振动训练对大鼠骨骼肌运动能力的影响及其机制探讨
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摘要
【目的】研究不同模式振动训练对大鼠运动能力的影响,探讨振动训练提高运动能力的细胞分子生物学机制。【方法】以42只雄性SD大鼠为实验对象,建立不同振动训练模型,评价各实验组大鼠骨骼肌运动能力变化,测试肌组织细胞水平、肌肉肌酸激酶(CK)、肌细胞机械生长因子(Mechano growth factor, MGF)表达水平。通过肌卫星细胞培养,测试机械刺激对卫星细胞增殖和蛋白含量影响。【结果】中频率长时间振动组(ML)大鼠游泳成绩和最大抓力均显著高于对照组(CC),且该组的腓肠肌相对质量、肌纤维横截面积(CSA)、CK和MGF mRNA的表达均显著增加(P < 0.05);卫星细胞培养结果显示,机械张力刺激后,卫星细胞增殖能力均大于对照组(p< 0.01),且15%拉伸刺激增殖效果最佳。【结论】振动训练刺激可能通过激活卫星细胞增殖和肌细胞机械生长因子的表达、促进肌纤维选择性肥大、提高骨骼肌细胞代谢酶CK活性等途径提高肌肉的运动能力。
Objective: The present study was designed to examine the effects of different vibration trainings on the exercise capacity, and further explore the underlying mechanism of cellular and molecular biology. Methods: 42 male Sprague-Dawley rats were used to establish different vibration training models. Exercise capacity in rat skeletal muscle was evaluated, the chemical levels in muscle tissue, muscle creatine kinase (CK) and myocytes Mechano growth factor (MGF) expression levels were tested. Proliferation and protein content of satellite stimulated by vibration were detected through muscle myo-satellite cell culture experiments. Results: Compared to the control group(CC), scores of swimming and grasping power in the medium-frequency vibration prolonged group(ML) were significantly improved. In addition, the relative quality of the gastrocnemius muscle, fiber cross-sectional area, CK and MGF mRNA expression was significantly increased in ML group. Cultured quiescent satellite cells were subjected to mechanical stretch in a Flexer Cell System. In response to stretch stimulation, the multiplication ability and protein content in satellite cell were higher than those in the control group. Conclusions: Vibration training may stimulate proliferation of satellite cells and the expression of MGF mRNA, promote muscle hypertrophy and CK enzymes activity, then lead to the enhancement of exercise performance.
Objective: The present study was designed to examine the effects of different vibration trainings on the exercise capacity, and further explore the underlying mechanism of cellular and molecular biology. Methods: 42 male Sprague-Dawley rats were used to establish different vibration training models. Exercise capacity in rat skeletal muscle was evaluated, the chemical levels in muscle tissue, muscle creatine kinase (CK) and myocytes Mechano growth factor (MGF) expression levels were tested. Proliferation and protein content of satellite stimulated by vibration were detected through muscle myo-satellite cell culture experiments. Results: Compared to the control group(CC), scores of swimming and grasping power in the medium-frequency vibration prolonged group(ML) were significantly improved. In addition, the relative quality of the gastrocnemius muscle, fiber cross-sectional area, CK and MGF mRNA expression was significantly increased in ML group. Cultured quiescent satellite cells were subjected to mechanical stretch in a Flexer Cell System. In response to stretch stimulation, the multiplication ability and protein content in satellite cell were higher than those in the control group. Conclusions: Vibration training may stimulate proliferation of satellite cells and the expression of MGF mRNA, promote muscle hypertrophy and CK enzymes activity, then lead to the enhancement of exercise performance.
引文
[1]. Harris CM. Introduction to the handbook. In: Harris CM, editor Shock and vibration handbook. New York: McGraw-Hill,1996:1.1-1.27
[2]. Issurin VB, Tenenbaum G. Acute and residual effects of vibratory stimulation on explosive strength in elite and amateur athletes. J Sports Science, 1999;17: 177-182
[3]. Cardinale M, Lim J. The acute effects of two different whole body vibration frequencies on vertical jump performance. Med. Sport, 2003, 56: 287-292
[4]. Wei Xiaoyan , Peng Chunzheng . A New Method of Muscle Strength Training By Vibrating Platform. the Proceedings of 2004 Pre-Olympic Congress, Vol.1 pp473, 2004, Thessaloniki, Greece.
[5]. 危小焰,彭春政.振动力量训练对肌肉力量的影响研究.体育科研,2004, 25(4): 53-57
[6]. 彭春政,危小焰. 抗负荷力量训练附加全身振动刺激对肌力训练效果的影响.上海体育学院学报,2003,27(1):70-73
[7]. Jin Luo, Brian McNamara and Kieran Moran. The use of vibration training to enhance muscle strength and power. Sports Med. 2005, 35(1):23-41
[8]. Chakravarthy MV, Davis BS, Booth FW. IGF-I restores satellite cell proliferative potential in immobilized old skeletal muscle. J Appl Physiol, 2000, 89(4):1365-1379
[9]. Vary TC, Kimball SR Effect of sepsis on eIE4E availability in skeletal muscle. Am J Physiol Endocrinol Metab, 2000, 279(5): E1178-84
[10]. Coleman ME, DeMayo F, Yin KC, et al. Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice. J Biol Chem, 1995, 270(20):12109-16.
[11]. Carson JA, Yan Z, Booth FW, et al. Regulation of skeletal alpha-actin promoter in young chickens during hypertrophy caused by stretch overload. Am J Physiol. 1995, 268(4):C918-24
[12]. Mayhew TP, Rothstein JM, Finucane SD, et al. Muscular adaptation to concentric and eccentric exercise at equal power levels. Med Sci Sports Exerc 1995, 27(6): 868–873
[13]. Goldspink G. Mechanical signals, IGF-I gene splicing, and muscle adaptation. Physiology, 2005, 20:232~238
[14]. Goldspink G. Research on mechano growth factor: its potential for optimising physical training as well as misuse in doping[J]. British J Sports Med, 2005, 39:787-788
[15]. Goldspink G, Yang S Y, Skarli M, et al. Local growth regulation is associated with an isoform of IGF-Ⅰ that is expressed in normal muscles but not in dystrophic muscles[J]. J Physiol, 1996, 495:162-168
[16]. Yang S Y, Alnaqeeb M, Simpson H, et al. Cloning and characterization of an IGF-Ⅰ isoform expressed in skeletal muscle subjected to stetch[J]. J muscle Res Cell Motil, 1996, 17:487-495
[17]. Yang S Y, Goldspink G. Different roles of the IGF-ⅠEc peptide (MGF) and mature IGF-Ⅰ in myoblast proliferation and differentiation[J]. FEBS Lett, 2002, 522: 156-160
[18]. Hameed M, Lange K H, Andersen J L, et al. The effect of recombinant human growth hormone and resistance training on IGF-Ⅰ mRNA expression in themuscles of elderly men[J]. J Physiol, 2004, 555, 231-240
[19]. Issurin VB. Vibrations and their applications in sport. J Sports Med Phys Fitness. 2005;45(3):324-336
[20]. Issurin VB, Liebermann DG, Tenenbaum G. Effect of vibratory stimulation training on maximal force and flexibility. J Sports Sci. 1994;12(6):561-566
[21]. McBride JM, Porcari JP, Scheunke MD. Effect of vibration during fatiguing resistance exercise on subsequent muscle activity during maximal voluntary isometric contractions. J Strength Cond Res. 2004, 18(4):777-781
[22]. Cardinale M, Wakeling J. Whole body vibration exercise: are vibrations good for you?. Br J Sports Med. 2005, 39(9):585-589
[23]. Rittweger J, Ehrig J, Just K, et al. Oxygen uptake in whole-body vibration exercise: influence of vibration frequency, amplitude, and external load. Int J Sports Med 2002;23:428–432
[24]. Oxlund B S, Qrtoft G, Andreassen T T, et al. Low-intensity, high-frequency vibration appears to prevent the decrease in strength of the femur and tibia associated with ovariectomy of adult rats. Bone. 2003, 32(1):69 ~77
[25]. Luo J, McNamara B, Moran K. The use of vibration training to enhance muscle strength and power. Sports medicine 2005; 35(1) : 23~41
[26]. Kirsten Legerlotz, Peter Schjerling, Henning Langberg, et al. The effect of running, strength and vibration strength training on the mechanical, morphological and biochemical properties of the Achilles tendon in rats. J Appl Physiol, 2007, 102(2):564~572
[27]. 张爱芳,主编.实用运动生物化学[M], 北京: 北京体育大学出版社, 2005
[28]. Bosco C, Colli R, Introini E, et al. Adaptive responses of human skeletal muscle to vibration exposure. Clin Physiol 1999;19:183~187
[29]. Bosco C, Iacovelli M, Tsarpela O, et al. Hormonal responses to whole-body vibration in men. Eur J Appl Physiol 2000;81: 449 ~ 454.
