中医肿瘤学家周岱翰教授学术思想临床经验研究
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摘要
目的：
周岱翰教授是全国较早从事中医肿瘤研究的中医肿瘤学专家,他从事肿瘤的研究有40余年,为研究、发展中医肿瘤学积累了丰富的宝贵的经验,在中医肿瘤领域作出了许多开创性的工作,整理、总结周岱翰教授临床经验与学术思想具有重要的学术价值与意义。文章总结周岱翰教授学术思想、临床治癌经验,为进一步推广名老中医的临床经验,初步形成传承名老中医学术思想、临床经验的方法；为中医药临床诊疗水平的提高、中医学术思想的不断丰富和发展作出贡献。
方法：
1、文献整理：对周教授的学生、弟子所完成的反映周教授学术思想的论文、著作加以整理、分析,归纳周教授的学术思想。
2.学习笔记整理：对本人跟师笔记、学习心得或临床经验体会进行整理。总结周教授临床中对中医理论、中医经典、中医肿瘤所提出的新见解、新观点。
3.医案整理：对周教授应用中医药治疗肿瘤患者的典型医案进行评析和小结,总结周教授对各病的认识和常用方药,分析其运用中医理论指导治疗该病的独到之处。进一步总结周教授的临床治癌经验。
4.病案统计：建立处方数据库,采用统计软件包SPSS简体中文19.0联合Excel软件进行数据管理和数据挖掘分析数,对处方进行聚类分析,分析周教授的用药特点。
结果：
周教授长期致力于完善中医肿瘤学内容体系,推动中医肿瘤学科形成,为中医肿瘤学作为中医学科发展作出了重要贡献。其学术思想和临床经验如下：
(1)推崇《伤寒杂病论》,诠释中医肿瘤学的学术内涵和辨证规范。强调肿瘤的辨证施治规范的形成始于《伤寒杂病论》,中医肿瘤学的辨证施治也遵循《伤寒杂病论》的法度,同样须根据各种临床证候,辨明病属寒热虚实,病在何脏何腑,属何经脉,而灵活运用六经的辨证方法。
(2)首倡放射反应和放射损害属”火邪”、”热毒”论,辨证归属“温病”范畴,发展和丰富温病学说。治疗首推养阴清热,祛邪消瘤。
(3)首提“带瘤生存”的学说,提倡个体化治疗。周教授根据临床实践,强调恶性肿瘤是一种局部属实,整体属虚的一类慢性疾病,癌瘤的病机是“毒发五脏,毒根深茂藏”。周教授认识到中晚期癌症根治不切实际,对中晚期癌症病人治疗的目的不应再是消灭癌瘤,而应着眼于减轻症状,改善生活质量,延长生存时间,与癌“和平共处”。基于此认识,他率先提出“带瘤生存”的概念。中医治癌的特点是整体观念和辨证论治,治疗方法或祛邪消瘤,或扶正补虚,因机体与肿瘤即整体和局部或本与标之间的关系而定,而扶正祛邪法应用于中晚期癌症的全过程。从观念上摒弃了肿瘤的“过度治疗”,使无法治愈的肿瘤患者保持良好的生活质量,促进了肿瘤的合理化和人性化治疗。
(4)临床诊疗特色：强调“辨病”与“辨证”相结合的治疗肿瘤原则,提倡治病求本,而急则治其标及标本兼治是为变法。重视望神察色观舌切脉合参,了解疾病的现状和病史,探索病因病机,掌握证候特点,判断预后的吉凶,指导临床治疗。
(5)临床用药特点：抗肿瘤中药,首推《神农本草经》,常用苦参、黄芪、人参、斑蝥、蟾蜍、蟪虫、露蜂房、附子、茵陈蒿、败酱、薏苡仁、白英、桃仁、大黄、丹参、徐长卿、海藻、鳖甲、夏枯草、连翘、芍药,女贞子、肉苁蓉、续断、五味子、枸杞、茯苓、当归、山茱萸、杜仲、薯蓣等扶正抗癌治疗,取得明显疗效。在长期的临床实践中,教授不仅善用古方,而且根据多年的临床经验和体会,注重现代医学实验与中医肿瘤临床结合进行研究,化裁古方,白拟新方。如莲花片、清肝消癥丸、参桃软肝肝方治疗原发性肝癌,鹤蟾片、清金得生片治疗支气管肺癌,解毒得生煎治疗大肠癌,参芪固本膏用于癌症化疗的骨髓保护(包括化疗前预防和化疗后恢复),以及癌症的康复治疗。他主持的“鹤蟾片治疗肺癌的研究”获1986年全国中医药重大科技成果乙等奖,“莲花片”获广东省科技成果三等奖。
(6)医案整理方面：收集临床常见肿瘤,如肺癌、肝癌、肠癌门诊和病房典型病例,进行医案整理和分析,总结认为：肺癌的发病多因正气先虚,邪毒乘虚而入,致肺气闭郁,肃降无权,痰浊内生而成,需从痰、瘀、毒、虚辨治,首重解毒除痰消瘤,益气养阴补肺；肝癌是一种以局部病变为主的全身性疾病,其发病背景多有慢性肝炎、肝硬变致瘀毒内聚、肝瘀脾虚,而肝功能损害(瘀毒、脾虚)既是疾病的演变结果,也是影响治疗效果的主要矛盾。因此,保肝、护肝须贯彻始终,或健脾保肝,或清热保肝,或养阴保肝,注意临症辨证选用,强调清肝利胆,健脾益气；治疗大肠癌,周师认为大肠为六腑之一,六腑以通为用,以降为顺,时时保持大便通畅,泻下腑中浊毒、瘀血,使邪有出路,在治疗中需贯穿始终。
(7)用药规律统计结果：选取周岱翰教授近3年来部分肺癌、肝癌、肠癌合格病案,详细记录患者的辨证诊断、症状、舌脉、处方,建立Excel数据库,共收集313诊次,其中106诊次,肝111诊次,肠癌96诊次。采用统计软件包SPSS简体中文19.0联合Excel软件进行数据管理和数据挖掘分析。先对所有药物进行使用频数统计,再对药物进行系统聚类分析。聚类分析得出周岱翰教授在治疗肺癌临证核心用药为：党参,白芍,守宫,法半夏,石上柏,厚朴,浙贝母,猫爪草,葶苈子,鱼腥草,山海螺；肝癌临证核心用药为：党参,土鳖虫,半枝莲,溪黄草,女贞子,八月札,龙葵草,茵陈,栀子,柴胡；肠癌临证常用药物为：党参,白芍,莪术,茯苓,白英草,肿节风,山慈菇,蒲公英,葛根,蛇舌草,苦参,白术,夏枯草,白头翁,木香,黄芩,大黄,虎杖,桂枝,枳壳,槐花,仙鹤草。
