧张、外环境的变化及负面情绪等,疲劳感加重表现越明显；而当总胆固醇体检指标越低,疲劳后果、疲劳程度的疲劳表现越不明显。
2.4疾病人群
疾病人群的血压、红细胞体积分布宽度、谷丙酶体检指标越高,可能导致躯体疲劳、精神疲劳、疲劳程度、疲劳对睡眠休息的反应分值越高,表现出四肢酸软、疲乏无力、身体虚弱、注意力不能集中、思路不清晰、休息／睡眠无法缓解疲劳等出现疲劳感加重的表现越明显；而当血红蛋白、pH值和红细胞平均血红蛋白量指标越高精神疲劳、疲劳的情境性疲劳表现越轻。
As a symptom of subjective feeling, fatigue is complex reflect of physiological, psychological and pathological phenomena of weaken or loss of physical or mental energy. Therefore, fatigue can be found in healthy people. And also can be used as a symptom in many physical and mental diseases. The study found that there still exist a sub-health state between health and disease in addition to health and disease in the mid1980s. In recent years, with the competition pressure increasing and the diversity of living environment changing, the people in the state of sub-health have the trend of increasing year by year. Fatigue is the common performance of the sub-health status. In general, the whole life process of the human body is mutual transformation of health, sub-health and disease three states. No matter what kind of state may appear a certain degree of fatigue. Therefore, fatigue is the very common phenomenon or symptom. It has larger influence on people's daily life, especially the fatigue of sub-health state. But at present our country still lack of systematic research and the corresponding data reports about fatigue incidence and fatigue characteristics of different people.
The basic characteristics of traditional Chinese medicine are the overall concept and differentiation and treatment. There are many advantages in TCM intervention of fatigue, especially for which mechanism is not clear. Therefore, the investigation of sub-fatigue in the crowd of medical examinations from medical center were carried out. The fatigue status of the crowd of health,sub-health and different disease were analyzed.The relationship between medical examination indexes and the fatigue characteristics were discussed. This study may provide the basis for further study about incidence, characteristics of fatigue type,possible occurrence mechanism and traditional Chinese medicine intervention study of fatigue.
Research one:the incidence of fatigue symptoms among the crowd of healthy medical examinations.
Objective:
Through the investigation of fatigue state in the crowd of healthy medical examinations, the incidence of the fatigue symptom in the crowd of health, sub-health and the disease were analyzed.
Methods:
Through the method of field investigation, common international fatigue scale (FS-14) was applied. The investigation of fatigue in the crowd of medical examination were carried out in Beijing xiaotangshan hospital medical center from March2011to March2012. The crowd were divided into three groups of health, sub-health and illness in accordance with fatigue symptom judgment standard (FS or3) this research protocol, criteria of subordinate state in the health check-up crowd, process and medical report from physical examination center. The occurrence of fatigue in all kinds of the crowd were analyzed. The database was established by using Epdata3.1software. The related physical examination data was input. All kinds of descriptive analysis were done by using SPSS17.0.
Results:
1General healthy people and healthy state distribution
1.12823cases of healthy people healthy state.
Meet the surveyed population inclusion criteria, a total of2823cases, Age range19to60years old, with an average age of39.84±9.51years; males and1398(49.5%), the average age of40.23±9.72years old, women,1425cases (50.5%), with an average age of39.92±9.80years.
2823cases of population, belong to the healthy population,204cases (7.23%), Standard healthy population of13patients (0.46%), the quasi-healthy population of191cases (6.77%); Is a sub-health population in1053cases (37.30%), symptomatic sub-health population,324cases (11.48%), indicative of sub-health population of the52cases (1.84%), symptoms-indicators the sexual subhealth crowd of677cases (23.98%); belongs disease crowd of1,566cases (55.47%), which appear frequency among the top ten by high blood pressure, chronic pharyngitis, fatty liver (more moderate), hyperplasia (more moderate), Hypertension, chronic pharyngitis, fatty liver (more moderate), hyperplasia (more moderate), high cholesterol, uterine fibroids, diabetes, allergic rhinitis, thyroid nodules, cervical spondylosis.
2. Fatigue incidence of different health status examination crowd
2.1Healthy population of fatigue
204healthy people (including the standard of health and prospective health crowd),167cases of fatigue and fatigue incidence of81.86%.
2.2Fatigue occurrence of sub-health population
1053cases of sub-health population(Include Symptomatic sub-health、indicator sub-health, symptoms-indicators sub-health),881cases exist fatigue, Fatigue incidence of83.67%;The symptoms of sub-health fatigue incidence89.50%, the symptoms-indicative sub-health fatigue incidence of87.30%.
2.3The disease populations fatigue happens
1566cases of disease groups (including all populations of suffering from various diseases),1448cases exist where fatigue, fatigue incidence92.46%.
The number of cases and the incidence of the top10diseases in patients with fatigue order, Hypertension in480cases (93.00%), fatty liver,277cases (92.00%), the chronic pharyngitis 272cases (89.77%), high cholesterol,262cases (92.58%), breast hyperplasia in353cases (92.88%),150cases of uterine fibroids (88.34%), diabetes in148cases (91.92%), allergic rhinitis,100cases (90.91%), thyroid nodules,89cases (89.90%), cervical spondylosis75cases (96.15%),Fatigue of patients with cervical spondylosis incidence was highest the fatigue between disease incidence was no statistical difference.
Conclusion:
According to the research methods used in this study is preliminary draw:
Examination of the different health status of populations, have fatigue symptoms occur, its incidence descending order of diseases, sub-health and the health of populations, reflecting extensive fatigue.
二、Research two:research on fatigue characteristics of different crowds of healthy medical examination Objective:
To evaluate of fatigue type, degree and characteristics among the crowd of health, sub health, disease
Method:Through the on-site survey methods, the use of a common international fatigue scale (FS-14) and self-developed research group fatigue self-rating scale (FSAS), Healthy people to Beijing xiaotangshan Hospital Medical Center from March2011to March2012examination, and to accept voluntary survey fatigue status of the investigation; Criteria (Annex1) in accordance with the healthy population belongs to the state of the study and draw the physical examination population health, sub-health and disease three categories, analysis, fatigue type, extent and characteristics of all types of people; to use Epdata3.1software to establish a database entry surveyed the crowd fatigue and physical examination data; use SPSS17.0various analysis.
Result:
The Institute's analysis of the object from" Research a "Physical examination population selected with fatigue(FS-14≥3)2496cases of people, male and1,284cases (51.44%), with an average age of40.40±9.70, and1212cases of women (48.56%), the average age to39.67±9.46; belong to the health status of167patients (6.69%) prevail healthy) belongs to the sub-health state,881cases (35.30%), which symptomatic sub-health the290cases (11.62%), symptoms-indicator sub-health crowd of591cases (23.68%); belongs disease crowd of1448cases (58.01%).
1Based on the fatigue characteristics of the fatigue scale (FS-14)
The three groups of health, sub-health, diseases fatigue score, the score of physical fatigue and mental fatigue scores were4.86±1.96,2.57±1.65,2.28±1.39;5.88±3.13,3.53± 2.25,2.35±1.71;5.52±2.78,3.35±2.11,2.17±1.59. The two physical fatigue scores and fatigue illness crowd highest among comparison.
1.1Fatigue characteristics of the healthy population (quasi-healthy people)
167cases of quasi-health crowd, Male and female body, brain and overall fatigue scores were2.60±1.63VS2.55±1.68.2.23±1.46VS2.34±1.30,4.83±1.94VS4.89±1.99, Higher in women than in men, but no significant difference; Fatigue scores from different ages,41to50-year-old age body, brain and overall fatigue scores the highest body of51to60years of age and overall fatigue scores lowest, to31～40-year-old mental ages fatigue lowest score, No significant difference between different ages (P>0.05); Distribution from the entry of the Fatigue Scale, mental fatigue"Did you feel the memory decline it?", The frequency of occurrence of the highest (60.37%), physical fatigue in"Do you feel the need to get more rest?" The frequency of occurrence of the highest (47.56%).
1.2The fatigue characteristics of the sub-health population
The881cases subhealth population (including symptoms of sub-health and symptoms-indicators of sub-health population), physical fatigue and general fatigue score of41to50-year-old age group is the highest, the lowest ages of51to60years old; mental fatiguethe highest score the ages of21to30-year-old,41to50years old age minimum; From the scale of entry distribution, in symptomatic subhealth crowd in "Do you feel the need to get more rest?" The frequency of occurrence as the highest(73.10%);Symptoms-indicative of sub-health population"Are you bothered by fatigue it?" The frequency of occurrence as the highest(53.64%).
The symptoms of sub-health population's physical, mental, and overall fatigue scores were higher than the symptoms-indicative of sub-health population, fatigue scores were4.37±2.14VS3.14±2.14N2.60±1.86VS2.20±1.61、6.94±3.22VS5.34±2.88, And significant difference (P<00.05)。
1.3The disease populations fatigue characteristics
1448cases of the disease population, male and female body and overall fatigue scores were3.31±2.10VS3.39±2.12.5.49±2.81VS5.55±2.76, Women than men, but no significant difference; Physical fatigue and general fatigue score of31to40-year-old age group is the highest, the lowest ages of51to60years old; ages of21to30-year-old was the highest score of mental fatigue, ages41to50years oldminimum; distribution from scale entry "Do you feel the need to get more rest?" Occurs at a frequency up to57.2%.
1.4Fatigue characteristics of common diseases
Frequency of occurrence of the top10of the disease, according to the fatigue score in descending order of the following order:
①physical fatigue:Cervical disease (3.79±2.43), high cholesterol(3.45±2.16) thyroid nodules (3.43±1.88), breast hyperplasia (3.41±2.17), diabetes (3.39±2.25) Allergic rhinitis (3.38±2.11), Hypertension(3.30±2.07), uterine fibroids (3.27±2.04) fatty liver (3.23±2.11), Chronic pharyngitis (3.21±2.12)
②Mental fatigue:Diabetes (2.31±1.67), Cervical disease (2.31±1.75), Chronic pharyngitis (2.28±1.62)、Breast hyperplasia (2.23±1.70)、Allergic rhinitis (2.19±1.67)、Uterine fibroids (2.18±1.66)、Hypertension (2.14±1.56)、thyroid nodules (2.13±1.72)、high cholesterol (2.11±1.57)、fatty liver (2.11±1.53)。
③Overall fatigue:Cervical disease (6.09±3.22)、diabetes (5.70±3.20)、breast hyperplasia (5.64±2.81)、high blood cholestero (5.56±2.81)、 thyroid nodules (5.56±2.85). allergic rhinitis (5.55±3.02)、chronic pharyngitis (5.49±2.83)、 uterine fibroids (5.47±2.80)、hypertension (5.44±2.76)、 fatty liver (5.33±2.70)
The distribution of specific entries, Hypertension, fatty liver, chronic pharyngitis, high cholesterol, diabetes, allergic rhinitis, thyroid nodules, cervical patients"Do you feel the need to get more rest?" the frequency of occurrence as the highest, Mental fatigue type are"Did you feel the memory decline it?" the frequency of occurrence is the highest.
Further analysis found that hypertension、diabetes、fatty liver:①physical examination, abnormal blood pressure in hypertensive patients3fatigue scores were higher than normal blood pressure in hypertensive patients;②physical examination, abnormal blood glucose levels in diabetic patients3fatigue scores were higher than normal blood sugar levels of diabetic patients, including physical fatigue score has a statistically significant difference between the two (P<0.05);③Fatty liver in patients with moderate to severe mental and overall fatigue scores were higher than in patients with moderate fatty liver;④Hypertension and diabetes, and high cholesterol patients physical, mental and overall fatigue scores were higher than mere hypertensive patients, including mental fatigue is a significant difference between the two groups;㏑elatively simple fatigue scores of the three groups of high blood pressure, high cholesterol and diabetes, physical fatigue scores for the highest mental fatigue and overall fatigue scores in patients with high cholesterol diabetes patients the highest.