[30]. Delecluse,Roelants M, Verschueren N. Strength Increase after Whole-Body Vibration Compared with Resistance Training. Med. Sci. Sports Exerc., 2003, 35(6):1033~ 1041
[31]. De Luca A, Pierno S, Liantonio A, et al. Enhnced dystrophic progression in mdx mice by exercise and beneficial effects of taurine and insulin-like growthfactor-1. J Pharmacol Exp Ther. 2003,304:453~463
[32]. Mulder ER, Stegeman DF, Gerrits KH, et al. Strength, size and activation of knee extensors followed during 8 weeks of horizontal bed rest and the influence of a countermeasure. Eur J Appl Physiol. 2006;97(6):706-15
[33]. Von Gierke HE,Goldman DE. Effects of shock and vibration on man.In:Harris CM,editor.Shock and vibration handbook.New York:McGraw-Hill,1998:44-1-44-58
[34]. Terada Shin, Toshiko Yokozeki, Kentaro Kawanaka, et al. Effects of high-intensity swimming training on GLUT-4 and glucose transport activity in rat skeletal muscle. J Appl Physiol, 2001,90: 2019–202
[1]. Akira Okada, Mari Nari, Makoto Ariizumi. Experimental studies on the effects of vibration and noise sympathetic nerve activity in skin[J]. Europe Journal of Applied Physiology, 1991,(62):324-331
[2]. Von Gierke HE,Goldman DE.Effects of shock and vibration on man.In:Harris CM,editor.Shock and vibration handbook.New York:McGraw-Hill,1998:44-1-44-58
[3]. C.-C.Mao, K.C.McGill and L.J. Dorfan. Muscle vibration facilitates orferly recruitment of motor units[J].Electromyogr.Clinical. Neurophysiology, 1990, (30):245-252
[4]. Fox, E.L. and Hatthews. D.K. The Physiological Basis of Physical Education and Athletics Philadelphia[J].PA:Sau Nders College Publishers,1981, (49):123-128
[5]. Seumas McCroskery, et al . Myostatin negatively regulates satellite cell activation and self-renewal. The Journal of Cell Biology. 2003, 162(6):1135-1147
[6]. Goldspink, G., Yang, SY, Skarli, M, Vrbova, G. Local growth regulation is associated with an isoform of IGF-I that is expressed in normal muscles but not in dystrophic muscles. J. Physiol. 1996; 495, 162
[7]. Adams GR, Cheng DC, Haddad F, et al. Skeletal muscle hypertrophy in response to isometric, lengthening, and shortening training bouts of equivalent duration. J Appl Physiol, 2004, 96(5):1613-1618
[8]. Dyson M, Pond J, Joseph J, et al. The stimulation of tissue regeneration by means of ultrasound. Clinical Science, 1968; 35:273-285
[9]. 史仍飞,袁海平.支链氨基酸代谢与运动.上海体育学院学报,2003,27(5):65-67
[10]. 朱晗, 曾凡星.运动对大鼠骨骼肌形态和代谢机能的影响.西安体育学院学报,2005,22(2):61- 64
[11]. Momken I, Lechene P, Koulmann N, et al. Impaired voluntary running capacity of creatine kinase-deficient mice. J Physiol. 2005 , 15; 565(Pt 3): 951-64
[12]. Seger JY, Thorstensson A . Effects of eccentric versus concentric training on thigh muscle strength and EMG. Int J Sports Med. 2005, 26(1):45-52
[13]. Bosco C, Iacovelli M, Tsarpela O, et al. Hormonal responses to whole-body vibration in men. Eur J Appl Physiol 2000;81:449-54
[14]. Di Loreto C, Ranchelli A, Lucidi P, et al. Effects of whole-body vibration exercise on the endocrine system of healthy men. J Endocrinol Invest 2004; 27:323–327
[15]. Cardinale M, Wakeling J. Whole body vibration exercise: are vibrations good for you? Br J Sports Med, 2005: 39:585 - 589
[16]. Huijing PA, Jaspers RT. Adaptation of muscle size and myofascial force transmission: a review and some new experimental results. Scand J Med Sci Sports. 2005 , 15(6):349-80
[17]. Campos GE, Luecke TJ, Wendeln HK, et al. Muscular adaptations in response to three different resistance-training regimens: specificity of repetition maximum training zones. Eur J Appl Physiol. 2002 , 88(1-2):50-60
[18]. Falempin M, In-Albon SF. Influence of brief daily tendon vibration on rat soleus muscle in non-weight-bearing situation. J Appl Physiol. 1999 , 87(1):3-9
[19]. Timson BF. Evaluation of animal models for the study of exercise - induced muscle enlargement [ J ] . Appl Physiol 1990 ; 69 ( 6) : 1935 - 1945
[20]. Goldspink G. Age-related muscle loss and progressive dysfunction in mechanosensitive growth factor signaling. Ann N Y Acad Sci. 2004;1019: 294- 298
[21]. GOLDSPINK G, SCUTT A, LOUGHNA P, et al. Gene expression in skeletal muscle in response to mechanical signals[J]. Am J Physiol, 1992, 262:326-363.
[22]. Adams GR, Haddad F. The relationships among IGF-1, DNA content and protein accumulation during skeletal muscle hypertrophy. J Appl Physiol, 1996,81: 2509-2516.
[23]. Bamman MM, Shipp JR, Jiang J, et al. Mechanical load increases muscle IGF-I and androgen receptor mRNA concentrations in humans. Am J Physiol Endocrinol Metab 2001;280 (3): E383 -90
[24]. Czerwinski SM, Martin JM. Modulation of IGF mRNA abundance during stretch-induced skeletal muscle hypertrophy and regression. J Appl Physiol, 1994, 76: 2026-2030
[25]. Haddad F, Adams G R. Selected contribution: acute cellular and molecular response to resistance exercise. J Appl Physiol, 2002, 93:394-403
[26]. Hill M, Goldspink G. Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite cell activation following local tissue damage[J]. J Physiol, 2003,549:409-418
[27]. Hameed M, Harridge S D, Goldspink G, et al. Sarcopenia and hypertrophy: a role for insulin-like growth factor-1 in aged muscle?[J]. Exerc Sport Sci Rev, 2002,30: 15-19
[28]. 史仍飞,危小焰. 机械生长因子的结构与调节. 医学分子生物学杂志, 2006, 3(4): 316-319
[29]. Gregory R, Adams, Daniel C, et al. Skeletal muscle hypertrophy in response to isometric, lengthening, and shortening training bouts of equivalent duration. J Appl Physiol , 2004, 96: 1613-1618
[30]. Yang S Y, Alnaqeeb M, Simpson H, et al. Cloning and characterization of an IGF-Ⅰ isoform expressed in skeletal muscle subjected to stetch [J]. J muscle Res Cell Motil, 1996, 17:487-495
[31]. Yang S Y, Goldspink G. Different roles of the IGF-ⅠEc peptide (MGF) and mature IGF-Ⅰin myoblast proliferation and differentiation[J]. FEBS Lett, 2002, 522: 156-160
[32]. Mccall G E,Allen D L, Haddad F, et al. Transcriptional regulation of IGF-Ⅰ expression in skeletal muscle[J]. Am J Physiol Cell Physiol, 2003, 285: C831-C839
[33]. Hameed M, Orrell R W, Cobbold M, et al. Expression of IGF-Ⅰ splice variants in young and old human skeletal muscle after high resistance exercise[J]. J Physiol, 2003, 547: 247-254.