Study objective:
Professor Zhou Daihan is one of the earliest Chinese medicine cancer research oncology specialist, he engaged in cancer research40years, accumulated a wealth of valuable experience in the field of cancer medicine for research, development of Chinese oncology, has made many pioneering work, reorganize, summarize Professor Zhou Daihan clinical experience and academic thought has important academic value and significance. The article analyzes Professor Zhou Daihan Clinical experience in the treatment of cancer and the academic thought that Further promote the Skillful of the old Chinese medicine doctor's clinical experience, Forms the inheritance skillful old Chinese clinical experience and effective method of science initially, For the Chinese medicine clinical diagnosing and treating level's enhancement, the Chinese medicine academic thought are unceasingly rich and the development make the contribution.
Method:
1. Literature reorganization:Collate and analysis the papers or books that reflection of academic thinking of Professor Zhou Daihan from Zhou's students, to Induces Professor Zhou Daihan academic thought.
2. Organize study notes:Collate the learning experience and clinical experience that I am learning with the teacher. Summary the clinical experience, New opinion, new viewpoint of Professor Zhou Daihan.
3. Medical record reorganization:Carries on the summary to teacher using the Chinese medicine treatment tumor patient's typical medical notes, Summary of teacher awareness of the disease and commonly used herbs, Analysis of the use of traditional Chinese medicine theory to guide the unique treatment of the disease. Further summarizes teacher's Clinical experience in the treatment of cancer.
4. Medical record statistics:Establishment prescription database, Using data mining methods, Carries on the cluster analysis and the relatedness analysis to the prescription, uses the statistical method to analyze the Mr. Zhou medication characteristic.