2Fatigue characteristics based fatigue self-rating scale (FSAS)
Three groups of healthy (Quasi health), sub-health, diseases "physical fatigue" factor scores were27.67±22.21、30.81±23.31、33.86±23.62;"Fatigue on sleep the rest of the reaction" Factor scores, respectively29.79±27.21、26.08±26.35,28.51±27.13, two factor scores were significantly different in the three groups(P<0.05)。
2.1Healthy population fatigue characteristics of the (quasi-healthy people)
Gender fatigue characteristics of scores of female physical fatigue than men, mental fatigue, fatigue consequences, the degree of fatigue score, the rest of the reaction of fatigue on sleep, fatigue situational five factor scores men than women.
(1) The fatigue the type and extent of
167cases of fatigue type of quasi-healthy people score the same degree of fatigue to mild,56.71%physical fatigue, mental fatigue away from64.02%to63.41%, fatigue consequences.
(2) Characteristics of fatigue
Quasi-healthy people in the rest/sleep, unable to relieve fatigue response,29.07%of the people after a rest or sleep, fatigue can be alleviated; fatigue situational, only0.37%of the people is not obvious.
2.2Fatigue characteristics of sub-health population
881cases of sub-health population, male and female gender for the main types of physical fatigue score was30.47±23.26,31.16±23.38women than men, but no significant difference; between ages31to40years oldphysical fatigue, mental fatigue, fatigue consequences for the highest score,41to50-year-old mental fatigue, the highest score of the degree of fatigue, the score was no statistical difference between the highest score of51to60-year-old situational fatigue, different ages (P>0.05).
(1) The fatigue the type and extent of
The symptomatic sub-health and symptoms-indicators of sub-health fatigue type are the types of physical fatigue, the score of31.37±23.87,30.36±23.74, and there is a statistically significant difference, the symptomatic sub-health physical fatigue most obvious.
(2) Characteristics of fatigue
Above symptoms of sub-health symptoms-indicator sub-health in the reaction can not alleviate the fatigue of rest/sleep,36.58%of the people think that obvious; only31.09%of the people can alleviate the symptoms of fatigue performance; fatigue situational analysis found that the degree of mainly to more obvious symptoms of sub-health above symptoms-indicators sub-health40.64%40.85%.
2.3Disease populations fatigue characteristics.
1448cases of the disease population, male and female gender for the main types of physical fatigue score of33.64±32.19,33.67±32.25; higher in women than in men, but no significant difference; different between the ages of31to50years oldbetween fatigue type, extent and characteristics of the highest score, score no statistically significant difference (p>0.05).
(1) The fatigue the type and extent of
Disease populations belong to the physical fatigue score of33.86±23.62degree moderate physical fatigue moderate accounted for61.17%, the mental fatigue moderate (68.42%), the fatigue consequences moderate accounted for68.79%of overall fatigue moderate accounted for71.15%
(2) Characteristics of fatigue
Disease population, only29.07%of the people think, rest/sleep can ease the symptoms of fatigue; fatigue situational only0.37%of people think that is not obvious.
2.4Fatigue characteristics of the populations of the common diseases
The survey appears most long to see the10diseases were Hypertension, breast hyperplasia, fatty liver, chronic pharyngitis, high cholesterol, uterine fibroids, diabetes, allergic rhinitis, thyroid nodules, cervical spondylosis.
①Physical fatigue scores in descending order, cervical spondylosis> thyroid nodules>allergic rhinitis>chronic pharyngitis>high cholesterol> hypertension> breast hyperplasia> fatty liver> uterine fibroids> Diabetes.
②Mental fatigue scores, high to low for High cholestero> allergic rhinitis> hyperplasia>thyroid nodules> fatty liver>cervical spondylosis> hypertension>chronic pharyngitis> diabetes>uterine fibroids.
③Rest/sleep reaction to low Cervical disease> fatty liver> diabetes> high cholesterol>chronic pharyngitis> hypertension> thyroid nodules>allergic rhinitis> uterine fibroids>breast hyperplasia.
④Fatigue situational lowest is Cervical disease>high cholesterol> chronic pharyngitis>diabetes> hypertension> fatty liver> allergic rhinitis>hyperplasia>uterine fibroids> thyroid nodules.
⑤Fypertension blood pressure in patients with abnormal fatigue consequences and the degree of fatigue scores were higher than normal blood pressure, and both have a statistically significant difference (P<0.05); diabetes blood glucose in patients with abnormal fatigue situational score to56.92±25.11highnormal, with a significant difference (P<0.05).
Conclusion:
1Based on the fatigue characteristics of the fatigue scale (FS-14)
1.1Health (quasi-health) crowd fatigue characteristics:41to50-year-old age people prone to fatigue troubled, need more rest, memory loss and other performance, while the older body and overall fatigue will decrease.
1.2Sub-health population fatigue characteristics:male body fatigue than women obviously, is prone to need more rest and fatigue plagued discomfort performance, especially in sub-health population symptomatic than the symptoms-indicative of sub-health population prone to discomfort symptoms, resulting infatigue worse.
1.3Disease populations fatigue characteristics:the fatigue characteristics of women than men is more obvious, especially in the31to40-year-old, and need more than the rest of the body prone to fatigue performance.
1.4Common diseases fatigue characteristics:cervical spondylosis and physical examination, blood pressure, abnormal blood pressure, blood sugar of diabetics occurs when fatigue distress, need more rest, not enough energy, muscle strength decreases when hypertensive patients with diabetes and highlipids variety of diseases, fatigue symptoms are aggravated and simple hypertension, high cholesterol, diabetes three diseases are again more obvious symptoms of high blood cholesterol fatigue; severe fatty liver patients, inattention appears, the mind is not clear, memorydecline, mental fatigue performance significantly.
2Fatigue self-rating scale (FSAS)-based study of
2.1Comparison of health, sub-health, disease populations fatigue self-rating scale factor
scores
Healthy population Fatigue Scale (FSAS) fatigue characteristics①physical fatigue score low disease> sub-health> quasi health rigor exhaustion, tired consciously debilitating diseases the performance crowdsignificantly, followed by sub-health and prospective health.②fatigue reaction to rest on sleep scores in descending order of disease> Health> sub-health, disease populations due to the presence of their disease, and lead to the emergence of symptoms of fatigue can not be relieved by rest/sleep, can be seen symptoms of fatigue nothing to do with the rest/sleep, but related to the disease itself.
2.2Self-rating scale fatigue characteristics of the three groups of fatigue
2.2.1Fatigue types, extent and characteristics of quasi-healthy people
Quasi-healthy people to physical fatigue were mild, extent, prone to rigor, fatigue, weakness, mind unresponsive, depressed and tired of things do not want to do it anymore, and reduce the learning efficiency performance performance; anddepression, noisy, hot and stuffy environment, mental stress or negative emotions, such as the impact of easy fatigue symptoms get worse.
2.2.2Sub-health population fatigue types, extent and characteristics
Symptoms the sexual sub-health group than the symptoms-indicators of sub-health group prone, rigor, fatigue, weakness, frail feeling, lack of concentration, forgetfulness, slow to respond to phenomena; led to depression and do not want to get bored of thin gsto do so, reduce the efficiency of learning the consequences of fatigue performance; symptoms indicators of sub-health group that fatigue is not relieved by rest or sleep, obviously; symptoms of sub-health group because of the depression, the noisy and humid environments, nervous and external environ mentthe changes and negative emotions are likely to aggravate the symptoms. Positive mood and a good environment for an active role in the two sets of sub-health population to relieve fatigue.
2.2.3The disease populations fatigue type, extent and characteristics
Disease crowd to physical fatigue, and half the time there will be a rigor exhaustion, the performance of the limbs, muscle weakness, and lead to learning efficiency to reduce the consequences of fatigue performance; disease crowd fatigue has obvious situational specificity due to diseases caused by the body and spiritthe effect of pressure, so most of the people engaged in pleasant things can alleviate the symptoms of fatigue, and half of the people think that fatigue aggravated depressed or irritable when.
2.2.4Fatigue types, extent and characteristics of the common diseases
The cervical spondylosis prone rigor, fatigue, weakness, limbs, muscle weakness, still unable to ease the symptoms of fatigue after a rest/sleep, and depressed or irritable when fatigue aggravated; hyperlipidemia in patients prone to forget things unresponsive mind, learning efficiencyreduced.
Abnormal levels of blood pressure in patients with hypertension,May aggravate depression, tired of things do not want to do it anymore, and reduce the learning efficiency performance; abnormal blood sugar levels of diabetic patients, it may be easier because of the depression, noisy and humid environments, nervous, changes in the external environment and more sensitive to negative emotions lead to aggravation of fatigue; hypertension and diabetes and high cholesterol, rest/sleep does not alleviate the symptoms of fatigue and depression, noisy, hot and stuffy environment, nervous, changes in the external environment and the negative emotions the impact of further aggravation of the symptoms of fatigue.
Research three:
research on occurrence and symptom characteristics of fatigue and correlation analysis of the four seasons in the different crowds of healthy medical examination
Objective:
To explore the incidence rate and type,degree and characteristics of fatigue in different crowds of medical examination in different seasons.
Method:
Basis 《Twenty-four solar terms solution》 Start of the solar terms in four seasons in one year four established "(beginning of spring, beginning of summer and beginning of autumn, the beginning of winter) as the criteria for the classification of the four seasons (3.21to6.21in spring and6.22to9.22for the summer,9.23to12.21Fall12.22to3.20for wintcrclassified at the Four Seasons),2823cases of healthy people surveyed on the Beijing Xiaotangshan health examination center, analysis and comparison of the differences in the incidence and characteristics of the different seasons of the survey population fatigue, to explore the relationship between fatigue and seasons; use SPSS17.0kinds of descriptive analysis.
Results:
1Four Seasons in2823cases of the general healthy population
Age range of19to60years old, a spring average age of40.61±9.55years, a total of770cases were male and406(29.04%) and364females (25.54%); summer average age of38.19Q8.90years, a total of575cases were male296(21.17%) and279females (19.58%); fall an average age of40.04±9.739years, a total of1185cases were male and553(39.56%) and632females (44.35%); winter average age of40.20±9.28years of age, a total of293cases were male and143(10.23%) and150females (10.53%) in spring oldest, youngest summer.
2Distribution healthy crowd of fatigue at the Four Seasons
2.1Different health status in the occurrence of the Four Seasons fatigue
Healthy people in the winter fatigue happens is up to90.91%, the sub-health population occurred in the summer of fatigue up to89.57%, disease crowd highest in winter and accounted for92.99percent, the lowest incidence of sub-health, disease, the two groups are spring fatigue of the crowd,two groups in different seasons fatigue happens there is a statistically significant difference (P<0.05).
2.2Four Seasons the fatigue scales FS-14fatigue characteristics
2.2.1The fatigue characteristics of the three groups
①healthy people physical fatigue mental fatigue scores were higher than the highest score in the autumn.②sub-health population physical, mental and general fatigue there is a statistically significant difference (P<0.05).③Disease populations in different seasons, physical fatigue in the summer the highest mental fatigue and general fatigue was highest in autumn, Four Seasons physical fatigue than mental fatigue, fatigue characteristics there is a statistically significant difference (P<0.05).