[34]. Issurin VB, Liebermann DG, Tenenbaum G. Effect of vibratory stimulation training on maximal force and flexibility. J Sports Sci. 1994;12(6):561-566
[35]. Kerschan-Schindl K, Grampp S, Henk C, et al. Whole-body vibration exercise leads to alterations in muscle blood volume. Clin Physiol. 2001; 21(3):377-382
[36]. Luo J, McNamara B, Moran K. The use of vibration training to enhance muscle strength and power. Sports medicine 2005; 35(1) : 23-41
[1]. HAWKE TJ, GARRY DJ. Myogenic satellite cells: physiology to molecular biology[J]. J Appl Physiol, 2001, 91(2):534~551
[2]. 陈晓萍,范明.肌卫星细胞研究进展[J]. 生理科学进展,2003,34(2):136~138
[3]. VIERCK J, OREILLY B, HOSSNER K, et a1. Satellite cell regulation following myotrauma caused by resistance exercise[J].Cel Biol Int,2000, 24(5):263~272
[4]. ALLEN, R E, TEMM-GROVE, C J, SHEEHAN, SM, et a1. Skeletal muscle satellite cell cultures[J].Methods Cell Biol,1997,52:155~176
[5]. 夏家红,谢艾妮,徐磊,等。大鼠骨骼肌卫星细胞体外培养的实验研究[J].中华实验外科杂志,2005,22(2):214~215
[6]. 司徒镇强,主编. 细胞培养[M], 2004,世界图书出版公司(西安)
[7]. TATSUMI R, SHEEHAN S M, WASAKI H I, et al. Mechanical Stretch Induces Activation of Skeletal Muscle Satellite Cells in Vitro[J]. Experimental Cell Research,2001,267(1):107~114
[8]. 王冰,张冬梅,潘卫庆.CCK-8 法检测疟原虫 HGXPRT 蛋白刺激对淋巴细胞的增殖作用[J].中国热带医学杂志,2006,6(6):949~949
[9]. WU RC, WANG Z, LIU MJ, et al.beta2-integrins mediate a novel form of chemoresistance in cycloheximide-induced U937 apoptosis[J].Cell. Mol. Life Sci,2004,61(16):2071~2082
[10]. ZHENG CH, GAO JQ, ZHANG YP, LIANG WQ. A protein delivery system: biodegradable alginate-chitosan-poly(lactic-co-glycolic acid) composite microspheres[J].Biochem Biophys Res Commun,2004,29,323(4):1321~1327
[11]. SMITH HK, MAXWELL L, RODGERS CD, et al. Exercise-enhanced satellite cell proliferation and new myonuclear accretion in rat skeletal muscle[J].J Appl Physiol,2001,90(4):1407~1414
[12]. VIERCK J, O'REILLY B, HOSSNER K, et al. Satellite cell regulation following myotrauma caused by resistance exercise [J].Cell Biol Int,2000,24(5):263~272
[13]. BRIGHTON CT, STRAFFORD B, GROSS S, et al.The proliferative andsynthetic response of isolated calvarial bone cells of rats to cyclic biaxial mechanical strain [J].J Bone Joint Surg,1991,73(3):320~331
[14]. 李志琴, 章静波.细胞周期及其调控[J ].生理科学进展,2002,33(2):187～189
[15]. KASPAR D, SEIDL W, NEIDLINGER-WILKE C, et a1.Proliferation of human-derived osteoblast-like cells depends on the cycle number and frequency of uniaxial strain [J].J Biomechanics,2002,35(7):873~880
[16]. Allen, R. E., Temm-Grove, C J, Sheehan, S. M., & Rice, G.. Skeletal muscle satellite cell cultures. Methods Cell Biol.,1997, 52: 155–176
[1]. Fleck SJ, Kraemer WJ. Designing resistance training programes. 2nd ed. Champaign (IL):Human Kinetics, 1997
[2]. Nazarov V, Spivak G. Development of athlete’s strength ~ties by means of biomechanical stimulation method Theory Pract Physical Cult (Moscow), 1987;12:37
[3]. Delecluse C, Roelants M, Verschueren S.Strength increase after whole-body vibration compared with resistance training[J].Med Sci Sports Exerc 2003 Jun; 35(6): 1033-41
[4]. Rittweger J,Mutschelknauss M,Felsenberg D.Acute changes in neuromuscular excitability after exhaustive whole body vibration exercise as compared to exhaustion by squatting exercise[J]. Clin Physiol Funct Imaging 2003;23:81-6
[5]. Harris CM.Introduction to the handbook..In: Harris CM,editor.Shock and vibration handbook.New York: McGraw-Hill,1996:1.1-1.27
[6]. Dimarogonas A.Vibration for engineers.2nd ed.London:Prentice Hall International,1996
[7]. Mester J,Spitzenpfeil P,Yue ZY.Vibration loads:potential for strength and power development. In:Komi PV, editor.Strength and power in sport.Oxford:Blackwell,2002:488-501
[8]. Bongiovanni LG.Hagbarth KE,Stjernberg L.Prolonged muscle vibration reducing motor output in maximal voluntary comtractions in man[J]. J Physiol 1990 Apr;423:15-26
[9]. Curry EL,Clelland JA.Effects of the asynnetric tonic neck reflex and high-frequency muscle vibration on isometric wrist externsion strength in normal adults.Phys Ther 1981 Apr;61(4):487-95
[10]. Jackson SW,Turner DL.Prolonged vibration reduces maximal voluntary knee extension performance in both the ipsilateral and the contralateral limb in man[J]. Eur J Appl Physiol ,2003 ;88:380-6
[11]. Humphries B,Warman G, Purton J,et al. The influence of vibration on muscle activation and rate of force development during maximal isometric contractions[J]. J Sports Sci Med 2004;3:16-22
[12]. Issurin VB,Liebermann DG,Tenenbaum G.Effect of vibratory stimulation training on maximal force and flexibility[J]. J Sports Sci 1994, 12:561-6
[13]. Torvinen S,Sievanen H,Jarvinen TA,et al. Effect of 4-min vertical whole body vibration on muscle performance and body balance[J]. Int J Sports Med 2002;23:374-9
[14]. Torvinen S,Kannu P,Sievanen H,et al.Effect of a vibration exposure on muscular performance and body balance: randomized cross-over study[J]. Clin Physiol Funct Imaging 2002 ; 22:145-52
[15]. Issurin VB,Tenenbaum G.Acute and residual effect of vibratory stimulation on explosive strength in elite and amateur athletes[J]. J Sports Sci 1999,17:177-82
[16]. Von Gierke HE,Goldman DE.Effects of shock and vibration on man.In:Harris CM,editor.Shock and vibration handbook. New York:McGraw-Hill,1998:44-1, 44-58
[17]. Akira Okada, Mari Nari, Makoto Ariizumi. Experimental studies on the effects of vibration and noise sympathetic nerve activity in skin[J]. Europe Journal of Applied Physiology, 1991,(62):324-331
[18]. Hiroyuki Nakamura, Takashi Moroji, Hirofumi Nagase. Changes of cerebral vasoactive intestinal polypeptide and somatostatin-like immunoreactivity induced by noise and whole-body vibration in the rat [J]. Europe Journal of Applied physiology, 1994,(68):62-67
[19]. McBride JM, Porcari JP, Scheunke MD. Effect of vibration during fatiguing resistance exercise on subsequent muscle activity during maximal voluntary isometric contractions. J Strength Cond Res. 2004; 18(4):777-81
[20]. Fox EL, Hatthews DK. The physiological basis of physical education and athletics Philadelphia[J]. Sau Nders College Publishers,1981,(49):123-128
[21]. Kerschan-Schindl K, Grampp S, Henk C, et al. Whole-body vibration exercise leads to alterations in muscle blood volume. Clin Physiol 2001, 21:377–82.
[22]. Rittweger J, Ehrig J, Just K, et al. Oxygen uptake in whole-body vibration exercise: influence of vibration frequency, amplitude, and external load[J]. Int J Sports Med 2002;23:428–32.
[23]. Bosco C, Colli R, Introini E, et al. Adaptive responses of human skeletal muscle to vibration exposure[J]. Clin Physiol 1999;19:183–7.
[24]. Bosco C, Iacovelli M, Tsarpela O, et al. Hormonal responses to whole-body vibration in men[J]. Eur J Appl Physiol , 2000, 81: 449–54.
[25]. Torvinen S, Kannus P, Sievanen H, et al. Effect of a vibration exposure on muscular performance and body balance. Randomized cross-over study[J]. Clin Physiol Funct Imaging . 2002, 22:145–52
[26]. Cardinale M, Lim J. Electromyography activity of vastus lateralis muscleduring whole-body vibrations of different frequencies[J]. J Strength Cond Res 2003,17: 621–4.
[27]. De Ruiter CJ, Van Der Linden RM, Van Der Zijden MJ, et al. Short-term effects of whole-body vibration on maximal voluntary isometric knee extensor force and rate of force rise[J]. Eur J Appl Physiol 2003, 88:472–5
[28]. Di Loreto C, Ranchelli A, Lucidi P, et al. Effects of whole-body vibration exercise on the endocrine system of healthy men[J]. J Endocrinol Invest 2004, 27: 323–327
[29]. Bosco C, Cardinale M, Colli R, et al. The influence of whole body vibration on jumping ability[J]. Biol Sport 1998, 15:157–64.
[30]. Cochrane DJ, Legg SJ, Hooker MJ. The short-term effect of whole-body vibration training on vertical jump, sprint, and agility performance[J]. J Strength Cond Res 2004;18:828–32
[31]. Torvinen S, Kannus P, Sievanen H, et al. Effect of four-month vertical whole body vibration on performance and balance[J]. Med Sci Sports Exerc 2002;34:1523–8
[32]. Delecluse C, Roelants M, Verschueren S. Strength increase after whole-body vibration compared with resistance training[J]. Med Sci Sports Exerc 2003;35:1033–41
[33]. Van Nes IJ, Geurts AC, Hendricks HT, et al. Short-term effects of whole-body vibration on postural control in unilateral chronic stroke patients: preliminary evidence[J]. Am J Phys Med Rehabil . 2004;83:867–73
[1]. GOLDSPINK G. Research on mechano growth factor: its potential for optimising physical training as well as misuse in doping[J]. British J Sports Med, 2005, 39:787-788.
[2]. GOLDSPINK G, YANG S Y, SKARLI M, et al. Local growth regulation is associated with an isoform of IGF-Ⅰ that is expressed in normal muscles but not in dystrophic muscles[J]. J Physiol, 1996, 495:162-168.
[3]. NIXON A J, BROWER-TOLAND B D. Primary nucleotide structure of predominant and alternate splice forms of equine like growth factor I and their gene expressions patterns in tissues[J]. Am J Vet Res, 1999, 60: 1234-1241.
[4]. GOLDSPINK G, HARRIDGE S D R. Growth factors and muscle ageing[J]. Experimental Gerontology, 2004, 39: 1433-1438.
[5]. MCKOY G, ASHLEY W, MANDER J, et al. Expression of insulin-like growth factor-I splice variant and structural genes in rabbit skeletal muscle induced by stretch and stimulation[J]. J Physiol, 1999, 516: 583-592.
[6]. GOLDSPINK G. Age-Related Muscle Loss and Progressive Dysfunction in Mechano sensitive Growth Factor Signaling[J]. Ann NY Acad Sci, 2004, 1019: 294-298
[7]. SPANGENBURG E E. IGF-Ⅰ isoforms and ageing skeletal muscle: an “unresponsive” hypertrophy agent? [J]. J Physiol, 2003,547:2-8.
[8]. GOLDSPINK G, SCUTT A, LOUGHNA P, et al. Gene expression in skeletal muscle in response to mechanical signals[J]. Am J Physiol, 1992, 262:326-363.
[9]. BARTON-D, SHOTURMA D I, MUSARO A, et al, Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function[J]. Proc Natl Acad Sci, 1998, 95:15603–15607
[10]. YANG S Y, ALNAQEEB M, SIMPSON H, et al. Cloning and characterization of an IGF-Ⅰ isoform expressed in skeletal muscle subjected to stetch[J]. J muscle Res Cell Motil, 1996, 17:487-495.
[11]. YANG S Y, GOLDSPINK G. Different roles of the IGF-ⅠEc peptide (MGF) and mature IGF-Ⅰ in myoblast proliferation and differentiation[J]. FEBS Lett, 2002, 522: 156-160.