Result:
Professor Zhou Daihan devotes for a long time to the consummation Chinese medicine oncology content system, impetus Chinese medicine tumor discipline formation, made significant contributions on the Chinese medicine oncology that Established and the development as a traditional Chinese medicine important independent branch. The academic thoughts and clinical experience as follows:
1. Respected "Typhus Various illnesses To discuss", Annotation Chinese medicine oncology academic connotation and dialectical standard. Stressed that the tumor dialectical treats the standard the formation to begin in "Typhus Various illnesses To discuss"; The Chinese medicine oncology dialectical treats also follows "Typhus Various illnesses Discuss" the law, Similarly must act according to each kind of clinical card period of five days, distinguishes clearly sickness is the cold and heat actual situation, gets sick in HeZang, HeFu the internal organs, is what passages through which vital energy circulates, but utilizes the six Confucian classics nimbly the dialectical method.
2. Originates the emission to respond and to emit the harm is "the fire is evil","Toxic heat" theory, Syndrome attributable to "warm diseases" category, development and rich various diseases accompanied by fever theory. The treatment regards raises the cloudy refrigeration, eliminateing the pathogenic factor disappears the lump.
3. First proposed "surviving with cancer" theory, advocates the individuation treatment. Professor Zhou acts according to the clinical practice, stressed that the malignant tumor is one kind partial is Shi, the whole is a Xu kind of chronic vigorous sickness, the cancer lump's pathogenesis is "proceeds from the five internal organs poisonously, the poisonous root buries deeply". Professor Zhou realized that permanently cures impractically to the mid and late stage cancer, treats the goal to the mid and late stage cancer patient not should again eliminates the cancer lump, but should focus in reduces the symptom, improvement quality of life, extension life, with cancer "peaceful coexistence". Based on this understanding, he takes the lead proposes "the belt lump survival" the concept. Treats the cancer the characteristic is the concept of viewing the entire situation and the diagnosis and treatment, the method of treatment or eliminateing the pathogenic factor disappears the lump, or straightens up makes up empty, because organism and the tumor are the whole and partial or this and between the sign relations decide, but straightens up袪evil method often to apply in the mid and late stage cancer's entire process. Abandoned the tumor from the idea "to treat excessively", causes the tumor patient who was unable to cure maintains the good quality of life, promoted the tumor rationalization and the user-friendly treatment.
4. Clinical diagnosing and treating characteristic:Stressed that "distinguishes the treatment tumor principle which sickness" and "dialectical" unifies, advocated that treats an illness asks the book, but then governs its sign and treats the symptoms and the causes is anxiously is the political reform. The value observes the patient's expression observes the color view tongue to feel the pulse gathers the senate, understood that disease's present situation and the medical history, the exploration cause of disease pathogenesis, grasps the card period of five days characteristic, the judgment prognosis good and bad fortune, the instruction clinical care.
5. Clinical medication characteristic:Anti-tumor traditional Chinese medicine application, Regards "Shen nong Bencao Jing", The commonly used Kushen, Huangqi, Renshen, Banmao, Chanchu, Zhechong, Lufengfang, Fuzi, Yinchenhao, Baijiancao, Yiyiren, Baiyingcao, Taoren, Dahuang, Danshen, Xuchangqin, Haizao, Biejia, Xiakucao, Lianqiao, Shaoyao, Nvzhenzi, Rouchongrong, Xuduan, Wuweizi, Gouqizi, Fuling, Danggui, Shanzhuyu, Duzhong, Shuyu and so on straighten up the anticancer treatment treatment, obtains the obvious curative effect. In the long-term clinical practice, teacher not only makes good use of the ancient medical prescription, moreover acts according to many year clinical experiences and the experience, pays great attention the modern medicine experiment and the Chinese medicine tumor clinical union conducts the research, melts cuts the ancient medical prescription, from plans the new side. Like the lotus flower petal, the clear liver di sappear the pill, senate peach soft liver liver side treatment primary liver cancer, the crane toad piece, the clear gold live the piece treatment bronchial tube lung cancer, detoxifies lives fries treats the colon cancer. He managed "the crane toad piece treatment lung cancer research" to attain in1986the national Chinese medicine significant scientific and technical payoffs class B prize,"the lotus flower petal" won Guangdong Province scientific and technical payoffs third prize.