2.2.2Fatigue characteristics of the different seasons of the populations of the common diseases
①hypertensive patients found fatigue scores in different seasons, and physical fatigue in the spring when the lowest maximum winter, mental fatigue highest in winter and lowest in spring, and there is a significant difference (P<0.05).②breast hyperplasia, high cholesterol, diabetes, cervical spondylosis, fatigue scores in different seasons found that physical fatigue is highest in summer and lowest in winter, and there is a significant difference (P<0.05)③ patients with allergic rhinitis fatigue scores in different seasons found that mental fatigue is highest in the autumn, and there is a significant difference (P<0.05).
2.3Fatigue characteristics of the different seasons based on fatigue self-rating scale (FSAS)
2.3.1Fatigue type and extent of the group at the Four Seasons:①physical fatigue: physical fatigue factor for health and sub-health population score highest in autumn; the healthy populations summer the lowest score, health groups lowest score in winter; types of labor in the two populations seasons there is a statistically significant difference (P <0.05);The degree of physical fatigue, the health and subhealth physical fatigue for mild autumn highest disease population and physical fatigue as moderate in autumn, three groups there is a significant difference (P<0.05).②mental fatigue:health, sub-health population mental fatigue factor scores was statistically significant (P<0.05), the two groups are the highest in autumn, the degree of mental fatigue to mild.③fatigue consequences:health consequences of sub-health population fatigue factor scores was statistically significant (P <0.05), are highest in autumn, a mild degree of fatigue consequences diseases and sub-health population statistically significant (P<0.05),(4) the degree of fatigue Score:health, sub-health population the degree of fatigue scores was statistically significant (P<0.05) in the factor scores are highest in autumn, health and sub-health population in the degree of fatigue to mild main disease populations to moderate.
2.3.2Fatigue characteristics of each group at the Four Seasons:①the reaction of the fatigue of the rest/sleep:health, sub-health population fatigue response to rest/sleep factor scores was statistically significant (P<0.05), are the highest in autumn. The②fatigue situational:health, disease, health groups fatigue situational factor scores was statistically significant (P<0.05), healthy population highest in the winter, disease, health groups, the highest in the fall.
2.3.3Occurrence of fatigue symptoms of common diseases at the Four Seasons:①hypertensive patients with fatigue scores in different seasons, fatigue types belong to body fatigue, the highest in the fall, fatigue consequences of fatigue on sleep the rest of the reaction, fatigue situational significant difference (P<0.05).②chronic pharyngitis patients found that fatigue type belonging to physical fatigue fatigue scores in the different seasons, and in the fall when the highest physical fatigue, mental fatigue, fatigue consequences, the degree of fatigue total score of fatigue on sleep the rest of the reaction a significant difference (P<0.05).(3)in patients with breast hyperplasia fatigue scores in the different seasons of spring and autumn obvious physical fatigue, mental fatigue of the summer and winter fatigue situational significant difference (P<0.05).④high blood cholesterol in patients with fatigue scores in the different seasons, only fatigue the scenario was no significant difference (P>0.05).⑤diabetes fatigue scores in different seasons fatigue type of mental fatigue, fatigue consequences, the degree of fatigue scores statistically significant difference (P<0.05).⑥patients with allergic rhinitis found fatigue scores in different seasons, spring and winter mainly physical fatigue, mental fatigue in the summer and fall mainly fatigue situational significant difference (P<0.05).
Conclusion:
1Distribution healthy crowd of fatigue at the Four Seasons
Predilection sub-health population in the summer when the most obvious symptoms of fatigue, disease crowd in the winter the most obvious symptoms of fatigue; women's spring and summer the most obvious symptoms of fatigue, people in the41to60age group in the spring when the fatigue symptoms most prominentThe fatigue symptoms eased autumn.
2Fatigue Scale (FS-14) in the Four Seasons fatigue characteristics
2.1The fatigue characteristics of the three groups:①the healthy population plagued fatigue, rest feel powerless, not enough energy and overall fatigue gradually increased as the seasons change, will be eased in the winter. The②subhealth crowd symptoms of fatigue with the seasons and relieve fatigue symptoms lightest in the fall, fatigue plagued by symptoms of sub-health population in the summer, need more rest feel powerless, energy is not enough body, fatigue, general fatigue performance than obvious symptoms-sub-health population. The③disease groups in summer plagued fatigue, need more rest feel powerless, energy is not enough physical fatigue performance of the most obvious; inability to concentrate in the fall when the mind is not clear, memory decline, overall fatigue is the most obvious.
2.2Common characteristics of the different seasons of the disease population fatigue:①the hypertensive patients plagued fatigue, you need plenty of rest to feel powerless, energy is not enough performance, most obvious in the spring; winter was attention difficulties, memory loss, loss of interest in the habit of doing things the most obvious.②breast hyperplasia, high cholesterol, diabetes, cervical spondylosis easy in the summer when fatigue plagued need more rest feel powerless, energy is not enough performance③patients with allergic rhinitis easy in the fall to attention difficulties, the mind is not clear, memory loss, the most obvious manifestations of the habit of doing things lose interest.
3Fatigue characteristics of the different seasons based on fatigue self-rating scale (FSAS)
3.1Group at the Four Seasons in the type and extent of fatigue:①physical fatigue:the three groups in the fall when rigor is weak, tired, weak performance of the degree of the heaviest, the fatigue symptoms lightest winter.②mental fatigue:health, health groups appear inattention, unresponsive, forget things, and other symptoms tended to increase in the summer to autumn mental fatigue, mental fatigue autumn to winter on a downward trend, while the disease crowd from summer to winter there are a growing trend.①Fatigue consequences: health and sub-health population in the summer to the fall, appear depressed, tired of things do not want to do it anymore, and reduce the learning efficiency performance tended to increase, a downward trend in the autumn to winter fatigue consequences, disease groups from