[12]. MCCALL G E,ALLEN D L, HADDAD F, et al. Transcriptional regulation of IGF-Ⅰ expression in skeletal muscle[J]. Am J Physiol Cell Physiol, 2003, 285: C831-C839.
[13]. Zhen Yan,et al. Insulin-like growth factor immunoreactivity increases in muscle after eccentric contractions[J]. J Appl Physiol 1993,74:410
[14]. HADDAD F, ADAMS G R. selected contribution: acute cellular and molecular response to resistance exercise. J Appl Physiol, 2002, 93:394-403.
[15]. HILL M, GOLDSPINK G. Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite cell activation following local tissue damage[J]. J Physiol, 2003,549:409-418.
[16]. HAMEED M, HARRIDGE S D, GOLDSPINK G, et al. Sarcopenia and hypertrophy: a role for insulin-like growth factor-1 in aged muscle?[J]. Exerc Sport Sci Rev, 2002,30: 15-19.
[17]. HAMEED M, LANGE K H, ANDERSEN J L, et al. The effect of recombinant human growth hormone and resistance training on IGF-Ⅰ mRNA expression in the muscles of elderly men[J]. J Physiol, 2004, 555, 231-240.
[18]. CORTES E, FONG LF, HAMEED M, et al. Insulin-like growth factor-1 gene splice variants as markers of muscle damage in levator ani muscle after the first vaginal delivery[J]. Am J Obstet Gynecol, 2005,193(1):64-70.
[19]. OWINO V, YANG S Y, GOLDSPINK G. Age-related loss of skeletal muscle function and the inability to express the autocrine form of insulin-like growth factor-1 (MGF) in response to mechanical overload[J]. FEBS Lett, 2001, 505: 259-263.
[20]. HAMEED M, ORRELL R W, COBBOLD M, et al. Expression of IGF-Ⅰ splice variants in young and old human skeletal muscle after high resistance exercise[J]. J Physiol, 2003, 547: 247-254.
[21]. RENNIE M J. Claims for the anabolic effects of growth hormone: a case of the Emperor’s new clothes?[J]. Br J Sports Med, 2003, 37: 100.
[22]. KEIJI I, EMINA I, KIM D S, et al. Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice[J]. J Physiol, 2004, 560: 341-349.
[23]. LEE J S. Regulation of muscle mass by myostatin. Annu Rev Cell Dev Biol, 2004, 20:61-86.
[24]. GOLDSPINK G. Age-related loss of skeletal muscle function: impairment of gene expression[J]. J Musculoskelet Neuronal Interact, 2004,4(2):143-147.
[25]. KIM J S, CROSS J M, BAMMAN M M, et al. Impact of resistance loading on myostain expression and cell cycle regulation in young and older men and women[J]. Am J physiol Endocrinol Metab, 2005, 288(6): E1110-1119.
[1]. Mauro A. The satellite cell of skeletal muscle implantation[J]. J Biophys Biochem Cytol, 1961,9:493~496
[2]. Ferrari G, Cusella D,Angelis G,et al. Muscle regeneration by bone marrow—derived myogenic progenitors[J]. J Cell Biol, 1999, 147(4): 869~878
[3]. Sehultz E , McCormick KM.Skeletal muscle satellite cells[J]. Rev Physiol Biochem Pharmacol, 1994, 123: 213~257
[4]. Ordabl CP, wiuis RA, and Denetclaw W. Determination and morphogenesis inmyogenic progenitor cells: an experimental embryological approach. Curt Top Dev Biol, 2000, 48: 319~367
[5]. Ordabl CP.Myogenic shape —shifters. J Cel Biol,1999,147:695~698
[6]. De Angelis L,Berghella L,Coletta M,et a1.Skeletal myogenic progenitors originating from embryonic dorsal aorta coexpress endothelial and myogenic markers an d contribute to postnatal muscle growth and regeneration.J Cell Biol,1999,147 :869~878
[7]. Shi X, Garry DJ. Muscle stem cells in development, regeneration, and disease. Genes Dev, 2006 ;20(13):1692-708
[8]. Schultz E. Satellite Cell Proliferative Compartments in Growing Skeletal Muscles Developmental Biology, 1996,175(1):84-94
[9]. Bischoff R. The satellite cell and muscle regeneration. Myology, 1994, 97~118
[10]. Pavlath G. Isolation, purification and growth of skeletal muscle cells. Methods of Molecular Medicine: Human Cell Culture Protocols. 1996,307~318
[11]. Chen J, Goldhamer D. Skeletal muscle stem cells. Reprod Biol Endocrin 2003, 1: 101~107
[12]. Carlson B, Factors influencing the repair and adaptation of muscle in aged individuals: satellite cells and innervation. J Gerontol, 1995, 50A:96~100
[13]. Roth S, Martel G, Ivey F, et al. Skeletal muscle satellite cell populations in healthy young and older men and women. Anat Rec 2000; 260:351-358
[14]. Chultz E, Jaryszak D. Effects of skeletal muscle regeneration on the proliferation potential of satellite cells. Mech Aging Dev, 1985,30:63-72
[15]. Gibson M, Schultz E. Age-related difference in the absolute number of satellite cells in rat soleus and extensor digitorum longus muscle. Musc Nerve. 1983, 6:574~580
[16]. Gibson MC and Schultz E.Distribution of satelite cells and their relationship to specific fiber types in soleus and extensor digitorum longus muscle.Anat Rec,1982,202: 329—337
[17]. Asakura A, Seale P, Girgis-Gabardo A, et al. Myogenic specification of sidepopulation cells in skeletal muscle. J Cell Biol, 2002,159:123~134
[18]. Goldring K, Partridge T, Watt D. Muscle stem cells. J Pathol 2002;197:457~467
[19]. Vierck J, Reilly B, Hossner K, et a1. Satellite cell resulation following myotrauma caused by resistance exercise[J]. Cel Biol Int, 2000, 24: 263—272
[20]. 沈燕国,徐建光,顾玉东. 成肌调节因子 MyoD 和 Myf-5 在人体失神经骨骼肌中的表达及其临床意义[J]. 复旦大学学报, 2002, 29 (4): 264～267
[21]. Braun T, Rudinick MA , Arnold HH , et al . Targeted inactivation of the mouse regulatory gene Myf25 results in distal rib development and early postnatal death in homoxygous mouse mutant[J] . Cell ,1992 ,71 :369
[22]. Rudinick BT,Hinuma S, Jaenish R. MyoD or Myf25 is required for the formation of skeletal muscle[J] . Cell ,1993 ,75 :1351
[23]. Cooper RN ,Taybukhsh S ,Mouly G, et al . In vivo satellite cell activation via Myf-5 and MyoD in regenerating mouse skeletal muscle[J] . J Cell Sci ,1999 ,112 :2895.
[24]. Caroni P. Activity-sensitive signaling by muscle-deriver insulin like growth factors in the developing and regenerating neuromuscular system[J] . Annu N Y Acad Sci , 1993 , 692 : 209～222.
[25]. DeVol DL,Rotwein P,Sadow JL,et a1.Activation of insulin-like growth factor gene expression during work- induced skeletal muscle growth [J]. Am J Physiol, 1990, 259(1 Pt 1): E89-95
[26]. Yang H, Alnaqeeb M, Simpson H, et al. Changes in muscle fibre type, muscle mass and IGF- I gene expression in rabbit skeletal muscle subjected to stretch[J]. J Anat, 1997, 190 (Pt4):613- 622.
[27]. Yang S, Alnaqeeb M, Simpson H, et al. Cloning and characterization of an IGF- I isoform expressed in skeletal muscle subjected to stretch [J]. J Muscle Res Cell Motil, 1996,17(4):487-495.
[28]. Musaro A, MeCullagh K, Paul A, et al. Localized IGF-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle[J]. NatGenet, 200l, 27(2):195- 200.
[29]. Coleman ME, DeMayo F, Yin KC, et al. Myogenic vector expression of insulin- like growth factor I stimulates muscle cell differentiation and myofiberhypertrophy intransgenic mice[J]. J Biol Chem, 1995, 270(20):12109~12116
[30]. Barton-Davis ER, Shoturma DI, Musaro A, et al. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function Proc Natl Acad Sci USA. 1998, 95:15603~15607
[31]. Stewart CE, Rotwein P. Insulin-like Growth Factor-II is an autocrine survival factor for differentiating myoblasts[J]. J Biol Chem, 1996, 271:11330~11338
[32]. Florini JR, Magri KA, Ewton DZ, et al. “Spontaneous” differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II[J]. Cancer Res, 1991,51:5997~6000
[33]. Sheehan SM, Ronald E. Allen, Skeletal muscle satellite cell proliferation in response to members of the fibroblast growth factor family and hepatocyte growth factor. J Cell Physiol, 1999,181(3):499~506
[34]. Sheehan SM, Tatsumi R, Temm-Grove CJ, et al. HGF is an autocrine growth factor for skeletal muscle satellite cells in vitro[J]. Muscle Nerve. 2000;23(2):239~245
[35]. Miller K, Thaloor D, Matteson S, et al. Hepatocyte growth factor affects satellite cell activation and differentiation in regenerating skeletal muscle[J]. Am J Physiol Cell Physiol 2002,278:C174~C181
[36]. McPherron AC, Lawler AM, Lee SJ. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member[J]. Nature, 1997, 387(6628):83-90
[37]. 杨威, 王琨, 陈岩, 等. 重组肌肉抑制素功能分析及其对鸡肌肉发育的抑制作用[J ]. 生物化学与生物物理学报, 2003, 35 (11) : 1016-1022
[38]. Thomas M, Langley B, Berry C, et al. Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation[J]. J Biol Chem, 2000, 275: 40235-40243
[39]. Michael P, Spiller, Ravi Kambadur, et al. The myostatin gene is a downstream target gene of basic helix-loop-helix transcription factor MyoD [J]. Molecular and Cellular Biology, 2002, 22 (20) : 7066~7082.