6. Medical record reorganization aspect:Collects clinical common tumor, such as lung cancer, liver cancer, colorectal cancer from outpatient service and the hospital ward typical case, to reorganization and analysis medical notes, result:Mostly due to lung cancer is Zhengqi xu, Xieqi take advantage of the lung caused by QiBi of the lung, Su-down power, phlegm endogenous made to be from the sputum, blood stasis, drugs, virtual Benji, the first heavy detoxification expectorant Xiaoliu, nourishing lungs; Liver cancer is a kind of local disease based systemic disease, its incidence has more than the background of chronic hepatitis, cirrhosis caused Ecchymosis cohesion, stasis liver and spleen xu, and liver dysfunction (Ecchymosis, spleen xu) is the evolution of the disease results, but also affect the treatment of the principal contradiction. Therefore, protecting the liver to be consistent, or enhance spleen and protect the liver, or clears the thermal protects liver, or yangying protects liver, attention to clinical disease syndromes selection, emphasizing clearing liver heat and helping gallbladder, health caring spleen adding Qi; To treatment of colorectal cancer, Pro. Zhou That the colon is one of six internal organs, Six Fu-organs theory, in order to fall down, from time to time to keep stool, diarrhea organs in the toxic cloud, blood stasis, so that evil has a way out, in need throughout the treatment.
7.Medical record statistical result:Selects Professor Zhou Daihan Daihan to be for the past three years partial the medical record which the lung cancer, liver cancer, cancer of the intestines first three examine, the detailed record patient's dialectical diagnosis, the symptom, the tongue arteries, the prescription, establish Excel the database, altogether collects313examines the time, lung cancer106examples, liver cancer111examples, cancer of the intestines96examples. Uses the statistical software package SPSS simplified Chinese19.0to unite the Excel software to carry on the data management and the data mining analysis. Carries on the use frequency statistics first to all medicines, then carries on the system cluster analysis. The cluster analysis obtains Professor Zhou Daihan Daihan in the treatment lung cancer near the card core medication is:shougong, fabanxia, shishangbai, houpu, zhebeimu, maozhuacao, tinglizi, yuxingcao, shanhailuo; Liver cancer near the card core medication is:tubiechong, xihuangcao, nvzhenzi, bayuezha, longkuicao, yinchen, zhizi, chaihu; Cancer of the intestines near the card commonly used medicine is:ezhu, fuling, baiyingcao, zhongjiefeng, shancigu, pugongying, gegen, sheshecao, kushen, baizhu, xiakucao, baitouwen, muxiang, huangqin, dahuang, huzhang, guizhi, zhike, huaihua, xianhecao.
周岱翰教授是全国较早从事中医肿瘤研究的中医肿瘤学专家,他从事肿瘤的研究有40余年,为研究、发展中医肿瘤学积累了丰富的宝贵的经验,在中医肿瘤领域作出了许多开创性的工作,整理、总结周岱翰教授临床经验与学术思想具有重要的学术价值与意义。文章总结周岱翰教授学术思想、临床治癌经验,为进一步推广名老中医的临床经验,初步形成传承名老中医学术思想、临床经验的方法；为中医药临床诊疗水平的提高、中医学术思想的不断丰富和发展作出贡献。
方法：
1、文献整理：对周教授的学生、弟子所完成的反映周教授学术思想的论文、著作加以整理、分析,归纳周教授的学术思想。
2.学习笔记整理：对本人跟师笔记、学习心得或临床经验体会进行整理。总结周教授临床中对中医理论、中医经典、中医肿瘤所提出的新见解、新观点。
3.医案整理：对周教授应用中医药治疗肿瘤患者的典型医案进行评析和小结,总结周教授对各病的认识和常用方药,分析其运用中医理论指导治疗该病的独到之处。进一步总结周教授的临床治癌经验。
4.病案统计：建立处方数据库,采用统计软件包SPSS简体中文19.0联合Excel软件进行数据管理和数据挖掘分析数,对处方进行聚类分析,分析周教授的用药特点。
结果：