以整体观念和辨证论治为基本特点的中医学,对于疲劳的干预,尤其是机理尚不明确的亚健康状态的疲劳,具有较大的优势。因此,本研究拟通过对体检中心健康体检人群疲劳状态的调查,分析健康、亚健康及不同疾病人群中疲劳状态,探讨疲劳特点与常规体检指标之间的相关性,为进一步探讨疲劳的发生率、疲劳的类型特点及其可能的发生机理,以及未来的中医药干预研究提供依据。
研究一健康体检人群疲劳症状的发生率
目的：
通过对健康体检人群疲劳状态的调查,分析健康、亚健康及疾病人群的疲劳症状发生率。
方法：
通过现场调查的方法,运用国际上通用的疲劳量表(FS-14),对2011年3月至2012年3月间来北京小汤山医院体检中心体检并自愿接受调查的健康体检人群进行疲劳状况调查,并依本研究拟定疲劳症状判断标准(FS>3)、健康体检人群所属状态判定标准(见附录1)、流程及体检中心的体检报告,将体检人群分为健康、亚健康及疾病三大类,分析疲劳在各类人群中的发生情况；运用Epdata3.1软件建立数据库,录入所调查人群的疲劳及相关体检数据；运用SPSS17.0进行各种描述性分析。
结果：
1.健康体检人群的一般情况及健康状态分布
1.12823例健康体检人群的健康状态情况
符合调查人群纳入标准者共2823例,年龄范围为19～60岁,平均年龄为39.84±9.51岁；其中男性1398人(49.5%),平均年龄40.23±9.72岁,女性1425例(50.5%),平均年龄39.92±9.80岁。
2823例人群中,属于健康人群者204例(7.23%),其中标准健康人群13例(0.46%),准健康人群为191例(6.77%)；属于亚健康人群者1053例(37.30%),其中症状性亚健康人群为324例(11.48%),指标性亚健康人群为52例(1.84%),症状-指标性亚健康人群为677例(23.98%)；属于疾病人群者1566例(55.47%),其中出现频率排在前十位者为高血压、慢性咽炎、脂肪肝(中度以上)、乳腺增生(中度以上)、高血脂、子宫肌瘤、糖尿病、过敏性鼻炎、甲状腺结节、颈椎病。
2.不同健康状态体检人群的疲劳发生率
2.1健康人群的疲劳发生情况
204例健康人群(包括标准健康和准健康人群)中,有167例存在有疲劳的情况,其疲劳发生率为81.86%
2.2亚健康人群的疲劳发生情况
1053例亚健康人群(包括症状性亚健康、指标性亚健康、症状-指标性亚健康)中,有881例存在有疲劳的情况,其疲劳发生率为83.67%；其中症状亚健康疲劳发生率为89.50%,症状-指标性亚健康疲劳发生率为87.30%。
2.3疾病人群的疲劳发生情况
1566例疾病人群中(包括患有不同疾病的所有人群)中,有1448例存在有疲劳的情况,其疲劳发生率为92.46%。
排在前10位的疾病患者出现疲劳的例数及发生率依次为,高血压480例(93.00%)、脂肪肝277例(92.00%)、慢性咽炎272例(89.77%)、高血脂262例(92.58%)、乳腺增生353例(92.88%)、子宫肌瘤150例(88.34%)、糖尿病148例(91.92%)、过敏性鼻炎100例(90.91%)、甲状腺结节89例(89.90%)、颈椎病75例(96.15%),其中以有颈椎病的患者的疲劳发生率为最高,各疾病之间的疲劳发生率无统计学差异。
结论：
根据本研究所采用的研究方法初步得出：不同健康状态的体检人群,均有疲劳症状的发生,其发生率由高到低依次为疾病、亚健康及健康人群,反映了疲劳发生的广泛性。
研究二不同健康体检人群的疲劳特点研究
目的：
评价健康、亚健康、疾病三类人群的疲劳类型、程度及特征方法：
通过现场调查的方法,运用国际上通用的疲劳量表(FS-14)及课题组自行研制的疲劳自评量表(FSAS),对2011年3月至2012年3月间来北京小汤山医院体检中心体检,并自愿接受调查的健康体检人群进行疲劳状况的调查;依据本研究拟定的健康体检人群所属状态判定标准(见附录1),将体检人群分为健康、亚健康及疾病三大类,分析、比较各类人群的疲劳发生类型、程度及特点；运用Epdata3.1软件建立数据库,录入所调查人群的疲劳及相关体检数据；运用SPSS17.0进行各种分析。
结果：
本研究所分析的对象是从“研究一”的体检人群中选取的具有疲劳(FS总分≥3分)的2496例人群,其中男性1284例(51.44%),平均年龄为40.40±9.70,女性1212例(48.56%),平均年龄为39.67±9.46；属于健康状态者167例(6.69%)全部为准健康者)属于亚健康状态者881例(35.30%),其中症状性亚健康者为290例(11.62%),症状-指标性亚健康人群为591例(23.68%)；属于疾病人群者1448例(58.01%)
1基于疲劳量表(FS-14)疲劳特点的研究
健康、亚健康、疾病三组人群的疲劳总分、躯体疲劳分值及精神疲劳分值分别为4.86±1.96、2.57±1.65、2.28±1.39；5.88±3.13、3.53±2.25、2.35±1.71；5.52±2.78、3.35±2.11、2.17±1.59。其中以疾病人群的躯体疲劳分值及疲劳总分为最高,三者之间的比较
1.1健康人群(准健康人群)的疲劳特点
167例准健康人群中,男、女两性的躯体、脑力及及总体疲劳分值分别为2.60±1.63VS2.55±1.68、2.23±1.46VS2.34±1.30、4.83±1.94VS4.89±1.99,女性高于男性,但无统计学差异；从不同年龄段的疲劳分值看,以41-50岁年龄段者躯体、脑力及总体疲劳的分值为最高,以51-60岁年龄段的躯体及总体疲劳分值为最低,以31-40年龄段者的岁脑力疲劳分值为最低,不同年龄段的比较无统计学差异(P>0.05)；从疲劳量表的条目分布看,脑力疲劳中以“你感觉到记忆力下降了吗?”出现的频率为最高(60.37%),躯体疲劳中以“你觉得需要多休息吗?”出现的频率为最高(47.56%)。
1.2亚健康人群的疲劳特点
881例亚健康人群中(包括症状亚健康和症状-指标亚健康人群),躯体疲劳和总体疲劳的分值以41-50岁年龄段为最高,以51-60岁年龄段为最低；脑力疲劳的分值以21-30岁年龄段为最高,41-50岁年龄段为最低；从量表的条目分布来看,在症状性亚健康人群中,以“你觉得需要多休息吗?”出现的频率为最高(73.10%)；在症状-指标性亚健康人群中以“你有被疲劳困扰的情况吗?”出现的频率为最高(53.64%)
症状亚健康人群的躯体、脑力及总体疲劳的分值均高于症状-指标性亚健康人群,疲劳分值分别为4.37±2.14VS3.14±2.14、2.60±1.86VS2.20±1.61、6.94±3.22VS5.34±2.88,并且有统计学差异(P<0.05)
1.3疾病人群的疲劳特点
1448例疾病人群中,男、女两性的躯体及总体疲劳的分值分别为3.31±2.10VS3.39±2.12、5.49±2.81VS5.55±2.76,女性均高于男性,但无统计学差异;躯体疲劳和总体疲劳的分值以31～40岁年龄段为最高,以51～60岁年龄段为最低；脑力疲劳的分值以21～30岁年龄段为最高,以41～50岁年龄段为最低；从量表条目的分布来看,以“你觉得需要多休息吗?”出现的频率为最高57.2%。
1.4常见疾病的疲劳特点
出现频率排在前10位的疾病中,根据其疲劳分值由高到低的顺序依次如下：①躯体疲劳：颈椎病(3.79±2.43)、高血脂(3.45±2.16)、甲状腺结节(3.43±1.88)、乳腺增生(3.41±2.17)、糖尿病(3.39±2.25)、过敏性鼻炎(3.38±2.11)、高血压(3.30±2.07)、子宫肌瘤(3.27±2.04)、脂肪肝(3.23±2.11)、慢性咽炎(3.21±2.12)。②精神疲劳：糖尿病(2.31±1.67)、颈椎病(2.31±1.75)、慢性咽炎(2.28±1.62)乳腺增生(2.23±1.70)、过敏性鼻炎(2.19±1.67)、子宫肌瘤(2.18±1.66)、高血压(2.14±1.56)、甲状腺结节(2.13±1.72)、高血脂(2.11±1.57)、脂肪肝(2.11±1.53)。③总体疲劳：颈椎病(6.09±3.22)、糖尿病(5.70±3.20)、乳腺增生(5.64±2.81)高血脂(5.56±2.81)、甲状腺结节(5.56±2.85)、过敏性鼻炎(5.55±3.02)、慢性咽炎(5.49±2.83)、子宫肌瘤(5.47±2.80)、高血压(5.44±2.76)、脂肪肝(5.33±2.70)。
具体条目的分布,高血压、脂肪肝、慢性咽炎、高血脂、糖尿病、过敏性鼻炎、甲状腺结节、颈椎病患者均以“你觉得需要多休息吗?”出现的频率为最高,精神疲劳类型均以“你感觉到记忆力下降了吗?”出现的频率为最高。
对高血压、糖尿病、脂肪肝的进一步分析比较发现：①体检时血压异常的高血压患者的3个疲劳分值均高于血压正常的高血压患者；②体检时血糖水平异常的糖尿病患者3个疲劳分值均高于血糖水平正常的糖尿病患者,其中躯体疲劳分值在两者间具有统计学差异(P<0.05)；③重度脂肪肝患者的脑力及总体疲劳分值均高于中度脂肪肝患者；④高血压合并糖尿病及高血脂患者的躯体、脑力及总体疲劳的分值均高于单纯的高血压患者,其中脑力疲劳在两组间有统计学差异；⑤比较单纯出现高血压、高血脂及糖尿病三组人群的疲劳分值,躯体疲劳分值以高血脂患者为最高,脑力疲劳及总体疲劳分值以糖尿病患者为最高。
2基于疲劳自评量表(FSAS)疲劳特点的研究
健康(准健康)、亚健康、疾病三组人群的“躯体疲劳”因子的分值分别为27.67±22.21、30.81±23.31、33.86±23.62；“疲劳对睡眠休息的反应”因子分值分别29.79±27.21、26.08±26.35、28.51±27.13,两个因子的分值在三组人群中均有统计学差异(P<0.05)。
2.1健康人群(准健康人群)疲劳特点
两性疲劳特点分值女性躯体疲劳高于男性,精神疲劳、疲劳后果、疲劳程度总分、疲劳对睡眠休息的反应、疲劳的情境性5个因子分值男性均高于女性。(1)疲劳的类型及程度
167例中,准健康人群疲劳类型分值一样,疲劳程度以轻度为主,躯体疲劳为56.71%,精神疲劳程为64.02%,疲劳后果为63.41%。(2)疲劳的特征
准健康人群在休息/睡眠无法缓解疲劳的反应中,有29.07%的人经过休息或者睡眠后,疲劳可以得到缓解；疲劳情境性中,仅有0.37%的人不明显。
2.2亚健康人群疲劳特点
881例亚健康人群中,男、女两性以躯体疲劳为主要类型,分值为30.47±23.26、31.16±23.38女性高于男性,但无统计学差异；不同年龄段之间,31～40岁的躯体疲劳、精神疲劳、疲劳后果分值最高,41-50岁的精神疲劳、疲劳程度分值最高,51～60岁的疲劳的情境性分值最高,不同年龄段之间得分无统计学差异(P>0.05)
(1)疲劳的类型及程度
症状性亚健康及症状-指标亚健康疲劳类型均属于躯体疲劳类型,分值为31.37±23.87、30.36±23.74,并且有统计学差异,症状性亚健康躯体疲劳最明显。
(2)疲劳的特征
症状-指标性亚健康在休息/睡眠无法缓解疲劳的反应中高于症状亚健康,有36.58%的人认为明显；仅有31.09%的人能够缓解疲劳症状的表现；在疲劳情境性分析发现,程度以比较明显为主,其中症状亚健康为40.85%高于症状-指标亚健康40.64%。
2.3疾病人群疲劳特点
1448例疾病人群中,男、女两性以躯体疲劳为主要类型,分值为33.64±32.19、33.67±32.25；女性高于男性,但无统计学差异；不同年龄段之间,31-50岁之间疲劳类型、程度及特征分值最高,得分无统计学差异(P>0.05)
(1)疲劳的类型及程度
疾病人群属于躯体疲劳,分值为33.86±23.62,程度以中度为主,躯体疲劳中度占61.17%,精神疲劳中度占68.42%,疲劳后果中度占68.79%,总体疲劳中度占71.15%
(2)疲劳的特征
疾病人群中仅有29.07%的人认为,休息／睡眠可以缓解疲劳症状；疲劳情境性仅有0.37%的人认为不明显
2.4常见疾病人群的疲劳特点
本次调查出现最为长见的10种疾病分别为高血压、乳腺增生、脂肪肝、慢性咽炎、高血脂、子宫肌瘤、糖尿病、过敏性鼻炎、甲状腺结节、颈椎病。
①躯体疲劳分值由高至低为,颈椎病>甲状腺结节>过敏性鼻炎>慢性咽炎>高血脂>高血压>乳腺增生>脂肪肝>子宫肌瘤>糖尿病
②精神疲劳分值,由高至低为,高血脂>过敏性鼻炎>乳腺增生>甲状腺结节>脂肪肝>颈椎病>高血压>慢性咽炎>糖尿病>子宫肌瘤
③休息/睡眠反应由高至低为,颈椎病>脂肪肝>糖尿病>高血脂>慢性咽炎>高血压>甲状腺结节>过敏性鼻炎>子宫肌瘤>乳腺增生
④疲劳情境性由高至低为,颈椎病>高血脂>慢性咽炎>糖尿病>高血压>脂肪肝>敏性鼻炎>乳腺增生>子宫肌瘤>甲状腺结节
⑤高血压血压异常患者,疲劳后果及疲劳程度总分均高于血压正常者,两者具有统计学差异(P<0.05)；糖尿病血糖异常患者,在疲劳情境性的分值为56.92±25.11,高于正常者,具有统计学差异(P<0.05)。
结论：
1基于疲劳量表(FS-14)的疲劳特点研究
1.1健康(准健康)人群疲劳特点：41-50岁年龄段的人容易出现疲劳困扰、需要多休息、记忆力下降等的表现,而年龄越大躯体及总体疲劳会有所下降。
1.2亚健康人群疲劳特点：男性躯体疲劳要比女性明显,容易出现需要多休息并且被疲劳困扰的不适表现,尤其是症状性亚健康人群会比症状-指标性亚健康人群容易出现不适症状表现,导致疲劳感加重。
1.3疾病人群疲劳特点：女性比男性的疲劳特点更为明显,尤其在31-40岁的时候,容易出现需要多休息的躯体疲劳表现。
1.4常见疾病疲劳特点：颈椎病及体检时高血压、糖尿病患者血压、血糖异常时出现疲劳困扰、需要多休息、精力不够、肌肉力量减小等躯体疲劳表现最明显,当高血压患者合并糖尿病及高血脂多种疾病时,疲劳症状均会加重,而单纯高血压、高血脂、糖尿病三种疾病又以高血脂疲劳症状更为明显；重度脂肪肝患者,出现注意力不集中、头脑不清晰、记忆力下降等,脑力疲劳的表现明显。
2基于疲劳自评量表(FSAS)疲劳特点的研究
2.1健康、亚健康、疾病人群的疲劳自评量表各因子分值的比较
健康体检人群的疲劳量表(FSAS)疲劳特点显示,①躯体疲劳分值由高至低分别为疾病>亚健康>准健康,说明四肢酸软疲乏无力、体力不支、自觉身体虚弱的表现疾病人群最明显,其次是亚健康及准健康。②疲劳对睡眠休息的反应分值由高至低依次为疾病>健康>亚健康,所以疾病人群由于有自身疾病存在,而导致疲劳症状的出现无法通过休息／睡眠得到缓解,由此可知疲劳症状与休息／睡眠无关,而是与疾病本身有关。