[40]. Langley B, Thomas M, Bishop A, et al. Myostatin inhibits myoblast differentiation by down –regulating MyoD expression [J]. The Journal of Biological Chemistry, 2002, 277 (51) : 9831-49840
[41]. Rosenblatt JD, Yang D and Parry DJ. Satellite cell activity is required forhypertrophy of overload adult rat muscle [J]. Muscle Nerve, 1994,17: 608~613
[42]. Tatsumi R, Sheehan SM, Wasaki HI, et al. Mechanical Stretch Induces Activation of Skeletal Muscle Satellite Cells in Vitro[J]. Experimental Cell Research , 2001, 267: 107–114
[43]. Grounds MD. Muscle regeneration: molecular aspects and therapeutic implications. Curt Opin Neurol, 1999, 12: 535-543
[44]. Vierck J, Oreilly B, Hossner K, et a1. Satellite cell regulation following myotrauma caused by resistance exercise[J]. Cel Biol Int, 2000, 24(5): 263~272
[45]. 周锦琳.急性运动对大鼠骨骼肌卫星细胞增值能力和不同 pH 值对骨骼肌细胞胞浆 Ca2+代谢的影响。北京体育大学博士学位(毕业)论文,2003 年 4 月
[46]. 史仍飞,危小焰,卞玉华.机械牵拉刺激对大鼠骨骼肌卫星细胞增殖的影响.体育科学,2007,收录
[2]. Issurin VB, Tenenbaum G. Acute and residual effects of vibratory stimulation on explosive strength in elite and amateur athletes. J Sports Science, 1999;17: 177-182
[3]. Cardinale M, Lim J. The acute effects of two different whole body vibration frequencies on vertical jump performance. Med. Sport, 2003, 56: 287-292
[4]. Wei Xiaoyan , Peng Chunzheng . A New Method of Muscle Strength Training By Vibrating Platform. the Proceedings of 2004 Pre-Olympic Congress, Vol.1 pp473, 2004, Thessaloniki, Greece.
[5]. 危小焰,彭春政.振动力量训练对肌肉力量的影响研究.体育科研,2004, 25(4): 53-57
[6]. 彭春政,危小焰. 抗负荷力量训练附加全身振动刺激对肌力训练效果的影响.上海体育学院学报,2003,27(1):70-73
[7]. Jin Luo, Brian McNamara and Kieran Moran. The use of vibration training to enhance muscle strength and power. Sports Med. 2005, 35(1):23-41
[8]. Chakravarthy MV, Davis BS, Booth FW. IGF-I restores satellite cell proliferative potential in immobilized old skeletal muscle. J Appl Physiol, 2000, 89(4):1365-1379
[9]. Vary TC, Kimball SR Effect of sepsis on eIE4E availability in skeletal muscle. Am J Physiol Endocrinol Metab, 2000, 279(5): E1178-84
[10]. Coleman ME, DeMayo F, Yin KC, et al. Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice. J Biol Chem, 1995, 270(20):12109-16.
[11]. Carson JA, Yan Z, Booth FW, et al. Regulation of skeletal alpha-actin promoter in young chickens during hypertrophy caused by stretch overload. Am J Physiol. 1995, 268(4):C918-24
[12]. Mayhew TP, Rothstein JM, Finucane SD, et al. Muscular adaptation to concentric and eccentric exercise at equal power levels. Med Sci Sports Exerc 1995, 27(6): 868–873
[13]. Goldspink G. Mechanical signals, IGF-I gene splicing, and muscle adaptation. Physiology, 2005, 20:232~238
[14]. Goldspink G. Research on mechano growth factor: its potential for optimising physical training as well as misuse in doping[J]. British J Sports Med, 2005, 39:787-788
[15]. Goldspink G, Yang S Y, Skarli M, et al. Local growth regulation is associated with an isoform of IGF-Ⅰ that is expressed in normal muscles but not in dystrophic muscles[J]. J Physiol, 1996, 495:162-168
[16]. Yang S Y, Alnaqeeb M, Simpson H, et al. Cloning and characterization of an IGF-Ⅰ isoform expressed in skeletal muscle subjected to stetch[J]. J muscle Res Cell Motil, 1996, 17:487-495
[17]. Yang S Y, Goldspink G. Different roles of the IGF-ⅠEc peptide (MGF) and mature IGF-Ⅰ in myoblast proliferation and differentiation[J]. FEBS Lett, 2002, 522: 156-160
[18]. Hameed M, Lange K H, Andersen J L, et al. The effect of recombinant human growth hormone and resistance training on IGF-Ⅰ mRNA expression in themuscles of elderly men[J]. J Physiol, 2004, 555, 231-240
[19]. Issurin VB. Vibrations and their applications in sport. J Sports Med Phys Fitness. 2005;45(3):324-336
[20]. Issurin VB, Liebermann DG, Tenenbaum G. Effect of vibratory stimulation training on maximal force and flexibility. J Sports Sci. 1994;12(6):561-566
[21]. McBride JM, Porcari JP, Scheunke MD. Effect of vibration during fatiguing resistance exercise on subsequent muscle activity during maximal voluntary isometric contractions. J Strength Cond Res. 2004, 18(4):777-781
[22]. Cardinale M, Wakeling J. Whole body vibration exercise: are vibrations good for you?. Br J Sports Med. 2005, 39(9):585-589
[23]. Rittweger J, Ehrig J, Just K, et al. Oxygen uptake in whole-body vibration exercise: influence of vibration frequency, amplitude, and external load. Int J Sports Med 2002;23:428–432
[24]. Oxlund B S, Qrtoft G, Andreassen T T, et al. Low-intensity, high-frequency vibration appears to prevent the decrease in strength of the femur and tibia associated with ovariectomy of adult rats. Bone. 2003, 32(1):69 ~77
[25]. Luo J, McNamara B, Moran K. The use of vibration training to enhance muscle strength and power. Sports medicine 2005; 35(1) : 23~41
[26]. Kirsten Legerlotz, Peter Schjerling, Henning Langberg, et al. The effect of running, strength and vibration strength training on the mechanical, morphological and biochemical properties of the Achilles tendon in rats. J Appl Physiol, 2007, 102(2):564~572
[27]. 张爱芳,主编.实用运动生物化学[M], 北京: 北京体育大学出版社, 2005
[28]. Bosco C, Colli R, Introini E, et al. Adaptive responses of human skeletal muscle to vibration exposure. Clin Physiol 1999;19:183~187
[29]. Bosco C, Iacovelli M, Tsarpela O, et al. Hormonal responses to whole-body vibration in men. Eur J Appl Physiol 2000;81: 449 ~ 454.
[30]. Delecluse,Roelants M, Verschueren N. Strength Increase after Whole-Body Vibration Compared with Resistance Training. Med. Sci. Sports Exerc., 2003, 35(6):1033~ 1041
[31]. De Luca A, Pierno S, Liantonio A, et al. Enhnced dystrophic progression in mdx mice by exercise and beneficial effects of taurine and insulin-like growthfactor-1. J Pharmacol Exp Ther. 2003,304:453~463
[32]. Mulder ER, Stegeman DF, Gerrits KH, et al. Strength, size and activation of knee extensors followed during 8 weeks of horizontal bed rest and the influence of a countermeasure. Eur J Appl Physiol. 2006;97(6):706-15
[33]. Von Gierke HE,Goldman DE. Effects of shock and vibration on man.In:Harris CM,editor.Shock and vibration handbook.New York:McGraw-Hill,1998:44-1-44-58
[34]. Terada Shin, Toshiko Yokozeki, Kentaro Kawanaka, et al. Effects of high-intensity swimming training on GLUT-4 and glucose transport activity in rat skeletal muscle. J Appl Physiol, 2001,90: 2019–202
[1]. Akira Okada, Mari Nari, Makoto Ariizumi. Experimental studies on the effects of vibration and noise sympathetic nerve activity in skin[J]. Europe Journal of Applied Physiology, 1991,(62):324-331
[2]. Von Gierke HE,Goldman DE.Effects of shock and vibration on man.In:Harris CM,editor.Shock and vibration handbook.New York:McGraw-Hill,1998:44-1-44-58
[3]. C.-C.Mao, K.C.McGill and L.J. Dorfan. Muscle vibration facilitates orferly recruitment of motor units[J].Electromyogr.Clinical. Neurophysiology, 1990, (30):245-252
[4]. Fox, E.L. and Hatthews. D.K. The Physiological Basis of Physical Education and Athletics Philadelphia[J].PA:Sau Nders College Publishers,1981, (49):123-128
[5]. Seumas McCroskery, et al . Myostatin negatively regulates satellite cell activation and self-renewal. The Journal of Cell Biology. 2003, 162(6):1135-1147
[6]. Goldspink, G., Yang, SY, Skarli, M, Vrbova, G. Local growth regulation is associated with an isoform of IGF-I that is expressed in normal muscles but not in dystrophic muscles. J. Physiol. 1996; 495, 162
[7]. Adams GR, Cheng DC, Haddad F, et al. Skeletal muscle hypertrophy in response to isometric, lengthening, and shortening training bouts of equivalent duration. J Appl Physiol, 2004, 96(5):1613-1618
[8]. Dyson M, Pond J, Joseph J, et al. The stimulation of tissue regeneration by means of ultrasound. Clinical Science, 1968; 35:273-285
[9]. 史仍飞,袁海平.支链氨基酸代谢与运动.上海体育学院学报,2003,27(5):65-67
[10]. 朱晗, 曾凡星.运动对大鼠骨骼肌形态和代谢机能的影响.西安体育学院学报,2005,22(2):61- 64
[11]. Momken I, Lechene P, Koulmann N, et al. Impaired voluntary running capacity of creatine kinase-deficient mice. J Physiol. 2005 , 15; 565(Pt 3): 951-64
[12]. Seger JY, Thorstensson A . Effects of eccentric versus concentric training on thigh muscle strength and EMG. Int J Sports Med. 2005, 26(1):45-52
[13]. Bosco C, Iacovelli M, Tsarpela O, et al. Hormonal responses to whole-body vibration in men. Eur J Appl Physiol 2000;81:449-54
[14]. Di Loreto C, Ranchelli A, Lucidi P, et al. Effects of whole-body vibration exercise on the endocrine system of healthy men. J Endocrinol Invest 2004; 27:323–327
[15]. Cardinale M, Wakeling J. Whole body vibration exercise: are vibrations good for you? Br J Sports Med, 2005: 39:585 - 589
[16]. Huijing PA, Jaspers RT. Adaptation of muscle size and myofascial force transmission: a review and some new experimental results. Scand J Med Sci Sports. 2005 , 15(6):349-80
[17]. Campos GE, Luecke TJ, Wendeln HK, et al. Muscular adaptations in response to three different resistance-training regimens: specificity of repetition maximum training zones. Eur J Appl Physiol. 2002 , 88(1-2):50-60
[18]. Falempin M, In-Albon SF. Influence of brief daily tendon vibration on rat soleus muscle in non-weight-bearing situation. J Appl Physiol. 1999 , 87(1):3-9
[19]. Timson BF. Evaluation of animal models for the study of exercise - induced muscle enlargement [ J ] . Appl Physiol 1990 ; 69 ( 6) : 1935 - 1945
[20]. Goldspink G. Age-related muscle loss and progressive dysfunction in mechanosensitive growth factor signaling. Ann N Y Acad Sci. 2004;1019: 294- 298
[21]. GOLDSPINK G, SCUTT A, LOUGHNA P, et al. Gene expression in skeletal muscle in response to mechanical signals[J]. Am J Physiol, 1992, 262:326-363.