周教授长期致力于完善中医肿瘤学内容体系,推动中医肿瘤学科形成,为中医肿瘤学作为中医学科发展作出了重要贡献。其学术思想和临床经验如下：
(1)推崇《伤寒杂病论》,诠释中医肿瘤学的学术内涵和辨证规范。强调肿瘤的辨证施治规范的形成始于《伤寒杂病论》,中医肿瘤学的辨证施治也遵循《伤寒杂病论》的法度,同样须根据各种临床证候,辨明病属寒热虚实,病在何脏何腑,属何经脉,而灵活运用六经的辨证方法。
(2)首倡放射反应和放射损害属”火邪”、”热毒”论,辨证归属“温病”范畴,发展和丰富温病学说。治疗首推养阴清热,祛邪消瘤。
(3)首提“带瘤生存”的学说,提倡个体化治疗。周教授根据临床实践,强调恶性肿瘤是一种局部属实,整体属虚的一类慢性疾病,癌瘤的病机是“毒发五脏,毒根深茂藏”。周教授认识到中晚期癌症根治不切实际,对中晚期癌症病人治疗的目的不应再是消灭癌瘤,而应着眼于减轻症状,改善生活质量,延长生存时间,与癌“和平共处”。基于此认识,他率先提出“带瘤生存”的概念。中医治癌的特点是整体观念和辨证论治,治疗方法或祛邪消瘤,或扶正补虚,因机体与肿瘤即整体和局部或本与标之间的关系而定,而扶正祛邪法应用于中晚期癌症的全过程。从观念上摒弃了肿瘤的“过度治疗”,使无法治愈的肿瘤患者保持良好的生活质量,促进了肿瘤的合理化和人性化治疗。
(4)临床诊疗特色：强调“辨病”与“辨证”相结合的治疗肿瘤原则,提倡治病求本,而急则治其标及标本兼治是为变法。重视望神察色观舌切脉合参,了解疾病的现状和病史,探索病因病机,掌握证候特点,判断预后的吉凶,指导临床治疗。
(5)临床用药特点：抗肿瘤中药,首推《神农本草经》,常用苦参、黄芪、人参、斑蝥、蟾蜍、蟪虫、露蜂房、附子、茵陈蒿、败酱、薏苡仁、白英、桃仁、大黄、丹参、徐长卿、海藻、鳖甲、夏枯草、连翘、芍药,女贞子、肉苁蓉、续断、五味子、枸杞、茯苓、当归、山茱萸、杜仲、薯蓣等扶正抗癌治疗,取得明显疗效。在长期的临床实践中,教授不仅善用古方,而且根据多年的临床经验和体会,注重现代医学实验与中医肿瘤临床结合进行研究,化裁古方,白拟新方。如莲花片、清肝消癥丸、参桃软肝肝方治疗原发性肝癌,鹤蟾片、清金得生片治疗支气管肺癌,解毒得生煎治疗大肠癌,参芪固本膏用于癌症化疗的骨髓保护(包括化疗前预防和化疗后恢复),以及癌症的康复治疗。他主持的“鹤蟾片治疗肺癌的研究”获1986年全国中医药重大科技成果乙等奖,“莲花片”获广东省科技成果三等奖。
(6)医案整理方面：收集临床常见肿瘤,如肺癌、肝癌、肠癌门诊和病房典型病例,进行医案整理和分析,总结认为：肺癌的发病多因正气先虚,邪毒乘虚而入,致肺气闭郁,肃降无权,痰浊内生而成,需从痰、瘀、毒、虚辨治,首重解毒除痰消瘤,益气养阴补肺；肝癌是一种以局部病变为主的全身性疾病,其发病背景多有慢性肝炎、肝硬变致瘀毒内聚、肝瘀脾虚,而肝功能损害(瘀毒、脾虚)既是疾病的演变结果,也是影响治疗效果的主要矛盾。因此,保肝、护肝须贯彻始终,或健脾保肝,或清热保肝,或养阴保肝,注意临症辨证选用,强调清肝利胆,健脾益气；治疗大肠癌,周师认为大肠为六腑之一,六腑以通为用,以降为顺,时时保持大便通畅,泻下腑中浊毒、瘀血,使邪有出路,在治疗中需贯穿始终。
(7)用药规律统计结果：选取周岱翰教授近3年来部分肺癌、肝癌、肠癌合格病案,详细记录患者的辨证诊断、症状、舌脉、处方,建立Excel数据库,共收集313诊次,其中106诊次,肝111诊次,肠癌96诊次。采用统计软件包SPSS简体中文19.0联合Excel软件进行数据管理和数据挖掘分析。先对所有药物进行使用频数统计,再对药物进行系统聚类分析。聚类分析得出周岱翰教授在治疗肺癌临证核心用药为：党参,白芍,守宫,法半夏,石上柏,厚朴,浙贝母,猫爪草,葶苈子,鱼腥草,山海螺；肝癌临证核心用药为：党参,土鳖虫,半枝莲,溪黄草,女贞子,八月札,龙葵草,茵陈,栀子,柴胡；肠癌临证常用药物为：党参,白芍,莪术,茯苓,白英草,肿节风,山慈菇,蒲公英,葛根,蛇舌草,苦参,白术,夏枯草,白头翁,木香,黄芩,大黄,虎杖,桂枝,枳壳,槐花,仙鹤草。
Study objective:
Professor Zhou Daihan is one of the earliest Chinese medicine cancer research oncology specialist, he engaged in cancer research40years, accumulated a wealth of valuable experience in the field of cancer medicine for research, development of Chinese oncology, has made many pioneering work, reorganize, summarize Professor Zhou Daihan clinical experience and academic thought has important academic value and significance. The article analyzes Professor Zhou Daihan Clinical experience in the treatment of cancer and the academic thought that Further promote the Skillful of the old Chinese medicine doctor's clinical experience, Forms the inheritance skillful old Chinese clinical experience and effective method of science initially, For the Chinese medicine clinical diagnosing and treating level's enhancement, the Chinese medicine academic thought are unceasingly rich and the development make the contribution.
Method:
1. Literature reorganization:Collate and analysis the papers or books that reflection of academic thinking of Professor Zhou Daihan from Zhou's students, to Induces Professor Zhou Daihan academic thought.
2. Organize study notes:Collate the learning experience and clinical experience that I am learning with the teacher. Summary the clinical experience, New opinion, new viewpoint of Professor Zhou Daihan.
3. Medical record reorganization:Carries on the summary to teacher using the Chinese medicine treatment tumor patient's typical medical notes, Summary of teacher awareness of the disease and commonly used herbs, Analysis of the use of traditional Chinese medicine theory to guide the unique treatment of the disease. Further summarizes teacher's Clinical experience in the treatment of cancer.