2.2三组人群疲劳自评量表的疲劳特点
2.2.1准健康人群疲劳类型、程度及特征
准健康人群以躯体疲劳为主,程度均为轻度,容易出现四肢酸软、疲乏无力、头脑反应迟钝、情绪低落、对事情感到厌烦不想再做下去、学习效率减低等的表现的表现；并且在情绪低落、嘈杂及闷热环境、精神紧张或负面情绪等的影响而容易使疲劳症状加重。
2.2.2亚健康人群疲劳类型、程度及特征
症状性亚健康组比症状-指标亚健康组容易出现,四肢酸软、疲乏无力、身体虚弱的感觉明显、注意力不集中、健忘、反应迟缓等现象；导致出现情绪低落、对事情感到厌烦不想再做下去、学习效率减低等的疲劳后果表现；而症状-指标性亚健康组认为休息或者睡眠后,疲劳无法缓解明显；因为情绪低落、嘈杂及闷热环境、精神紧张等,外环境的变化及负面情绪容易加重症状。
2.2.3疾病人群疲劳类型、程度及特征
疾病人群以躯体疲劳为主,有一半时间会出现四肢酸软疲乏无力、四肢肌肉无力的表现,并且导致学习效率降低的疲劳后果表现；疾病人群疲劳具有明显的情境特异性,由于疾病造成躯体及精神的压力影响,所以大部分人认为从事愉快的事情可以减轻疲劳症状,并且有一半人认为情绪低落或急躁时感到疲劳加重。
2.2.4常见疾病疲劳类型、程度及特征
颈椎病患者容易出现四肢酸软、疲乏无力、四肢肌肉无力,经过休息/睡眠後仍然无法缓解疲劳症状,并且情绪低落或急躁时感到疲劳加重；高血脂患者容易出现忘事、头脑反应迟钝、学习效率降低。
高血压患者血压水平异常时,可能会加重情绪低落、对事情感到厌烦不想再做下去、学习效率减低等的表现；糖尿病患者血糖水平异常时,可能更容易因为情绪低落、嘈杂及闷热环境、精神紧张等,外环境的变化及负面情绪更加敏感导致疲劳感加重；当高血压合并了糖尿病及高血脂时,出现休息／睡眠无法缓解疲劳症状,并且在情绪低落、嘈杂及闷热环境、精神紧张等,外环境的变化及负面情绪的影响造成疲劳症状进一步的加重。
研究三不同健康体检人群疲劳发生及症状特点与四季相关性分析
目的：
探讨不同健康体检人群在不同季节的疲劳症状发生率及疲劳的类型、程度和特点。
方法：
依据《二十四节气解》,以一年中四季开始的节气“四立”(立春、立夏、立秋、立冬)作为四季的划分标准(3.21-6.21为春季,6.22-9.22为夏季,9.23-12.21为秋季,12.22-3.20为冬季),对北京小汤山健康体检中心调查的2823例健康体检人群划归于四季,分析比较在不同季节的调查人群疲劳发生率及特点的差异,探讨疲劳与季节的关系；运用SPSS17.0进行各种描述性分析。
结果：
1四季中2823例健康体检人群的一般情况
年龄范围为19～60岁,春季平均年龄40.61±9.55岁,共770例,其中男性406人(29.04%)女性364人(25.54%)；夏季平均年龄38.19±8.90岁,共575例,其中男性296人(21.17%)、女性279人(19.58%)；秋季平均年龄40.04±9.739岁,共1185例,其中男性553人(39.56%)、女性632人(44.35%)；冬季平均年龄40.20±9.28岁,共293例,其中男性143人(10.23%)女性150入(10.53%)春季年龄最大,夏季年龄最小。
2健康体检人群的疲劳发生在四季中的分布
2.1不同健康状态在四季疲劳的发生情况
健康人群在冬季疲劳发生情况最高为90.91%,亚健康人群在夏季疲劳发生情况最高为89.57%,疾病人群冬季最高占92.99%,其中亚健康、疾病人群两组组均为春季疲劳发生情况最低,两组在不同季节中疲劳发生情况存在统计学差异(P<0.05)。
2.2四季中疲劳量表FS-14的疲劳特点情况
2.2.1三组人群的疲劳特点
①健康人群躯体疲劳分值均高于脑力疲劳,在秋季分值最高。②亚健康人群躯体、脑力及总体疲劳均存在统计学差异(P<0.05)。③疾病人群在不同季节中躯体疲劳在夏季最高、脑力疲劳及总体疲劳秋季最高,四季躯体疲劳高于脑力疲劳,疲劳特点均存在统计学差异(P<0.05)。
2.2.2常见疾病人群的不同季节疲劳特点
①高血压患者在不同季节疲劳分值发现,躯体疲劳在春季时最高冬季最低,脑力疲劳冬季最高春季最低,并且存在统计学差异(P<0.05)。②乳腺增生、高血脂、糖尿病、颈椎病患者在不同季节疲劳分值发现,躯体疲劳在夏季时最高冬季最低,并且存在统计学差异(P<0.05)③过敏性鼻炎患者在不同季节疲劳分值发现,脑力疲劳在秋季时最高,并且存在统计学差异(P<0.05)。
2.3基于疲劳自评量表(FSAS)的不同季节疲劳特点情况
2.3.1各组人群在四季中疲劳类型及程度：①躯体疲劳：健康及亚健康人群躯体疲劳因子分值在秋季最高；健康人群夏季分值最低,亚健康人群冬季分值最低；两组人群四季中劳类型存在统计学差异(P<0.05)；躯体疲劳程度比较发现,健康及亚健康躯体疲劳为轻度在秋季时最高,疾病人群躯体疲劳为中度在秋季时最高,三组人群存在统计学差异(P<0.05)。②精神疲劳：健康、亚健康人群精神疲劳因子分值有统计学意义(P<0.05),均为秋季最高,两组人群精神疲劳程度以轻度为主。③疲劳后果：健康、亚健康人群疲劳后果因子分值有统计学意义(P<0晒.05),均为秋季最高,在疲劳后果程度中以轻度为主,而疾病与亚健康人群有统计学意义(P<0.05)④疲劳程度总分：健康、亚健康人群疲劳程度总分因子分值有统计学意义(P<0.05),均为秋季最高,在疲劳程度中健康及亚健康人群以轻度为主,疾病人群以中度为主。
2.3.2各组人群在四季中的疲劳特征：①疲劳对休息/睡眠的反应：健康、亚健康人群疲劳对休息/睡眠的反应因子分值有统计学意义(P<0.05),均为秋季最高。②疲劳情境性：健康、疾病、亚健康人群疲劳情境性的因子分值有统计学意义(P<0.05),健康人群在冬季最高,疾病、亚健康人群在秋季最高。
2.3.3常见疾病的疲劳症状在四季发生情况：①高血压患者在不同季节疲劳分值发现,疲劳类型属于躯体疲劳,在秋季时最高,疲劳后果、疲劳对睡眠休息的反应、疲劳的情境性有统计学差异(P<0.05)。②慢性咽炎患者在不同季节疲劳分值发现,疲劳类型属于躯体疲劳,在秋季时最高,躯体疲劳、精神疲劳、疲劳后果、疲劳程度总分、疲劳对睡眠休息的反应有统计学差异(P<0.05)。③乳腺增生患者在不同季节疲劳分值发现,春秋两季躯体疲劳明显,夏冬两季精神疲劳明显,疲劳的情境性有统计学差异(P<0.05)。④高血脂患者在不同季节疲劳分值发现,仅疲劳的情境无统计学差异(P>0.05)。⑤糖尿病患者在不同季节疲劳分值发现,疲劳类型以精神疲劳为主,疲劳后果、疲劳程度总分有统计学差异(P<0.05)。⑥过敏性鼻炎患者在不同季节疲劳分值发现,春冬两季以躯体疲劳为主,夏秋两季以精神疲劳为主,疲劳的情境性有统计学差异(P<0.05)
结论：
1健康体检人群的疲劳发生在四季中的分布
亚健康人群在夏季时好发疲劳症状最为明显,疾病人群在冬季时疲劳症状最为明显；女性春夏两季疲劳症状最为明显,在41-60岁年龄段的人在春季时疲劳症状最为突出到秋季时疲劳症状会有所缓解。
2四季中疲劳量表FS-14的疲劳特点情况
2.1三组人群的疲劳特点：①健康人群出现疲劳困扰、需要多休息感到力不从心、精力不够及总体疲劳随着季节变化逐渐增高,在冬季会有所缓解。②亚健康人群疲劳症状会随着季节而缓解,在秋季时疲劳症状最轻,其中症状亚健康人群在夏季出现疲劳困扰、需要多休息感到力不从心、精力不够等躯体、疲劳总体疲劳的表现均比症状-亚健康人群要明显。③疾病人群在夏季时出现疲劳困扰、需要多休息感到力不从心、精力不够等躯体疲劳表现最明显；在秋季时注意力无法集中、头脑不清晰、记忆力下降等总体疲劳最明显。
2.2常见疾病人群的不同季节疲劳特点：①高血压患者出现疲劳困扰、需要多休息感到力不从心、精力不够等表现,在春季时最为明显；而在冬季时感到注意力困难、记忆力下降,对习惯做的事情失去兴趣等表现最为明显。②乳腺增生、高血脂、糖尿病、颈椎病患者容易在夏季时出现疲劳困扰、需要多休息感到力不从心、精力不够等表现③过敏性鼻炎患者容易在秋季出现注意力困难、头脑不清晰、记忆力下降、对习惯做的事情失去兴趣等表现最为明显。
3基于疲劳自评量表(FSAS)的不同季节疲劳特点情况
3.1各组人群在四季中疲劳类型及程度：①躯体疲劳：三组人群在秋季时四肢酸软乏力、体力不支、身体虚弱等表现程度最重,在冬季时疲劳症状最轻。②精神疲劳：健康、亚健康人群出现注意力不集中、反应迟钝、忘事等症状,在夏季至秋季精神疲劳有增高趋势,秋季至冬季精神疲劳有下降趋势,而疾病人群从夏季至冬季时有增长的趋势。③疲劳后果：健康及亚健康人群在夏季至秋季,出现情绪低落、对事情感到厌烦不想再做下去、学习效率减低等的表现有增高趋势,秋季至冬季疲劳后果有下降趋势,疾病人群从春季至夏季出现下降趋势,而从夏季至冬季出现增长的趋势。④疲劳程度总分：健康及亚健康人群在夏季至秋季疲劳程度逐渐加重,秋季至冬季疲劳程度逐渐减轻,而疾病人群只有在夏季时疲劳程度最轻。
3.2各组人群在四季中的疲劳特征：①疲劳对休息/睡眠的反应：健康及亚健康人群在夏季时,睡眠或休息后对疲劳缓解程度缓解不明显,而疾病人群可能是因为自身疾病原因,一年四季中睡眠或休息后对疲劳缓解程度趋势并不明显。②疲劳情境性：健康人群在冬季时对嘈杂的环境、紧张情绪、从事愉快的事情疲劳症状可以缓解等表现最为明显,从夏季至冬季有逐渐增加的趋势；而疾病及亚健康人群均在秋季时,因为不同环境或情绪导致疲劳症状加重的表现最明显。
3.3常见疾病的疲劳症状在四季发生情况：①高血压患者在秋季时出现情绪低落、对事情感到厌烦不想再做下去、学习效率减低、经过睡眠或休息后对疲劳缓解程度缓解不明显,并且容易因为周边环境及负面情绪加重疲劳症状；②慢性咽炎患者在秋季时,出现四肢无力、注意力不集中、健忘、反应迟缓、睡眠或休息后对疲劳缓解程度缓解不明显等现象最为明显。③乳腺增生患者在春秋两季感觉躯体疲乏无力较为明显。在夏冬两季注意力不集中、健忘、反应迟缓等现象表现比较明显,并且对于嘈杂闷热环境、紧张情绪等负面情绪加重疲劳症状更为明显。④高血脂患者在春、夏、秋季节容易出现注意力不集中、健忘、反应迟缓等精神疲劳现象表现比较明显,在冬季时容易出现疲乏无力等的躯体疲劳表现明显,在秋季时容易出现情绪低落、对事情感到厌烦不想再做下去、学习效率减低、睡眠或休息后对疲劳缓解程度无法缓解等的表现明显。⑤糖尿病患者容易出现注意力不集中、健忘、反应迟缓等精神疲劳现象表现比较明显,在秋季时容易出现情绪低落、对事情感到厌烦不想再做下去、学习效率减低等的表现明显。⑥过敏性鼻炎患者在秋季时对于嘈杂闷热环境、紧张情绪等负面情绪加重疲劳症状更为明显。
研究四不同健康体检人群疲劳状态与体检指标相关性的探索
目的：
探讨健康、亚健康、疾病三类健康体检人群的疲劳状态与体检指标间的相关性方法：
根据疲劳量表(FS-14)测评结果,疲劳总分值≥3且具有疲劳症状的体检人群,采用疲劳自评量表(FSAS)对2496例不同健康体检人群的疲劳类型、程度和特征分值与体检指标进行相关分析,探讨疲劳与理化指标之间的相关性；运用SPSS17.0对数据进行回归分析。
结果：
12496例健康体检人群疲劳类型及特征与体检指标回归分析
1.1疲劳类型、程度：经回归分析发现,躯体疲劳、精神疲劳、疲劳后果、疲劳程度因子分值与部分体检指标关系密切,其中①躯体疲劳反应出“淋巴细胞”,回归系数为0.144呈现正相关。②精神疲劳反应出“红细胞平均血红蛋白浓度”,回归系数为-0.072和-0.064,两者回归系数为呈现负相关。③疲劳后果反应出“血小板压积”,回归系数为14.51,并且呈现正相关。④疲劳程度反应出“血小板压积”,回归系数为14.559,并且呈现正相关。
1.2疲劳特征：经回归分析发现,①疲劳对睡眠休息的反应因子分值与“谷丙酶”体检指标关系密切,回归系数为0.114呈现正相关。②疲劳的情境性与“红细胞平均血红蛋白量、血小板计数和谷丙酶”体检指标关系密切,其中红细胞平均血红蛋白量回归系数为-0.529为负相关,血小板计数、谷丙酶回归系数为0.024及0.091呈正相关。
2不同健康状态的疲劳特点与体检指标回归分析
2.1准健康人群疲劳类型、程度及特征与体检指标回归分析
2.1.1疲劳类型、程度：准健康人群①躯体疲劳与“低压、体重和总胆固醇”体检指标关系密切,其中体重回归系数为-0.642呈负相关,低压、总胆固醇回归系数为1.102和5.246呈正相关。②疲劳后果与“血糖”体检指标关系密切,回归系数为6.28呈正相关。③疲劳程度与“嗜酸性粒细胞百分比”体检指标关系密切,回归系数为2.423呈正相关。
2.1.2疲劳特征：经回归分析发现,准健康人群①疲劳对睡眠休息的反应与“嗜碱性粒细胞数量”体检指标关系密切,回归系数为39.177呈正相关。②疲劳的情境性与“红细胞体积分布宽度”体检指标关系密切,回归系数为-10.781呈负相关。
2.2症状亚健康人群疲劳类型、程度及特征与体检指标回归分析
症状亚健康人群在躯体疲劳、精神疲劳、疲劳程度分值筛选出与体检指标关系密切的指标,其中①躯体疲劳与“红细胞平均血红蛋白浓度”体检指标关系密切,回归系数为-0.38呈负相关。②精神疲劳与“血小板体积分布宽度和红细胞平均血红蛋白浓度”体检指标关系密切,回归系数为-0.245及-0.242两者均呈负相关。③疲劳程度与“血小板体积分布宽度”,回归系数为-1.214呈负相关；而疲劳后果、疲劳对睡眠休息的反应、疲劳的情境性未筛检到关系密切的体检指标。
2.3症状-指标亚健康人群疲劳类型、程度及特征与体检指标回归分析
症状-指标亚健康人群在精神疲劳、疲劳后果、劳疲劳程度总分、疲劳的情境性分值筛选出与体检指标关系密切的指标,其中①精神疲劳与“尿素氮”体检指标关系密切,回归系数为0.438呈正相关。②疲劳后果与“总胆固醇”体检指标关系密切,回归系数为-2.132呈负相关。③疲劳程度与“总胆固醇”,回归系数为-2.259并且现负相关。④疲劳的情境性与“谷丙酶和血小板计数”体检指标关系密切,回归系数为0.176及0.0398呈正相关。
2.4疾病人群疲劳类型、程度及特征与体检指标回归分析
2.5.1疲劳类型、程度：经回归分析发现,疾病人群①躯体疲劳与“血压”体检指标关系密切,其中高压呈现负相关,低压呈现正相关。②精神疲劳与“低压、血红蛋白和红细胞体积分布宽度”体检指标关系密切,其中血红蛋白回归系数为-0.081呈负相关,低压及红细胞体积分布宽度回归系数为0.139和0.085呈现正相关。③疲劳程度总分与“低压”体检指标关系密切,回归系数为0.098呈正相关。
2.5.2疲劳特征：经回归分析发现,疾病人群①疲劳对睡眠休息的反应与“谷丙酶”体检指标关系密切,回归系数为0.057呈正相关。②疲劳的情境性与“pH值和红细胞平均血红蛋白量”体检指标关系密切,回归系数为-2.341及-0.273呈负相关。结论：
12496例健康体检人群疲劳类型及特征与体检指标回归分析
本次调研的健康体检人群淋巴细胞、血小板压积、谷丙酶、血小板计数呈正相关,体检指标越高可能导致躯体疲劳、劳后果表现、疲劳程度、疲劳对睡眠休息的反应、疲劳的情境性分值增高,出现四肢酸软、疲乏无力、身体虚弱、头脑反应迟钝、学习效率减低、休息/睡眠无法缓解疲劳,情绪低落、嘈杂及闷热环境、精神紧张加重疲劳感的表现越明显；而当红细胞平均血红蛋白浓度指标、红细胞压积呈负相关,可能说明指标越高或许可以缓解忘事、头脑反应迟钝、注意力不能集中、思路不清晰的精神疲劳表现及缓解由于情绪低落、嘈杂及闷热环境、精神紧张等,外环境变化及负面情绪导致疲劳感加重的疲劳情境性表现。