[22]. Adams GR, Haddad F. The relationships among IGF-1, DNA content and protein accumulation during skeletal muscle hypertrophy. J Appl Physiol, 1996,81: 2509-2516.
[23]. Bamman MM, Shipp JR, Jiang J, et al. Mechanical load increases muscle IGF-I and androgen receptor mRNA concentrations in humans. Am J Physiol Endocrinol Metab 2001;280 (3): E383 -90
[24]. Czerwinski SM, Martin JM. Modulation of IGF mRNA abundance during stretch-induced skeletal muscle hypertrophy and regression. J Appl Physiol, 1994, 76: 2026-2030
[25]. Haddad F, Adams G R. Selected contribution: acute cellular and molecular response to resistance exercise. J Appl Physiol, 2002, 93:394-403
[26]. Hill M, Goldspink G. Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite cell activation following local tissue damage[J]. J Physiol, 2003,549:409-418
[27]. Hameed M, Harridge S D, Goldspink G, et al. Sarcopenia and hypertrophy: a role for insulin-like growth factor-1 in aged muscle?[J]. Exerc Sport Sci Rev, 2002,30: 15-19
[28]. 史仍飞,危小焰. 机械生长因子的结构与调节. 医学分子生物学杂志, 2006, 3(4): 316-319
[29]. Gregory R, Adams, Daniel C, et al. Skeletal muscle hypertrophy in response to isometric, lengthening, and shortening training bouts of equivalent duration. J Appl Physiol , 2004, 96: 1613-1618
[30]. Yang S Y, Alnaqeeb M, Simpson H, et al. Cloning and characterization of an IGF-Ⅰ isoform expressed in skeletal muscle subjected to stetch [J]. J muscle Res Cell Motil, 1996, 17:487-495
[31]. Yang S Y, Goldspink G. Different roles of the IGF-ⅠEc peptide (MGF) and mature IGF-Ⅰin myoblast proliferation and differentiation[J]. FEBS Lett, 2002, 522: 156-160
[32]. Mccall G E,Allen D L, Haddad F, et al. Transcriptional regulation of IGF-Ⅰ expression in skeletal muscle[J]. Am J Physiol Cell Physiol, 2003, 285: C831-C839
[33]. Hameed M, Orrell R W, Cobbold M, et al. Expression of IGF-Ⅰ splice variants in young and old human skeletal muscle after high resistance exercise[J]. J Physiol, 2003, 547: 247-254.
[34]. Issurin VB, Liebermann DG, Tenenbaum G. Effect of vibratory stimulation training on maximal force and flexibility. J Sports Sci. 1994;12(6):561-566
[35]. Kerschan-Schindl K, Grampp S, Henk C, et al. Whole-body vibration exercise leads to alterations in muscle blood volume. Clin Physiol. 2001; 21(3):377-382
[36]. Luo J, McNamara B, Moran K. The use of vibration training to enhance muscle strength and power. Sports medicine 2005; 35(1) : 23-41
[1]. HAWKE TJ, GARRY DJ. Myogenic satellite cells: physiology to molecular biology[J]. J Appl Physiol, 2001, 91(2):534~551
[2]. 陈晓萍,范明.肌卫星细胞研究进展[J]. 生理科学进展,2003,34(2):136~138
[3]. VIERCK J, OREILLY B, HOSSNER K, et a1. Satellite cell regulation following myotrauma caused by resistance exercise[J].Cel Biol Int,2000, 24(5):263~272
[4]. ALLEN, R E, TEMM-GROVE, C J, SHEEHAN, SM, et a1. Skeletal muscle satellite cell cultures[J].Methods Cell Biol,1997,52:155~176
[5]. 夏家红,谢艾妮,徐磊,等。大鼠骨骼肌卫星细胞体外培养的实验研究[J].中华实验外科杂志,2005,22(2):214~215
[6]. 司徒镇强,主编. 细胞培养[M], 2004,世界图书出版公司(西安)
[7]. TATSUMI R, SHEEHAN S M, WASAKI H I, et al. Mechanical Stretch Induces Activation of Skeletal Muscle Satellite Cells in Vitro[J]. Experimental Cell Research,2001,267(1):107~114
[8]. 王冰,张冬梅,潘卫庆.CCK-8 法检测疟原虫 HGXPRT 蛋白刺激对淋巴细胞的增殖作用[J].中国热带医学杂志,2006,6(6):949~949
[9]. WU RC, WANG Z, LIU MJ, et al.beta2-integrins mediate a novel form of chemoresistance in cycloheximide-induced U937 apoptosis[J].Cell. Mol. Life Sci,2004,61(16):2071~2082
[10]. ZHENG CH, GAO JQ, ZHANG YP, LIANG WQ. A protein delivery system: biodegradable alginate-chitosan-poly(lactic-co-glycolic acid) composite microspheres[J].Biochem Biophys Res Commun,2004,29,323(4):1321~1327
[11]. SMITH HK, MAXWELL L, RODGERS CD, et al. Exercise-enhanced satellite cell proliferation and new myonuclear accretion in rat skeletal muscle[J].J Appl Physiol,2001,90(4):1407~1414
[12]. VIERCK J, O'REILLY B, HOSSNER K, et al. Satellite cell regulation following myotrauma caused by resistance exercise [J].Cell Biol Int,2000,24(5):263~272
[13]. BRIGHTON CT, STRAFFORD B, GROSS S, et al.The proliferative andsynthetic response of isolated calvarial bone cells of rats to cyclic biaxial mechanical strain [J].J Bone Joint Surg,1991,73(3):320~331
[14]. 李志琴, 章静波.细胞周期及其调控[J ].生理科学进展,2002,33(2):187～189
[15]. KASPAR D, SEIDL W, NEIDLINGER-WILKE C, et a1.Proliferation of human-derived osteoblast-like cells depends on the cycle number and frequency of uniaxial strain [J].J Biomechanics,2002,35(7):873~880
[16]. Allen, R. E., Temm-Grove, C J, Sheehan, S. M., & Rice, G.. Skeletal muscle satellite cell cultures. Methods Cell Biol.,1997, 52: 155–176
[1]. Fleck SJ, Kraemer WJ. Designing resistance training programes. 2nd ed. Champaign (IL):Human Kinetics, 1997
[2]. Nazarov V, Spivak G. Development of athlete’s strength ~ties by means of biomechanical stimulation method Theory Pract Physical Cult (Moscow), 1987;12:37
[3]. Delecluse C, Roelants M, Verschueren S.Strength increase after whole-body vibration compared with resistance training[J].Med Sci Sports Exerc 2003 Jun; 35(6): 1033-41
[4]. Rittweger J,Mutschelknauss M,Felsenberg D.Acute changes in neuromuscular excitability after exhaustive whole body vibration exercise as compared to exhaustion by squatting exercise[J]. Clin Physiol Funct Imaging 2003;23:81-6
[5]. Harris CM.Introduction to the handbook..In: Harris CM,editor.Shock and vibration handbook.New York: McGraw-Hill,1996:1.1-1.27
[6]. Dimarogonas A.Vibration for engineers.2nd ed.London:Prentice Hall International,1996
[7]. Mester J,Spitzenpfeil P,Yue ZY.Vibration loads:potential for strength and power development. In:Komi PV, editor.Strength and power in sport.Oxford:Blackwell,2002:488-501
[8]. Bongiovanni LG.Hagbarth KE,Stjernberg L.Prolonged muscle vibration reducing motor output in maximal voluntary comtractions in man[J]. J Physiol 1990 Apr;423:15-26
[9]. Curry EL,Clelland JA.Effects of the asynnetric tonic neck reflex and high-frequency muscle vibration on isometric wrist externsion strength in normal adults.Phys Ther 1981 Apr;61(4):487-95
[10]. Jackson SW,Turner DL.Prolonged vibration reduces maximal voluntary knee extension performance in both the ipsilateral and the contralateral limb in man[J]. Eur J Appl Physiol ,2003 ;88:380-6
[11]. Humphries B,Warman G, Purton J,et al. The influence of vibration on muscle activation and rate of force development during maximal isometric contractions[J]. J Sports Sci Med 2004;3:16-22
[12]. Issurin VB,Liebermann DG,Tenenbaum G.Effect of vibratory stimulation training on maximal force and flexibility[J]. J Sports Sci 1994, 12:561-6
[13]. Torvinen S,Sievanen H,Jarvinen TA,et al. Effect of 4-min vertical whole body vibration on muscle performance and body balance[J]. Int J Sports Med 2002;23:374-9
[14]. Torvinen S,Kannu P,Sievanen H,et al.Effect of a vibration exposure on muscular performance and body balance: randomized cross-over study[J]. Clin Physiol Funct Imaging 2002 ; 22:145-52