4. Medical record statistics:Establishment prescription database, Using data mining methods, Carries on the cluster analysis and the relatedness analysis to the prescription, uses the statistical method to analyze the Mr. Zhou medication characteristic.
Result:
Professor Zhou Daihan devotes for a long time to the consummation Chinese medicine oncology content system, impetus Chinese medicine tumor discipline formation, made significant contributions on the Chinese medicine oncology that Established and the development as a traditional Chinese medicine important independent branch. The academic thoughts and clinical experience as follows:
1. Respected "Typhus Various illnesses To discuss", Annotation Chinese medicine oncology academic connotation and dialectical standard. Stressed that the tumor dialectical treats the standard the formation to begin in "Typhus Various illnesses To discuss"; The Chinese medicine oncology dialectical treats also follows "Typhus Various illnesses Discuss" the law, Similarly must act according to each kind of clinical card period of five days, distinguishes clearly sickness is the cold and heat actual situation, gets sick in HeZang, HeFu the internal organs, is what passages through which vital energy circulates, but utilizes the six Confucian classics nimbly the dialectical method.
2. Originates the emission to respond and to emit the harm is "the fire is evil","Toxic heat" theory, Syndrome attributable to "warm diseases" category, development and rich various diseases accompanied by fever theory. The treatment regards raises the cloudy refrigeration, eliminateing the pathogenic factor disappears the lump.
3. First proposed "surviving with cancer" theory, advocates the individuation treatment. Professor Zhou acts according to the clinical practice, stressed that the malignant tumor is one kind partial is Shi, the whole is a Xu kind of chronic vigorous sickness, the cancer lump's pathogenesis is "proceeds from the five internal organs poisonously, the poisonous root buries deeply". Professor Zhou realized that permanently cures impractically to the mid and late stage cancer, treats the goal to the mid and late stage cancer patient not should again eliminates the cancer lump, but should focus in reduces the symptom, improvement quality of life, extension life, with cancer "peaceful coexistence". Based on this understanding, he takes the lead proposes "the belt lump survival" the concept. Treats the cancer the characteristic is the concept of viewing the entire situation and the diagnosis and treatment, the method of treatment or eliminateing the pathogenic factor disappears the lump, or straightens up makes up empty, because organism and the tumor are the whole and partial or this and between the sign relations decide, but straightens up袪evil method often to apply in the mid and late stage cancer's entire process. Abandoned the tumor from the idea "to treat excessively", causes the tumor patient who was unable to cure maintains the good quality of life, promoted the tumor rationalization and the user-friendly treatment.