2不同健康状态的疲劳特点与体检指标回归分析
2.1准健康人群
准健康人群的总胆固醇、血糖、嗜酸性粒细胞百分比、嗜碱性粒细胞数量、体检指标越高可能导致躯体疲劳、疲劳后果、疲劳程度、疲劳对睡眠休息的反应分值越高,表现出四肢酸软、疲乏无力、身体虚弱、头脑反应迟钝、学习效率减低、休息/睡眠无法缓解疲劳等,出现疲劳感加重的表现越明显；而当体重、红细胞体积分布宽度指标越低,躯体疲劳及疲劳情境性的疲劳表现越轻,
2.2症状亚健康人群
症状亚健康人群的红细胞平均血红蛋白浓度、血小板体积分布宽度和红细胞平均血红蛋白浓度体检指标越低,可能导致躯体疲劳、精神疲劳、疲劳程度分值越高,表现出四肢酸软、疲乏无力、身体虚弱、注意力不能集中、思路不清晰、等出现疲劳感加重的表现越明显。
2.3症状-指标亚健康人群
症状-指标亚健康人群的尿素氮、谷丙酶、血小板计数体检指标越高,可能导致精神疲劳、疲劳的情境性分值越高,表现出注意力不能集中、思路不清晰、在情绪低落、嘈杂及闷热环境、精神紧张、外环境的变化及负面情绪等,疲劳感加重表现越明显；而当总胆固醇体检指标越低,疲劳后果、疲劳程度的疲劳表现越不明显。
2.4疾病人群
疾病人群的血压、红细胞体积分布宽度、谷丙酶体检指标越高,可能导致躯体疲劳、精神疲劳、疲劳程度、疲劳对睡眠休息的反应分值越高,表现出四肢酸软、疲乏无力、身体虚弱、注意力不能集中、思路不清晰、休息／睡眠无法缓解疲劳等出现疲劳感加重的表现越明显；而当血红蛋白、pH值和红细胞平均血红蛋白量指标越高精神疲劳、疲劳的情境性疲劳表现越轻。
As a symptom of subjective feeling, fatigue is complex reflect of physiological, psychological and pathological phenomena of weaken or loss of physical or mental energy. Therefore, fatigue can be found in healthy people. And also can be used as a symptom in many physical and mental diseases. The study found that there still exist a sub-health state between health and disease in addition to health and disease in the mid1980s. In recent years, with the competition pressure increasing and the diversity of living environment changing, the people in the state of sub-health have the trend of increasing year by year. Fatigue is the common performance of the sub-health status. In general, the whole life process of the human body is mutual transformation of health, sub-health and disease three states. No matter what kind of state may appear a certain degree of fatigue. Therefore, fatigue is the very common phenomenon or symptom. It has larger influence on people's daily life, especially the fatigue of sub-health state. But at present our country still lack of systematic research and the corresponding data reports about fatigue incidence and fatigue characteristics of different people.
The basic characteristics of traditional Chinese medicine are the overall concept and differentiation and treatment. There are many advantages in TCM intervention of fatigue, especially for which mechanism is not clear. Therefore, the investigation of sub-fatigue in the crowd of medical examinations from medical center were carried out. The fatigue status of the crowd of health,sub-health and different disease were analyzed.The relationship between medical examination indexes and the fatigue characteristics were discussed. This study may provide the basis for further study about incidence, characteristics of fatigue type,possible occurrence mechanism and traditional Chinese medicine intervention study of fatigue.
Research one:the incidence of fatigue symptoms among the crowd of healthy medical examinations.
Objective:
Through the investigation of fatigue state in the crowd of healthy medical examinations, the incidence of the fatigue symptom in the crowd of health, sub-health and the disease were analyzed.
Methods:
Through the method of field investigation, common international fatigue scale (FS-14) was applied. The investigation of fatigue in the crowd of medical examination were carried out in Beijing xiaotangshan hospital medical center from March2011to March2012. The crowd were divided into three groups of health, sub-health and illness in accordance with fatigue symptom judgment standard (FS or3) this research protocol, criteria of subordinate state in the health check-up crowd, process and medical report from physical examination center. The occurrence of fatigue in all kinds of the crowd were analyzed. The database was established by using Epdata3.1software. The related physical examination data was input. All kinds of descriptive analysis were done by using SPSS17.0.
Results:
1General healthy people and healthy state distribution
1.12823cases of healthy people healthy state.
Meet the surveyed population inclusion criteria, a total of2823cases, Age range19to60years old, with an average age of39.84±9.51years; males and1398(49.5%), the average age of40.23±9.72years old, women,1425cases (50.5%), with an average age of39.92±9.80years.
2823cases of population, belong to the healthy population,204cases (7.23%), Standard healthy population of13patients (0.46%), the quasi-healthy population of191cases (6.77%); Is a sub-health population in1053cases (37.30%), symptomatic sub-health population,324cases (11.48%), indicative of sub-health population of the52cases (1.84%), symptoms-indicators the sexual subhealth crowd of677cases (23.98%); belongs disease crowd of1,566cases (55.47%), which appear frequency among the top ten by high blood pressure, chronic pharyngitis, fatty liver (more moderate), hyperplasia (more moderate), Hypertension, chronic pharyngitis, fatty liver (more moderate), hyperplasia (more moderate), high cholesterol, uterine fibroids, diabetes, allergic rhinitis, thyroid nodules, cervical spondylosis.
2. Fatigue incidence of different health status examination crowd
2.1Healthy population of fatigue
204healthy people (including the standard of health and prospective health crowd),167cases of fatigue and fatigue incidence of81.86%.
2.2Fatigue occurrence of sub-health population
1053cases of sub-health population(Include Symptomatic sub-health、indicator sub-health, symptoms-indicators sub-health),881cases exist fatigue, Fatigue incidence of83.67%;The symptoms of sub-health fatigue incidence89.50%, the symptoms-indicative sub-health fatigue incidence of87.30%.
2.3The disease populations fatigue happens
1566cases of disease groups (including all populations of suffering from various diseases),1448cases exist where fatigue, fatigue incidence92.46%.
The number of cases and the incidence of the top10diseases in patients with fatigue order, Hypertension in480cases (93.00%), fatty liver,277cases (92.00%), the chronic pharyngitis 272cases (89.77%), high cholesterol,262cases (92.58%), breast hyperplasia in353cases (92.88%),150cases of uterine fibroids (88.34%), diabetes in148cases (91.92%), allergic rhinitis,100cases (90.91%), thyroid nodules,89cases (89.90%), cervical spondylosis75cases (96.15%),Fatigue of patients with cervical spondylosis incidence was highest the fatigue between disease incidence was no statistical difference.
Conclusion:
According to the research methods used in this study is preliminary draw:
Examination of the different health status of populations, have fatigue symptoms occur, its incidence descending order of diseases, sub-health and the health of populations, reflecting extensive fatigue.