[15]. Issurin VB,Tenenbaum G.Acute and residual effect of vibratory stimulation on explosive strength in elite and amateur athletes[J]. J Sports Sci 1999,17:177-82
[16]. Von Gierke HE,Goldman DE.Effects of shock and vibration on man.In:Harris CM,editor.Shock and vibration handbook. New York:McGraw-Hill,1998:44-1, 44-58
[17]. Akira Okada, Mari Nari, Makoto Ariizumi. Experimental studies on the effects of vibration and noise sympathetic nerve activity in skin[J]. Europe Journal of Applied Physiology, 1991,(62):324-331
[18]. Hiroyuki Nakamura, Takashi Moroji, Hirofumi Nagase. Changes of cerebral vasoactive intestinal polypeptide and somatostatin-like immunoreactivity induced by noise and whole-body vibration in the rat [J]. Europe Journal of Applied physiology, 1994,(68):62-67
[19]. McBride JM, Porcari JP, Scheunke MD. Effect of vibration during fatiguing resistance exercise on subsequent muscle activity during maximal voluntary isometric contractions. J Strength Cond Res. 2004; 18(4):777-81
[20]. Fox EL, Hatthews DK. The physiological basis of physical education and athletics Philadelphia[J]. Sau Nders College Publishers,1981,(49):123-128
[21]. Kerschan-Schindl K, Grampp S, Henk C, et al. Whole-body vibration exercise leads to alterations in muscle blood volume. Clin Physiol 2001, 21:377–82.
[22]. Rittweger J, Ehrig J, Just K, et al. Oxygen uptake in whole-body vibration exercise: influence of vibration frequency, amplitude, and external load[J]. Int J Sports Med 2002;23:428–32.
[23]. Bosco C, Colli R, Introini E, et al. Adaptive responses of human skeletal muscle to vibration exposure[J]. Clin Physiol 1999;19:183–7.
[24]. Bosco C, Iacovelli M, Tsarpela O, et al. Hormonal responses to whole-body vibration in men[J]. Eur J Appl Physiol , 2000, 81: 449–54.
[25]. Torvinen S, Kannus P, Sievanen H, et al. Effect of a vibration exposure on muscular performance and body balance. Randomized cross-over study[J]. Clin Physiol Funct Imaging . 2002, 22:145–52
[26]. Cardinale M, Lim J. Electromyography activity of vastus lateralis muscleduring whole-body vibrations of different frequencies[J]. J Strength Cond Res 2003,17: 621–4.
[27]. De Ruiter CJ, Van Der Linden RM, Van Der Zijden MJ, et al. Short-term effects of whole-body vibration on maximal voluntary isometric knee extensor force and rate of force rise[J]. Eur J Appl Physiol 2003, 88:472–5
[28]. Di Loreto C, Ranchelli A, Lucidi P, et al. Effects of whole-body vibration exercise on the endocrine system of healthy men[J]. J Endocrinol Invest 2004, 27: 323–327
[29]. Bosco C, Cardinale M, Colli R, et al. The influence of whole body vibration on jumping ability[J]. Biol Sport 1998, 15:157–64.
[30]. Cochrane DJ, Legg SJ, Hooker MJ. The short-term effect of whole-body vibration training on vertical jump, sprint, and agility performance[J]. J Strength Cond Res 2004;18:828–32
[31]. Torvinen S, Kannus P, Sievanen H, et al. Effect of four-month vertical whole body vibration on performance and balance[J]. Med Sci Sports Exerc 2002;34:1523–8
[32]. Delecluse C, Roelants M, Verschueren S. Strength increase after whole-body vibration compared with resistance training[J]. Med Sci Sports Exerc 2003;35:1033–41
[33]. Van Nes IJ, Geurts AC, Hendricks HT, et al. Short-term effects of whole-body vibration on postural control in unilateral chronic stroke patients: preliminary evidence[J]. Am J Phys Med Rehabil . 2004;83:867–73
[1]. GOLDSPINK G. Research on mechano growth factor: its potential for optimising physical training as well as misuse in doping[J]. British J Sports Med, 2005, 39:787-788.
[2]. GOLDSPINK G, YANG S Y, SKARLI M, et al. Local growth regulation is associated with an isoform of IGF-Ⅰ that is expressed in normal muscles but not in dystrophic muscles[J]. J Physiol, 1996, 495:162-168.
[3]. NIXON A J, BROWER-TOLAND B D. Primary nucleotide structure of predominant and alternate splice forms of equine like growth factor I and their gene expressions patterns in tissues[J]. Am J Vet Res, 1999, 60: 1234-1241.
[4]. GOLDSPINK G, HARRIDGE S D R. Growth factors and muscle ageing[J]. Experimental Gerontology, 2004, 39: 1433-1438.
[5]. MCKOY G, ASHLEY W, MANDER J, et al. Expression of insulin-like growth factor-I splice variant and structural genes in rabbit skeletal muscle induced by stretch and stimulation[J]. J Physiol, 1999, 516: 583-592.
[6]. GOLDSPINK G. Age-Related Muscle Loss and Progressive Dysfunction in Mechano sensitive Growth Factor Signaling[J]. Ann NY Acad Sci, 2004, 1019: 294-298
[7]. SPANGENBURG E E. IGF-Ⅰ isoforms and ageing skeletal muscle: an “unresponsive” hypertrophy agent? [J]. J Physiol, 2003,547:2-8.
[8]. GOLDSPINK G, SCUTT A, LOUGHNA P, et al. Gene expression in skeletal muscle in response to mechanical signals[J]. Am J Physiol, 1992, 262:326-363.
[9]. BARTON-D, SHOTURMA D I, MUSARO A, et al, Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function[J]. Proc Natl Acad Sci, 1998, 95:15603–15607
[10]. YANG S Y, ALNAQEEB M, SIMPSON H, et al. Cloning and characterization of an IGF-Ⅰ isoform expressed in skeletal muscle subjected to stetch[J]. J muscle Res Cell Motil, 1996, 17:487-495.
[11]. YANG S Y, GOLDSPINK G. Different roles of the IGF-ⅠEc peptide (MGF) and mature IGF-Ⅰ in myoblast proliferation and differentiation[J]. FEBS Lett, 2002, 522: 156-160.
[12]. MCCALL G E,ALLEN D L, HADDAD F, et al. Transcriptional regulation of IGF-Ⅰ expression in skeletal muscle[J]. Am J Physiol Cell Physiol, 2003, 285: C831-C839.
[13]. Zhen Yan,et al. Insulin-like growth factor immunoreactivity increases in muscle after eccentric contractions[J]. J Appl Physiol 1993,74:410
[14]. HADDAD F, ADAMS G R. selected contribution: acute cellular and molecular response to resistance exercise. J Appl Physiol, 2002, 93:394-403.
[15]. HILL M, GOLDSPINK G. Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite cell activation following local tissue damage[J]. J Physiol, 2003,549:409-418.
[16]. HAMEED M, HARRIDGE S D, GOLDSPINK G, et al. Sarcopenia and hypertrophy: a role for insulin-like growth factor-1 in aged muscle?[J]. Exerc Sport Sci Rev, 2002,30: 15-19.
[17]. HAMEED M, LANGE K H, ANDERSEN J L, et al. The effect of recombinant human growth hormone and resistance training on IGF-Ⅰ mRNA expression in the muscles of elderly men[J]. J Physiol, 2004, 555, 231-240.
[18]. CORTES E, FONG LF, HAMEED M, et al. Insulin-like growth factor-1 gene splice variants as markers of muscle damage in levator ani muscle after the first vaginal delivery[J]. Am J Obstet Gynecol, 2005,193(1):64-70.
[19]. OWINO V, YANG S Y, GOLDSPINK G. Age-related loss of skeletal muscle function and the inability to express the autocrine form of insulin-like growth factor-1 (MGF) in response to mechanical overload[J]. FEBS Lett, 2001, 505: 259-263.