4. Clinical diagnosing and treating characteristic:Stressed that "distinguishes the treatment tumor principle which sickness" and "dialectical" unifies, advocated that treats an illness asks the book, but then governs its sign and treats the symptoms and the causes is anxiously is the political reform. The value observes the patient's expression observes the color view tongue to feel the pulse gathers the senate, understood that disease's present situation and the medical history, the exploration cause of disease pathogenesis, grasps the card period of five days characteristic, the judgment prognosis good and bad fortune, the instruction clinical care.
5. Clinical medication characteristic:Anti-tumor traditional Chinese medicine application, Regards "Shen nong Bencao Jing", The commonly used Kushen, Huangqi, Renshen, Banmao, Chanchu, Zhechong, Lufengfang, Fuzi, Yinchenhao, Baijiancao, Yiyiren, Baiyingcao, Taoren, Dahuang, Danshen, Xuchangqin, Haizao, Biejia, Xiakucao, Lianqiao, Shaoyao, Nvzhenzi, Rouchongrong, Xuduan, Wuweizi, Gouqizi, Fuling, Danggui, Shanzhuyu, Duzhong, Shuyu and so on straighten up the anticancer treatment treatment, obtains the obvious curative effect. In the long-term clinical practice, teacher not only makes good use of the ancient medical prescription, moreover acts according to many year clinical experiences and the experience, pays great attention the modern medicine experiment and the Chinese medicine tumor clinical union conducts the research, melts cuts the ancient medical prescription, from plans the new side. Like the lotus flower petal, the clear liver di sappear the pill, senate peach soft liver liver side treatment primary liver cancer, the crane toad piece, the clear gold live the piece treatment bronchial tube lung cancer, detoxifies lives fries treats the colon cancer. He managed "the crane toad piece treatment lung cancer research" to attain in1986the national Chinese medicine significant scientific and technical payoffs class B prize,"the lotus flower petal" won Guangdong Province scientific and technical payoffs third prize.
6. Medical record reorganization aspect:Collects clinical common tumor, such as lung cancer, liver cancer, colorectal cancer from outpatient service and the hospital ward typical case, to reorganization and analysis medical notes, result:Mostly due to lung cancer is Zhengqi xu, Xieqi take advantage of the lung caused by QiBi of the lung, Su-down power, phlegm endogenous made to be from the sputum, blood stasis, drugs, virtual Benji, the first heavy detoxification expectorant Xiaoliu, nourishing lungs; Liver cancer is a kind of local disease based systemic disease, its incidence has more than the background of chronic hepatitis, cirrhosis caused Ecchymosis cohesion, stasis liver and spleen xu, and liver dysfunction (Ecchymosis, spleen xu) is the evolution of the disease results, but also affect the treatment of the principal contradiction. Therefore, protecting the liver to be consistent, or enhance spleen and protect the liver, or clears the thermal protects liver, or yangying protects liver, attention to clinical disease syndromes selection, emphasizing clearing liver heat and helping gallbladder, health caring spleen adding Qi; To treatment of colorectal cancer, Pro. Zhou That the colon is one of six internal organs, Six Fu-organs theory, in order to fall down, from time to time to keep stool, diarrhea organs in the toxic cloud, blood stasis, so that evil has a way out, in need throughout the treatment.
7.Medical record statistical result:Selects Professor Zhou Daihan Daihan to be for the past three years partial the medical record which the lung cancer, liver cancer, cancer of the intestines first three examine, the detailed record patient's dialectical diagnosis, the symptom, the tongue arteries, the prescription, establish Excel the database, altogether collects313examines the time, lung cancer106examples, liver cancer111examples, cancer of the intestines96examples. Uses the statistical software package SPSS simplified Chinese19.0to unite the Excel software to carry on the data management and the data mining analysis. Carries on the use frequency statistics first to all medicines, then carries on the system cluster analysis. The cluster analysis obtains Professor Zhou Daihan Daihan in the treatment lung cancer near the card core medication is:shougong, fabanxia, shishangbai, houpu, zhebeimu, maozhuacao, tinglizi, yuxingcao, shanhailuo; Liver cancer near the card core medication is:tubiechong, xihuangcao, nvzhenzi, bayuezha, longkuicao, yinchen, zhizi, chaihu; Cancer of the intestines near the card commonly used medicine is:ezhu, fuling, baiyingcao, zhongjiefeng, shancigu, pugongying, gegen, sheshecao, kushen, baizhu, xiakucao, baitouwen, muxiang, huangqin, dahuang, huzhang, guizhi, zhike, huaihua, xianhecao.