二、Research two:research on fatigue characteristics of different crowds of healthy medical examination Objective:
To evaluate of fatigue type, degree and characteristics among the crowd of health, sub health, disease
Method:Through the on-site survey methods, the use of a common international fatigue scale (FS-14) and self-developed research group fatigue self-rating scale (FSAS), Healthy people to Beijing xiaotangshan Hospital Medical Center from March2011to March2012examination, and to accept voluntary survey fatigue status of the investigation; Criteria (Annex1) in accordance with the healthy population belongs to the state of the study and draw the physical examination population health, sub-health and disease three categories, analysis, fatigue type, extent and characteristics of all types of people; to use Epdata3.1software to establish a database entry surveyed the crowd fatigue and physical examination data; use SPSS17.0various analysis.
Result:
The Institute's analysis of the object from" Research a "Physical examination population selected with fatigue(FS-14≥3)2496cases of people, male and1,284cases (51.44%), with an average age of40.40±9.70, and1212cases of women (48.56%), the average age to39.67±9.46; belong to the health status of167patients (6.69%) prevail healthy) belongs to the sub-health state,881cases (35.30%), which symptomatic sub-health the290cases (11.62%), symptoms-indicator sub-health crowd of591cases (23.68%); belongs disease crowd of1448cases (58.01%).
1Based on the fatigue characteristics of the fatigue scale (FS-14)
The three groups of health, sub-health, diseases fatigue score, the score of physical fatigue and mental fatigue scores were4.86±1.96,2.57±1.65,2.28±1.39;5.88±3.13,3.53± 2.25,2.35±1.71;5.52±2.78,3.35±2.11,2.17±1.59. The two physical fatigue scores and fatigue illness crowd highest among comparison.
1.1Fatigue characteristics of the healthy population (quasi-healthy people)
167cases of quasi-health crowd, Male and female body, brain and overall fatigue scores were2.60±1.63VS2.55±1.68.2.23±1.46VS2.34±1.30,4.83±1.94VS4.89±1.99, Higher in women than in men, but no significant difference; Fatigue scores from different ages,41to50-year-old age body, brain and overall fatigue scores the highest body of51to60years of age and overall fatigue scores lowest, to31～40-year-old mental ages fatigue lowest score, No significant difference between different ages (P>0.05); Distribution from the entry of the Fatigue Scale, mental fatigue"Did you feel the memory decline it?", The frequency of occurrence of the highest (60.37%), physical fatigue in"Do you feel the need to get more rest?" The frequency of occurrence of the highest (47.56%).
1.2The fatigue characteristics of the sub-health population
The881cases subhealth population (including symptoms of sub-health and symptoms-indicators of sub-health population), physical fatigue and general fatigue score of41to50-year-old age group is the highest, the lowest ages of51to60years old; mental fatiguethe highest score the ages of21to30-year-old,41to50years old age minimum; From the scale of entry distribution, in symptomatic subhealth crowd in "Do you feel the need to get more rest?" The frequency of occurrence as the highest(73.10%);Symptoms-indicative of sub-health population"Are you bothered by fatigue it?" The frequency of occurrence as the highest(53.64%).
The symptoms of sub-health population's physical, mental, and overall fatigue scores were higher than the symptoms-indicative of sub-health population, fatigue scores were4.37±2.14VS3.14±2.14N2.60±1.86VS2.20±1.61、6.94±3.22VS5.34±2.88, And significant difference (P<00.05)。
1.3The disease populations fatigue characteristics
1448cases of the disease population, male and female body and overall fatigue scores were3.31±2.10VS3.39±2.12.5.49±2.81VS5.55±2.76, Women than men, but no significant difference; Physical fatigue and general fatigue score of31to40-year-old age group is the highest, the lowest ages of51to60years old; ages of21to30-year-old was the highest score of mental fatigue, ages41to50years oldminimum; distribution from scale entry "Do you feel the need to get more rest?" Occurs at a frequency up to57.2%.
1.4Fatigue characteristics of common diseases
Frequency of occurrence of the top10of the disease, according to the fatigue score in descending order of the following order:
①physical fatigue:Cervical disease (3.79±2.43), high cholesterol(3.45±2.16) thyroid nodules (3.43±1.88), breast hyperplasia (3.41±2.17), diabetes (3.39±2.25) Allergic rhinitis (3.38±2.11), Hypertension(3.30±2.07), uterine fibroids (3.27±2.04) fatty liver (3.23±2.11), Chronic pharyngitis (3.21±2.12)
②Mental fatigue:Diabetes (2.31±1.67), Cervical disease (2.31±1.75), Chronic pharyngitis (2.28±1.62)、Breast hyperplasia (2.23±1.70)、Allergic rhinitis (2.19±1.67)、Uterine fibroids (2.18±1.66)、Hypertension (2.14±1.56)、thyroid nodules (2.13±1.72)、high cholesterol (2.11±1.57)、fatty liver (2.11±1.53)。
③Overall fatigue:Cervical disease (6.09±3.22)、diabetes (5.70±3.20)、breast hyperplasia (5.64±2.81)、high blood cholestero (5.56±2.81)、 thyroid nodules (5.56±2.85). allergic rhinitis (5.55±3.02)、chronic pharyngitis (5.49±2.83)、 uterine fibroids (5.47±2.80)、hypertension (5.44±2.76)、 fatty liver (5.33±2.70)
The distribution of specific entries, Hypertension, fatty liver, chronic pharyngitis, high cholesterol, diabetes, allergic rhinitis, thyroid nodules, cervical patients"Do you feel the need to get more rest?" the frequency of occurrence as the highest, Mental fatigue type are"Did you feel the memory decline it?" the frequency of occurrence is the highest.
Further analysis found that hypertension、diabetes、fatty liver:①physical examination, abnormal blood pressure in hypertensive patients3fatigue scores were higher than normal blood pressure in hypertensive patients;②physical examination, abnormal blood glucose levels in diabetic patients3fatigue scores were higher than normal blood sugar levels of diabetic patients, including physical fatigue score has a statistically significant difference between the two (P<0.05);③Fatty liver in patients with moderate to severe mental and overall fatigue scores were higher than in patients with moderate fatty liver;④Hypertension and diabetes, and high cholesterol patients physical, mental and overall fatigue scores were higher than mere hypertensive patients, including mental fatigue is a significant difference between the two groups;㏑elatively simple fatigue scores of the three groups of high blood pressure, high cholesterol and diabetes, physical fatigue scores for the highest mental fatigue and overall fatigue scores in patients with high cholesterol diabetes patients the highest.
2Fatigue characteristics based fatigue self-rating scale (FSAS)
Three groups of healthy (Quasi health), sub-health, diseases "physical fatigue" factor scores were27.67±22.21、30.81±23.31、33.86±23.62;"Fatigue on sleep the rest of the reaction" Factor scores, respectively29.79±27.21、26.08±26.35,28.51±27.13, two factor scores were significantly different in the three groups(P<0.05)。
2.1Healthy population fatigue characteristics of the (quasi-healthy people)
Gender fatigue characteristics of scores of female physical fatigue than men, mental fatigue, fatigue consequences, the degree of fatigue score, the rest of the reaction of fatigue on sleep, fatigue situational five factor scores men than women.
(1) The fatigue the type and extent of
167cases of fatigue type of quasi-healthy people score the same degree of fatigue to mild,56.71%physical fatigue, mental fatigue away from64.02%to63.41%, fatigue consequences.
(2) Characteristics of fatigue
Quasi-healthy people in the rest/sleep, unable to relieve fatigue response,29.07%of the people after a rest or sleep, fatigue can be alleviated; fatigue situational, only0.37%of the people is not obvious.
2.2Fatigue characteristics of sub-health population
881cases of sub-health population, male and female gender for the main types of physical fatigue score was30.47±23.26,31.16±23.38women than men, but no significant difference; between ages31to40years oldphysical fatigue, mental fatigue, fatigue consequences for the highest score,41to50-year-old mental fatigue, the highest score of the degree of fatigue, the score was no statistical difference between the highest score of51to60-year-old situational fatigue, different ages (P>0.05).
(1) The fatigue the type and extent of
The symptomatic sub-health and symptoms-indicators of sub-health fatigue type are the types of physical fatigue, the score of31.37±23.87,30.36±23.74, and there is a statistically significant difference, the symptomatic sub-health physical fatigue most obvious.
(2) Characteristics of fatigue
Above symptoms of sub-health symptoms-indicator sub-health in the reaction can not alleviate the fatigue of rest/sleep,36.58%of the people think that obvious; only31.09%of the people can alleviate the symptoms of fatigue performance; fatigue situational analysis found that the degree of mainly to more obvious symptoms of sub-health above symptoms-indicators sub-health40.64%40.85%.
2.3Disease populations fatigue characteristics.
1448cases of the disease population, male and female gender for the main types of physical fatigue score of33.64±32.19,33.67±32.25; higher in women than in men, but no significant difference; different between the ages of31to50years oldbetween fatigue type, extent and characteristics of the highest score, score no statistically significant difference (p>0.05).
(1) The fatigue the type and extent of
Disease populations belong to the physical fatigue score of33.86±23.62degree moderate physical fatigue moderate accounted for61.17%, the mental fatigue moderate (68.42%), the fatigue consequences moderate accounted for68.79%of overall fatigue moderate accounted for71.15%
(2) Characteristics of fatigue
Disease population, only29.07%of the people think, rest/sleep can ease the symptoms of fatigue; fatigue situational only0.37%of people think that is not obvious.
2.4Fatigue characteristics of the populations of the common diseases
The survey appears most long to see the10diseases were Hypertension, breast hyperplasia, fatty liver, chronic pharyngitis, high cholesterol, uterine fibroids, diabetes, allergic rhinitis, thyroid nodules, cervical spondylosis.
①Physical fatigue scores in descending order, cervical spondylosis> thyroid nodules>allergic rhinitis>chronic pharyngitis>high cholesterol> hypertension> breast hyperplasia> fatty liver> uterine fibroids> Diabetes.
②Mental fatigue scores, high to low for High cholestero> allergic rhinitis> hyperplasia>thyroid nodules> fatty liver>cervical spondylosis> hypertension>chronic pharyngitis> diabetes>uterine fibroids.
③Rest/sleep reaction to low Cervical disease> fatty liver> diabetes> high cholesterol>chronic pharyngitis> hypertension> thyroid nodules>allergic rhinitis> uterine fibroids>breast hyperplasia.
④Fatigue situational lowest is Cervical disease>high cholesterol> chronic pharyngitis>diabetes> hypertension> fatty liver> allergic rhinitis>hyperplasia>uterine fibroids> thyroid nodules.
⑤Fypertension blood pressure in patients with abnormal fatigue consequences and the degree of fatigue scores were higher than normal blood pressure, and both have a statistically significant difference (P<0.05); diabetes blood glucose in patients with abnormal fatigue situational score to56.92±25.11highnormal, with a significant difference (P<0.05).
Conclusion:
1Based on the fatigue characteristics of the fatigue scale (FS-14)
1.1Health (quasi-health) crowd fatigue characteristics:41to50-year-old age people prone to fatigue troubled, need more rest, memory loss and other performance, while the older body and overall fatigue will decrease.
1.2Sub-health population fatigue characteristics:male body fatigue than women obviously, is prone to need more rest and fatigue plagued discomfort performance, especially in sub-health population symptomatic than the symptoms-indicative of sub-health population prone to discomfort symptoms, resulting infatigue worse.
1.3Disease populations fatigue characteristics:the fatigue characteristics of women than men is more obvious, especially in the31to40-year-old, and need more than the rest of the body prone to fatigue performance.