[20]. HAMEED M, ORRELL R W, COBBOLD M, et al. Expression of IGF-Ⅰ splice variants in young and old human skeletal muscle after high resistance exercise[J]. J Physiol, 2003, 547: 247-254.
[21]. RENNIE M J. Claims for the anabolic effects of growth hormone: a case of the Emperor’s new clothes?[J]. Br J Sports Med, 2003, 37: 100.
[22]. KEIJI I, EMINA I, KIM D S, et al. Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice[J]. J Physiol, 2004, 560: 341-349.
[23]. LEE J S. Regulation of muscle mass by myostatin. Annu Rev Cell Dev Biol, 2004, 20:61-86.
[24]. GOLDSPINK G. Age-related loss of skeletal muscle function: impairment of gene expression[J]. J Musculoskelet Neuronal Interact, 2004,4(2):143-147.
[25]. KIM J S, CROSS J M, BAMMAN M M, et al. Impact of resistance loading on myostain expression and cell cycle regulation in young and older men and women[J]. Am J physiol Endocrinol Metab, 2005, 288(6): E1110-1119.
[1]. Mauro A. The satellite cell of skeletal muscle implantation[J]. J Biophys Biochem Cytol, 1961,9:493~496
[2]. Ferrari G, Cusella D,Angelis G,et al. Muscle regeneration by bone marrow—derived myogenic progenitors[J]. J Cell Biol, 1999, 147(4): 869~878
[3]. Sehultz E , McCormick KM.Skeletal muscle satellite cells[J]. Rev Physiol Biochem Pharmacol, 1994, 123: 213~257
[4]. Ordabl CP, wiuis RA, and Denetclaw W. Determination and morphogenesis inmyogenic progenitor cells: an experimental embryological approach. Curt Top Dev Biol, 2000, 48: 319~367
[5]. Ordabl CP.Myogenic shape —shifters. J Cel Biol,1999,147:695~698
[6]. De Angelis L,Berghella L,Coletta M,et a1.Skeletal myogenic progenitors originating from embryonic dorsal aorta coexpress endothelial and myogenic markers an d contribute to postnatal muscle growth and regeneration.J Cell Biol,1999,147 :869~878
[7]. Shi X, Garry DJ. Muscle stem cells in development, regeneration, and disease. Genes Dev, 2006 ;20(13):1692-708
[8]. Schultz E. Satellite Cell Proliferative Compartments in Growing Skeletal Muscles Developmental Biology, 1996,175(1):84-94
[9]. Bischoff R. The satellite cell and muscle regeneration. Myology, 1994, 97~118
[10]. Pavlath G. Isolation, purification and growth of skeletal muscle cells. Methods of Molecular Medicine: Human Cell Culture Protocols. 1996,307~318
[11]. Chen J, Goldhamer D. Skeletal muscle stem cells. Reprod Biol Endocrin 2003, 1: 101~107
[12]. Carlson B, Factors influencing the repair and adaptation of muscle in aged individuals: satellite cells and innervation. J Gerontol, 1995, 50A:96~100
[13]. Roth S, Martel G, Ivey F, et al. Skeletal muscle satellite cell populations in healthy young and older men and women. Anat Rec 2000; 260:351-358
[14]. Chultz E, Jaryszak D. Effects of skeletal muscle regeneration on the proliferation potential of satellite cells. Mech Aging Dev, 1985,30:63-72
[15]. Gibson M, Schultz E. Age-related difference in the absolute number of satellite cells in rat soleus and extensor digitorum longus muscle. Musc Nerve. 1983, 6:574~580
[16]. Gibson MC and Schultz E.Distribution of satelite cells and their relationship to specific fiber types in soleus and extensor digitorum longus muscle.Anat Rec,1982,202: 329—337
[17]. Asakura A, Seale P, Girgis-Gabardo A, et al. Myogenic specification of sidepopulation cells in skeletal muscle. J Cell Biol, 2002,159:123~134
[18]. Goldring K, Partridge T, Watt D. Muscle stem cells. J Pathol 2002;197:457~467
[19]. Vierck J, Reilly B, Hossner K, et a1. Satellite cell resulation following myotrauma caused by resistance exercise[J]. Cel Biol Int, 2000, 24: 263—272
[20]. 沈燕国,徐建光,顾玉东. 成肌调节因子 MyoD 和 Myf-5 在人体失神经骨骼肌中的表达及其临床意义[J]. 复旦大学学报, 2002, 29 (4): 264～267
[21]. Braun T, Rudinick MA , Arnold HH , et al . Targeted inactivation of the mouse regulatory gene Myf25 results in distal rib development and early postnatal death in homoxygous mouse mutant[J] . Cell ,1992 ,71 :369
[22]. Rudinick BT,Hinuma S, Jaenish R. MyoD or Myf25 is required for the formation of skeletal muscle[J] . Cell ,1993 ,75 :1351
[23]. Cooper RN ,Taybukhsh S ,Mouly G, et al . In vivo satellite cell activation via Myf-5 and MyoD in regenerating mouse skeletal muscle[J] . J Cell Sci ,1999 ,112 :2895.
[24]. Caroni P. Activity-sensitive signaling by muscle-deriver insulin like growth factors in the developing and regenerating neuromuscular system[J] . Annu N Y Acad Sci , 1993 , 692 : 209～222.
[25]. DeVol DL,Rotwein P,Sadow JL,et a1.Activation of insulin-like growth factor gene expression during work- induced skeletal muscle growth [J]. Am J Physiol, 1990, 259(1 Pt 1): E89-95
[26]. Yang H, Alnaqeeb M, Simpson H, et al. Changes in muscle fibre type, muscle mass and IGF- I gene expression in rabbit skeletal muscle subjected to stretch[J]. J Anat, 1997, 190 (Pt4):613- 622.
[27]. Yang S, Alnaqeeb M, Simpson H, et al. Cloning and characterization of an IGF- I isoform expressed in skeletal muscle subjected to stretch [J]. J Muscle Res Cell Motil, 1996,17(4):487-495.
[28]. Musaro A, MeCullagh K, Paul A, et al. Localized IGF-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle[J]. NatGenet, 200l, 27(2):195- 200.
[29]. Coleman ME, DeMayo F, Yin KC, et al. Myogenic vector expression of insulin- like growth factor I stimulates muscle cell differentiation and myofiberhypertrophy intransgenic mice[J]. J Biol Chem, 1995, 270(20):12109~12116
[30]. Barton-Davis ER, Shoturma DI, Musaro A, et al. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function Proc Natl Acad Sci USA. 1998, 95:15603~15607
[31]. Stewart CE, Rotwein P. Insulin-like Growth Factor-II is an autocrine survival factor for differentiating myoblasts[J]. J Biol Chem, 1996, 271:11330~11338
[32]. Florini JR, Magri KA, Ewton DZ, et al. “Spontaneous” differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II[J]. Cancer Res, 1991,51:5997~6000
[33]. Sheehan SM, Ronald E. Allen, Skeletal muscle satellite cell proliferation in response to members of the fibroblast growth factor family and hepatocyte growth factor. J Cell Physiol, 1999,181(3):499~506
[34]. Sheehan SM, Tatsumi R, Temm-Grove CJ, et al. HGF is an autocrine growth factor for skeletal muscle satellite cells in vitro[J]. Muscle Nerve. 2000;23(2):239~245
[35]. Miller K, Thaloor D, Matteson S, et al. Hepatocyte growth factor affects satellite cell activation and differentiation in regenerating skeletal muscle[J]. Am J Physiol Cell Physiol 2002,278:C174~C181
[36]. McPherron AC, Lawler AM, Lee SJ. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member[J]. Nature, 1997, 387(6628):83-90
[37]. 杨威, 王琨, 陈岩, 等. 重组肌肉抑制素功能分析及其对鸡肌肉发育的抑制作用[J ]. 生物化学与生物物理学报, 2003, 35 (11) : 1016-1022
[38]. Thomas M, Langley B, Berry C, et al. Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation[J]. J Biol Chem, 2000, 275: 40235-40243
[39]. Michael P, Spiller, Ravi Kambadur, et al. The myostatin gene is a downstream target gene of basic helix-loop-helix transcription factor MyoD [J]. Molecular and Cellular Biology, 2002, 22 (20) : 7066~7082.
[40]. Langley B, Thomas M, Bishop A, et al. Myostatin inhibits myoblast differentiation by down –regulating MyoD expression [J]. The Journal of Biological Chemistry, 2002, 277 (51) : 9831-49840
[41]. Rosenblatt JD, Yang D and Parry DJ. Satellite cell activity is required forhypertrophy of overload adult rat muscle [J]. Muscle Nerve, 1994,17: 608~613
[42]. Tatsumi R, Sheehan SM, Wasaki HI, et al. Mechanical Stretch Induces Activation of Skeletal Muscle Satellite Cells in Vitro[J]. Experimental Cell Research , 2001, 267: 107–114
[43]. Grounds MD. Muscle regeneration: molecular aspects and therapeutic implications. Curt Opin Neurol, 1999, 12: 535-543
[44]. Vierck J, Oreilly B, Hossner K, et a1. Satellite cell regulation following myotrauma caused by resistance exercise[J]. Cel Biol Int, 2000, 24(5): 263~272
[45]. 周锦琳.急性运动对大鼠骨骼肌卫星细胞增值能力和不同 pH 值对骨骼肌细胞胞浆 Ca2+代谢的影响。北京体育大学博士学位(毕业)论文,2003 年 4 月
[46]. 史仍飞,危小焰,卞玉华.机械牵拉刺激对大鼠骨骼肌卫星细胞增殖的影响.体育科学,2007,收录