引文
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[5]周岱翰,林丽珠,周宜强等.中医药对提高非小细胞肺癌中位生存期的作用研究[J].广州中医药大学学报.2005,22(4)：255—258.
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[8]朱华宇.周岱翰教授治疗支气管肺癌临证经验举要.中医药学刊,2003,21(1)：30-31.
[9]戴馨仪.鹤蟾片对荷瘤动物的实验研究.学术年会资料选篇,1986：177—181.
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[3]熊墨年,熊林楷.浅谈中医药治疗肿瘤的思路与优势.2007国际中医药肿瘤大会会刊,2007,108-109.
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[5]周岱翰,林丽珠,周宜强等.中医药对提高非小细胞肺癌中位生存期的作用研究[J].广州中医药大学学报.2005,22(4)：255—258.
[6]林丽珠,周岱翰.参桃软肝丸合并喜树碱对大肝癌的保肝抑瘤作用.广州中医药大学学报,2005,22(2)：101-105.
[7]林丽珠.周岱翰教授治疗原发性肝癌经验撷要.新中医,2002,34(10)：12.
[8]朱华宇.周岱翰教授治疗支气管肺癌临证经验举要.中医药学刊,2003,21(1)：30-31.
[9]戴馨仪.鹤蟾片对荷瘤动物的实验研究.学术年会资料选篇,1986：177—181.
[10]周岱翰,张伦,陈锐深,等.鹤蟾片治疗肺癌临床研究报告—附102例疗效分析.新中医,1986,(4)：31-33.
[11]戴馨仪, 陈林香,周岱翰等.固金磨积片抗肿瘤机理的研究[J].中药新药与临床药理,1997,8(3)：154-155.
[]2]周岱翰,沈美玉,刘伟胜等.固金磨积片治疗77例非小细胞肺癌[J].中国中西医结合外科杂志,1997,3(6)：383-384.
[13]陈林香,戴馨仪,周岱翰.清金得生片对化疗荷瘤小鼠的增效减毒作用研究[J].中医药学刊,2004,22(12)：2215.
[14]戴馨仪,陈林香,周岱翰.清金得生片抗肿瘤机理研究[J].中药新药与临床药理,2002,16(6)：360.
[15]陈林香, 戴馨仪,周岱翰.清金得生片对小鼠移植性肝癌细胞增生与凋亡的影响[J].肿瘤研究与临床试验,2003,15(3)：153.
[16]石世德,李任先.参桃软肝丸对荷肝癌小鼠的抑瘤作用及提高IL-2、NK活性的实验研究.中药新药与临床药理,2001；12(3)：216-218。
[17]戴馨仪,陈林香.参桃软肝丸对荷瘤动物抑瘤与免疫的实验研究.中国肿瘤,2001,10(7)：426-428.
[18]陈林香,戴馨仪。参桃软肝丸抗肿瘤实验及其诱导肿瘤细胞调亡的研究.肿瘤防治研究,2002,29(6)：473-474.
[19]陈林香,戴馨仪.参桃软肝丸对肿瘤生长及T淋巴细胞亚群的影响.肿瘤防治杂志,2002,9(3)：241-243.
[20]陈林香,戴馨仪.参桃软肝丸抗大鼠肝纤维化的实验研究.中医药学刊,2003,21(4)：519-520.
[21]林丽珠,周岱翰.参桃软肝丸合并喜树碱对大肝癌的保肝抑瘤作用.广州中医药大学学报,2005,22(2)：101-105.
[22]刘展华,周岱翰.参桃软肝丸治疗肝癌术后复发的临床观察.广州中医药大学学报2006,23(6)：467-471.
[23]周岱翰.肿瘤治验集要[M].广东：广东高等教育出版社,1997：121-122.
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