1.4Common diseases fatigue characteristics:cervical spondylosis and physical examination, blood pressure, abnormal blood pressure, blood sugar of diabetics occurs when fatigue distress, need more rest, not enough energy, muscle strength decreases when hypertensive patients with diabetes and highlipids variety of diseases, fatigue symptoms are aggravated and simple hypertension, high cholesterol, diabetes three diseases are again more obvious symptoms of high blood cholesterol fatigue; severe fatty liver patients, inattention appears, the mind is not clear, memorydecline, mental fatigue performance significantly.
2Fatigue self-rating scale (FSAS)-based study of
2.1Comparison of health, sub-health, disease populations fatigue self-rating scale factor
scores
Healthy population Fatigue Scale (FSAS) fatigue characteristics①physical fatigue score low disease> sub-health> quasi health rigor exhaustion, tired consciously debilitating diseases the performance crowdsignificantly, followed by sub-health and prospective health.②fatigue reaction to rest on sleep scores in descending order of disease> Health> sub-health, disease populations due to the presence of their disease, and lead to the emergence of symptoms of fatigue can not be relieved by rest/sleep, can be seen symptoms of fatigue nothing to do with the rest/sleep, but related to the disease itself.
2.2Self-rating scale fatigue characteristics of the three groups of fatigue
2.2.1Fatigue types, extent and characteristics of quasi-healthy people
Quasi-healthy people to physical fatigue were mild, extent, prone to rigor, fatigue, weakness, mind unresponsive, depressed and tired of things do not want to do it anymore, and reduce the learning efficiency performance performance; anddepression, noisy, hot and stuffy environment, mental stress or negative emotions, such as the impact of easy fatigue symptoms get worse.
2.2.2Sub-health population fatigue types, extent and characteristics
Symptoms the sexual sub-health group than the symptoms-indicators of sub-health group prone, rigor, fatigue, weakness, frail feeling, lack of concentration, forgetfulness, slow to respond to phenomena; led to depression and do not want to get bored of thin gsto do so, reduce the efficiency of learning the consequences of fatigue performance; symptoms indicators of sub-health group that fatigue is not relieved by rest or sleep, obviously; symptoms of sub-health group because of the depression, the noisy and humid environments, nervous and external environ mentthe changes and negative emotions are likely to aggravate the symptoms. Positive mood and a good environment for an active role in the two sets of sub-health population to relieve fatigue.
2.2.3The disease populations fatigue type, extent and characteristics
Disease crowd to physical fatigue, and half the time there will be a rigor exhaustion, the performance of the limbs, muscle weakness, and lead to learning efficiency to reduce the consequences of fatigue performance; disease crowd fatigue has obvious situational specificity due to diseases caused by the body and spiritthe effect of pressure, so most of the people engaged in pleasant things can alleviate the symptoms of fatigue, and half of the people think that fatigue aggravated depressed or irritable when.
2.2.4Fatigue types, extent and characteristics of the common diseases
The cervical spondylosis prone rigor, fatigue, weakness, limbs, muscle weakness, still unable to ease the symptoms of fatigue after a rest/sleep, and depressed or irritable when fatigue aggravated; hyperlipidemia in patients prone to forget things unresponsive mind, learning efficiencyreduced.
Abnormal levels of blood pressure in patients with hypertension,May aggravate depression, tired of things do not want to do it anymore, and reduce the learning efficiency performance; abnormal blood sugar levels of diabetic patients, it may be easier because of the depression, noisy and humid environments, nervous, changes in the external environment and more sensitive to negative emotions lead to aggravation of fatigue; hypertension and diabetes and high cholesterol, rest/sleep does not alleviate the symptoms of fatigue and depression, noisy, hot and stuffy environment, nervous, changes in the external environment and the negative emotions the impact of further aggravation of the symptoms of fatigue.
Research three:
research on occurrence and symptom characteristics of fatigue and correlation analysis of the four seasons in the different crowds of healthy medical examination
Objective:
To explore the incidence rate and type,degree and characteristics of fatigue in different crowds of medical examination in different seasons.
Method:
Basis 《Twenty-four solar terms solution》 Start of the solar terms in four seasons in one year four established "(beginning of spring, beginning of summer and beginning of autumn, the beginning of winter) as the criteria for the classification of the four seasons (3.21to6.21in spring and6.22to9.22for the summer,9.23to12.21Fall12.22to3.20for wintcrclassified at the Four Seasons),2823cases of healthy people surveyed on the Beijing Xiaotangshan health examination center, analysis and comparison of the differences in the incidence and characteristics of the different seasons of the survey population fatigue, to explore the relationship between fatigue and seasons; use SPSS17.0kinds of descriptive analysis.
Results:
1Four Seasons in2823cases of the general healthy population
Age range of19to60years old, a spring average age of40.61±9.55years, a total of770cases were male and406(29.04%) and364females (25.54%); summer average age of38.19Q8.90years, a total of575cases were male296(21.17%) and279females (19.58%); fall an average age of40.04±9.739years, a total of1185cases were male and553(39.56%) and632females (44.35%); winter average age of40.20±9.28years of age, a total of293cases were male and143(10.23%) and150females (10.53%) in spring oldest, youngest summer.
2Distribution healthy crowd of fatigue at the Four Seasons
2.1Different health status in the occurrence of the Four Seasons fatigue
Healthy people in the winter fatigue happens is up to90.91%, the sub-health population occurred in the summer of fatigue up to89.57%, disease crowd highest in winter and accounted for92.99percent, the lowest incidence of sub-health, disease, the two groups are spring fatigue of the crowd,two groups in different seasons fatigue happens there is a statistically significant difference (P<0.05).
2.2Four Seasons the fatigue scales FS-14fatigue characteristics
2.2.1The fatigue characteristics of the three groups
①healthy people physical fatigue mental fatigue scores were higher than the highest score in the autumn.②sub-health population physical, mental and general fatigue there is a statistically significant difference (P<0.05).③Disease populations in different seasons, physical fatigue in the summer the highest mental fatigue and general fatigue was highest in autumn, Four Seasons physical fatigue than mental fatigue, fatigue characteristics there is a statistically significant difference (P<0.05).
2.2.2Fatigue characteristics of the different seasons of the populations of the common diseases
①hypertensive patients found fatigue scores in different seasons, and physical fatigue in the spring when the lowest maximum winter, mental fatigue highest in winter and lowest in spring, and there is a significant difference (P<0.05).②breast hyperplasia, high cholesterol, diabetes, cervical spondylosis, fatigue scores in different seasons found that physical fatigue is highest in summer and lowest in winter, and there is a significant difference (P<0.05)③ patients with allergic rhinitis fatigue scores in different seasons found that mental fatigue is highest in the autumn, and there is a significant difference (P<0.05).
2.3Fatigue characteristics of the different seasons based on fatigue self-rating scale (FSAS)
2.3.1Fatigue type and extent of the group at the Four Seasons:①physical fatigue: physical fatigue factor for health and sub-health population score highest in autumn; the healthy populations summer the lowest score, health groups lowest score in winter; types of labor in the two populations seasons there is a statistically significant difference (P <0.05);The degree of physical fatigue, the health and subhealth physical fatigue for mild autumn highest disease population and physical fatigue as moderate in autumn, three groups there is a significant difference (P<0.05).②mental fatigue:health, sub-health population mental fatigue factor scores was statistically significant (P<0.05), the two groups are the highest in autumn, the degree of mental fatigue to mild.③fatigue consequences:health consequences of sub-health population fatigue factor scores was statistically significant (P <0.05), are highest in autumn, a mild degree of fatigue consequences diseases and sub-health population statistically significant (P<0.05),(4) the degree of fatigue Score:health, sub-health population the degree of fatigue scores was statistically significant (P<0.05) in the factor scores are highest in autumn, health and sub-health population in the degree of fatigue to mild main disease populations to moderate.
2.3.2Fatigue characteristics of each group at the Four Seasons:①the reaction of the fatigue of the rest/sleep:health, sub-health population fatigue response to rest/sleep factor scores was statistically significant (P<0.05), are the highest in autumn. The②fatigue situational:health, disease, health groups fatigue situational factor scores was statistically significant (P<0.05), healthy population highest in the winter, disease, health groups, the highest in the fall.
2.3.3Occurrence of fatigue symptoms of common diseases at the Four Seasons:①hypertensive patients with fatigue scores in different seasons, fatigue types belong to body fatigue, the highest in the fall, fatigue consequences of fatigue on sleep the rest of the reaction, fatigue situational significant difference (P<0.05).②chronic pharyngitis patients found that fatigue type belonging to physical fatigue fatigue scores in the different seasons, and in the fall when the highest physical fatigue, mental fatigue, fatigue consequences, the degree of fatigue total score of fatigue on sleep the rest of the reaction a significant difference (P<0.05).(3)in patients with breast hyperplasia fatigue scores in the different seasons of spring and autumn obvious physical fatigue, mental fatigue of the summer and winter fatigue situational significant difference (P<0.05).④high blood cholesterol in patients with fatigue scores in the different seasons, only fatigue the scenario was no significant difference (P>0.05).⑤diabetes fatigue scores in different seasons fatigue type of mental fatigue, fatigue consequences, the degree of fatigue scores statistically significant difference (P<0.05).⑥patients with allergic rhinitis found fatigue scores in different seasons, spring and winter mainly physical fatigue, mental fatigue in the summer and fall mainly fatigue situational significant difference (P<0.05).
Conclusion:
1Distribution healthy crowd of fatigue at the Four Seasons
Predilection sub-health population in the summer when the most obvious symptoms of fatigue, disease crowd in the winter the most obvious symptoms of fatigue; women's spring and summer the most obvious symptoms of fatigue, people in the41to60age group in the spring when the fatigue symptoms most prominentThe fatigue symptoms eased autumn.
2Fatigue Scale (FS-14) in the Four Seasons fatigue characteristics
2.1The fatigue characteristics of the three groups:①the healthy population plagued fatigue, rest feel powerless, not enough energy and overall fatigue gradually increased as the seasons change, will be eased in the winter. The②subhealth crowd symptoms of fatigue with the seasons and relieve fatigue symptoms lightest in the fall, fatigue plagued by symptoms of sub-health population in the summer, need more rest feel powerless, energy is not enough body, fatigue, general fatigue performance than obvious symptoms-sub-health population. The③disease groups in summer plagued fatigue, need more rest feel powerless, energy is not enough physical fatigue performance of the most obvious; inability to concentrate in the fall when the mind is not clear, memory decline, overall fatigue is the most obvious.
2.2Common characteristics of the different seasons of the disease population fatigue:①the hypertensive patients plagued fatigue, you need plenty of rest to feel powerless, energy is not enough performance, most obvious in the spring; winter was attention difficulties, memory loss, loss of interest in the habit of doing things the most obvious.②breast hyperplasia, high cholesterol, diabetes, cervical spondylosis easy in the summer when fatigue plagued need more rest feel powerless, energy is not enough performance③patients with allergic rhinitis easy in the fall to attention difficulties, the mind is not clear, memory loss, the most obvious manifestations of the habit of doing things lose interest.
3Fatigue characteristics of the different seasons based on fatigue self-rating scale (FSAS)
3.1Group at the Four Seasons in the type and extent of fatigue:①physical fatigue:the three groups in the fall when rigor is weak, tired, weak performance of the degree of the heaviest, the fatigue symptoms lightest winter.②mental fatigue:health, health groups appear inattention, unresponsive, forget things, and other symptoms tended to increase in the summer to autumn mental fatigue, mental fatigue autumn to winter on a downward trend, while the disease crowd from summer to winter there are a growing trend.①Fatigue consequences: health and sub-health population in the summer to the fall, appear depressed, tired of things do not want to do it anymore, and reduce the learning efficiency performance tended to increase, a downward trend in the autumn to winter fatigue consequences, disease groups from
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